Medroxyprogesterone for Endometriosis User Reviews (Page 2)

• Jamie...
• Taken for 5 to 10 years
• October 29, 2017

Depo Provera (medroxyprogesterone) "DO NOT TAKE THIS DRUG!!! From 1999-2005 I was on depo for birth control. Being young I thought this was the easiest solution and a better alternative to the pill everyday. I injection every 3 months. Sounds great right. Well, in 2005 Pfizer legally had to put a black label warning on their product warning that it may cause osteoporosis. Fast forward to today and I am now diagnosed with MS, there have been claims and speculation about Depo that it’s linked to neurological problems. I am 36 years old and in the next year or so I will have to remove all my teeth and get dentures because there is so much bone density loss in my mouth. Two months ago I had surgery for endometriosis. Osteoporosis testing tomorrow, this drug is not the solution."

• kateeee
• Taken for 1 to 2 years
• November 17, 2015

Depo Provera (medroxyprogesterone) "I've been on depo for almost two years now and have not had a period since i got the injection. i no longer have the debilitating cramps that i would get each month which is a godsend. after i'm first given the shot, i have about 5-7 days of being a little more emotional than usual but it's usually due to my hormones being balanced and changing a little, but it just means a bit of crying and basically how i used to be emotionally before a period. i have noticed that some nights i wake up with a really extreme cramp out of nowhere, but i believe that that might be an issue that's more to due with my hormone levels etc. either way, depo has definitely spared me from weeks spent in bed because of the painful cramps!"

• Anonymous
• Taken for 1 to 6 months
• October 14, 2019

Depo Provera (medroxyprogesterone) "If you ever start to have a period while on depo all you have to do is take 1 month of birth control pills and it will put you back on track. My obgyn let me know this when I told her about my friends experience. She got the depo and had a period for weeks, but a pack of birth control pills fixes it. Just in case y'all never been told this."

• Melly...
• Taken for 2 to 5 years
• January 3, 2013

Depo Provera (medroxyprogesterone) "On Depo for approximately 10 yrs go. No problems or side-effects. No period for 3 yrs-HEAVEN! Got off of it. Doctor said since I had no bleeding last time would be okay to do again. Got shot a month ago-the week I was supposed to start. First week was great. No bleeding but have had continual spotting every day since (3wks). Hopefully it will stop soon. "

• darla...
• July 16, 2015

Provera (medroxyprogesterone) "I took Provera pills daily to stop my periods to kill the monthly pain. I chose pills over the shot so I could have control of deciding when/if I wanted to stop. I took the pills for 6 months. The first month I had lots of breakthrough bleeding - basically I was slowly bleeding for a few weeks. After that I had no period, no spotting, no cramps - that part was FANTASTIC! However, for me the side effects were severe and unlivable. I had insomnia (waking in the night) every night. I had night sweats every night. I gained a little weight. I had extreme vaginal dryness/painful intercourse which was a first ever for me. My sex drive was non-existent and my acne and facial hair (PCOS) got much worse."

• Salem
• Taken for 1 to 2 years
• June 25, 2020

Depo Provera (medroxyprogesterone) "DON'T GET ON DEPO-PROVERA. As someone who has struggled with endometriosis for about 10 years, it is nice not having a period...BUT I gained 40 FORTY pounds in 3 months. I was about 90 pounds and was excited when the lady told me average about 10 pounds are gained. I am 130 now and I have had to buy a new wardrobe. I suffered from an eating disorder when I was in high school, now graduated from college and recovered, I am starting to hate myself again. Not worth it."

• Anonymous
• September 26, 2011

Depo-subQ provera 104 (medroxyprogesterone) "I've only taken one shot, it has been somewhat of a last ditch effort to provide some pain relief from endometriosis and polycystic ovaries. The first month was great, no pain and very little spotting. The second month has been horrible, I had a period for 2 1/2 weeks and the other 1 1/2 I had spotting along with horrible (at times) pain that even Lortab won't fully control. Doctor gave me estrogen to stop bleeding and that took a week. As of now I am not taking another shot. I told my husband that I can feel this bad for free. If this third month goes okay I may reconsider. I've tried everything and its bad...looks like hysterectomy is next step."

• Anonymous
• Taken for 5 to 10 years
• July 4, 2019

Depo Provera (medroxyprogesterone) "I'm 51 ive been on the depo for 9 years , the doc advised me to come of it 18 months ago, so I thought well I must of gone through the menopause by now. So anyway last week my breasts were so tender and extremely sore now this week my periods have returned and oh boy they returned with a passion. I'm bleeding like there's not tomorrow. I'm in excruciating pain 24/7 so I'm off to docs this morning to see if they can help. I've been scared to leave the house as I'm bleeding that much , TBH I want to go back on depo I've never had a problem with it"

• An...
• December 22, 2016

Depo Provera (medroxyprogesterone) "This has been a nightmare. I got the shot to ease pelvic pain my provider suspected was due to endometriosis. At first, I felt like I had the flu for a week or two. Almost exactly a month after getting the shot, I started getting a lot of spotting, and had to wear a pad constantly. After a week of spotting, it became a full-blown, heavy period, and my pelvic pain came back worse than ever before along with severe cramps, muscle aches, and even trouble using the bathroom because of the pain. The pain is far worse at night. I can't sleep. Ibuprofen and heat packs no longer help. It's been three weeks. My doctor isn't sure what to do, and others I've talked to said it took several months for the pain from the depo shot to go away. I'm in agony."

• Loune
• June 29, 2017

Depo Provera (medroxyprogesterone) "I recently tried depo provera for my endo, and it worked great for my heavy periods and also the pain. I barely have any flare ups like before. But my hormones are going crazy or I'm going crazy. I'm irritable all the time and I get so mad over nothing. Wondering whats worse to go through pain or the damn moods swings....."

• Niki
• Taken for 6 months to 1 year
• August 1, 2020

Depo-subQ provera 104 (medroxyprogesterone) "I have been having the depo injection as I have endometriosis. It has worked wonders for me, after the first 2 injections I was spotting a lot, but after the third it stopped my periods completely- which were so heavy and painful. The only down sides are when I first get the injection I am really grumpy for the first few weeks. My sex drive is no where near as high as it used to be and I have gained weight, which the doctors tell you will only happen if you eat more. I find this not to be true, I have been exercising more than I ever have and eat so healthy all of the time. No matter what I am doing I can’t seem to loose the weight."

• Rocky...
• December 2, 2015

Depo Provera (medroxyprogesterone) "Do not get this shot! It tried to ruin my life. Heavy sporadic bleeding, mood swings, depression, headaches, body aches, NO sex drive, terrible cramps, I have little/no emotion for almost everything. I only had 2 shots. I just want to get back to my normal :("

• Anonymous
• October 1, 2011

Depo-subQ provera 104 (medroxyprogesterone) "I've had endometriosis for over 20 years and have had about enough of the pain and the accompanying anemia from blood loss. In the last 5 years my blood loss from the endometriosis has increased tenfold and I have developed severe iron deficiency anemia. My OB/GYN and I decided to try Depo again (last time was in the early 90s) and I had my first shot in July of 2011. August was HEAVEN! No period and my iron levels tested almost normal. I was human again! Now it's September and I have had a "period" (in quotes, because it's more like a normal woman's period) for over 15 days and I feel like I have been hit by a Mac truck. No endometriosis pain, but my iron levels are so low from bleeding that all I can do is sleep. When it works, it's fantastic."

• Scarl...
• November 7, 2013

Depo Provera (medroxyprogesterone) "When I was 7 I started puberty, I started my periods and all the other signs of becoming a "young woman" and I have been having pain since then on, I've had 2 operations, abnormal periods and extensive ones that have lasted 8 weeks and 21 weeks. I'm 18 and have I've been on this injection for nearly 2 months and I've had nothing but pain, I'm heavier on my period than I've ever been and I'm constantly tired, moody, emotional and sick. I can't hold a meal down and I've lost 2 stone because of this and am now classed as underweight. I can't even hold anti-sickness tablets down. I was told to continue to take the pill and then during my break I shouldn't get my period, but I have and they've been causing that much pain can't even walk properly"

• Beyond...
• November 7, 2009

Depo Provera (medroxyprogesterone) "I've been on the Depo-Provera injection since the 1994 inception of off-label use for Endometriosis. For the last few years I've started having some side effects over the two - four weeks prior to each injection including severe fatigue and hot flashes. I'll take those side effects any day compared to how I lived when my "Endo" ruled my day to day life. I've been pain free for years as a result of the 15 years of Depo injections. Other side effects? I guess we will see."

• Kdrag...
• September 28, 2019

Depo Provera (medroxyprogesterone) "This is a HORRIBLE drug. I have a blood clotting disorder, I was prescribed Depo-provera because it was suspected that I had endometriosis. The GYN who prescribed Depo said it would "absolutely cure" the endometriosis IF I had it. We still don't know for sure because the GYN refused to do a laparoscopy. I told the doctor I cannot take hormonal birth control due to my blood clotting disorder and my previous history of DVTs. She insisted Depo was "safe" and does not cause blood clots This is an absolute lie. Within a week of taking the shot. I was in the emergency room with multiple blood clots in my leg. I haven't had an issue with blood clots for 12 years. I'm given this shot and within a week, I have a leg full of blood clots. Sadly, the GYN who prescribed Depo in the first place refused to listen and flat-out denied the Depo caused my blood clots, regardless of all the medical research to the contrary. PLEASE! If you have a clotting disorder or a history of blood clots DON'T TAKE THIS SHOT"

• Never...
• Taken for 1 to 6 months
• May 28, 2020

Depo Provera (medroxyprogesterone) "I cannot explain how bad the depo-provera is. I got this shot once in Sept. 2019 and am still having horrible issues from it and it is now end of May 2020. While on the shot, I bled every single day until Dec when I had a huge bleed out. Since Dec I have been bloated everyday. Doctors now think I have an ovarian cyst that was caused by Depo. Also I have been extremely moody since Sept! My moods and anxiety are so up and down. Never had these issues before. Another terrible side effect is my skin. My skin is extremely oily and I believe this issue was caused by Depo. I've been through tons of shampoos and nothing will solve my oily scalp/skin issue caused by this horrible drug. I'm shocked the side effects have lasted this long. I'm not sure when they will go away. But this drug has cost me hundreds if not thousands in medical bills. Very aggravated. This should not be given to women. Skip the depo please unless you want to deal with all of this!"

• RayRay
• January 26, 2020

Depo Provera (medroxyprogesterone) "I was put on the Depo shot a year ago to help treat my extremely painful periods. It stopped my menstrual so for year I've been able to avoid the terrible pain I was in every month. However, the side effects have been awful. My whole face is covered in painful acne and I didn't have this problem before the shot, I've experienced terrible headaches, I've spotted the whole year I've been on it and had other discharge as well, my anxiety is through the roof and it has worsened my depression. My advice is stay far away from the shot if you can avoid it. I can say its been nice not having the terrible pain endro was causing me every month but the other side effects are almost just as bad. I just had my last shot and will never take it again."

• CokoP...
• Taken for 6 months to 1 year
• February 3, 2017

Depo Provera (medroxyprogesterone) "Suffered with super heavy, painful periods for YEARS. Was finally diagnosed with Endometriosis and an ovarian cyst 9 months ago. Absolutely NO cramping after 2nd shot, no more periods, and I'd probably rate this a 10 if it wasn't for the weight gain (not massive, but still . . . ) and low sex drive. Never had an issue with naturally occurring lubrication (if that's what you want to call it) but I do now. And I don't have orgasms like I used to. Worth it? Definitely YES, because like I said, no more menstrual pain AND I don't have to buy tampons anymore when I was used to using super plus size ones at least 6-10 times a day. FYI my insurance wouldn't cover it for a medical condition, but DOES cover it for birth control. Go figure."

• Breeze
• Taken for 1 to 2 years
• November 7, 2018

Depo Provera (medroxyprogesterone) "This shot has made me pretty much pain free and I couldn't be happier. It's also pretty great to not get a period anymore (except for some infrequent spotting). I suffered horribly for 13 years with lower abdominal pain. My doctor and I decided to try this to see if my pain was endometrial. I didn't want to go through another laparoscopy (where they found adhesions, but wouldn't say it was because of endometriosis). I'm about 90% pain free after a year of taking this medication. I say 90% because once in a while (typically if I'm going to spot), I have pain, but it's tolerable now, not like it was before. I'm really thankful for this medication. It's given me a great deal of my life back."

• Jano
• Taken for 1 to 6 months
• November 29, 2019

Depo Provera (medroxyprogesterone) "Please do NOT take Depo if you have anxiety. If you already have anxiety, Depo increases your anxiety to an unbelievable extent and it becomes unbearable. My hair was falling out in big clumps. I had stomach issues for three months and lost a significant amount of weight. After meeting with a new gynecologist, my therapist, and dermatologist we all figured out that it was because of Depo. It also did NOT help with my Endo. I had a 19 day heavy period, the worst cramps, and brown discharge for 49 days (not an exaggeration). Please be careful."

• Anonymous
• September 14, 2009

Depo Provera (medroxyprogesterone) "I had been on Depo for 5 years as a birth control method. I knew that there was always something wrong with doctors. They just told me that I had bad period cramping and basically to deal with it. It is only now after I stopped the Depo, to try and fall pregnant, that doctors have now tested me for and confirmed that I have endometriosis. The pain that I am in now is crazy, but I am not going to go back on it in the hope that I may just by chance perhaps fall pregnant! It worked really well for me when I was on it though, had no cramping as my periods had stopped completely."

• 64978...
• March 8, 2010

Depo Provera (medroxyprogesterone) "I guess the only advice I have is for everyone on or considering this medication to weigh the pros and cons. I've been on the shot for 5 years now, and have recently had to have my frequency increased to every 8 weeks, versus the normal 12. My cycle completely stopped 2 weeks after my first injection. I have only had a few breakthrough bleeds, which have been treated with anti-inflammatory drugs or and additional dose of the Depo. I have had some side effects. I've gained about 15-20 pounds, but it showed up "in the right places". I get very moody occasionally, but I'll take that over amenorrhea any day."

• Angel...
• September 26, 2009

Depo Provera (medroxyprogesterone) "I have taken Depo-Provera now for 4 years. It took care of the severe pain, cramping, and hot flashes. I have also not had a period since or even spotted. Although it has helped positively with these things there are negative side effects. I gain and plateaued at a whopping 57 pounds. I gained the first 25 pounds in the first 3 months, keeping in mind that I had not changed eating habits or exercise, and now I have stretch marks from the rapid weight gain. All I can say is to try it yourself, this is just how it affected me."

• sarah
• June 23, 2018

Depo Provera (medroxyprogesterone) "I HATE this shot, it ruined my life. I had very severe side affects that started the day after I got the shot, and have not stopped. My old provider refused to admit that my pain was due to the shot. I have constant cramping, constant bleeding, migraines, my hair is falling out, my depression is worse than ever, increased anxiety, insomnia, muscle soreness, joint pain and mood swings. I was told that this shot would stop my period, it did not, it just made my period last for 10 months, and it is still going. I will never get this shot again, and I do not recommend this shot for anyone."