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Medroxyprogesterone for Endometriosis User Reviews (Page 4)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Medroxyprogesterone has an average rating of 5.7 out of 10 from a total of 92 reviews for the treatment of Endometriosis. 45% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Medroxyprogesterone

  • boots
  • Taken for 5 to 10 years
  • March 25, 2022

Depo Provera (medroxyprogesterone) "I was on the depo from age 15 to 21. I had no side effects (except for some minor spotting toward the end of the three month period), and did not have a menstrual cycle. However, my last several injections have been ineffective. I've been having a menstrual cycle with no bleeding, and tons of painful cysts for about a year. I'm not sure if the formula was changed or what, but I've since switched to the implant."

7 / 10
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  • hammy...
  • Taken for 6 months to 1 year
  • December 4, 2021

Depo Provera (medroxyprogesterone) "I initially started taking the Depo-Provera 7 months ago due to lengthy painful periods. Only bleed on the 2 weeks leading up to second injection. After 5 months, started getting horrible pelvic pain, ended up in the ED. Was discharged after 3 hours, because I was on the depo so they ruled out endo. Pain continued for another 3 weeks. Pain meds don't help. The pain stopped for about two weeks. Then it started again. I was sent to the ED again, and was told it is likely endometriosis. Was sent to my GP but was told I shouldn't be feeling endo pain on the depo. I still haven't gotten a laparoscopy. I am being told I need a mirena. Overall, the depo seemed worth it at first. No periods and no pain caused by periods is wonderful, but I am still experiencing endo pain. It really does depend on who you are and where you are in your life. Sometimes I wish I had my period back so I could get answers about endo ): I suffer from PTSD and GAD but the depo didn't make it worse. No weight gain."

5 / 10
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  • Birdly
  • Taken for less than 1 month
  • January 9, 2022

Depo Provera (medroxyprogesterone) "Although my Depo experience was in 2008, I thought I would chime in. I did not want to go on depo provera, I had been suffering with endometriosis for years and I had major concerns as I also suffer from multiple mood issues. I finally relented and booked a desperate appointment. I was to have 6 injections. When the nurse injected my first dose, her exact words were “you’re going to go crazy for the first few weeks.” WOW, great to know now that you’ve just injected me. Exactly 2 weeks after my injection without thinking I had a suicide attempt. I had also written a suicide note which I have no memory of. I’m not sure how, but I woke up the next day. Although very sick, I faked health to family and friends but could not get out bed. I was rushed to emerg a day later where the doctors where shocked I was alive. Took a year to recover."

1 / 10
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Frequently asked questions

  • Rachel
  • September 12, 2021

Depo Provera (medroxyprogesterone) "Depo Provera has changed my life for the better. I was never officially tested for it, but was thought to have Endometriosis. I used to get very painful cramps, nausea and vomiting if I was foolish enough to eat solids. My periods were very irregular, with only spotting some months but long stretches of bleeding other months. The longest continuous bleeding I had was just over two months. I had to have iron injections because I couldn't get enough from food and tablets. DEPO Provera stopped my periods, and I now have no pain, don't need to regularly take time off work, can eat all month around, can work out and play sports without fainting, and even donate blood! I find going to the doctors once every three months very convenient compared to other birth control methods I have tried. I did gain weight, and have to lose it back and then start watching how I eat a bit more carefully."

10 / 10
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  • Calib...
  • Taken for 1 to 2 years
  • September 27, 2016

"I've been on the pill form (Provera), 30mg once a day for almost 15 months now and have gained nearly 100 lbs. I kid you not. My doctor thought it was my thyroid but it was not. All of my hormone levels were normal when tested. It has to be the medicine. It has a bad reputation for weight gain and I have never struggled with weight in my entire life before getting on this med. I was put on it for endometriosis and ovarian cysts, but I am going to talk to my Obgyn about switching to something else because I am almost positive it at least contributed to my rapid weight gain. Like others said, I am also tired all day every day. Very little energy. I haven't gotten a period since a month or two after I started taking it. Not worth it though."

1 / 10
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Are you taking this medicine?

  • Dolores
  • Taken for 6 months to 1 year
  • February 4, 2022

Provera (medroxyprogesterone) "I experience severe as normal bleeding for 3 months straight heavy at times started in June saw the doctor she told me that the Mirena IUD would help but I broke out in a rash so I had that removed in July my next option was Provera ..I was told the bleeding would stop in 10 days but I bled for 3 months Non-Stop great news is it finally stopped at the end of October and hasnt came back as long as I stay on the 10 mg dose everyday ..I almost gave up because I could not deal with the heavy bleeding ..I had no life I stay home because i feared I I have an episode blood just gushing everywhere's.. believe me when I say it does eventually work for some it works sooner for some it takes longer you just have to be consistent with your dosage and the time that you take..provera has given me my life back"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 27, 2020

"I recently just started the Medroxyprogesterone 150mg shot for Endometriosis, a week ago was my first and only shot. Immediately after I got the shot I felt light headed and dizzy. Now you might think that I just do not like shots but I am actually perfectly fine with them. But this one was different. The dizziness never went away, then it became nausea and insomnia. Now it is a week later and I have blisters on my fingers, there is a rash all over my lower back, butt, and down the back of my thighs. I still can not sleep, I eat a lot more than I should, I am constantly dizzy, and I do not feel like myself."

1 / 10
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  • Anonymous
  • April 20, 2009

"I have used Provera for four years and have never suffered from any side effects. The only draw back is that my doctor insists that I have a period every 3 months. I take 10mg 3 times a day and this stops my periods and therefore all the problems that are associated with endometriosis. I only wish I could take the pills permanently."

10 / 10
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  • Tash
  • Taken for less than 1 month
  • February 1, 2020

Depo Provera (medroxyprogesterone) "I am now about 3 weeks into what can only be described as a long lasting nightmare. The day I received my first shot, I started experiencing what can only be described as menopausal symptoms. Not only has my recently stabilised depression completely gone out the window, I also have constant hot flushes, fatigue, mood swings and nausea. A pharmacist recommended Clonidine to help these issues, but it's a cost vs benefit thing... Clonidine gives me a different kind of fatigue and nausea, but (somewhat) curbs the hot flushes, so I tend to only take it every second day. I haven't gained any weight, but I also haven't lost any despite actively eating healthier and exercising. My weight hasn't fluctuated beyond gains/losses between 500g-1kg. I can't wait for the next 10 weeks to be over. The only reason I made the decision to move over from Nur-isterate was because of a country-wide stock shortage. This will never be worth it. I'd take excruciatingly painful periods over this hell any day."

1 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • May 25, 2018

Depo Provera (medroxyprogesterone) "In the past, I have tried various pills and the patch. With the Depo shot, it was nice to only have to get it every 3 months. The first 6 months or so, I had irregular periods, but after that my periods stopped completely. I was on the Depo shot for over 3 years and had more pros than cons. The only downside for me was the weight gain. I stopped taking the shot so my weight would come off...it didn't. I would advise extremely healthy diet and exercise if you want to be on the Depo shot."

8 / 10
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  • mattert
  • September 8, 2011

"I have irregular periods due to the endometriosis. I can bleed for weeks and heavy. My doctor gave me the prescription for medroxyprogesterone a long time ago and it was like a miracle for me. By the third day out of the ten that I had to take it for my long awaited bleeding stopped. I have never encountered any side effects from the medication at all and I have had to take it on many occasions. I am very grateful for the manufacturer of this medicine. I don't know where I would be without it today. So thank you so much."

10 / 10
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  • 456732
  • Taken for 1 to 2 years
  • December 6, 2022

Depo-subQ provera 104 (medroxyprogesterone) "I got sick of the pill, the pill never helped with my cramps and I had constant periods. For very heavy periods would have to change ultra tampons within an hour and a half. I have awful cramps, I’ve also passed over 20 kidney stones and my cramps are still worse. Then I started depo, I want to cry it has been amazing no cramps, no periods, no suffering. I wish I had started in my teen life would have been so much easier. Also if you have general joint pain to begin with, make sure you take your calcium and vitamin D!!! One year of taking it my hip and femur started becoming very painful and feeling empty? Not sure how to describe the feeling. However, once I started taking calcium plus vitamin d regularly it felt a lot better! (I also work a very very labor intensive job lifting over 150 pounds throughout the day so I already have joint issues) that was the only bad thing from the pill it’s just been fantastic otherwise!!!!"

10 / 10
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  • Sunsh...
  • Taken for less than 1 month
  • August 17, 2017

"I've missed periods for 2 years since stopping birth control and now been diagnosed with PCOS, and recently after an appendectomy, surgeon noticed signs of endometriosis. The idiotic new obgyn I went to had No idea what Either were. While even training a student, I heard a Lonng 45 min+ conversation between her and a head doctor who was trying to teach her what is was..while I was trying to leave, she came in and said endo was blood that gets stuck internally in wrong places... uggh my friend knew MUCH more about it and informed me the textbook definition etc. I've been on the 10 day med. to prompt a period so my lining doesn't build up too thick n cause cancer it's not working tho two 10 day scripts and nothing but sore huge breasts. I think its called methohydroxidone"

1 / 10
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  • Oodle...
  • November 30, 2015

"I took this medication two years ago and only received three shots before having to quit due to migraines. It thinned my hair, my bones, made me a raging lunatic. I still suffer from migraines. This drug did NOTHING to stop my endo. While on it, I needed to have 3 lapex surgeries and was always on Vicodin or Percocet for pain. If your doctor says to try this medication, I would RUN not walk to the nearest exit and go get a second opinion."

1 / 10
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  • Crysti
  • Taken for 1 to 6 months
  • July 3, 2024

"I ended up in the hospital due to a bowel blockage, which was caused by day 10 of my heavy bleeding period. I have endometriosis in my bowels. I was also severely anemic. My hospital-appointed gynecologist prescribed me some Provera, and it stopped my bleeding within a day! After I was discharged, he prescribed it to me with directions to take it after day 3 of my period, to once again stop the bleeding. It worked! I have since had the Mirena IUD placed, which gives off progesterone as well, and I haven't had any issues since. After 25 years of endometriosis, I wish I had known about this drug earlier!"

10 / 10
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  • ANB
  • Taken for 1 to 2 years
  • February 25, 2022

Depo Provera (medroxyprogesterone) "It has helped me a lot in terms of pain relief I have little to no pain since starting depo. However I am on a high dose. I take 300mg every 6 weeks because when I was on 150mg every month I still felt pain. Only side effect I have experienced is weight gain, I gained about 30 lbs since I started it in late 2020. I have also noticed that my pH becomes imbalanced way more easily since I've been on it but other than that I'm grateful for the relief."

8 / 10
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  • Lea
  • November 14, 2014

Depo Provera (medroxyprogesterone) "I have been on it now for 10 yrs & love it. Before I would be in bed for weeks with bad cramps, it was destroying my life. I get little cramping well the shot is due but I can live with that."

8 / 10
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  • Anonymous
  • March 5, 2009

Depo Provera (medroxyprogesterone) "I had extreme nausea and vomiting within a week of getting my first and ONLY shot of Depo-Provera."

3 / 10
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  • Flower
  • Taken for 1 to 6 months
  • October 9, 2019

Depo Provera (medroxyprogesterone) "I stopped depo about 3 months ago, I've been bleeding for two months. I've gained 30 pounds. I'm a complete emotional rollercoaster. And it wasn't even worth the short term relief."

1 / 10
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  • Cyb
  • December 18, 2018

"This medication made me moody and gave me bad migraines. I took 10mg non stop for 2 months."

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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