Lofexidine and Drowsiness: What Users Say

• Acc...
• Taken for 5 to 10 years
• November 16, 2018

Lofexidine for Opiate Withdrawal "Was on Fentanyl patch for over 8 years from a near-fatal accident. Decided to stop Fentanyl with Lucemyra. First 2 days were wonderful. I had the best sleep of my life. I was very sleepy and dizzy. The 3rd day, I was more awake and doing fine. This continued until the 9th day. My normally low blood pressure began to rise. On the 11th day after starting the drug, I had vomiting and such a severe headache that my husband took me to the ER. My blood pressure at that time was 195/95. I had a head CAT scan and was given non-opioid meds to relieve pain. I did not sleep at all for 38 hours. Now on day 13, I am not having any head pain, but am experiencing severe abdominal pain and diarrhea. I am very shaky. I have no real appetite, food tastes bad, and my stomach is so painful. Hoping things get better."

• Not...
• Taken for less than 1 month
• July 3, 2019

Lofexidine for Opiate Withdrawal "I took the full dosage for 3 days (3 pills/4x) and tapered the last 2 (day 4, 2 pills/2x and day 5, 1 pill/2x) because of how much I needed to be off this. I had been taking between 20-60 mg of Percocet for over a year for back surgery to give reference. Please make sure that you do the following things before you begin taking this medication. #1) The medication has an app called LUminate. #2) Make sure you have a blood pressure reader of some sort. #3) Have someone to support you or have a support group online. #5) Drink plenty of fluids with electrolytes. Get sugar-free gum and hard candy to suck on. Follow the GERD diet. #4) Create a COW score with your doctor to create a dosing and taper that is right for you. My symptoms were the following: opiate withdrawal - arm spasms and twitching, restless legs, weakness. Lucemyra: drowsiness, low blood pressure, major cotton mouth, insomnia."

• Chr...
• Taken for less than 1 month
• December 1, 2023

Lofexidine for Opiate Withdrawal "This medication has helped me gain back my freedom. I have chronic pain and was prescribed Roxys for it. My husband got a herniated disc and couldn't get help, so we bought what we thought were Roxys off the street and ended up with a 3-year fentanyl addiction. I tried Suboxone several times and went into precipitated withdrawal. I couldn't get past day 2 of withdrawals without relapsing. I went to a detox and was given Lucemyra, 2 pills every 8 hours, 4 times a day. I didn't have the shakes, terrible sweating, tremors, runny eyes, and nose. I basically was left with digestive issues, which I used Imodium and Zofran to help with that. On days 3 and 4, I felt a little bit of the skin crawls at hour 5 while waiting to take my next dose of Lucemyra. It did lower my blood pressure, therefore making me sleepy. I was able to make it through detox with no Suboxone and get clean. This medication should be available to people with any opioid addiction, especially fentanyl, heroin, and Suboxone, to stop."

• 505...
• Taken for less than 1 month
• July 3, 2021

Lofexidine for Opiate Withdrawal "I would have to say this medicine is a blessing and a curse. Today is the first day off the medicine, and I feel great. But it wasn’t all roses and sunshine. Extreme dry mouth. Today is the first day I haven’t felt like I ate a bar of deodorant in 6 days. Extreme sleepiness when taking the 3x4. Slept 16 hours the first day. If you have a job, take off a Friday and start it then. That way, you have 3 days to adjust. If you decide to wean off after a few days, make the 3 at night the last one you reduce. I felt good during days 2-5, slowly reducing my dose, but still had to take 3 at night to keep the arm twitches at bay. Have a serious and truthful discussion with your doctor about what a smart dosing plan is for you. There is no reason for someone taking 1/4 of a sub strip to be on the same plan as someone taking 2 8/2 strips a day. I didn’t experience extreme dizziness, just felt a little off. This medicine can help you, but be aware that it is a rough go the first 48-72 hours."

• TBG...
• Taken for less than 1 month
• March 8, 2022

"Lofexidine works great for Tourette syndrome, like clonidine, but with less impact on blood pressure. On a fairly high dose, and it’s effective without making me drowsy. This has caused drowsiness in others, but not me. Really reduces tics."