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Fluticasone / salmeterol and Mucus: What Users Say

Brand names: Advair Diskus, Wixela Inhub, Advair HFA, AirDuo Respiclick

Mucus: mentioned by 7 users (2.6%)

Based on user experiences from 274 Fluticasone / salmeterol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

shortness of breath 14.6%
cough 11.3%
sore throat 8.8%
chest pain 5.5%
headaches 5.5%
thrush 5.1%
increased heart rate 4.0%
mucus 2.6%
anxiety 2.2%
dizziness 2.2%

Reviews for Fluticasone / salmeterol

Commonly mentioned side effects
  • LTa...
  • Taken for 1 to 6 months
  • March 6, 2021

Fluticasone / salmeterol for Asthma, Maintenance "Terrible! Insurance just changed formulary, adding Wixela Inhub and dropping Advair for what they'll cover. I noticed a difference within a week, needing to use my albuterol inhaler nearly daily now when before hardly ever. I have a lot of mucus now when I didn't before. Everyone should be complaining to the FDA and their state insurance commissioner. Insurance companies should NOT be able to cover only cheaper drugs when they don't work, and the FDA should require this drug to be taken off the market. Horrible."

1 / 10
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143 Report
  • MBa...
  • Taken for less than 1 month
  • May 8, 2020

Fluticasone / salmeterol for Asthma, Maintenance "Wixela is the worst! I was given Wixela for asthma maintenance at the worst of times (Pandemic). Everything you fear about COVID-19 is just about the same side effects as Wixela. I couldn’t stop coughing and have never had so much phlegm in my throat. I was horrified! Suffice to say, after taking Wixela for 3 weeks in March, I stopped as it was the only new thing I introduced to my body, and 2 days after stopping, my cough and phlegm disappeared completely. If it wasn’t for my wife not getting sick, I would’ve thought I was infected with the virus."

1 / 10
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62 Report
  • Sic...
  • Taken for 5 to 10 years
  • August 27, 2020

Fluticasone / salmeterol for Asthma, Maintenance "After using Advair for years, I was given a Wixela prescription. Within a month of using, I now sound like I did years ago before treatment began. Cough, irritation to the throat, and mucus. Had none of these with Advair. Insurance won’t pay for Advair since the generic is available, and the generic is making me more sick. There has to be something we can do!!"

1 / 10
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55 Report

Frequently asked questions

  • CCa...
  • Taken for 1 to 6 months
  • June 17, 2020

Fluticasone / salmeterol for Asthma, Maintenance "I had to switch to generic due to insurance. I started using this a month ago and found my symptoms have increased. I have a lot of phlegm and coughing a lot. Due to the cough, I am sleeping less and feel tired during the day and very little energy. I have a call into the doctors to send a script for Advair 250/50 and will have to pay the high cost."

1 / 10
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48 Report
  • Kya...
  • Taken for 1 to 6 months
  • September 8, 2020

Fluticasone / salmeterol for Asthma, Maintenance "Very disappointed with Wixela, this new generic asthma medication. I was on Wixela Inhub for three months and finally had to go back to my doctor to get Advair. I had constant coughing followed by phlegm and chest congestion. I was using my emergency inhaler several times a week and several times on prednisone. I started using over-the-counter cough medication just to stop the coughing so I could sleep. During the day, I used throat lozenges to keep the cough from starting. I talked to the pharmacist about the differences between Wixela and Advair and was told that it had the same ingredients, except the fillers might be different. Some generics just don’t work, and pharmacies need to listen to the patients. The price difference is insane!"

1 / 10
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46 Report

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  • Sou...
  • December 16, 2017

Fluticasone / salmeterol for COPD, Maintenance "I've been on Advair Diskus 250/50 for almost one month since being out of the hospital where I coded from COPD. Needless to say, I have quit smoking after 30 years (cold turkey). I can actually breathe & no more wheezing. Only drawback is financially, it costs $530, and I now have thick mucus in the back of my throat that I remember having when I once had pneumonia. My throat stays sore, and I am so afraid of coming down with pneumonia. Because of this, I am going to try using Advair once a day instead of twice a day. I also have nasal drip all night as well."

9 / 10
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  • Owl...
  • June 27, 2021

For Asthma, Maintenance "I was switched to this medication after my asthma had slightly deteriorated. Initially, it seemed to be helping, but then it went downhill. My breathing got worse, with asthma far more severe than ever before. I began using my reliever inhaler every day, then multiple times a day. It felt like someone was standing on my chest, I was constantly coughing, lots of mucus, pain and tightness. Exercise triggered serious asthma attacks. I was given steroid tablets to bring it back under control, but it quickly deteriorated again once they’d stopped. I went on the steroid tablets again for another week and made a decision to stop the Seretide (UK name) and go back to using a separate steroid inhaler, Clenil, and the reliever. I felt immediately like some pressure had been removed, and when the steroids stopped, it didn’t deteriorate in the same way. I don’t understand why my asthma nurse was so keen for me to use it, and it was hugely detrimental for months."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.