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Evolocumab for High Cholesterol, Familial Heterozygous User Reviews (Page 4)

Brand names: Repatha

Reviews for Evolocumab

Commonly mentioned side effects
  • Ano...
  • Taken for 1 to 2 years
  • June 4, 2025

Evolocumab "Repatha 140 mg/mL autoinjector once every 14 days. Impressive results with lowering my cholesterol, but the serious side effects I experienced over time were not worth it. While I could deal with the eczema outbreaks, the debilitating joint pain and muscle weakness ended up being a deal breaker. I went from being an avid runner and martial artist to struggling to walk a city block without increasing pain, while needing to wear knee braces. I had been taking it for around two years, and my symptoms kept getting progressively worse, but I didn’t suspect it was the Repatha. Once I did suspect it, I quit taking it and started to regain some mobility after 10 to 12 weeks. After this phase, my doctor had me try it again to see if I would tolerate it. A week after the first dose, my symptoms returned, and I have been struggling with pain again. I won't take this medication again and hope the damage isn’t permanent. I’m a 57-year-old, formerly very active male."

3 / 10
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  • DRC...
  • Taken for 5 to 10 years
  • November 14, 2023

Evolocumab "Amazing medication that has helped drop my APO B cholesterol level to 36. Extraordinary results with no noticeable side effects. Previously placed LAD stent and now LDL down from 170 to 35 on combination therapy. Easy as can be to administer. Do not fear the injection as it is barely detectable."

10 / 10
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  • Spa...
  • Taken for 2 to 5 years
  • January 26, 2023

"I have had several heart attacks. Two open heart procedures with a total of nine CABGs/by-passes and five stents. Have been given three different statins with various physical side effects, and none of which reduced my total cholesterol below 270. Less than six months after using my Repatha SureClick, my cholesterol was reduced to 170. This is my second year of using this amazing drug. Within three days, I had a full lipid panel. My total cholesterol stands at 163. LDL is down and HDL is up. To me and my family, this has been a miracle drug."

10 / 10
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Frequently asked questions

  • She...
  • Taken for 1 to 6 months
  • July 22, 2023

Evolocumab "Extreme Dizziness Blurry vision Very low blood pressure Extreme Fatigue Cold ankles and feet Pain in right leg like buzzing and some cramps In the first two times taking it. An adjustment to my BP meds, diuretic, and ALL the symptoms went away. Looking forward to great results my next blood test saying my cholesterol is in a great range! BTW I take 140mg/ml injections once every 2 weeks. Very easy process."

9 / 10
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  • Ano...
  • Taken for 5 to 10 years
  • June 1, 2025

Evolocumab "I have used Repatha for 6 years. Previously, I tried stating, but could not tolerate them. My LDL when I started was 100, and now it is in the 40's. It is easily administered. I like the syringe best, but my pharmacy normally has only the SureClick autoinjector. It's okay. I prefer the syringe."

10 / 10
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  • Nol...
  • Taken for 6 months to 1 year
  • May 8, 2019

Evolocumab "Repatha caused me to get “drug-induced lupus,” so my life is forever changed and for the worse. I can only find one other person who had this reaction, but beware, it is possible."

1 / 10
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  • EZK...
  • Taken for 2 to 5 years
  • July 31, 2020

Evolocumab "I have been on Repatha for 5 years, my cholesterol is great, and I have had no side effects."

10 / 10
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More FAQ

  • Ray...
  • Taken for less than 1 month
  • April 11, 2017

Evolocumab "After taking the 2nd shot, I started having back pain, pain in my knees and hands. I can't take statins for the same reasons. I was hoping this was the drug without the pain."

2 / 10
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  • Tom...
  • Taken for 6 months to 1 year
  • April 13, 2025

Evolocumab "It helped a lot, but side effects are too heavy even after several months, so I stopped."

2 / 10
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  • Nei...
  • Taken for 1 to 6 months
  • January 16, 2019

Evolocumab "POISON. Flu syndrome immediately after one injection, followed by 8 months of muscle pain, cramps, and tightness, mostly in legs. Fatigue as well. No help from baclofen, diazepam, OTC pain meds."

1 / 10
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  • hr1...
  • Taken for 1 to 6 months
  • January 22, 2020

Evolocumab "I've been on the drug for 3 months, and it's been brilliant. No side effects and no issues. Just waiting for my first results back and hoping it has a big impact."

10 / 10
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24 Report
  • Lad...
  • Taken for 1 to 6 months
  • June 18, 2018

Evolocumab "Only took 12 doses and couldn’t move. Extreme fatigue and lethargy, back pain, and horrible leg cramps. Doctor has stopped for now."

4 / 10
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  • Okt...
  • August 27, 2017

Evolocumab "Took my 3rd fortnightly shot, and I will not take any more. The side effects are getting worse: back ache, muscle ache, runny nose, feel like I'm run down with a cold."

2 / 10
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  • Pja...
  • July 30, 2019

Evolocumab "I have been on Repatha for 14 months with absolutely no side effects and an incredible decrease in cholesterol. Game changer."

10 / 10
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22 Report
  • Ric...
  • Taken for 1 to 2 years
  • August 13, 2024

Evolocumab "Immediate reduction in cholesterol from 366 to 93 in two months. Statins did not work and caused side effects. Very easy to inject with no pain. I love Repatha."

10 / 10
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  • Luc...
  • Taken for 6 months to 1 year
  • April 11, 2020

Evolocumab "Since I am taking Repatha, my cholesterol dropped from 380 to 162 in the first 90 days, been on for six months, with no side effects. One time, little bruise on the injection site."

10 / 10
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  • Ger...
  • Taken for less than 1 month
  • June 23, 2024

Evolocumab "Raised blood pressure, raised sugar levels, and headaches, blurred vision."

8 / 10
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  • did...
  • Taken for 2 to 5 years
  • April 1, 2024

Evolocumab "Seems to be reducing my cholesterol. Constant runny nose is the only side effect. Very expensive so not sure I can afford to continue into retirement."

7 / 10
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  • Eri...
  • March 28, 2017

Evolocumab "Bad cholesterol at 48 (about 156). Total cholesterol at 148 and good cholesterol at 66 after 5 months with statins. It's amazing."

10 / 10
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  • Niz...
  • Taken for 1 to 2 years
  • December 13, 2023

Evolocumab "My cholesterol has become normal. I only have back pain as a side effect."

9 / 10
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  • Rea...
  • Taken for 1 to 6 months
  • June 30, 2024

Evolocumab "Muscle joint pain, Rheumatoid arthritis present, not sure if this medication is making it worse or causing independent pain. Unable to take statins due to muscle pain"

5 / 10
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  • Mar...
  • Taken for less than 1 month
  • April 25, 2023

Evolocumab "I reacted badly to Repatha. I was very ill for 3 days."

1 / 10
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  • MJG...
  • Taken for 2 to 5 years
  • November 21, 2022

Evolocumab "I have been on Repatha for 2 years, and my TC has dropped over 300 points. With no side effects. Easy injection every other week."

10 / 10
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  • Mik...
  • December 25, 2021

Evolocumab "After a heart attack, finally got on Repatha. Total cholesterol is below 100. Life changer in my life."

10 / 10
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3 Report
  • Dav...
  • Taken for 1 to 6 months
  • November 15, 2020

Evolocumab "This drug has helped me a lot. My LDL was down to 22."

10 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.