Lumateperone for Bipolar Disorder User Reviews (Page 5)

• tep...
• Taken for 6 months to 1 year
• March 14, 2023

Lumateperone "After having horrible nausea with lithium, my doctor switched me to Caplyta. I felt my highs and lows to be less dramatic. My biggest issue was the extremely dry mouth, but besides that for me, I didn't have huge issues with the other known side effects."

• ser...
• Taken for 1 to 6 months
• September 24, 2023

Lumateperone "I'm terrible at taking my medications regularly, Caplyta has been no exception. I take 1 at night and sleep like a baby for about 8 to 10 hours. I get no negative side effects at all. They are expensive, but if they work with no negative effects, to me that's priceless. I take it erratically, but it has boosted my mood a little, probably due to more sleep. It's also calmed me a little, I'm less moody, and have fewer mood swings. I'm slower to react, and I even think before I speak on occasion. The pills are easy to swallow, and it takes about 30 minutes to kick in."

• jus...
• Taken for less than 1 month
• November 30, 2022

Lumateperone "I'm taking Caplyta for bipolar depression. I am 3 weeks in, and the side effects are kind of rough. Super dry mouth and nausea, constant yawning, and like a shaky feeling. I can tell it's working, but now I'm just noticing the side effects."

• Anonymous
• Taken for 1 to 2 years
• May 26, 2023

Lumateperone "Caplyta comes in 20 mg pills. I agree with all of the above reviews that my initial experience with the drug replicated the feeling of super icy or extremely hot sensitivity. I talked to my psychiatrist about this, and he recommended opening up the capsule and taking a micro dose of the pill on my tongue or putting it in applesauce. That cuts down on those side effects. It works really well as an anti-depressant for bipolar and is one of the few drugs on the market that does that. And just as a side note, if you have bipolar depression, you shouldn't be taking anything in the serotonin class because bipolar depression has nothing to do with dysregulation of serotonin. It will only make you more dysregulated over time. Caplyta is a D1, D2, and D4 antagonist, all of which have been shown to be implicated in bipolar depression."

• Hap...
• Taken for 6 months to 1 year
• January 22, 2023

Lumateperone "I suffer from depression, possibly unipolar, possibly (what my current psychiatrist thinks) bipolar II. I've been on Caplyta 42 mg for 11 months. The first few weeks, it seemed miraculous. I'd been suicidal due to lack of sleep; suddenly, I was sleeping 7-8 hours a night, and, what's more, in a good mood all day, even in the early mornings and the evenings. There was a bit of grogginess, but it wasn't bad. But gradually over the months, the side effects increased: the grogginess got worse, I seemed cold all the time, and I became easily confused in the evenings. And much of the positive effect on my mood went away; though my grogginess was greater-in fact, it was the worst grogginess I'd experienced in my life-I was sleeping less. Part of the worsening side effects may be a result of my deteriorating kidneys (I'm in stage 3 kidney disease). Now, at 11 months, the grogginess is slightly better, the chills are mostly gone, I'm sleeping 5-6 hours. My mood is usually good if I can wake up."

• Rd9...
• Taken for 1 to 6 months
• August 29, 2022

Lumateperone "I have been on Caplyta 42 mg for about 3 to 4 months. At first, the only side effect I had was when I woke up in the morning. I took it at night, I would feel extremely tired but couldn't nap. It did work for my hallucinations at first, but I always build a resistance to all of the antipsychotics that I've taken. So my hallucinations are back, but now are worse than before. I also noticed that I talk way more than I have in the past. I usually don't talk much. I'm gonna rate it higher than low because it does work, I just am resistant to treatment."

• Lor...
• Taken for 1 to 2 years
• January 5, 2025

Lumateperone "I've been taking this drug for a while now. It's been at least a couple of years now. And I've noticed it doesn't make me gain weight, which is a big plus for me and others as well who are having to use this prescription drug for whatever they are in need of it for. In my case, I'm bipolar 1. And what I was told by my Dr. is that I would have issues with going to the restroom, number 2, which I've had problems with before taking it. I found out that on my dad's side of the family, cancer runs in the bowels, and he had an issue there a while back. So this makes me very concerned about if I should even be taking this medication."

• Sue...
• Taken for less than 1 month
• February 10, 2022

"I only took 1 pill and became dizzy and couldn’t walk right. I went to bed feeling weird and had a headache that kept me up all night. I was nauseous as well. Had to leave work to come home and sleep it off. Never again. Good luck, maybe it will work for you."

• Jfh...
• Taken for less than 1 month
• December 25, 2023

Lumateperone "Within a couple of weeks of starting, my depression had gone from severe to moderate-severe. It was a noticeable improvement and was very welcome. I did not notice any side effects that I usually get with atypical antipsychotics. One of the few psych meds I've been on that I'd recommend!"

• jlm...
• Taken for 1 to 6 months
• October 8, 2022

"I've been in the entire battery of atypicals as well as Haldol and Thorazine, which did absolutely nothing to me. All the mania meds in the rotation, as well as every antidepressant most people have heard of, from Prozac to when Cymbalta was the fad. Prozac worked in combination with Zyprexa, but it had devastatingly strong side effects. All the other combinations did nothing worthwhile, or the ones that stabilized me caused me to gain 200 lbs over the years and would cause me to be unable to stay awake at work, and I'm a licensed medical professional. I was highly skeptical when a clinic psychiatrist wanted to try another drug du jour after being completely off medications for 9 months for the first time in a decade. I had lost 2 great jobs in 3 months because I couldn't keep my bipolar butt together with 100% compliance with Latuda. Nothing seems to bother me after 12 weeks-well, things-but I have a new take: why not use my negative feelings as learning tools? Caplyta makes this practice more palatable."

• Anonymous
• Taken for less than 1 month
• February 9, 2022

Lumateperone "I started this for bipolar 1 on 2/5/22. At first, I couldn't sleep. Day 4 was much better. I feel more like my old self now. I have had no side effects, and maybe won't have any."

• Yol...
• Taken for 1 to 6 months
• August 8, 2024

Lumateperone "My experience has been good. I am very stable, and I don't have any weight gain or sedation."

• Cap...
• March 10, 2022

Lumateperone "Horrible! Can’t wait for the effects to go away."

• blu...
• Taken for 1 to 6 months
• July 7, 2024

Lumateperone "Excellent medication. I tried antidepressants all throughout the nineties up until now. They never really worked for me. Caplyta helps with my hyperactivity, anxiety, and depression symptoms."

• tra...
• Taken for 1 to 6 months
• May 26, 2024

Lumateperone "This medicine is the best bipolar medicine I've been on. Taking this medicine has leveled me out. Other medications would have me so agitated. I love this medicine."

• lex...
• Taken for less than 1 month
• May 23, 2022

Lumateperone "Absolutely horrible. I threw up, my hands and feet started swelling up and felt like they were on fire, I had a fever of 100, and I went in and out of consciousness."

• Bip...
• Taken for less than 1 month
• January 29, 2022

Lumateperone "Has anyone taken this for bipolar? Thinking about giving it a try."

• Anonymous
• Taken for less than 1 month
• April 16, 2022

Lumateperone "First day on Caplyta. Little to no side effects compared to half a dozen others I’ve tried. So far, so good."

• Lis...
• Taken for 1 to 6 months
• May 30, 2023

Lumateperone "Made me more depressed, very tired, and unfocused. Not a good combo for a person with bipolar and ADHD. I tried it for a month before giving up."

• God...
• Taken for less than 1 month
• October 23, 2023

Lumateperone "Switched from Abilify to Caplyta and so far it's been a miracle drug. I've lost 11 pounds in a little over 2 weeks with no side effects to speak of. I'm excited to see its full potential soon."

• Anonymous
• Taken for less than 1 month
• September 18, 2022

Lumateperone "Make me feel super tired and hungover the next day, terrible headache, and body temp fluctuations."

• Jay...
• Taken for 1 to 6 months
• July 7, 2023

Lumateperone "Help my depression go away and stay away, overall no side effects, seems to have helped me tremendously!!!"

• Anonymous
• May 13, 2023

Lumateperone "Caplyta helped my bipolar and my moods. After 2 months, though, I started to get neck pain. I took it for another month and then finally quit taking it. I'm still having neck pain."

• Joh...
• Taken for 1 to 6 months
• May 19, 2023

Lumateperone "Didn't feel any different and was nowhere near as effective as lithium. I experienced no side effects or any benefits."

• Suz...
• Taken for less than 1 month
• July 29, 2024

Lumateperone "Very, very tired. Slurred speech, diarrhea, dry mouth, headaches."