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Lofexidine and Tremors: What Users Say

Brand names: Lucemyra

Tremors: mentioned by 8 users (16.0%)

Based on user experiences from 50 Lofexidine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 18.0%
tremors 16.0%
dry mouth 12.0%
tiredness 12.0%
blood pressure 10.0%
drowsiness 10.0%
loss of appetite 8.0%
fainting 6.0%
fatigue 6.0%
high blood pressure 6.0%

Reviews for Lofexidine

Commonly mentioned side effects
  • Acc...
  • Taken for 5 to 10 years
  • November 16, 2018

For Opiate Withdrawal "Was on Fentanyl patch for over 8 years from a near-fatal accident. Decided to stop Fentanyl with Lucemyra. First 2 days were wonderful. I had the best sleep of my life. I was very sleepy and dizzy. The 3rd day, I was more awake and doing fine. This continued until the 9th day. My normally low blood pressure began to rise. On the 11th day after starting the drug, I had vomiting and such a severe headache that my husband took me to the ER. My blood pressure at that time was 195/95. I had a head CAT scan and was given non-opioid meds to relieve pain. I did not sleep at all for 38 hours. Now on day 13, I am not having any head pain, but am experiencing severe abdominal pain and diarrhea. I am very shaky. I have no real appetite, food tastes bad, and my stomach is so painful. Hoping things get better."

2 / 10
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92 Report
  • Mar...
  • Taken for less than 1 month
  • February 12, 2019

For Opiate Withdrawal "Lucemyra is a nightmare!!! PAID $2,000 for the ABOVE!!! FAINTING, SHAKING, NO SLEEP, NO APPETITE, DEHYDRATED, SORES AROUND MOUTH & IN THROAT, BECAME A MONSTER ON IT, NEEDED 24/7 HELP, NO WORK, NO PERSONAL HYGIENE ON OWN, LOST MY LIFE FOR 9 PLUS DAYS & THERE ARE MORE SYMPTOMS... A DEADLY DRUG!!!"

1 / 10
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65 Report
  • Beh...
  • Taken for less than 1 month
  • April 10, 2020

For Opiate Withdrawal "I was on Zubsolv 8.6 x2 a day, which I definitely abused and was taking 6-9 a day. Due to another medical condition, doctors needed me off these subs cold turkey. Being on such a high dose, I was scared. After taking the first dose of 3 pills, sweats and aches stopped. The second dose of 3 pills knocked me out for hours, then I knew I couldn’t continue taking the full dose. Day 2, I only took 1 pill twice, and it again stopped the sweats, aches, and I never ever felt any shakiness, pretty miraculous in my opinion. I went a week or two like this and did take 2 or 3 pills later PRN. This was easily manageable compared to the actual nightmare withdrawals are. I never got close to taking the full dose of 3 pills 4x a day, and I didn’t get many side effects. I will say though, my mood was terrible, especially before I took the first dose of the day, I got into nasty fights. This drug helps physical symptoms, not so much mental ones. It can help with anxiety, but I ended up getting anxiety meds after."

9 / 10
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38 Report

Frequently asked questions

  • Not...
  • Taken for less than 1 month
  • July 3, 2019

For Opiate Withdrawal "I took the full dosage for 3 days (3 pills/4x) and tapered the last 2 (day 4, 2 pills/2x and day 5, 1 pill/2x) because of how much I needed to be off this. I had been taking between 20-60 mg of Percocet for over a year for back surgery to give reference. Please make sure that you do the following things before you begin taking this medication. #1) The medication has an app called LUminate. #2) Make sure you have a blood pressure reader of some sort. #3) Have someone to support you or have a support group online. #5) Drink plenty of fluids with electrolytes. Get sugar-free gum and hard candy to suck on. Follow the GERD diet. #4) Create a COW score with your doctor to create a dosing and taper that is right for you. My symptoms were the following: opiate withdrawal - arm spasms and twitching, restless legs, weakness. Lucemyra: drowsiness, low blood pressure, major cotton mouth, insomnia."

3 / 10
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44 Report
  • Chr...
  • Taken for less than 1 month
  • December 1, 2023

For Opiate Withdrawal "This medication has helped me gain back my freedom. I have chronic pain and was prescribed Roxys for it. My husband got a herniated disc and couldn't get help, so we bought what we thought were Roxys off the street and ended up with a 3-year fentanyl addiction. I tried Suboxone several times and went into precipitated withdrawal. I couldn't get past day 2 of withdrawals without relapsing. I went to a detox and was given Lucemyra, 2 pills every 8 hours, 4 times a day. I didn't have the shakes, terrible sweating, tremors, runny eyes, and nose. I basically was left with digestive issues, which I used Imodium and Zofran to help with that. On days 3 and 4, I felt a little bit of the skin crawls at hour 5 while waiting to take my next dose of Lucemyra. It did lower my blood pressure, therefore making me sleepy. I was able to make it through detox with no Suboxone and get clean. This medication should be available to people with any opioid addiction, especially fentanyl, heroin, and Suboxone, to stop."

9 / 10
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8 Report

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  • Chr...
  • Taken for less than 1 month
  • December 1, 2023

For Opiate Withdrawal "This medication has helped me gain back my freedom. I have chronic pain and was prescribed Roxys for it. My husband got a herniated disc and couldn't get help, so we bought what we thought were Roxys off the street and ended up with a 3-year fentanyl addiction. I tried Suboxone several times and went into precipitated withdrawal. I couldn't get past day 2 of withdrawals without relapsing. I went to a detox and was given Lucemyra, 2 pills every 8 hours, 4 times a day. I didn't have the shakes, terrible sweating, tremors, runny eyes, and nose. I basically was left with digestive issues, which I used Imodium and Zofran to help with that. On days 3 and 4, I felt a little bit of the skin crawls at hour 5 while waiting to take my next dose of Lucemyra. It did lower my blood pressure, therefore making me sleepy. I was able to make it through detox with no Suboxone and get clean. This medication should be available to people with any opioid addiction, especially fentanyl, heroin, and Suboxone, to stop."

9 / 10
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8 Report
  • Anonymous
  • May 6, 2021

For Opiate Withdrawal "Went to detox for Suboxone and Valium and vodka. Did vodka detox with Ativan. Then buprenorphine taper. Was fine. No shakes or nothing. Started Lucemyra, guessing doctors get a portion of the gigantic cost of the drug. Left me just hitting the floor if I tried to stand up. Counselors witnessed, nurses made aware but kept giving it. Once I got out and stopped, can’t afford $2000. Shakes hit, haven’t eaten in 3 days. Tremors from head to toe. Can’t stand without nearly passing out. Not in a good way. Avoid at all costs. Refuse it."

1 / 10
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9 Report
  • Anonymous
  • May 6, 2021

For Opiate Withdrawal "Went to detox for Suboxone and Valium and vodka. Did vodka detox with Ativan. Then buprenorphine taper. Was fine. No shakes or nothing. Started Lucemyra, guessing doctors get a portion of the gigantic cost of the drug. Left me just hitting the floor if I tried to stand up. Counselors witnessed, nurses made aware but kept giving it. Once I got out and stopped, can’t afford $2000. Shakes hit, haven’t eaten in 3 days. Tremors from head to toe. Can’t stand without nearly passing out. Not in a good way. Avoid at all costs. Refuse it."

1 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.