Lubiprostone for Irritable Bowel Syndrome with Constipation User Reviews (Page 3)

• OTT...
• Taken for 1 to 6 months
• November 22, 2016

Lubiprostone "I started on just 8 mcg and noticed no change at all in a month, so my GI decided to up it to 24, I believe. I'm on a lot of medication for chronic pain and tumor damage to my brain, so juggling all my meds, it took me almost a month to figure out the higher dosage was causing me to throw up every morning. I wake up and take all my morning pills, so obviously my stomach is kind of empty, and 40 minutes later I'm vomiting with little warning. I thought it was associated with another brain tumor, as when I took the pill again at 6, I didn't get sick, but by then I had a meal in me. It has helped somewhat with my bowels, but I'm still on Miralax and stool softener, and the copay is pretty high, so with all considered and how lousy the side effects are."

• Ano...
• Taken for 2 to 5 years
• December 4, 2017

Lubiprostone "I’ve been on Amitiza 24 mg for 2 years. At first, it was 2 pills a day, but the side effects were horrible. The doctor then reduced it to 1 pill a day, and at first, it worked great. But in the last year, I’ve had constant, explosive diarrhea with constant stomach pains. Last Saturday was the last straw, and I stopped taking it. Now I’m a little constipated and have some stomach pain, but no explosive diarrhea. The medicine they give you to stop the diarrhea, while on Amitiza, constipates me for a week and makes me feel extremely uncomfortable and full. I’ll take IBS constipation over that any day."

• Ano...
• Taken for 1 to 6 months
• June 29, 2025

"After many years of treating IBS-C or slow motility problems with a regimen that included Miralax, Benefiber, and Magnesium, my gut motility suddenly got very slow, and each bowel movement was way too firm and took too long to pass. I ripped my anus a little, started using stool softener, and finally called my primary. She prescribed lubiprostone because it is a covered med, where Linzess is not. It was effective but did cause nausea and general tiredness. In the meantime, she ordered a blood test, and we found that my thyroid medicine wasn’t keeping up. An increase in that prescription has allowed me to slowly back off of Amtiza (generic) to once a week. I never stopped the M+B+Mg regimen. I did find, like others, that taking it near bedtime was the best way to avoid the nausea. Taking it with meals wasn’t enough. I had to pay about $1 per pill for this."

• jac...
• Taken for 1 to 2 years
• January 23, 2014

Lubiprostone "Bloating was my biggest problem. I felt so bloated, I looked pregnant! Nothing helped... and I tried them all until I tried and stayed with Amitiza. It was and is worth the expense."

• Anonymous
• March 15, 2009

Lubiprostone "Caused breathing problems."

• Tha...
• Taken for 2 to 5 years
• December 13, 2022

Lubiprostone "Amitiza allows me to feel amazing and have normal bowel movements and no more crazy bloating. God bless. I’ve been taking it for 5 years. I have IBS and had SIBO."

• lin...
• Taken for 1 to 2 years
• April 12, 2018

Lubiprostone "I have IBS with constipation. I take Amitiza twice a day. I lost 52 pounds in one year. It has been wonderful! No bloating anymore."

• Anonymous
• Taken for 1 to 6 months
• August 17, 2012

Lubiprostone "I love this medication. Nothing else has helped me with chronic constipation for my gastric paresis and irritable bowel."

• tan...
• July 4, 2010

Lubiprostone "This is really working for me. I am taking 24 mg once a day. I have had no side effects at all."

• Anonymous
• Taken for less than 1 month
• November 9, 2012

Lubiprostone "This is my second attempt with Amitiza (this time at the lower dose). Unbearably nauseated once again on top of the constipation and abdominal cramping. Does not work for me at all."

• Anonymous
• August 2, 2009

Lubiprostone "Felt normal in 24 hours."

• Anonymous
• October 12, 2008

Lubiprostone "The side effect of slight nausea is worth the outcome."

• Ted...
• Taken for less than 1 month
• January 11, 2021

Lubiprostone "I've been taking Amitiza 24 mg twice a day for a week. I'm feeling much better with my IBS. I'm also taking Lexapro 20 mg, it helps a lot with IBS pain."

• rgc...
• October 22, 2009

Lubiprostone "Has not helped me, and the side effects are rough."

• elj...
• Taken for less than 1 month
• October 8, 2019

Lubiprostone "I could not leave the house after breakfast, as the Amitiza was making me poop small bits of poo every 30 minutes from breakfast to early afternoon. Who can live that way?"

• Ibs...
• Taken for 1 to 6 months
• February 21, 2016

Lubiprostone "This drug had no effect on me except for a very strange taste in my mouth. I stopped taking this after 3 weeks. I was on a low dose. Will go to a specialist soon to discuss."

• Dee...
• Taken for less than 1 month
• March 12, 2019

Lubiprostone "Day 4 on Amitiza and still nothing. No cramps. So much for the miracle drug. Called doc's office and I'm still waiting for a response."

• Bro...
• Taken for 1 to 6 months
• July 31, 2020

Lubiprostone "I take 24 mcg Amitiza for IBS, and it has been a nightmare. I just end up with watery diarrhea. It is awful. I'm begging for a lower dose, or I'm going back to Miralax."

• Jud...
• Taken for less than 1 month
• March 30, 2019

Lubiprostone "I did not get nauseous or have any bad side effects. This pill just didn't work at all for my IBS."

• Anonymous
• November 17, 2021

Lubiprostone "Amitiza was the only thing I ever took that helped me. But my Humana insurance will not let me have it."

• Aca...
• July 13, 2016

Lubiprostone "Amitiza is the best if you have IBS!"

• Cin...
• September 30, 2018

Lubiprostone "It is horrible. I have nauseousness, vomiting, and it doesn't work."

• 133...
• Taken for 6 months to 1 year
• February 20, 2024

"Had very good results using lubiprostone. Would highly recommend it."

• Hea...
• July 21, 2021

Lubiprostone "I have been now on it for two weeks. Hasn't done a thing!"