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Low-Ogestrel-28 and Mood Swings: What Users Say

Mood swings: mentioned by 12 users (17.6%)

Based on user experiences from 68 Low-Ogestrel-28 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 20.6%
weight gain 20.6%
acne 19.1%
cramps 17.6%
mood swings 17.6%
anxiety 11.8%
sexual dysfunction 10.3%
depression 8.8%
headaches 8.8%
bleeding 7.4%

Reviews for Low-Ogestrel-28

Commonly mentioned side effects
  • TRa...
  • Taken for 1 to 2 years
  • January 27, 2013

For Birth Control "These are my first birth control pills. I had heard about the weight gain and such, but it never happened to me. I am really happy with the pill. During my pre-pill life, I had cramping and lots of gas and mood fluctuations during periods, but during this pill, I have very predictable periods and almost no mood imbalances or unusual pain. Since I work out regularly, I experienced no weight gain at all."

8 / 10
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  • Jen...
  • Taken for 6 months to 1 year
  • August 7, 2018

For Birth Control "I started this pill back in February, and for the first couple of months, I was fine-no side effects. And if you’re looking for a pill to regulate your period, this one works wonders. I never got breakthrough bleeding either. However, after the first couple of months were over, I slowly started getting into a funk. My mood is just “numb” all the time, and I never want to get out and have fun anymore. My anxiety is a 10 when it was usually a 4. Now I know everyone’s bodies are different, so they’re going to react differently to this medication, but I can’t stand not being able to focus or, like... be happy. I’m getting off of it finally and switching to another type, so wish me luck. Side note: this birth control also does its job in the pregnancy prevention category VERY well if you take it on time. I never had to worry on this pill."

5 / 10
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12 Report
  • Sum...
  • October 28, 2013

For Birth Control "After being on Tri-Nessa for at least a decade with no problems, I was switched from Tri-Nessa to Low-Ogestrel because I was experiencing very heavy bleeding during my periods. The Low-Ogestrel did fix the heavy bleeding but at a cost. I've been on L.O. for 6 months and have been experiencing depression, mood swings, acne on my chin, and pimples on my scalp. At first, I attributed these things to the beginning of menopause, but after really thinking about it, it just seemed too coincidental that these things began when I began taking a different pill. This morning, I googled 'side effects of Low-Ogestrel' and am finding pages of stories just like mine. I already have a call into my Dr. and will switch pills."

4 / 10
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15 Report
  • Dar...
  • Taken for 6 months to 1 year
  • July 6, 2016

For Birth Control "I've been on these for 6 months. I'm a very petite person, and ever since I was 17, I've had crazy bad cramps and acne. I've tried a few different kinds of pills, but the Low-Ogestrel-28 pills made me sick. Cramps never went away and even got worse. My acne got good within a few months, but then got bad again. My sex drive has decreased, and I hate that. It also has messed with my hormones, and I'm already emotional, so I'm ten times more upset when I don't need to be. I don't have a good appetite anymore, and it makes me more sick. It also made me throw up when I take them too late. My period goes from 4 days to 2 days, then a week, it's all over the place, and I would like a steady cycle. So, in all, these pills are too over the place, not really helpful."

2 / 10
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10 Report
  • wd1...
  • Taken for 1 to 6 months
  • February 14, 2016

For Birth Control "I got switched to this pill because I was beginning to have severe cramps on my Lutera pill. I liked this pill for the first 3 months as I noticed my boobs grew, my acne completely cleared up, and my cramps were gone. However, during this time period, I noticed about a 10 lb weight gain that only occurred while I was on the pill (I lost 8.7 pounds while on my sugar pills one week). I also noticed that I was really emotional and got upset about everything, and I never cry, ever. I know everybody has different reactions to medications, but I would suggest not even trying this pill because the pros were not worth the cons."

3 / 10
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8 Report

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  • Anonymous
  • Taken for 6 months to 1 year
  • August 4, 2018

For Birth Control "I have been taking this pill for 7 months. The first 3 months were the worst as my body was adjusting, and I was so bipolar and nauseous. Now... it honestly worsened my acne from mild to moderate, painful cysts. No weight gain. But honestly, this pill has left me an emotional wreck. If I'm not angry, I am sad or easily irritated. Happiness is rare. And I break out even worse during my period in places I never even broke out before. Not the worst, but not the best. Definitely switching pill brands."

7 / 10
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5 Report
  • Kat...
  • Taken for 1 to 6 months
  • December 3, 2019

For Birth Control "Stay far away from Low-Ogestrel-28, that is all I can say. This birth control has made me the most unhappy human being. I cry at random times, my mood swings are unreal, and I’ve gained so much weight. I’ve also started getting acne. I am switching asap."

5 / 10
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5 Report
  • the...
  • Taken for 10 years or more
  • June 9, 2019

For Birth Control "I was on this pill from age 21 to age 31. After concerns of hypertension, my doctor inserted an IUD (Liletta). I gave it a go, loved the idea of not having a period or having to take a pill every day. After 5 months of insane mood swings, nipples so sore if I even looked at my breasts, there was a surge in pain, yeast infections, and a 10-pound weight gain with no decrease in blood pressure, I'm very happy to be back on the pill. On the Low-Ogestrel-28 pill, my periods are very regular and predictable. They last about 5 days, only 3 of those with significant flow. I have had no problems losing weight on it, no acne, no mood swings, or headaches. Starting back has been a shock to my body, as I've been on my period for about 12 days now, but that kind of thing is to be expected when you switch birth control methods. Just started placebo week for the first time since the IUD removal, and I honestly feel like a different person. I love this pill, never going back to an IUD."

10 / 10
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2 Report
  • All...
  • Taken for 1 to 2 years
  • December 12, 2019

For Birth Control "Low-Ogestrel-28 was the first birth control I used. In the first few months of taking it, my mood swings were off the charts. Crying one minute, happy the next. I did not gain weight, nor did I experience any acne. My cup size went from an A to a C, and it did its job keeping me from getting pregnant. I have been on Low-Ogestrel for a year now but have recently switched to Sprintec. I switched because my periods became irregular on Low-Ogestrel. Some months I would have heavy bleeding during the active pills, then extremely heavy bleeding during all of the placebos. I went to my doctor, and she prescribed me a higher hormone dosage pill to correct that. I had extremely heavy periods before going on birth control, so the low hormone dosage in Low-Ogestrel wasn’t enough. If you have heavy periods and are thinking about going on Low-Ogestrel, don’t, and get a higher hormone dosage pill so you can have normal bleeding."

7 / 10
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2 Report
  • Alc...
  • Taken for 1 to 2 years
  • September 19, 2017

For Birth Control "Was on it for about a year and 2 months. Experienced no weight gain or mood swings. My acne was not severe by any means, but it did flare the first month I started taking Low-Ogestrel, which went away the next month. Still get occasional pimples closer to my period. Had to switch because after about 11-12 months I started spotting during the active pills, which turned into full-blown periods that would last for 2 weeks. Tried to ride it out because my doctor suggested it might be a hiccup, but it continued for two more months. Was bummed because I loved this birth control."

9 / 10
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  • Rlt...
  • Taken for 6 months to 1 year
  • September 2, 2017

For Birth Control "My pharmacy used this brand and Crycelle interchangeably, but both were generally the same thing for me. I gained a lot of weight on Depo before this, and though I haven't gained more on this pill, I haven't been able to lose much weight on it either. My face isn't necessarily breaking out, but my cheeks have been red with little bumps almost like rosacea since starting this brand. It isn't constant but does flare up sometimes. The only really bad side effect I've noticed is I've gotten really bad anxiety and mood swings. It is still way better than how I felt on Depo, and the birth control is really cheap ($15 per pack), so I will stick with it until I have money to try other brands."

7 / 10
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  • Anonymous
  • June 16, 2008

For Birth Control "I have tried several different birth controls. They all gave me major mood swings. This birth control is the first one that I have been able to take successfully."

10 / 10
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24 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.