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Glecaprevir / pibrentasvir User Reviews & Ratings (Page 3)

Brand names: Mavyret

Glecaprevir / pibrentasvir has an average rating of 8.4 out of 10 from a total of 417 reviews on Drugs.com. 79% of reviewers reported a positive experience, while 8% reported a negative experience.

Reviews for Glecaprevir / pibrentasvir

  • NotHa...
  • Taken for 1 to 6 months
  • June 19, 2018

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "This medication cured the Hep C, but left me in debilitating joint pain. I wish I never took the treatment. I have been in good health, fit and energetic, and had normal liver function, with a high viral load. I waited 16 years and took the drug because of its claim of minimal side effects. I walk with a cane and limp if I don't have my cane. I would wait until it is improved. It's been 3 months since completing the treatment. I am still HCV not detected, but my life as I knew it seems to be over. Buyer be warned."

5 / 10
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  • Dennis
  • Taken for 1 to 6 months
  • July 7, 2023

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I took my dose after supper, approximately 7 pm each day for 8 weeks. The first 3 weeks I could tell I'd taken a large dose of medication, but no major symptoms beyond that. After week 3, I had no ill effects from the drug at all or so minor it wasn't that noticeable. Approximately 6 months after finishing treatment and having no Hep C in my bloodwork, my joints began to ache - hips and shoulders mostly - to the point I could barely push covers off me in bed. After 3 weeks of that and the pain diminishing, my hands began to feel weak and painful while my shoulders pained me somewhat, and my hips were almost completely free of pain. I do not know if the Mavyret is responsible for my weak, stiff hands, but I'm only mentioning this so if somebody else has the same symptoms. I have visited a rheumatologist twice and have no markers for RA in my bloodwork, and X-rays show only normal wear for a 76-year-old."

6 / 10
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  • Well
  • Taken for 1 to 6 months
  • January 19, 2021

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Y'all, I have had a good experience with Mavyret. I have been on this medication for almost a month with no side effects. Gotten my first blood work, it was non-reactive. I have 4 weeks to go. Please, whoever is reading this, don't be scared like I was. It is worth every penny. Make sure you eat on it and drink a bottle of water. Take it at night at the same time, and you will be fine. It's a one-time go to be cured. I hope everyone has the same positive reactions. God bless and good luck."

10 / 10
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Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • September 2, 2020

Mavyret (glecaprevir / pibrentasvir) "I've been taking Mavyret for 5 days. I have a slight headache sometimes, and I feel quite tired, but apart from that, I'm fine so far. Cool to read others' experiences with this. Seems my symptoms are fairly normal. Gonna be weird being well after 40 years, but I'm ready!!❤️❤️✌️✌️"

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  • Jok
  • Taken for 1 to 6 months
  • August 20, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I'm on week 7. Not sure what to say about side effects, but most I've had are not listed. Heartburn within 45 minutes of taking every time, heavy weakness that feels like I'm being pulled down to the floor, lasting 4-5 hours after taking. Dizziness and a spaced-out feeling. Some brain fog, but it seems to have gone away. I take Mavyret after the noon meal, and I'm basically worthless for about 5 hours, mornings are okay, no sleep problems. The main problem is heartburn and acid reflux, you can't take anything for the reflux, so that makes it worse. Thanks to everyone for posting, as this is the only place you can see all the real side effects."

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Are you taking this medicine?

  • Sam
  • Taken for 1 to 6 months
  • September 22, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "This med definitely has its ups and downs. Make sure you take it with food right before bed! It will create BAD insomnia otherwise. My main symptoms were being restless, sore, nauseous, headaches, clammy, and occasional diarrhea. I was so exhausted the whole treatment. I did get a cold for about a week during it as well. I also went to the chiropractor during this treatment to help with back and body pains. I also saw a counselor during this process as well. You have to keep up with the little things that keep you sane during this process because you’ll feel depressed and miserable. Just do what you can and don’t worry about perfection right now. It’s for a short time, and soon you’ll be able to say you’re hep free like me!"

8 / 10
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  • Joy
  • Taken for 1 to 6 months
  • July 4, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Started 8-week Mavyret treatment on June 3, 2019. First 16 days were good. Then had flu-like conditions for 10 days. Don't think it was related to treatment. Overall, treatment has been good. I noticed I’m more tired and have a little less energy. I’ve lost weight, but that is due to the flu or virus or whatever it was! I started with a viral load of about 6 million. Got my 4-week test done, and I am now down to 15. A little disappointed it is still detected, but sometimes that happens, and I’m sure by the time I am done, it will be gone. My advice is the same as everyone else's: lots of water. I take my pills at dinnertime. The AbbVie nurse who calls to check on me is wonderful. I will be glad when all of this is just a bad memory. Good luck to everyone."

10 / 10
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More FAQ

  • Monica...
  • Taken for 1 to 6 months
  • December 6, 2017

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I'm on my last six days of my eight-week treatment. First round of labs is looking promising. Second set is next week. *Fingers crossed.* And the side effects are very real, and no, I'm not just stating a headache, nausea, and fatigue. About four weeks in, I noticed a mental decline. Bouts of depression, anxiety, and at times immense irritation, plus facial blemishes, thinning hair, weight gain, and excessive sweating. Worth it, I hope, considering if one stops treatment, the likelihood of insurance authorizing another is very unlikely. I have always had adverse reactions to medicines (my luck), ultimately, the potential benefits are worth it. Treatments' alleged side effects suck vs. Hep C and its damage... treatment was an easy win."

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  • DeeDee
  • Taken for 1 to 6 months
  • April 15, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Two weeks of Mavyret treatment to go. Occasional loss of appetite, sometimes a slight headache, but not even needing an aspirin. No aches, brain fog, fatigue, or nausea. Blood work at four weeks showed I hadn't cleared the virus completely, but my count went from over 1 million to 15. 15.....! Almost there! I take the pills around 7 PM with food, hasn't affected my sleep, energy level, or concentration. Based on my experience 18 years ago with Interferon/Ribavirin, (virus came back after 18 months of that brutal, life-sapping treatment, during which it went undetectable) I was expecting the same side effects, if of a lesser intensity. I'm calling this the miracle we've been praying for."

10 / 10
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  • Krisg
  • Taken for 1 to 6 months
  • October 4, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I just finished my 8-week treatment the day before yesterday. I had extreme fatigue, I was very depressed and thinking crazy stuff, had nightmares, was in a weird sleep the first few weeks, like couldn't sleep, but maybe I was asleep... I don't know, just weird. Had diarrhea a few times and just very weak. I have 2 babies and could barely take care of them some days! It was a nightmare! I'm glad it's over! I haven't had blood work yet but will in a month. My doc told me to take 12 weeks but apparently got changed to 8 at the end but said it was 8 whole time. I'm pretty sure it was Medicaid not wanting to pay for more, and my doc is lazy! I stopped the day before yesterday and can't stop throwing up and having diarrhea today must be a bug I'm guessing. I was diagnosed in 2015 plus had some other liver issues besides hep... wish everyone luck! It's not easy but can be done! I wish I would have known about this treatment a few years ago!"

3 / 10
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  • Spooks
  • February 22, 2020

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Day 7: I feel that around 2 hours after I take the medication, I get really nauseous and dizzy. I feel that it lasts about 2-3 hours. Once that goes away, I feel fine besides the little heartburn I’ve been getting. I’ve been thinking about taking the medication at night with a snack before bed so that all the side effects happen then. I’m super grateful for the opportunity. I tried to get medication for this in 2012 and kept getting denied because of my insurance. So glad I’m able to take on this journey to freedom."

7 / 10
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  • Careb...
  • September 23, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Took Mavyret for 8 weeks. Finished April 22nd and the virus is undetected. Feel blessed to have gotten rid of it. So it’s been a full 5 months since I finished. The first 3 weeks taking Mavyret, I had no side effects, but for the remaining 5 weeks, I felt like death. Never been that sick in my life (extreme fatigue, brain fog, depression, chest pain, right tightness, irritable muscle weakness, itchy skin, nightmares, nauseous). Was in bed 20+ hours a day. Good thing is I’m starting to feel better, but very slowly. Most days I have nausea. Fatigue (I’m in bed 15 hours a day), bone and joint pain, irritable. But every day gets a tiny bit better. This has been challenging, but I’m cured. * Also, has anyone else had a recurring candida infection after or during Mavyret treatment?"

10 / 10
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  • Maree
  • Taken for less than 1 month
  • April 18, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I am 44 years old (female) and have had hep C (geno 3a) for 19 years. I started experiencing fatigue in the last 3 years, but my liver is generally in good health considering. I contracted it off my partner, who had been living with the disease since the early '80s. He had tried interferon twice, but unfortunately, he died of liver cancer 3 years ago. I am sad that he never had the opportunity to try this wonderful drug. I am now on day 9 of my 8-week treatment. A few side effects... vivid dreams first 2 days; very tired; REALLY bad nausea. It’s only 8 weeks, so I just keep trucking. After watching my partner go through horrendous side effects from interferon, I count myself very lucky. I have a lot of confidence in this new drug. Good luck to all on the treatment."

8 / 10
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  • Debra
  • Taken for less than 1 month
  • January 29, 2020

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I just finished one month of treatment on Mavyret, and the side effects are definitely easing up. The effects at first were harsh: flu-like symptoms, fatigue, tummy ache, fogginess, and probably the nausea was the worst of all for me. (I suffer from migraines, so I’m more sensitive to nausea), but it’s lessening as I enter into the second month. I go for a first-month checkup on Monday, so I’m hoping things are looking good. Do the treatment, your health is the first priority. You will get through this, and once you're hep C free, this will be a distant memory. Good luck, fellow patients!!!"

8 / 10
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  • Kellb...
  • Taken for 1 to 6 months
  • January 11, 2020

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I did the 8-week treatment after getting hep C in 2004. My levels were pretty low when I started the medication, and a CAT scan shows stage 2 liver fibrosis. I had zero negative side effects. On day 3, I did begin to get a lot of energy, almost to the point of feeling nervous, but I was getting so much accomplished because I had energy to do things. I had my levels checked after I finished, and they were below 12, which means it is normal. I go for my 3m in a few weeks, and we will see if it stayed negative."

10 / 10
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  • Drea
  • Taken for less than 1 month
  • March 17, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I'm on my second day of Mavyret. Haven't had any side effects yet, so that's a good sign. Have waited 20 years for this, and I'm so happy it finally came on March 15, 2019, at 12:45 PM. I'm doing the 8-week treatment, and it comes in 4 small boxes (for a month with 7 individual smaller boxes (in slots) with the 3 pills in each one, one box for each week. You take 3 pills at once, and my doctor told me to eat at least 30 minutes before you take it and drink lots of water the whole time you're on the treatment. This way it would help with the side effects. So for 2 days, I've been drinking lots of water, and I eat a healthy meal 30 minutes before taking my pills. I decided to eat at 5 PM and take my pills at 5:45 PM. Gave myself 15 minutes to eat and 30 minutes for my food to settle a little bit. And since my doc said it could cause fatigue, I chose to take it after dinner just in case I get tired. This way my whole day isn't wasted by being even more tired than usual."

10 / 10
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  • Leelee
  • Taken for less than 1 month
  • October 18, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Today is my first day on the treatment. I'm nervous about the side effects, but I'm grateful that I have a chance to cure my hep C. Thanks, everybody, for your experience, it helps prepare me just in case."

4 / 10
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  • Rissa
  • Taken for 1 to 6 months
  • March 3, 2020

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I completed the 8-week course of Mavyret a few weeks ago. The beginning of taking it, I had a real bad headache for about a week and trouble getting to sleep, but after the headache went away, I had no other side effects. Waiting for the results of the blood testing to see if it worked, but I am hopeful. Will update results upon. I was very nervous to do this treatment, but it went pretty easily, minus the headache."

9 / 10
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  • Suppa...
  • Taken for 1 to 6 months
  • September 15, 2018

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I’m cured. Genotype 3. I did 16 weeks because I had prior unsuccessful treatment with interferon and ribavirin. Just did a blood test after 3 months at the end of the treatment, and the virus is undetectable, which means I’m cured. I feel thankful and amazing. Thanks for Mavyret. Let’s eradicate this disease."

10 / 10
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  • MMC
  • Taken for 1 to 6 months
  • September 15, 2018

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "My 63-year-old brother died today. He took Mavyret for his Hep C. Cancer was not detected. Under a year after taking this medication, he died of cholangiocarcinoma (bile duct cancer). We don’t know yet of the connection, but he did not have it before. He was in healthy shape. He was diagnosed on August 6, 2018, and died today, September 15, 2018. We are heartsick."

1 / 10
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  • Marie
  • Taken for less than 1 month
  • August 26, 2020

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I'm on my third week of Mavyret. At my two-week mark, they did lab work to make sure the medicine was doing its job and not making it worse. Almost a month ago, my liver functions were at 160 and 116. On my third week, my lab work came back, and my liver functions are 27 and 16."

10 / 10
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  • Their...
  • Taken for less than 1 month
  • December 26, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Day 4 on Mavyret. I am taking it at 10 PM before I go to sleep. I have had slight nausea during the day but have not thrown up. I don't feel tired, but my body feels weak. I have extreme thirst. I drink 3 cups of water at a time and still can't quench my thirst. Other than that, not much to report. Got a ways to go, but overall, it's not too bad."

9 / 10
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  • LAMike
  • Taken for 1 to 6 months
  • August 26, 2018

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I am 4 1/2 weeks into treatment out of 8 weeks. Week 4, I notice my cognitive thinking is improving. And my depression and anxiety is a 2 out of 10 today. Before treatment, it was a constant 5-8. Still have hep C effects. Like fatigue, soreness in my knees and ankles is still there. But less. My energy level is almost 50%, and soreness in my joints is subsiding. Plus, I have very few side effects from the treatment, which are minimal, not even worth mentioning."

10 / 10
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  • Hol
  • Taken for 1 to 6 months
  • May 27, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "Had hep C over 30 years, took Mavyret 8 weeks, finished a year ago end of May. I have tested 3 times since, no active virus, normal liver panels, still get pain in liver area occasionally, do have fatty liver, working on lowering carb intake. Side effects were not great, anxiety, sleep problems, depression, first and last week were unbearable, stomach felt like a hole burning in it. The best time to take meds was with a huge meal around 7 PM... then go to bed. I did notice I have raised tiny bumps scattered all over my body, were never there before, but at least I have more energy and can do family outings now..."

8 / 10
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  • Grate...
  • Taken for 1 to 6 months
  • March 26, 2019

Mavyret (glecaprevir / pibrentasvir) for Hepatitis C "I was diagnosed in 2012, was advised not to seek treatment as new meds were coming out. Took me until now, 2019, to put enough clean time together to be approved for meds. I’m on my last two days of an eight-week treatment. Blood work done four days ago shows I have cleared the Hep C!! Have experienced extreme fatigue and light headaches. First week felt flu-ish. Wondering how long after stopping did other people notice their fatigue end? My doc swears that it’s immediate and that I will also see how tired the Hep C was making me prior to treatment. So grateful for this medication; also grateful it was covered by insurance."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.