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Linagliptin and Joint Pain: What Users Say

Brand names: Tradjenta

Joint pain: mentioned by 12 users (14.8%)

Based on user experiences from 81 Linagliptin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

joint pain 14.8%
back pain 12.3%
dizziness 12.3%
headaches 9.9%
tiredness 9.9%
stomach pain 8.6%
weight gain 7.4%
diarrhea 4.9%
itching 4.9%
muscle pain 4.9%

Reviews for Linagliptin

Commonly mentioned side effects
  • Ann...
  • Taken for less than 1 month
  • September 21, 2020

Linagliptin for Type 2 Diabetes "I’ve been on Tradjenta for three weeks. I was on it before but stopped due to side effects. A new doctor insists it has no side effects and is easy to take. I disagree. My anxiety has gone through the roof with frequent anxiety attacks. I get so dizzy, I fall, often. I’m hungry all the time. I was losing about a pound and a half a week. Now I’m gaining again. My blood pressure has gone from 89-90 on top to 166 today. I thought the joint and back pain was from sleeping funny. This med needs to be stopped. I talk to her tomorrow. Praying she stops it. Oh, and my numbers are as high as ever in spite of eating better."

1 / 10
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78 Report
  • Jos...
  • Taken for less than 1 month
  • April 19, 2020

Linagliptin for Type 2 Diabetes "I took Tradjenta for three days. Severe headache, stomach pain, joint and muscle pain, depression! Stay away from this drug, it is very toxic. I am still having issues from it five months after I stopped taking it. It causes nightmares also. It is a horrible drug that I can't imagine how it was ever approved for distribution."

1 / 10
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63 Report
  • 129...
  • Taken for 1 to 6 months
  • December 14, 2016

Linagliptin for Type 2 Diabetes "I have been on Tradjenta for 90 days. I have gained 13 pounds, my daily fasting numbers are up by 20 points, my joints and back ache regularly, I have diarrhea several times a day and I have no energy. Today, I called my doctor with all of these side effects, and he told me to stop the medication and keep track of my daily fasting blood sugar. I wish I could do it on my own, with no drugs!"

2 / 10
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71 Report
  • dky...
  • Taken for 6 months to 1 year
  • September 4, 2015

Linagliptin for Type 2 Diabetes "I was taking Januvia, but my insurance will no longer cover it, so I was then switched to Tradjenta. I take 5 mg Tradjenta with Metformin daily. My blood sugar is not as low or stable as it was with the Januvia, and I am having very bad muscle and joint pain, severe headaches, back pain, and weakness. I never had these symptoms previously, so it must be the Tradjenta. I never associated the problems with this medication until I read an article on it. I will be contacting my doctor regarding this medication."

3 / 10
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58 Report
  • Gre...
  • September 19, 2019

Linagliptin for Type 2 Diabetes "I have type 2 diabetes, and I have been taking Tradjenta for over a year. I also take Tresiba. I switched insurance and had to have a prior authorization for them. I have been off both Tradjenta and Tresiba for a week while waiting for my new insurance to approve. I realize that I no longer have joint pain or stiffness. No lower leg edema or dizziness. I don’t think this drug is the most appropriate for me. I had drug-induced (Metformin) that caused acute/chronic renal failure, so I have to be sure that the medication will not cause further kidney damage."

2 / 10
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26 Report

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  • Squ...
  • October 6, 2017

Linagliptin for Type 2 Diabetes "I have type 2 diabetes and have had severe osteoarthritis for years prior to taking Tradjenta. The one good thing about it is my doctor says it makes you feel fuller, and I'm able to verify this. I'm able to resist sugar cravings easier. However, I must go off this because of severe joint pain and stiffness that is unusual even by my standards. I can't sleep or get out of bed, it's so bad. It's so bad, I'd rather not take it and take the risk of developing kidney failure because it's not worth it."

2 / 10
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27 Report
  • Bob...
  • Taken for 1 to 6 months
  • March 5, 2018

Linagliptin for Type 2 Diabetes "Tradjenta didn't work for me. The side effects were severe for me. I was unable to walk without help, nausea with stomach pain, back pain was extreme, my blood sugars went up 40+, diarrhea, joint pain was terrible. Finally, got off medicine and improved."

1 / 10
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21 Report
  • lcg...
  • Taken for 1 to 6 months
  • October 21, 2020

Linagliptin for Type 2 Diabetes "I have been taking Tradjenta for about 6 months. I have had numerous sinus infections, I'm tired, my joints are so painful, and I've gained weight. I did not think anything of it until I decided to figure out what changed, and this all started after taking Tradjenta. I cannot wait to stop this medication. I am switching to Jardiance, I know that also has side effects, but I am willing to try it out. The constant feeling of having a cold with Tradjenta is not worth it anymore."

3 / 10
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15 Report
  • Mom...
  • Taken for 1 to 6 months
  • November 8, 2020

For Type 2 Diabetes "I have been diabetic type 2 for 7 years. I take metformin and glipizide, but my sugars were off the scale, so I was put on linagliptin 5 mg. My daily sugars are between 4.5 and 7.4. My HbA1c dropped from 78 to 54 in 3 months - it's really doing its job. I have lost about 12 lb in 5 months, but the only side effect that is crippling me is joint pain. My hips don't belong to me, stiff, painful, and sometimes I find it hard to walk. I hope this is helpful."

8 / 10
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4 Report
  • Den...
  • Taken for 1 to 6 months
  • January 12, 2016

Linagliptin for Type 2 Diabetes "Extreme diarrhea with no warning, very rancid and loud belching with no warning, headaches, joint pain, chills, fevers sometimes, weight gain."

1 / 10
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44 Report
  • DAV...
  • February 20, 2019

Linagliptin for Type 2 Diabetes "I took this medication for around 10 days, and the joint pain was so bad I could no longer use my right arm because of the pain in my right elbow. I will look for a different drug."

2 / 10
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22 Report
  • Anonymous
  • Taken for less than 1 month
  • May 30, 2017

Linagliptin for Type 2 Diabetes "Took for three weeks and became totally debilitated with joint pain, swelling of ankles and hands. Some days could not use hands and barely able to walk."

2 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.