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Simponi Aria and Tiredness: What Users Say

Tiredness: mentioned by 5 users (18.5%)

Based on user experiences from 27 Simponi Aria reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 22.2%
tiredness 18.5%
eye problems 11.1%
itching 11.1%

Reviews for Simponi Aria

Commonly mentioned side effects
  • V V...
  • Taken for 2 to 5 years
  • October 2, 2020

For Rheumatoid Arthritis "I have been on this for about 5 years and have had RA for 40 years and tried lots of medications. But this one works for me the best. I also take Methotrexate with this, and I have been free from illness over the past 3 years. I am only tired the week that I get the infusion, and then I am fine after that. Glad to be able to move like I want to most of the time."

10 / 10
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31 Report
  • Chr...
  • Taken for 1 to 6 months
  • January 4, 2020

For Psoriatic Arthritis "Was doing fine for about 12 weeks. Then I broke out with a whole new form of palmoplantar pustule psoriasis, and my regular plaque psoriasis came back almost vengefully to the point where my skin feels like it is burning. I had my first infusion in August, then again the second one 4 weeks later, and by the middle of my 8-week stretch was when these rashes happened. My first three days after the infusion, I experienced vomiting and extreme tiredness, but overall I felt fine. The second infusion was pretty much the same, but then all this happened. I am so sore on my hands and feet it feels like I am walking or touching broken glass. I have to wear vinyl gloves to keep the moisture on my hands and keep my feet wrapped with non-stick gauze and taped and covered so I don’t develop a secondary type of infection from something else. I can’t take the pain, so my husband has pushed me to hire a cleaning lady to do my housework because all I am able to do is lay around. This is no way to live."

1 / 10
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18 Report
  • Tuc...
  • August 9, 2016

For Rheumatoid Arthritis "I have had 3 infusions, and I am tired all the time and just want to sleep. My vision has also been more blurry. I understand the immune system can be lower on Simponi. I now have shingles on my face, and I had the shingles vaccine two years ago. I have had RA for 33 years, and Plaquenil has helped me more than anything as far as stiffness and pain. I have been taking it for at least 20 years. I also take Celebrex and methotrexate."

2 / 10
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24 Report

Frequently asked questions

  • dre...
  • Taken for 1 to 6 months
  • February 20, 2023

For Rheumatoid Arthritis "I had my first infusion and was totally exhausted after it. Within two days, though, I felt fine. My hands are not as stiff, and I can feel a difference in my feet. I am getting my second infusion this week and hope it continues to improve my rheumatoid arthritis symptoms."

6 / 10
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7 Report
  • Han...
  • Taken for 1 to 6 months
  • September 22, 2019

For Psoriatic Arthritis "I received Simponi Aria infusions from 12/2018 to 6/2019. I’ve had 4 UTIs, the last infection on 9/2019 went to my kidneys. I was hospitalized with sepsis. Now I’ve been referred to a hematologist due to high myelocytes. I always feel sick, tired, weak... I’ve also been prescribed Lipitor for extremely high cholesterol. I’m a vegetarian and eat healthy. I’ve never had these problems prior to Simponi Aria infusions."

1 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.