Goserelin and Tiredness: What Users Say

• Ale...
• July 16, 2013

For Endometriosis "I am halfway through my Zoladex treatment, and it has been an absolute godsend for my pain. I'm not in any pain at all, which is exactly what I wanted. However, I am struggling with the side effects: hot flashes, headaches, weakness, night sweats, tiredness, and bone pain. I was struggling to get through the day before the treatment, and now I have these other problems to deal with. I am torn about how I feel about it. I would definitely recommend it though, as everyone has different levels of these symptoms; I might just be a bad case."

• Pet...
• May 28, 2012

For Endometriosis "I've been on Zoladex for 8 months now, I'm just having my 9th injection this week. Positive effects: endometriosis is not inflamed anymore, which increases chances of getting pregnant. No periods, therefore no pain. Side effects: where do I start? The worst is significant weight gain, tiredness, hot flushes, sleepless nights, and low energy levels. Plus, no sex drive whatsoever. But anything to have a baby."

• Pat...
• Taken for 5 to 10 years
• October 11, 2019

For Endometriosis "I have been on Zoladex for 5 years now. My hair is still falling out, which was beautiful and thick, now dry and thin. My skin is always dry, my hands sometimes crack, so I have had to take high doses of calcium as it is now thinning my bones. I also take zinc and iron to help with my hair and the constant tiredness. I take antidepressants but have terrible mood swings. However, I will keep taking the Zoladex as this by far outweighs constant hospital visits and staying in due to extreme bleeding, and then having to have blood transfusions on 2 occasions. It has changed my life as I don't have as many hospital visits and have not had to have another transfusion since."

• Tyi...
• Taken for 1 to 6 months
• March 8, 2022

For Endometriosis "Awful! Had three and experienced constant neck, shoulder, calf, and bone pain every day. I’m still experiencing these pains one month after stopping Zoladex. I was also given HRT add-back, and it didn’t help at all. Feeling anxious, tired, constant headaches, and the pain all over is terrible. Hoping once my periods return, I will also return to feeling normal."

• lou...
• Taken for 1 to 2 years
• March 13, 2016

For Endometriosis "Have been on Zoladex once a month injections for a year now. Awful side effects for the first 8 months. Terrible joint pain, hot flushes, bowel habit changes, bad mood swings, complete lack of sex drive, depression that drove me to contemplate my place on earth, lethargy. Also, massive weight gain... over 2 stones. The plus is I now am free from periods and the horrific pain I endured. Prior to Zoladex, I had an ablation where they burned off my womb lining. This was unsuccessful. Make your choice as the side effects are really awful, but the pain I suffered was so life limiting. I would be screaming out in pain, unable to move a muscle. Now I am pain free."

• Anonymous
• Taken for 1 to 6 months
• September 7, 2018

For Endometriosis "I had a laparoscopy to treat endometriosis a month before beginning the course of treatment. Monthly dose. On implant 3 of 6. The first month was the most difficult. No period after the first month. Chronic pelvic pain has subsided. Pain and bleeding on the injection site, bloating, nausea, fatigue, lethargy, dizziness, aches and pains, a heavy feeling in the chest, and pelvic cramps for a few days after injection. Hot flushes and night sweats gradually became more intense and frequent after the first month. They’re bothersome. Emotionally up and down throughout treatment with bouts of depression, anxiety, and panic attacks (have a history). Headaches, a possible cause of sleep deprivation in combination with the drug. Weight, appetite, skin, and hair - normal. I’m conflicted with how I feel about the drug. I can say not having chronic pelvic pain and a period has been relieving."

• Joy...
• Taken for 6 months to 1 year
• April 23, 2021

For Bleeding Disorder "Years of heavy bleeding. It got to the point of me collapsing in a pool of blood and being rushed into the hospital a few times on blood transfusions. Fibroids were the cause. I started on Zoladex in August 2020, only one positive is no bleeding. I can go on forever with the list of negatives. Depression, looking 9 months pregnant for the last 9 months even though I'm not. Hot sweats that are so bad at night that I sleep with a fan on full and cut off my long hair to cope. I have itchy, lumpy skin all over. Feeling tired, no infection, exhausted, due to my 10th Zoladex and still waiting for a full hysterectomy. Apparently the list is long, I'm on category 2, which is urgent. I can't see an end to this nightmare. I am hoping for surgery soon and to get my slim body back and live life again."

• Joy...
• Taken for 6 months to 1 year
• April 23, 2021

For Bleeding Disorder "Years of heavy bleeding. It got to the point of me collapsing in a pool of blood and being rushed into the hospital a few times on blood transfusions. Fibroids were the cause. I started on Zoladex in August 2020, only one positive is no bleeding. I can go on forever with the list of negatives. Depression, looking 9 months pregnant for the last 9 months even though I'm not. Hot sweats that are so bad at night that I sleep with a fan on full and cut off my long hair to cope. I have itchy, lumpy skin all over. Feeling tired, no infection, exhausted, due to my 10th Zoladex and still waiting for a full hysterectomy. Apparently the list is long, I'm on category 2, which is urgent. I can't see an end to this nightmare. I am hoping for surgery soon and to get my slim body back and live life again."

• Swi...
• Taken for 1 to 6 months
• March 29, 2022

For Endometriosis "This is my second month for this injection, the first month was so bad. I had too many side effects. The night after my injection, I had hot flashes and painful bones, especially on my ankles. Day after day, it gets worse, I had dizziness every day, constant tiredness without reason, and super fatigue, muscle pain, super vaginal dryness, and couldn’t walk longer because my feet and legs hurt so bad. But there are also good side effects, like I’m totally no more bleeding/period or even spotting, so it means no pain."

• Ang...
• February 11, 2021

For Endometriosis "I'm on my 3rd month, pain-wise 0, which is amazing. However, I feel exhausted, I mean, chronically fatigued."

• Ang...
• Taken for 1 to 6 months
• February 28, 2021

For Endometriosis "3 months in, pain-free, yes, but feel completely exhausted. Also, weight gain."