Fluoxetine for Persistent Depressive Disorder User Reviews

Brand names: Prozac

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Rating: 7.0

Fluoxetine has an average rating of 7.0 out of 10 from a total of 5 reviews for the off-label treatment of persistent depressive disorder. 60% of reviewers reported a positive experience, while 20% reported a negative experience.

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Cam...
Taken for 5 to 10 years
July 11, 2019

"I went through a litany of cocktails like just about everyone to try and help my persistent depressive disorder. Fluoxetine has worked the best so far in almost 20 years. But I am medication resistant, so going on 5 years off and on. Weight loss was a good side effect."

9 / 10

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12 Report

Atl...
Taken for less than 1 month
August 22, 2021

"It's my 3rd day, and I feel calmer. My mind is at ease, not overthinking, and it makes me sleepy most of the time. So now I'm trying to drink strong coffee with it, and it wakes me up, with calmer thinking. But I would wish it doesn't make me sleepy, due to driving a lot for a living, and so kind of hard, but it works. I have 10 mg. I've been having anxiety and depression."

8 / 10

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1 Report

Kar...
Taken for 6 months to 1 year
April 21, 2025

"After trying Vilazodone (Viibryd), which gave me brain zaps, insomnia, and hallucinations, and Escitalopram (Lexapro), which did absolutely nothing, Fluoxetine (Prozac) works at 10 mg and has no side effects for me."

10 / 10

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0 Report

Frequently asked questions

juz...
Taken for 2 to 5 years
June 29, 2013

"This medication is a godsend. If I didn't get put on this, my life would still be upside down. It makes you sleepy a lot of the time."

7 / 10

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19 Report

Hiy...
Taken for 1 to 2 years
November 10, 2021

"Not good for me. Still felt like rubbish, had an attempt, then they switched me off, panic attacks, anxiety, all of that. Try it though, it might work for you. It just didn’t for me."

1 / 10

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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.