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Leqvio User Reviews & Ratings (Page 4)

Leqvio has an average rating of 7.1 out of 10 from a total of 94 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 6% reported a negative experience.

Reviews for Leqvio

Commonly mentioned side effects
  • L h...
  • Taken for 6 months to 1 year
  • May 28, 2024

For High Cholesterol "It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

8 / 10
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15 Report
  • Mlh...
  • Taken for 1 to 6 months
  • March 12, 2023

For High Cholesterol, Familial Heterozygous "I had a terrible reaction to Repatha, so I requested Leqvio. I had my first dose 3 months ago, and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."

10 / 10
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26 Report
  • Ano...
  • Taken for 6 months to 1 year
  • June 5, 2025

For High Cholesterol "My cholesterol is better, but I hurt all over! I don’t know if Leqvio is causing this, but I feel like I didn’t hurt this bad before!"

6 / 10
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3 Report

Frequently asked questions

  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

For High Cholesterol "Took first dose in October 2022. Bad cholesterol was 105. Second dose in January. Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer."

10 / 10
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18 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 13, 2025

For High Cholesterol "After my first injection, all seemed fine, but two weeks in I have arthralgias of the fingers and severe constipation, dry lips."

4 / 10
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4 Report

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  • Jay...
  • Taken for 1 to 6 months
  • September 5, 2024

For High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast."

7 / 10
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5 Report
  • Mar...
  • Taken for 6 months to 1 year
  • April 18, 2024

For High Cholesterol "Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
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6 Report

More FAQ

  • Fre...
  • Taken for 2 to 5 years
  • June 29, 2024

For High Cholesterol, Familial Heterozygous "Have just received my 4th injection. Further to my May '23 post. Cholesterol has remained low, slight muscle pain continues, believe it has contributed to some hair loss. Feel overall more energetic."

9 / 10
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5 Report
  • Tho...
  • Taken for 2 to 5 years
  • January 1, 2024

For High Cholesterol "Worked for me, been taking it for a couple of years."

10 / 10
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5 Report
  • Anonymous
  • April 15, 2024

For High Cholesterol "Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
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3 Report
  • Ifr...
  • Taken for 1 to 2 years
  • February 23, 2025

For High Cholesterol, Familial Heterozygous "Reduced LDL, now listed as too low. UTIs, leg pain, hand nodules. Have to wait out the 6-month dosage to eliminate it."

5 / 10
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1 Report
  • jac...
  • Taken for 1 to 6 months
  • February 29, 2024

For High Cholesterol "Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
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2 Report
  • she...
  • Taken for 1 to 6 months
  • April 12, 2024

For High Cholesterol, Familial Heterozygous "Have felt better, not had blood work yet to check levels."

10 / 10
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1 Report
  • phi...
  • Taken for less than 1 month
  • July 9, 2025

For High Cholesterol "Just had my first injection 7 days ago and I'm just experiencing lower back pain on the 6th day."

1 / 10
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0 Report
  • Ano...
  • Taken for 1 to 2 years
  • June 11, 2025

For High Cholesterol "I’ve been getting Leqvio shots for a year and a half now. I haven’t gotten any side effects so far. My cholesterol levels have dropped quite a bit. I’m satisfied with the results."

10 / 10
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0 Report
  • Ano...
  • Taken for 1 to 6 months
  • July 15, 2025

"Severe pain injection site (abdomen), abnormal bowel motion."

5 / 10
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0 Report
  • Ano...
  • May 27, 2025

For High Cholesterol "Just had my 3rd shot. No issues at all. Total cholesterol went from 292 to 167. Very happy with results."

9 / 10
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0 Report
  • Emm...
  • Taken for 1 to 2 years
  • May 23, 2025

For High Cholesterol "It has lowered my cholesterol a lot, but my doctor wants my good cholesterol increased. I have some trouble with 'charlie horses' in my legs. Am hoping that decreases so I can continue the medication."

7 / 10
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0 Report
  • Ano...
  • Taken for 1 to 2 years
  • May 26, 2025

For High Cholesterol "Has worked well for me. Will recommend it to others."

10 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.