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User Reviews for Levomilnacipran

Also known as: Fetzima

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Levomilnacipran.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Major Depressive Disorder 63 reviews 46 medications
   
5.1
Depression 64 reviews 79 medications
   
4.9
Summary of Levomilnacipran reviews 127 reviews 5.0

Reviews for Levomilnacipran

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Fetzima (levomilnacipran) for Depression: "I've taken several different SSRIs and SNRI's. This medication is the worst I have even taken. It makes me feel worse than I felt before I started taking anything at all - sweating, hot flashes, my mouth constantly tastes like I drank salt water, constipated, bloated, nausea, exhausted. You name It. EXTREME RAGE!!!! stay away from this med. it's a scary thing"

   
1.0

Asdf238495 (taken for 1 to 6 months) July 13, 2017

1 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I've tried 20+ meds over the last 30 years to treat depression. I've had wonderful results with Fetzima and Trileptal. I've been on the medication about 18 months now. Some GI issues, some sweating, though not as intense as others have mentioned. As I've increased dosage I definitely experienced rage, but it subsided within a week. I've had an increase in blood pressure, but it was already high & a med adjustment solved it. A weird side effect: I talk a lot more than I did before. I can stop myself, but the tendency is new. I can deal with these side effects. They've not been intense or long lasting. My depression was horrible for 7+ years. I've gone from failed suicide attempts to feeling good again. I'm very grateful for this drug."

   
9.0

SophieIreland (taken for 1 to 2 years) July 5, 2017

1 users found this comment helpful.

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For Major Depressive Disorder: "Was on Fetzima for a week and got Serotonin Syndrome. This is my 5th day off of the med and I am still nauseous, hot, red hot flushed face and chest, body aches and pain. Sweating, chills, goose bumps, constant headache, etc. Ugh, hope it goes away soon, this sucks!!!"

   
1.0

bppeanut (taken for less than 1 month) June 15, 2017

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Fetzima (levomilnacipran) for Depression: "I was surprised to see that there were some reviews that showed it wasn't helping some people. I'm very sorry for that. Depression runs in my family. I've been on over 20 different antidepressants throughout my life. Nothing has ever worked. I don't recall any improvement from anything. I started fetzima about 2 years ago. I felt relief within 1 week. I couldn't believe the difference within 2 weeks. I have experienced some rough times. I've had a few suicide attempts and woke up in ICU 3 times. I'm not trying to say I've had it worse than anyone. I'm just saying that was the place I was in. This was the only med that worked. The only drawback is the cost. It's very expensive without a savings card."

   
10

Anonymous (taken for 2 to 5 years) June 13, 2017

4 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I have had depression most of my life but well controlled. I had a very traumatic experience that totally changed my life. It totally turned my life upside down. My doctor prescribed Fetzima. I this helped to some point. I still don't feel like I can be myself and enjoy life. I have been better on other things."

   
5.0

Cassmar1 (taken for 6 months to 1 year) May 30, 2017

4 users found this comment helpful.

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Fetzima (levomilnacipran) for Depression: "Also wanted to add since I ran out of room on my last post that this medication has also caused me to have SEVERE hot flashes, I'm going through menopause but my hot flashes were not as bad until I started taking fetzima, after I went off of it for 3 months my hot flashes almost vanished, not as severe and not so many and now I've been back on fetzima again for 3 months and HELLO HOT FLASHES, this medication is the worst!!!!!!!!"

   
1.0

ThereseCup (taken for 1 to 2 years) May 30, 2017

6 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I was 120mg. Was great for my mood, but I had several side effects including: increase blood pressure, tachycardia, urinary hesitation, constipation, bloating, stomach pain, dry mouth, nausea, and UTI. My Dr. told me to choose whether I wanted to feel good mentally or physically. Looking for new Dr. I think I deserve both. one without the other is simply existing,and I want to live life happy and healthy."

   
1.0

Mrs. WP May 25, 2017

8 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I've tried damn near every med you can think of. I have MDD, GAD, PTSD, ADHD..wellbutrin stopped working after 3 yrs, and I don't do well on SSRIs (fetzima is SNRI). So I said , everyone is built different, so trial and error/guinea pig it is. 20mg once daily for 2 days then up to 40mg/day. Day 1 had completely 0 side effects. Day 2 nausea and vomiting, lasted until day 5..which is when constipation began. BUT my depression is under control despite environmental factors I can't control. I am less emotional, moody, or irritable in general. Suicidal thoughts don't last as long as before. I'm not a zombie. No weight gain. Its Good. Not Great. 7/10 for me. Stared 80mg today..nauseous but will subside. I'm pretty stable. Give it a chance."

   
7.0

Tiffy2211 May 18, 2017

7 users found this comment helpful.

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For Depression: "Im a 35 year old male suffering from Bipolar Disorder, Borderline Personality Disorder, Panic/Anxiety Disorder, and Anoroxia Nervosa. My Bipolar has been extremely resistant to most meds. Ill be okay on a combination of meds for awhile then they stop working. The Bipolar depression would get extremely severe and I've been on dozens of medications over the years without much positive results. After being hospitalized in a very good psychiatric treatment center I was put on a combination of meds that have changed my life. Fetzima was one of them. I've noticed marked improvement in my depression and it has also helped with my anxiety as well (which is great because I no longer need benzodiazepines which were easily abusable). Very happy!"

   
10

rajaajay (taken for 1 to 6 months) May 18, 2017

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I had a rough childhood to sum things up quickly. I was divorced and put myself through nursing school, remarried, bought a house and was very independent until I hit 30 y/o. I started to slowly decompensate mentally. My issues are Bipolar, Boarderline Personality Disorder, Anxiety, Grief-complicated, ADD, Diabetic and obesity. I tried counselling and all kinds of medications for 10 years. My husband is very supportive. Then my 20 y/o son committed suicide in the navy. It didn't hit me until about 9 or 10 months and I became extremely manic and the grief took over. I dissociated and overdosed on my Klonopin and started outpatient treatment. Thats when I started the Fetzima. It saved my life! It took about a one and a half years to work through the grief but I could NOT have done it without the Fetzima. It helped with anxiety and my deperession."

   
10

Greatfultobalive (taken for 2 to 5 years) May 9, 2017

16 users found this comment helpful.

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For Depression: "Worked best over all the other anti-depressants I've tried. Still feel a lack of motivation, but the overall mood I'm in has improved. I have been on this for about 1 year now. The only downside is the price, as there is no generic version available. I will likely have to switch again because of my insurance deductible being so high /:"

   
7.0

cj12 April 25, 2017

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Fetzima (levomilnacipran) for Major Depressive Disorder: "This is the second time I have taken Fetzima ER and have been on it for 9 months. I quit the first time due to not being able to afford it. I have MDD, anxiety disorder, panic disorder with agoraphobia, and BPD. I take the 40mg a day. At first, when I started Fetzima, I was happy, almost euphoric and my depression and most of my anxiety completely disappeared. Recently, within the past couple months, my rage has returned, I'm easily agitated and highly irritable, I have had to take my Klonopin daily for extreme anxiety, my personality has changed, and my depression has gotten much worse to the point where I cry several times a day and feel hopeless. I'm not sure whether I need to decrease or increase or try something else at this point."

   
5.0

Rebs980 April 10, 2017

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Fetzima (levomilnacipran) for Depression: "Age 60 male. Several years with BPH being managed by Xatral but TURP coming soon. Past year my depression/PTSD being managed by Cipralex 20mg. Unhappy with weight gain and anorgasmia so I was just prescribed Fetzima. Weaned off the Cipralex and yesterday was the first day of introduction of Fetzima (20mg) but within hours I developed urinary urgency and much reduced flow. Discomfort increased through the day causing pain and extreme gas/stomach bloating. So 24 hours later I'm not taking Fetzima again until I talk to the doctor. It may just be coincidental but I fear the side effect of urinary retention is a real problem with the Fetzima when exacerbated by a pre-existing BPH condition so beware!"

   
1.0

Batman57 (taken for less than 1 month) April 3, 2017

8 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "Another fail. I had the opposite side effects as most people though. I was drained. I was the opposite of constipated. I got chills/goosebumps, but painful ones. I had some sweats, but mostly painful goosebumps. I already feel like crap with depression. I don't need another medicine to make me feel worse. Cymbalta had a similar effect on me. I was sick and drained. Effexor didn't have that issue, just some nausea and I did feel energized, but it would take me 10 minutes to urinate. Fetzima was my 20th antidepressant. I am looking into a clinical trial of ECT and Ketamine. I am over those useless medicines. I can't believe this garbage retails for 400/mo. I got it at no cost with the savings card for the first month."

   
1.0

KellyKer (taken for less than 1 month) March 29, 2017

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Fetzima (levomilnacipran) for Major Depressive Disorder: "Fetzima has to be the worst drug I've ever taken for my depression. I had been on moderate doses of Prozac for 8 years prior until the drug no longer affected me beneficially. The fetzima had positive effects at first, but I think it was a placebo effect. A month into taking the drug I still felt depression and frequently spaced out/felt a mental fog. The physical symptoms also presented themselves. I began to have frequent urgencies to urinate but could not. Always a false alarm. A few week later I developed a clear discharge from my penis which I thought was the result of an STD. My results came back negative for all STDs. I have been off the drug for about two months and all side effects are no longer present."

   
1.0

bthomasdickinson (taken for 1 to 6 months) March 15, 2017

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Fetzima (levomilnacipran) for Major Depressive Disorder: "This has been a miracle drug for me. No side effects except dry mouth. Helps control my anxiety as well as MDD."

   
10

MelloJoy (taken for 6 months to 1 year) March 6, 2017

14 users found this comment helpful.

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Fetzima (levomilnacipran) for Depression: "So this drug was awesome for everything except it made me rage full. I could orgasm, no sleepiness, felt a little nausea but all meds have yucky side effects that go away after a while. It helped with concentration and motivation!! Wow I was a super star at work. Or maybe I was so used to the others SSRI's that gave me brain fog! I could jump out of bed with no problem in the morning which I never would get before. But it made me snappy, angry, mad and boil my blood! It didn't do well for anxiety. I think it gave me more. This drug must have a stimulant in it, more than one of the other ones that are more sedating. It was also the top highest tier for cost! Too much right now bc its a newer drug. Doesn't work for anxiety!"

   
7.0

Wish I could take this one!! (taken for 1 to 6 months) February 21, 2017

16 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "I have been on Fetzima for around 18 months, and this is truly a miracle drug. I have MDD, PTSD, GAD, and BED. I come from a family based in the medical field, and as such I have tried every drug on the books. Almost two years ago, my anxiety got so bad that every night I felt like I was going to suffocate and die in my sleep. I was having multiple daily panic attacks. I was started on 40 mg of Fetzima, and before the week was out my panic attacks had all but ceased. I'm now on 80 mg. I can't remember the last time I had one as bad as the panic attacks I was having before I started Fetzima. I gave it a 9/10 because I'm still sweating as a side effect. I also take Vyvanse, and Propranolol and Abilify as needed."

   
9.0

6xxxxxxxxxxxxx6 (taken for 1 to 2 years) February 8, 2017

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Fetzima (levomilnacipran) for Depression: "Update: I've been on Fetzima 5 months. It has worked better than any of the other 30 meds I've tried. It took 4 months for my arms itching side effect to go away and soreness of my mouth's upper roof and upper gums also is gone. My heat and sweating is almost all gone. If I stay on the couch, I'd have no sweating but when I did anything such as brushing my teeth I'd get so much sweating. Normally I don't sweat. These side effects do go away, so don't give up on this drug too soon. I don't get that drugged out tired feeling from the depression anymore. I do have a little anxiety from Fetzima but it is usually when I'm in bed trying to sleep more when really I had enough sleep which is good because that keeps me from escaping into bed."

   
10

Anonymous (taken for 1 to 6 months) January 27, 2017

18 users found this comment helpful.

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Fetzima (levomilnacipran) for Depression: "Made me extremely suicidal, cried uncontrollably, had severe anxiety attacks, after just 2 days of it I could not take it, and it's ridiculously expensive"

   
1.0

Anonymous December 23, 2016

12 users found this comment helpful.

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Fetzima (levomilnacipran) for Major Depressive Disorder: "For last 8 months, Fetzima has worked very well (after the initial transition period from my last medication.) Over the last 15 years, I have been on many effective anti-depressants, but after about 2-3 years these medications start to become ineffective (Zoloft, Lexapro, Cymbalta, etc). Started taking Fetzima 8 months ago, and the first month involved a lot of agitation/anger (very unlike me) and also having to adjust the dosage upward.....now at 120. Since then It has been a good experience. Feel centered and have energy. One very good side effect has been pain relief from my arthritis in my knees and back. I have dry mouth with this and every other anti-depressant I have taken. The drug is very expensive."

   
9.0

8 months' experience (taken for 6 months to 1 year) December 2, 2016

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Fetzima (levomilnacipran) for Depression: "This works better than anything I've tried. I was doing well with Strattera for 4 years then it stopped working. I did well on Wellbutrin many years, it stopped working, etc. With Fetzima I get up easily in the morning because I lay in bed for at least 15 minutes, I pet and play with my cat, have quiet time saying things I'm grateful for and sometimes I get guidance for information for my day. I don't overeat anymore, I get full fast, can only eat 1/2 as much as I used to because I get bloated which helps. My headaches went away after 2 months and my sweating is almost gone away now after 3 months. I feel good and motivated to do things. I'm not hyper like with Wellbutrin."

   
8.0

SagingRose November 28, 2016

21 users found this comment helpful.

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Fetzima (levomilnacipran) for Depression: "I too have experienced a lot of loss especially with my divorce. I started up on the Fetzima recently and I'm experiencing fairly persistent symptoms of nausea. I was at 40 mg, but I'm finding that I am having to titrate, because I just can't take the effects of the nausea. I'm trying to stick it out, perhaps go down to 20 mg a day and see where I'm at at this point. I've also tried many medications, and I'm feeling extremely frustrated and somewhat hopeless. Have other people had similar experiences on this medication as far as getting over the hump of nausea? There just doesn't seem to be a lot of options."

   
1.0

Paulfhhgggfffdf November 25, 2016

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Fetzima (levomilnacipran) for Depression: "Good so far"

   
10

Slutty November 12, 2016

3 users found this comment helpful.

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Fetzima (levomilnacipran) for Depression: "I have suffered from hereditary clinical depression for several years. The death of my mother, two loved animals (horse and dog), a divorce that is endless and painful, have all added to my depression, and a new doctor prescribed Fetzima. Now I feel totally insane. My stomach hurts every time I eat; my heart pounds to the point that I wonder if I should go to an ER almost every day; I can't fall asleep and when I do I have stressful nightmares (never had bad dreams before); and every day I feel an anger and rage that makes no sense at all. I have to remind myself to take a deep breath and not act out this new mean personality on my dogs or my friends. No matter what my doctor's opinion, this poison stops tomorrow."

   
1.0

Justwannafeelgood November 10, 2016

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