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Tri-Estarylla and Weight Gain: What Users Say

Weight gain: mentioned by 15 users (17.0%)

Based on user experiences from 88 Tri-Estarylla reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

depression 29.5%
mood swings 29.5%
anxiety 26.1%
acne 18.2%
weight gain 17.0%
nausea 15.9%
cramps 14.8%
bleeding 13.6%
fatigue 11.4%
bloating 10.2%

Reviews for Tri-Estarylla

Commonly mentioned side effects
  • Tra...
  • Taken for 1 to 6 months
  • June 17, 2021

For Birth Control "I had been taking Tri-Sprintec for the past 2 years, then suddenly I started to get Tri-Estarylla. Don't know why. They seem to be the same medication, but they are not. This medicine made me gain 10 pounds in 1 week, I had bad cramps and overall fatigue. I wish to have my Tri-Sprintec back. Don't take this medicine, from my experience, it was horrible. I'm stuck with all this weight now."

1 / 10
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15 Report
  • Ano...
  • Taken for 1 to 2 years
  • July 14, 2019

For Abnormal Uterine Bleeding "I was taking this pill on and off for irregular periods between the ages of 15-17 (I am 19 now and recently discovered I have PCOS). While it regulated my periods, man, the side effects were awful! I was depressed to the point of feeling like I was in a dark, dark hole, my anger was out of control, and I gained 40 pounds. There are much more effective pills with fewer side effects out there - glad I switched!"

3 / 10
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4 Report
  • Anonymous
  • Taken for 1 to 6 months
  • December 7, 2022

For Birth Control "I absolutely do NOT recommend this birth control. For some reason, my doctor's office switched me to this without even asking me. I immediately noticed that I started breaking out where, as I never did on my old birth control, Ortho. I gained weight for no reason, and my diet and exercise did not change. I also started feeling EXTREMELY lethargic and low energy despite getting more/better quality sleep, eating good foods, and exercising. It was like nothing I did was preventing me from gaining weight and feeling like rubbish! My periods were all over the place and did not lessen, either. I waited for the 3-month prescription to be up and immediately asked my provider to switch me back to what I was on previously."

2 / 10
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3 Report

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  • Rae...
  • Taken for 1 to 6 months
  • February 27, 2018

For Birth Control "My experience with this drug has actually been pretty good. I did have mild acne breakouts and some bloating and water weight gain. These all went away pretty quickly, though. The only major side effect I've had is significant bleeding between periods. However, I had fewer and lighter cramps and no ovarian pain like I dealt with before, and no depression/mood swings or any of the other side effects that other users have experienced."

8 / 10
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3 Report
  • Lad...
  • Taken for 1 to 6 months
  • March 3, 2020

For Birth Control "Literally, I got pregnant right away taking this pill, which was recommended by Pill Club (sadly). I was taking Sronyx before, which unfortunately gave me a lot of breakouts, and it made me very nauseous, so I decided to give this a try, and boom, I'm pregnant. This pill did help me clear my skin, but I noticed a lack of sex drive, and I noticed I seemed more bloated and gained weight a little in only a month! Definitely, I do not recommend this pill!!"

1 / 10
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5 Report

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  • mka...
  • Taken for 1 to 6 months
  • January 12, 2023

For Birth Control "I was originally on a Lupin brand under the name norgestimate and ethinyl estradiol. I got my prescription from Walgreens pharmacy, but they were not partnered with that manufacturer, so I was put on Tri-Estarylla. I had terrible anxiety and bloating all the time. I gained 10 lbs within those two months, and I just don’t feel like myself. I will stop this and try another brand. Birth control affects everyone differently, and you may find this brand might be good for you."

3 / 10
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1 Report
  • Xan...
  • Taken for 1 to 2 years
  • August 22, 2019

For Birth Control "I was on Tri-Estarylla for over a year. It was my first birth control. I am a high-testosterone person with a high iron count as well. Before taking Tri-Estarylla, I had issues with acne (chest and cystic acne on my back and cheeks), fatigue, mood swings, body hair, and fluctuating weight. My periods were light, 4 days, and I never had cramps. After taking Tri-Estarylla, my acne cleared up, and my facial and chest hair virtually disappeared. However, my period became heavier, 7 days, and I experienced cramping. The biggest concern I had was that I gained 30 lbs in a year. Before BC, I never had problems with losing weight when necessary, but this post-BC weight is stubborn. Also, I experience intense anxiety episodes where I didn't before. I have more energy, but no motivation. Birth control-wise, I've never had a pregnancy scare, despite the fact that I do get lazy with the timing of my medication, but that's on me. I just wanted to share my experiences with side effects. Best of luck to y'all!"

7 / 10
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3 Report
  • Ter...
  • Taken for 2 to 5 years
  • June 21, 2022

For Birth Control "I started taking this as a generic replacement for my original prescription 3 months into trying birth control to regulate my period. Previfem wasn’t too bad, but I did notice a lot of changes. When I got Tri-Estarylla instead, I just assumed it had a similar adjustment period. However, I’ve been on Tri-Estarylla now for two years and 3 months. Since starting this medication, I’ve become depressed, anxious, constantly nauseous, constantly tired, and constantly having headaches of varying severity. There were many days when I would avoid driving because my headaches were so bad that I had problems seeing and focusing. I have also gained 38 lbs during this time, which has not helped at all with all the other issues this drug caused. I’ve become an emotional mess with mood swings that make no sense at all. After taking it, I cry out of nowhere, for no reason at all. Everyone is different, but I do not recommend. I followed instructions to a T and never skipped a day."

1 / 10
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1 Report
  • Kri...
  • August 29, 2017

For Birth Control "Contrary to the negative reviews on this birth control, I actually had a pretty positive experience. I had great skin, my periods were very regulated and short, I had some weight gain (I am skinny and did want to gain weight, so if you don't want weight gain, I wouldn't suggest this). I think I only experienced mood swings during the first few months of taking this. I also experienced some migraines, but those only lasted 2-3 months as well. I was always bloated, but I'm not sure if that was due to the birth control or if it was just my diet. The only other thing I didn't like was that this gave me a very low sex drive. I usually had a higher sex drive the week of the sugar pills, so I assume this is because of the birth control."

8 / 10
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2 Report
  • Awf...
  • Taken for 6 months to 1 year
  • January 5, 2022

For Birth Control "I was switched onto Tri-Estarylla from Tri-Sprintec (which was generic for Tri-Previfem) for whatever reason. The pharmacy didn't tell me, but I assumed it was a rebrand and the same thing as Tri-Sprintec, but it is NOT the same. Tri-Estarylla has been awful for me. Very depressed, withdrawn, lethargic, and severe weight gain, like 20 pounds weight gain. The weight gain adds to the depression too. And I eat fairly healthy and exercise 5-6 times a week, but the weight kept going on no matter what I did. I don't like this pill, and I have requested my doctor and pharmacy to make a note to never replace Tri-Sprintec with this Tri-Estarylla ever again. This pill prevented pregnancy and lightened my period, but I am so unhappy with the weight gain and tiredness I experienced. I get to go back on Tri-Sprintec now thankfully."

3 / 10
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1 Report
  • Tmg...
  • Taken for 1 to 6 months
  • January 26, 2021

For Birth Control "The past 3 months, I was switched onto Tri-Estarylla from Tri-Sprintec for what reason I still don't know. But Tri-Estarylla was awful for me. Bad cramps, severe weight gain (well, water retention I've come to find out). That last month was so awful I cried a lot, was very emotional, feeling of disconnect because of weight gain, and I was not very happy. This experience was a total 180 from Tri-Sprintec."

2 / 10
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2 Report
  • Jam...
  • Taken for 1 to 6 months
  • November 8, 2021

For Birth Control "Switched from the generic form of Junel 1/20 (was on it for 6 months). I've been on Tri-Estarylla for about 2 months now. So far, no significant side effects besides bloating and weight gain (that could be a new relationship though, lol). Junel 1/20 gave me intense side effects such as acne/rash, depression, mood swings, loss of sex drive, bloating 24/7, and breakthrough bleeding for 2 out of 4 weeks a month. With Tri-Estarylla, my period is heavier though and lasts 4 days mid-placebo pills with cramps starting the last week of active pills all the way through the end of the placebo week. Haven't seen much improvement in acne, but I haven't been on it for too long to see that. My sex drive has improved, and I haven't had any breakthrough bleeding or mood swings. My discharge is much heavier/thicker, but it's white and not dark brown like with my last birth control. No pregnancy scares, and this is the only form of birth control my partner and I use."

9 / 10
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  • Lex...
  • Taken for 1 to 6 months
  • March 8, 2025

For Acne "I'm on my 2nd pack. I am mainly on birth control to clear my skin. Since I have started, my acne on my face has gotten so much worse, especially around my mouth and chin. Cheeks are worse too. Trying to be patient because I've read it can take 3+ months to clear acne. It's just a little discouraging. I will say, I haven't gained weight or had breakthrough bleeding!"

6 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • February 4, 2022

For Birth Control "I haven't had any problems on this birth control. I have gained weight, but I don't know if that is related to the birth control since they usually change them up depending on pharmacies, but lately, it has been Tri-Estarylla. I've never had any mood swings or loss of sex drive from this! I've also never had any abnormal bleeding."

9 / 10
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  • Bra...
  • Taken for 6 months to 1 year
  • June 8, 2019

For Birth Control "These Tri-Estarylla are terrible birth control pills. I had to switch to these because my insurance changed and covered them and not my old ones. Within a year, I gained 15 pounds, I look bloated and not like myself. I haven’t changed my diet or lifestyle in any way. I’ve also been suffering crippling anxiety. Just got off them 2 weeks ago and feel so much better. Beware of this one!!!! I regret ever getting on them without prior research."

1 / 10
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