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Estradiol for Postmenopausal Symptoms User Reviews (Page 3)

Brand names: Estrace, Estradiol Patch, Dotti, Estrogel, Vivelle-Dot, Divigel, Lyllana, Climara, Femring, Minivelle, Delestrogen, Evamist, Estraderm, Depo-Estradiol Alora Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 5.6 out of 10 from a total of 412 reviews for the treatment of Postmenopausal Symptoms. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Estradiol

  • Hot...
  • Taken for 2 to 5 years
  • November 8, 2015

Vivelle-Dot (estradiol) "Worked wonderfully for my mood swings, hot flashes, night sweats, and sleepless nights. Used it for 4 years. Now I have been off for 2 months and can't stand the reappearance of all those nasty menopausal symptoms. I may have to go back on it."

10 / 10
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73 Report
  • June
  • Taken for 1 to 6 months
  • April 23, 2020

Estradiol Patch (estradiol) "I had the Sandoz patch, and it was great - a nice, thin patch that I forget is there except that I feel much better. The next month, I got the Mylan patch that is covered by my provider. It is thicker and catches just a little bit on the edges. More importantly, it leaves red marks underneath upon removing it and small marks that look like burns around the edge. I've also seemed to have some itching around the patch while it is on. I will be switching back to Sandoz."

8 / 10
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41 Report
  • marllam
  • Taken for less than 1 month
  • June 6, 2021

Dotti (estradiol) "My drug store replaced my Estradiol patch with Dotti. The first night, my restless sleep and dreaming. Daytime, I was cold and couldn't get warm. The second night, I experienced terrifying nightmares, woke up drenched in sweat two times. I was frightened, didn't know what was wrong with me. Figured it out! Another drug store was able to fill my regular prescription, and I was fine within a few hours. I question if this drug passed trials as a replacement for Estradiol."

1 / 10
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33 Report
  • SusyQ
  • Taken for 1 to 6 months
  • May 15, 2020

Estradiol Patch (estradiol) "This patch is so frustrating. It only stays on a couple of days because the material it is made of allows the water to soak in when you shower. Then the skin stays wet underneath and starts smelling sour. The adhesive on the edges irritates my skin and causes itching. What good is it if I can only get about 3 days out of it? I used to use a thinner patch made out of a different material, and I never could tell I even had it on, but the company quit producing it."

8 / 10
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40 Report
  • smile...
  • Taken for 10 years or more
  • November 3, 2017

Vivelle-Dot (estradiol) "I have used the patch for nearly 30 years after total hysterectomy (first patch discontinued and switched to Vivelle-Dot approx 10 yrs ago). I have tried going off and feel it's not worth the agony. Have looked for generic but have found none that really are the same although I see in the posts Sandoz recommended by someone, so may try again. Vivelle (at least when on Medicare) is very expensive with little or no coverage and if any copayment must jump through hoops---very discouraging. This is the only medication I use and at 72 feel great other than payments for this, but justify good health comes at a price!"

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56 Report

Are you taking this medicine?

  • Dish
  • October 26, 2016

"I started with perimenopause symptoms at 45 years old, beginning with heart palpitations and mild hot flashes. Shortly thereafter, all hell broke loose. Night sweats, hot flashes, crying, major insomnia, and an 18-pound weight gain in less than one year. I had no quality of life, so I went on the estradiol patch. I now feel human. Sleeping great and no night sweats. An occasional hot flash, but I can live with that. I went off for about a year, and almost everything came back with a vengeance. I'm back on!"

10 / 10
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62 Report
  • Lili
  • Taken for 1 to 6 months
  • February 20, 2021

Estradiol Patch (estradiol) "My biggest concern is that I am not getting the relief of post-menopause even though I am using a 0.1 mg patch because the patch does not stay on my skin. I have been using the estradiol patch for many years. I was using Vivelle Dot until it was not covered by my insurance and switched to Mylan Labs. It would be nice if these patches could stay on my skin to rate the effectiveness of the medication."

2 / 10
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34 Report
  • tania
  • May 6, 2015

"Brilliant, was having low mood, terrible hot flashes where I didn't want to venture out the door!! By fights with hubby! Mood has improved. Hope to keep on this long term. I had a hysterectomy at 41, refused to take it because of the cancer risk at first, but my symptoms were awful so I decided the benefits outweigh the risks."

10 / 10
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69 Report
  • Not...
  • Taken for 1 to 6 months
  • October 5, 2021

Dotti (estradiol) "Dotti 0.05 patch claims to be equivalent, but the stated amount of estrogen is less than the estradiol 0.05 patch. Six weeks after I was switched to Dotti by a pharmacy, I had horrible symptoms. Went back on the estradiol patch, and I am better. Safeway, Humana, and Costco are all using the Dotti patch. This patch should be pulled from the market."

1 / 10
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29 Report
  • Salim...
  • Taken for less than 1 month
  • August 26, 2022

Estraderm (estradiol) "Horrible! Like having a cheap crisp packet stuck on your skin - except they don’t stick! Crinkly - sounds like you’re wearing a nappy! Itchy, uncomfortable and pathetic adhesion. Not sure if the actually help with symptoms as my anxiety and rages are raised by the awfulness of using these patches! No more!"

1 / 10
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22 Report
  • lrond...
  • Taken for less than 1 month
  • February 4, 2024

Estradiol Patch (estradiol) "I am in perimenopause and started having horrible hot flashes 4 months ago. 10 a day at least. Crazy fluctuations between hot flashes and cold chills and shivering. Night sweats at night. Was miserable. Finally found a GYN who is current with the research and she prescribed the patch and progesterone pills. She initially prescribed a brand name 2x a week 0.05 patch. Well the manufacturers are all discontinuing making the brand name patch because the patent is up and insurance will only pay for generic. Furthermore, there is a patch shortage nationwide, so there was only one generic available - Mylan. I Googled and read not so pleasant things and was super freaked out but had no other options, so I tried it. After one week, I noticed I had fewer hot flashes. After 2 weeks, I had ZERO hot flashes. OMG, what a relief. It’s wonderful not to have crazy temperature changes all day and night. Yes, it irritates my skin, but the patch has a lot fewer risks than pills, so it's okay."

9 / 10
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9 Report
  • Lily
  • July 4, 2016

"I tried to wean off my other not-so-effective hormone pills but suffered terrible backlash. So, I went to see a different and more experienced OBGYN doctor and began applying Estradiol 0.05 coupled with Progesterone 100MG treatment. It takes about 10 days to see the full positive results. I am almost one month into this treatment now, and it has stopped hot flushes, I sleep through the night, stopped horrible stress attacks, stopped near-fainting temperature surges, my facial skin looks tighter and younger, and strangely, it makes me think about the birds and the bees. Knock on wood, I hope this medicine works for me for a long time to come. I am 64 years old, 5'3'', weight 126 lbs. Use an alcohol wipe and dry skin before applying the patch, it sticks better."

10 / 10
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60 Report
  • Suz
  • August 19, 2013

Evamist (estradiol) "Have been on it for 2 months, was getting hot flashed all day long. Night sweats even worse. Within days after starting the medicine, they pretty much stopped! No more on and off with my fan - sleeping through the night! And now, I ran out and haven't had it in 5 days (need to call for a refill prescription) and it's all BACK. Covers off and on all night long. This REALLY works for hot flashes!"

10 / 10
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74 Report
  • Lday...
  • Taken for less than 1 month
  • June 16, 2016

"I have been on this 1 mg pill a day for 1 month. I could not stand my mood swings, irritable, my husband said I was a completely different person, just after a month. My insurance does pay. I only have to pay 8 dollars a month for it my husband said he would pay 100.00 dollars for it lol plus I have lost weight on it also very happy with it saved my marriage."

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58 Report
  • Anonymous
  • Taken for less than 1 month
  • September 2, 2020

Estraderm (estradiol) "Estraderm MX 25. These patches are terrible. They don’t adhere to the skin! After one day, it comes off. I normally take Estradot 25, but it is sold out across the state and unavailable! Not impressed... and I’ve been getting hot flushes again..."

2 / 10
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34 Report
  • Hot...
  • Taken for 1 to 6 months
  • August 8, 2019

Estradiol Patch (estradiol) "I was using Vivelle Dot and then Minivelle for 10+ years. Due to the cost and no insurance, I switched to the generic patch. It does NOT work. The change in my estrogen levels was drastic... as if I wasn’t getting any at all. The hot flashes and night sweats returned. These patches are trash. I will be paying the outrageous price for Minivelle to get my hormones balanced again."

1 / 10
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40 Report
  • Tee
  • Taken for 1 to 6 months
  • October 7, 2019

Climara (estradiol) "I recently was prescribed the 0.25 patch Climara, and it has really helped my symptoms a lot. I was worried about the patch not sticking after reading several reviews, so after I apply my patch, I place waterproof tape to hold it in place, and I have never had any problems. I place mine on my upper buttock and switch sides when it's time for a new patch. It's totally free, and you can use it instead of your insurance. My Climara with insurance was close to $100. With a coupon, it was $33. I go for a checkup in a few weeks, but I feel that my gyn will increase my dosage to head off a few new symptoms. The peeling off of the patch can be difficult at times, but I remain patient and take my time. Good luck, ladies! Hope everyone finds relief."

10 / 10
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39 Report
  • Anony...
  • Taken for 2 to 5 years
  • October 27, 2021

Femring (estradiol) "Femring 0.1 is the only thing that has really worked for all my symptoms, especially moodiness, depression. After trying everything else, I was so pleased to find it. However, it definitely doesn't last for 90 days. I've noticed the past year it has lasted 8 or 9 weeks at most. This round it lasted 6 weeks, and I immediately know when it's not working. I literally feel terrible overnight - hot flashes, irritable, depressed, food cravings. I'm desperate to somehow stockpile it! I wish the company making it could address this. But like so many women's health issues, it's not that important to anyone but us."

10 / 10
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26 Report
  • Angus...
  • Taken for 1 to 6 months
  • October 31, 2013

Vivelle-Dot (estradiol) "I have been experiencing hot flashes for 3 years, but I could take it no more. I finally caved and asked for the hormones! My doctor prescribed the Vivelle Dot at 0.05, and 3 weeks later, I called and asked when I could expect some relief from these awful hot flashes. It had cured my sleeping issues, and my sex drive came roaring back, and my dry skin improved, but nothing in the hot flash department. It was increased to 0.075, and still no relief from these massive meltdowns. I am getting very upset that I can get no relief and can't wait to see my doctor again next month. I hate to have another increase but am wondering if it will finally help!"

5 / 10
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69 Report
  • Suz
  • Taken for 1 to 6 months
  • March 1, 2023

Dotti (estradiol) "My pharmacy changed to Dotti brand manufacturer the end of November 2022. I loved how the estrogen patch was smaller and less visible. However, my postmenopausal symptoms started back within three weeks of beginning the Dotti patch. I had increasing hot flashes, dry skin, brain fog, and fatigue. I scheduled an appointment with my OB/GYN in February to have my hormone levels rechecked. She discovered I had almost NO estrogen in my system. NONE. She said my body was not absorbing the medication. However, I have not had problems absorbing any other brand over the last 4 1/2 years. The Dotti brand estrogen patch was useless for me. I had to switch pharmacies to use a different manufacturer."

1 / 10
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16 Report
  • Rhonda
  • Taken for 1 to 6 months
  • August 25, 2021

Dotti (estradiol) "I had been on another estradiol patch for about a year. My husband's employer requested we start using a mail prescription, and when we did, they switched me to Dotti patches. I started wondering why I was feeling crabby and irritable again, sort of like I did before taking the patches. Also, I’ve been gaining weight. Not sure if that is also from the patches. But I’ve requested switching back to my original patch. I still wasn’t sure if this was because of the Dotti patches, but after reading these reviews, I’m sure of it. Would not recommend."

1 / 10
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26 Report
  • primad
  • October 2, 2008

Evamist (estradiol) "I haven't seen much mentioned about the personality change (i.e. edginess and sometimes just plain meanness) that occurs with perimenopause. I have found that using this spray, it takes that edginess away. My family can tell when I forget to spray it in the morning. I don't like being mean, my nature is typically laid-back and normally a nice person. It has been a big help to me and my family by giving the nice mom back to the family."

10 / 10
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89 Report
  • dawnc...
  • Taken for 1 to 6 months
  • August 15, 2012

Divigel (estradiol) "After a surgically induced menopause, the onset of hot flashes and night sweats was so fierce, I asked my nurse practitioner what works. She mentioned Divigel. I started on the lowest dose and actually felt like myself again within one week of use. Keeping in mind that you want to stay on the lowest dose possible, she reminded me that this is to cut down only on the severity of those hot flashes, not get rid of them entirely. I am so happy on this HRT. Just apply to your upper thigh once daily and that's it!"

10 / 10
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72 Report
  • Ali
  • Taken for 1 to 6 months
  • October 9, 2020

Estradiol Patch (estradiol) "I have been on Vivelle Dot for 8 years. Love it and no issues at all. I cannot find it anymore and have checked several pharmacies. I had to switch to Mylan generic. Absolutely awful. It does not stick well and comes off. It leaves red marks on my skin and is itchy. I do not feel I am getting the same amount of hormones, and my body can tell the difference. I have used it for 2 months. The patch is supposed to last 3 1/2 days, and I am sometimes changing after 2 days. Not happy with this. I hope to find Vivelle again. I am looking for other options."

3 / 10
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31 Report
  • Gess
  • Taken for less than 1 month
  • December 17, 2020

Estraderm (estradiol) "Has anyone experienced that the Estraderm patch does not stick to the skin? It's driving me crazy. Even though I clean the skin with medical swab wipes, wait for the area to dry, and it still doesn't stick."

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30 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.