Leflunomide User Reviews & Ratings (Page 5)
Brand names: Arava
Leflunomide has an average rating of 5.1 out of 10 from a total of 116 reviews on Drugs.com. 40% of reviewers reported a positive experience, while 46% reported a negative experience.
Reviews for Leflunomide
- Ano...
- Taken for less than 1 month
- May 29, 2025
"In retrospect, I found out it wasn't even standard practice to prescribe Arava for my disease because I don't have arthritis (I have IgA vasculitis). But anyway, the rheumatologist I saw at the time in 2018 already put me through plaquenil, prednisone, and methotrexate before deciding to prescribe Arava. Oh man, did that cause some pretty bad IBS and explosive diarrhea. So I only took it for a month before I had to quit from side effects. Ironically, afterwards though, I was in remission for almost a year (as in symptom- and medication-free) before symptoms slowly started coming back in 2020. Now I'm in much better care with a different provider, but my current medications (colchicine, lisinopril) only suppress the symptoms, with me still feeling unwell, probably due to smoldering disease activity. Sometimes I almost wonder if not for the intolerable side effects, whether another short-term course of Arava could be more effective. But it's hard to say, and probably not worth taking over newer meds available."
- BH1...
- Taken for 1 to 6 months
- August 14, 2024
For Psoriatic Arthritis "Serum-negative RA diagnosis. Swollen joints and tendons, fatigue, headache, brain fog. 20 mg/day. The API is well tolerated, no diarrhea, no GI issues. Increased blood pressure. Started to have efficacy after 3 weeks. Works well. Have scalp issues not resolved yet (50% hair drop, red painful bumps not folliculitis, white scale, just started meds.)"
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- Sal...
- Taken for 1 to 2 years
- February 11, 2014
Leflunomide for Rheumatoid Arthritis "Not ONLY the pain from rheumatoid arthritis - Arava made my hair fall out, lump in esophagus, and chronic throat infection."
- Het...
- July 22, 2011
Leflunomide for Rheumatoid Arthritis "I have been taking Arava for almost 2 years. I have recently developed very high blood pressure and I'm not sure if Arava is the cause of it. We have picked up that it increased my cholesterol."
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Your review helps others make informed decisions.- ced...
- September 8, 2011
Leflunomide for Rheumatoid Arthritis "It worked wonderfully for several years until I got a tooth infection. I had to go off Arava for the antibiotics to kill the infection. Sadly, when I returned to Arava, it no longer worked for me."
- Anonymous
- March 2, 2009
Leflunomide for Rheumatoid Arthritis "This medicine gave me very bad indigestion, acid reflux, and severe nausea. My doctor cut me down to one pill every other day and it did cut all of these effects basically out."
- Anonymous
- January 13, 2010
Leflunomide for Rheumatoid Arthritis "I have been on Arava for three years now. I have not had any adverse side effects. Every so often my thumb hurts, and I have to use a pain cream, but that is my only complaint."
- JNN...
- April 18, 2015
For Rheumatoid Arthritis "I am 61 years old. Took this medicine for 8 days. Kept getting weaker and weaker. Then, barely breathing. Spent 4 days in the hospital."
- Bib...
- November 20, 2015
Leflunomide for Rheumatoid Arthritis "I could not take it, stomach problems and barfing. I am very allergic to sulfa, penicillin, and Bioxen, do not know if that had something to do with it."
- Bob...
- February 1, 2021
For Rheumatoid Arthritis "I’ve been on leflunomide for over three weeks, and I have massive hair loss. However, it is effective in helping control the pain of my fingers, hand, and right hip."
- Anonymous
- Taken for 1 to 6 months
- September 1, 2019
For Rheumatoid Arthritis "Experienced hair loss at 30 is really hard from this drug. Been off for 3 days. Flu-like symptoms, dizzy."
- Moh...
- Taken for less than 1 month
- September 5, 2020
Leflunomide "I have been taking Arava for one week for psoriatic arthritis, and I have suffered from headache and high blood pressure within a week."
- Nic...
- Taken for 1 to 6 months
- January 10, 2021
For Rheumatoid Arthritis "It works well for some, but I developed severe pain in the buttock area, awful achiness, and could not lift my pets when needed."
- Hob...
- Taken for 1 to 6 months
- August 25, 2024
For Psoriatic Arthritis "I have been on leflunomide for 2 months and feel like a different person. After 15 years of suffering, I am now virtually pain-free. I have my life back."
- chl...
- Taken for 6 months to 1 year
- August 12, 2021
For Rheumatoid Arthritis "Can someone share what they did when blood pressure was high? Like, did you stop leflunomide or just take blood pressure meds for it?"
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For Rheumatoid Arthritis "On a leflunomide daily dosage of 20 mg. It caused chronic GI upset: diarrhea and gastritis. It did relieve RA symptoms, but I felt sick for 8 months. Endoscopy revealed gastritis. I would not recommend this drug."