Evolocumab and Shortness Of Breath: What Users Say (Page 2)

• MGC...
• Taken for less than 1 month
• November 28, 2021

For High Cholesterol "I wanted to share an experience of a close relative who was diagnosed with necrotizing autoimmune inflammatory myopathy due to this medicine. They were an independent individual about 65 years old who didn’t respond to statins and was given this medicine. She started to experience muscle weakness, ended up 15 times in a hospital for 5 months until she was diagnosed. She ended up with sepsis and respiratory failure, which ended up killing her. Please try diet, exercise, and avoid this medication. I think it’s just being pushed just to make money. References don’t show muscle weakness as a side effect."

• Bob...
• Taken for 6 months to 1 year
• August 8, 2024

For High Cholesterol "I had to quit taking it, it was causing breathing problems along with swallowing issues. I noticed my blood pressure up at times. I had a dry mouth. It did reduce my LDL, but the side effects were terrible."

• DON...
• October 27, 2021

For Cardiovascular Risk Reduction "I only had a score of 36 on my calcium heart scan... really low, I was happy about it... but, the cardiologist's office called me like I was going to have a heart attack immediately. Kept pushing me to take this Repatha. I was really hesitant to try it as I had tried a statin drug years ago, and that was really hard on my body - I literally collapsed on that drug. It was as if my muscles had melted off of my leg bones. Well, three months into Repatha, I'm having severe hip pain, and I'm stopping Repatha immediately. I hope to God it goes away as it is an awful, nagging pain without causation. I also experienced a frightening episode of shortness of breath for absolutely no reason. I almost went to the ER because I just couldn't breathe. It passed in a few minutes, but what is this drug? Anyway, I would NOT recommend this... NO WAY. It just isn't worth it in my opinion."

• Kat...
• Taken for less than 1 month
• November 9, 2021

For High Cholesterol "I took Repatha Pushtronex on Feb. 15, 2021. I had to go to the ER, with leg swelling, itching face, had an X-ray of lungs, coughing, couldn't breathe or swallow, my face was bright red, headache, and high BP. In the following days, I could not urinate, had back pain, hard bladder, went to urologist, and urine was clear, put on cranberry, probiotics, prebiotics. Saw gynecologist because of pain in belly and ordered a sonogram, but it was still bladder/back pain. My face broke out, DRAINING visits to the dermatologist went through 4 tubes of hydrocortisone valerate, no relief. Went to GP, she sent me back to the dermatologist and on clindamycin face gel and pills for my face as it looks to be bad acne. Never had my face look like this. On Benadryl, itching, burning since Feb. and it's Nov. 9th! I am suffering. Cardiologist has no answer. Repatha 800# says, 'We don't know when it will get out of your system, it lingers.' 9 months? POISON."

• Bea...
• Taken for 1 to 6 months
• February 11, 2021

For High Cholesterol "I’m 68, active female. High cholesterol of 350. I’ve taken the Repatha shot twice after trying Praluent a year ago. The injection stung more than Praluent. Small headache most days, but not terrible. Runny nose and small cough every day. Started with dizziness within three days. Vertigo soon after. Hard bumps, rash on my back. Within ten days, I had fatigue and malaise. Stopped my daily walks. Muscle soreness, not terrible. Breathing difficulty sometimes, like I was at altitude. Weird pangs in my heart started the third week. Sleep apnea during afternoon naps. I'm not taking my scheduled dose this week. It’ll take 60-90 days to be out of my system. I can’t wait. I’m sure it helps with my LDL as the Praluent did a great job too, but at what cost? I’ll go back to Crestor and deal with its side effects again. This drug is scary. Monoclonal antibodies for my liver? No thanks."

• Dan...
• Taken for less than 1 month
• March 18, 2022

For High Cholesterol "Active 60-year-old. No previous cardiac history. No co-morbidity issues. Previous statin-related susceptibilities. Additional medication included 40 mg pravastatin. After the first dose of Repatha (4 days), began experiencing severe night sweats. Increased mucus production. Difficulty breathing and swallowing (waking several times during sleep). By the 5th day, symptoms progressed, including significant leg muscle cramps as well as chest pain (no previous history). ER visit for chest pain indicated normal EKG, elevated blood pressure (150/100). Overall malaise and lack of energy."

• Pap...
• August 22, 2021

For High Cholesterol, Familial Heterozygous "I am a 66-year-old male with familial high cholesterol and triglycerides. I have been unable to take statins and other meds for lowering cholesterol due to elevation of muscle enzymes, which causes muscle pain and weakness. After a stent, the doctor wanted me to take Repatha. I took it for 5 months, and due to other health issues, I did not realize I was having issues until a heart catheterization came back normal. I had chest pressure, shortness of breath with minor exertion, sweating very easily, body aches, fatigue, back pain, and muscle aches all over. My muscle enzymes test, which I had to request, was very elevated. I immediately stopped Repatha. Chest discomfort stopped immediately, breathing is better, and sweating stopped, but I am still having severe back and muscle aches in my legs, with my legs feeling very rubbery. My advice is to pay very close attention to muscle aches if you take this medication and have problems with other cholesterol medications."

• Flu...
• Taken for less than 1 month
• July 2, 2021

For High Cholesterol "Repatha Pushtronex 2/15/21, leg swelled, tingling, lips went numb, face red, called Dr. On Benadryl. Feb 16, cough, sneeze, dripping nose, and began to itch, tongue swollen, lungs full, asthma attack, cannot eat, cheeks swollen inside mouth and tongue, went to ER. Cheeks, forehead broke out with hardened lumps under oozing sores. Feb 21, urine strong, bladder stiff, hard to pee, no UTI = urologist on probiotics/prebiotics w/ cranberry. Chest X-ray and bloodwork, use inhaler. 3/1, face still badly oozing, BP high, huge sore on nose, I think my face is scarred. Sore throat, ears ache. Reported to FDA with photos of face. Called Repatha 6/21/21, and I want to know long-term side effects. They told me, 'Hard to say, could linger in the body, I have no answer.' I'm itching, miserable. Went to urologist 2x and dermatologist = 4 tubes of hydrocortisone for face. Eye Dr. because dermatologist could not treat eye sore. 6/30/21, saw GP Dr., she has no answer. Using hydrocortisone cream and Benadryl still 7/2/21."

• Jas...
• Taken for 2 to 5 years
• July 22, 2021

For High Cholesterol "I'm so glad I read these reviews. For months, I tried to figure out why my calves were tightening up every time I walked even a block. I used to walk all day on the weekend. I walked everywhere I had to go, no matter how far, now I can't even walk a half block. Now the right side of my head feels like it swells every night. I even went to the ER a few times and they couldn't figure out what was wrong, so I just had to wing it. Also, I can't even carry my grandbaby because I get shortness of breath as soon as I start walking. I took a stress test, and my heart and arteries are fine. I came across these comments just by looking up how much the drug costs. I'm so glad I came across these comments, I want to thank everybody because I'm feeling all of these symptoms and couldn't figure out where they were coming from. Now I know I'm not taking this drug no more. I've been on it for a few years and had these problems but never thought it was this drug. Thank you."

• Ire...
• Taken for 1 to 6 months
• July 11, 2022

For High Cholesterol "Took second dose yesterday morning, last night feeling weak and I feel like my throat is closing up. I feel like I can't swallow and have a lot of mucus or phlegm, my body is hurting, my joints are hurting, and shortness of breath. I don't want to die :("

• Doc...
• July 30, 2021

For High Cholesterol "I’ve been taking Repatha for seven months, every two weeks, 140 mg. For the first three months, I had mild myalgia and fatigue; not severe enough to discontinue dosing. After that time period, I’ve experienced shortness of breath, severe myalgia, and joint pain. Additionally, my vision is periodically blurry, and I developed a UTI. Recently, I was simply walking, and my right knee popped, causing pain so severe weight-bearing was difficult to impossible. An MRI revealed a torn medial meniscus, sprains of the ACL and MCL, as well as bruising of the medial tibial area. I am scheduled for surgery in two weeks. Unfortunately, my left knee is painful in the same area. I have decided to discontinue this drug and will inform my cardiologist of my decision."

• Ano...
• Taken for 6 months to 1 year
• April 22, 2025

For Cardiovascular Risk Reduction "Been on this drug for about a year and experienced trouble breathing and a lot of mucus production. It lowered my cholesterol but strong side effects with each injection."

• Jel...
• Taken for less than 1 month
• October 18, 2019

For High Cholesterol "After the first injection of Repatha, I felt terrible, severe pain in the shoulder, neck, and elbows. Went to the ER with shortness of breath. I am finished."

• DJW...
• Taken for 1 to 6 months
• March 12, 2025

For High Cholesterol "While this drug does what it is supposed to do, lower cholesterol, the side effects were unbearable. Back pain, shortness of breath, headache, muscle pain, severe fatigue."

• Anonymous
• Taken for 10 years or more
• May 19, 2023

For High Cholesterol "Symptoms I experienced included a slow or fast heartbeat, muscle pain, and weakness, blurred vision, difficulty breathing, chest pain, numbness, and sudden episodes of a fast heartbeat."

• Jel...
• Taken for less than 1 month
• October 16, 2019

For High Cholesterol "After the first injection of Repatha, I felt terrible, severe pain in the shoulder, neck, and elbows, went to the ER with shortness of breath. I am finished."