Evolocumab for High Cholesterol User Reviews (Page 5)

• Cga...
• May 16, 2021

"I started Repatha because statins were causing heartburn, muscle aches, and dry mouth. After the first dose, I was OK, but after the second dose, I had a nosebleed that soaked several paper towels and lasted about 15 minutes. I googled to find out if that is normal and found that nosebleeds are common in women over 60, which I am. I also had constant nose dripping like water and fatigue so bad that I could hardly make it to my mailbox. Some shortness of breath as well. After several unexpected nosebleeds at very inopportune times, I stopped it."

• Lyn...
• Taken for 1 to 2 years
• September 26, 2018

"I started using this on 5/17. Effects after first taking were very bad. Got very sick, like the flu. Wasn’t going to take any more, but I talked to a pharmacist who suggested I give it another try. I couldn’t take statins, so this was prescribed. My cholesterol was over 300. Side effects seemed to be not as bad. My cholesterol went to perfect numbers. But now, over a year on this, my blood platelets have dropped. A lot of bruising. My red blood cells have enlarged and fewer of them. I have stopped taking this drug. Hoping my blood levels can be restored. Have been referred to a hematologist. Do not recommend. Wish I had done more research instead of just listening to my doctors."

• Pop...
• Taken for less than 1 month
• December 14, 2019

"Took two Repatha injections (over a two-week period) and then went to the ER and spent 4 days in the hospital. Two weeks later, I am still in severe pain. Lower back, in the liver area, feels very sharp and burning pain. Shingle-like pain throughout the upper body. I thought I was having a heart attack at one point. Taking pain pills every 4 hours just to exist. Terrible, evil drug."

• Bet...
• Taken for 1 to 6 months
• May 3, 2019

"I have had 3 Repatha injections so far. My 3rd injection was on a Friday. That night I woke up with chest pains. I am a heart patient. Have 1 stent. I thought maybe my heart was acting up again. Went to my doctor, told him. I asked if it could be the Repatha. He said he really didn't know. Wasn't a lot of info on it yet. He only has 3 patients on it. That weekend, still had pinches in my heart and nausea, where I vomited. (No, it wasn't a heart attack.) By Tuesday, no more pinches in my heart. I really think it was the Repatha. Scared to take another injection in case it does make me have a heart attack."

• Wil...
• Taken for 5 to 10 years
• February 20, 2025

"I have been on Repatha for 7 years, and I have seen great results in the drop of my cholesterol numbers. Initially, I had some muscle tightness, but that went away. In the past 6 months, I have had a new problem swallowing food and liquids to the point of choking. I did not think it was related to my Repatha, but my cardiologist asked me to stop taking it for a couple of months. I have seen an ENT specialist, and they concurred to stop the usage of Repatha as well. Two months without Repatha, and I can now swallow my food and liquids without the fear of choking to death. I have a visit next week with my cardiologist to discuss next moves. My recent blood work shows my cholesterol level rising substantially. I am not sure why I had the allergic reaction to the Repatha after all the years of using it."

• Can...
• Taken for 1 to 6 months
• September 9, 2018

"I took Repatha for 6 weeks and started to feel lethargic. I also had lower back pain and was lightheaded with bouts of dizziness. After discontinuing Repatha, it took 6 weeks to start to feel better. Repatha was very effective at reducing my cholesterol, but I could not handle the side effects. I just hope that I will eventually feel normal."

• Lau...
• Taken for 5 to 10 years
• December 6, 2024

"I have been on Repatha since 2016. Before Repatha, I had 5 heart attacks and a few angioplasties. Thanks to the cardiologist and Amgen for Repatha, my cholesterol stays down, my bad is good, and I haven't had another heart attack since 2016. So thank you for this medicine, Repatha and my cardiologist saved my life."

• kmc...
• Taken for 1 to 2 years
• June 18, 2024

"I was taking Repatha for about a year but started developing bruising so I stopped and started again after 3 months. Now my hair is falling out. I had thyroid and all sorts of blood work. Can’t determine if it's Repatha or cortisone injection that I had. I’m going to stop again and see if it stops falling out. Ugh! My cholesterol is great on the drug so hoping it's not the Repatha."

• San...
• Taken for 1 to 6 months
• June 30, 2018

"I am a 71-year-old male and in relatively good shape. I was working out and riding my bike 10-15 miles a day. I have chronic high cholesterol (300 overall). I cannot tolerate statins. I started taking Repatha on March 3, 2018. Shortly after the second injection, I developed sinus issues (bloody nasal discharge), headaches, muscle/joint pain, muscle weakness, arrhythmia, diarrhea, and severe debilitating back pain. I did not immediately make the correlation with the Repatha injections. I made an appointment with my GP, and he took me off Repatha. My last injection was May 13, 2018. The symptoms have improved but are still present. I only hope the side effects are reversible. The quality of my life has been significantly impacted. I am disappointed. Repatha did lower my cholesterol, but the side effects are hardly worth it. Research this drug before you inject it."

• shi...
• October 13, 2022

"Repatha is dangerous with muscle and joint, sinus, yeast infections, runny nose continue every day. The worst is muscle and joint after 6 injections in Oct. 2022. I quit, I would rather die. This should be reported. Do not take it, doctors lie to you."

• Tak...
• Taken for 6 months to 1 year
• August 31, 2018

"I have been on Repatha for about eight months because I cannot take statins. I have had some bad side effects: joint pain, back pain, and continuous sinus drainage. Can go to sleep, fatigue bad. High blood sugar. And I feel it has eaten my stomach lining out. I can't eat much of anything. I have been off of it for 30 days and hope and pray this medicine gets out of my system before 3 months. I will have to see if I can keep my cholesterol down with diet. This stuff feels like it is killing me. Would never recommend it at all."

• gil...
• Taken for 6 months to 1 year
• February 15, 2025

"Repatha worked for me when max dose statin seemed to do nothing for 10 years. Bad family history. Some blockage detected at 42 yo. After 1 year on Repatha, my cholesterol reduced 55% and LDL reduced by 72%."

• njb...
• Taken for 1 to 6 months
• August 30, 2017

"Took 3 shots of Repatha. OK after the first one, but after the 2nd and 3rd, I began to feel bad. Had back aches, soreness in hips and knees. Difficulty in climbing stairs. Blood work showed that it did lower my total cholesterol and LDL. However, I feel that this drug is not worth the serious side effects which I experienced."

• tru...
• Taken for 1 to 6 months
• April 29, 2016

"I had a heart attack and stent and have problems with taking statins. I have taken 4 injections so far. I have stomach cramps, and double over with pain, leg cramps unreal. I can tolerate Crestor 3 days a week. Had a check-up with my heart doctor, and he said to go off the Repatha. It will lower your numbers, but, as it states, and so did my heart doctor, that there is NO proof it will help your heart. I thought this strange, but, as he said, it also says that on the pamphlet that comes with it. I am quitting taking it, stomach aches and bowel problems are miserable."

• Ste...
• Taken for 1 to 6 months
• October 21, 2017

"I am 69 years old. I have been an athlete all my life and have run over forty thousand miles. I do not tolerate statins due to severe muscle pain. I was walking 6 miles a day prior to taking Repatha. After three shots of Repatha, I developed debilitating pain and weakness in my back and right leg. 9 on the pain scale. I still, three weeks later, have difficulty walking. It seems to be improving somewhat, with better days followed by a more difficult day. This has had a terrible impact on my quality of life. DO NOT TAKE this drug!"

• Ter...
• Taken for 2 to 5 years
• October 14, 2024

"I have read that people have terrible side effects. I have had a good experience. I had horrible side effects with statins, as my husband is fine with them. My HDL is amazingly low now. Started using Repatha after issues with statins after a 2019 stent in LAD. Every important medication seems to affect people differently. So, if you are not getting results, let your doctor try a few alternatives. Maybe you will find one that is perfect for you, maybe not. I am very happy with Repatha. Only minor thing is I inject into my thigh and sometimes get a bruise at the site, but that's user error as I need to learn better how to find the best spot."

• Min...
• March 8, 2019

"My mother took Repatha. If you are taking this medication, watch for memory loss, having a hard time walking, anything not normal. This medication just about killed my mother. From heart problems to liver. Her memory confusion started mild, along with the walking problems. She went from walking on her own to a cane to a walker. She is 3 weeks from the last shot, and finally, she can walk with the walker again, and yet she had been really bad last month and a half. Thought we were going to lose her. Please be careful with Repatha."

• RoB...
• Taken for 1 to 2 years
• January 3, 2020

"I have been plagued with high cholesterol most of my adult life. I have had three heart attacks, resulting in a total of 16 stents in my heart that all doctors attribute to high cholesterol. I had tried every statin drug available that really did little to control my cholesterol, but, other than red yeast rice, all had horrific side effects of pain and lack of muscle usage. Repatha, along with red yeast rice, has reduced my cholesterol to below normal averages. My doctor is ecstatic, which makes me happy to not be subjected to statins. At the most, I have experienced minor local pain temporarily after an injection and, on rare occasions, a bit of minor nausea for about an hour after an injection. Repatha truly has saved me from misery."

• CJa...
• November 9, 2019

"Family history of hypercholesterolemia. 34 y/o male. I've been taking 40 mg of Crestor for at least 7 years now, and the best it does is bring my total cholesterol down to the mid-250s. I am in good shape and work out at least three days a week. My cardiologist has been trying to get me to take Repatha for at least two years now. I was worried about all the side effects because I am usually the one getting the side effects. It is frustrating. Reluctantly, I started taking the biweekly injections over 6 weeks ago. I am blessed to say that I have had little to no side effects at all, other than a stuffy nose every now and then. I feel great. I'm waiting another month or so until I check my cholesterol panel again to give the medication time to work. I'm glad I got the courage and tried it out. Best of luck, everyone. Sorry to the people who have had a bad experience. Hope you get well and find an alternative to keep you healthy."

• Joe...
• Taken for less than 1 month
• November 11, 2022

"I had terrible experiences with statins, so my cardiologist suggested Repatha. I've had one dose and I'm done! I feel weak, feel like my head is in a fog, and have lost the vigor for life I had before I took this. My personality is blunted, as if I'm perpetually in need of sleep. I can't sleep all night anymore. Can't think clearly. I've never had a heart attack, but my doctor put me on this. According to the research, this only prevents 1 out of 100 heart attacks after 2.5 years of use. There's no way I'm going to take this again. I'll lose weight, watch my diet, exercise, and take my chances because this is a case where the supposed cure is worse than a 1 in 100 chance of getting the disease. Do your research about anti-cholesterol drugs."

• jhm...
• August 11, 2017

"Was going in for a heart cath, put on Repatha because I can't take statins. Dose 1, some diarrhea, mild back pain, and feeling like a kidney stone was trying to move. Dose 2, same feeling as dose 1, seemed a bit worse, wrist, knees, and ankles slightly swollen. Dose 3, two hours after injection, felt like my teeth were 3 inches tall, lost the use of my legs for 5 hours, joints ache and low back pain, 7 on the pain scale. Three days later, upper right quadrant pain, muscle spasms, hurt to walk, knees and feet felt like they were on fire. Nipples are painful, short of breath, and can't get enough sleep, tired all the time. Been to the ER, advised to discontinue Repatha. Been 45 days, still having severe back pain and very short of breath."

• D1M...
• Taken for 1 to 6 months
• July 16, 2024

"Both my wife and I had high cholesterol and were unable to take statins due to the painful side effects. She tried Repatha first and had virtually no side effects. I started it a few months after her and have also had no side effects. Her total cholesterol came down 72 points and mine down 50 points. Been on it for about 5 months. People have told me my face looks younger since I now have less bags under my eyes."

• Suz...
• October 20, 2019

"I took Repatha for high cholesterol. I had a heart attack in 2016 and struggled with statin drugs. I asked my doctor about Repatha and she said to try it, and I did. I asked about side effects, she told me there were none. I wonder why the doctors don't look into the medications that they give people, knowing the other problems people are having with their health. After the shot, I immediately felt like my tongue was swollen, but that passed. The next day is when the bad side effects started. I've been in the bathroom ever since that first shot with diarrhea. I've been in the emergency room. I have nausea and the chills on and off. I'm a diabetic, and it has raised my blood sugar. The thing I wonder about all medications is why don't the doctors know more so they can give you an honest, realistic answer about what might happen, so that you can make your own decision."

• Jur...
• September 25, 2019

"On Repatha for 2 years. Developed peripheral neuropathy, tremor, visual disturbances, intractable diarrhea, and muscle weakness on one side so profound that I could not lift my foot and needed a cane. Doctor found no other explanation. Off now for 4 months - neurological and gastric effects remain. Effective at lowering cholesterol, but at what cost?"

• Dis...
• Taken for 1 to 2 years
• November 15, 2019

"Been on Repatha. Had all symptoms of side effects with flu-like symptoms with aches and pains. Got sick last month, thought it was pneumonia, had a chest X-ray, showed something on lung, now PET scan and have a mass. That’s right, cancer that spread to my lungs. Bet it’s this damn drug since it causes respiratory infections. So when is Amgen Pharma and the FDA going to come out with this? They have reports on lung cancer. No doubt it’s the Repatha that caused my lung cancer. I was fine until I started this. It’s poison. You’re only a guinea pig."