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Low-Ogestrel-28 and Depression: What Users Say

Depression: mentioned by 6 users (8.8%)

Based on user experiences from 68 Low-Ogestrel-28 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 20.6%
weight gain 20.6%
acne 19.1%
cramps 17.6%
mood swings 17.6%
anxiety 11.8%
sexual dysfunction 10.3%
depression 8.8%
headaches 8.8%
bleeding 7.4%

Reviews for Low-Ogestrel-28

Commonly mentioned side effects
  • Sum...
  • October 28, 2013

For Birth Control "After being on Tri-Nessa for at least a decade with no problems, I was switched from Tri-Nessa to Low-Ogestrel because I was experiencing very heavy bleeding during my periods. The Low-Ogestrel did fix the heavy bleeding but at a cost. I've been on L.O. for 6 months and have been experiencing depression, mood swings, acne on my chin, and pimples on my scalp. At first, I attributed these things to the beginning of menopause, but after really thinking about it, it just seemed too coincidental that these things began when I began taking a different pill. This morning, I googled 'side effects of Low-Ogestrel' and am finding pages of stories just like mine. I already have a call into my Dr. and will switch pills."

4 / 10
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15 Report
  • Jul...
  • Taken for 1 to 6 months
  • March 10, 2022

For Birth Control "Great birth control, but made me extremely fatigued. Couldn’t get out of bed for nothing, might’ve made my depression worse, but idk because it could’ve just been the not being able to do anything and feeling like a vegetable. Didn’t see many reviews saying this, so I'm not sure how it would affect every person."

5 / 10
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3 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • August 4, 2018

For Birth Control "I have been taking this pill for 7 months. The first 3 months were the worst as my body was adjusting, and I was so bipolar and nauseous. Now... it honestly worsened my acne from mild to moderate, painful cysts. No weight gain. But honestly, this pill has left me an emotional wreck. If I'm not angry, I am sad or easily irritated. Happiness is rare. And I break out even worse during my period in places I never even broke out before. Not the worst, but not the best. Definitely switching pill brands."

7 / 10
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5 Report
  • Bet...
  • November 10, 2020

For Birth Control "I was on Low-Ogestrel-28 for about 9 months before my family basically had an intervention with me and told me I had to switch to something else. It wasn't until about month #6 that I really started experiencing the bad symptoms like depression, anxiety, suicidal thoughts, and anger/mood swings. I also saw increased appetite, bloating, water retention, and 10 lb weight gain. I was crying, lashing out, and overly emotional. I finally called my ob-gyn, and I got switched to the mini pill, and I feel 100% myself again. I feel like I'm on nothing. I came to the conclusion that estrogen and my body just don't do well, no matter what brand of combination pill. This pill has big-time side effects on me and messed with me psychologically. I noticed a drastic change 1 month off of them already, like I'm mellowed out and relaxed. This pill landed me in therapy because I couldn't control my anger. As a side note, it 100% did its job, which was to prevent pregnancy."

3 / 10
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3 Report
  • blb...
  • Taken for 1 to 2 years
  • March 4, 2022

For Birth Control "I was on Low-Ogestrel for about a year and a half after getting married. I experienced about 30 lbs of weight gain, moodiness, anxiousness, and overall felt depressed. I stopped birth control in May of 2021 after my husband and I decided we wanted to start trying for a baby. I have always had regular periods. It took 2 months for my period to come back, and now I believe I have pill-induced PCOS. I get a period every other month, and we have been trying for about 5 months now, and no luck. We have started seeing a fertility doctor and are getting bloodwork done to see what next steps we can take. I definitely do not recommend any form of hormonal birth control if you plan to start a family down the road. Looking back, we both seriously regret the pill and wish we had gone with natural family planning instead."

2 / 10
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1 Report
  • Nic...
  • Taken for 1 to 6 months
  • August 30, 2018

For Birth Control "I had my period for a month straight after taking this for a couple of weeks. Then, when that was finally done and I got my period again the week before, I was extremely bloated and constipated. I have had no sex drive, when my boyfriend tries to be physical with me, I get disgusted, and my anxiety and depression have been horrible. Along with that, I have nausea almost every time I eat. I've been miserable. Worst birth control I have ever taken."

1 / 10
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6 Report

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