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Dotti and Insomnia: What Users Say

Insomnia: mentioned by 7 users (15.9%)

Based on user experiences from 44 Dotti reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 29.5%
mood swings 18.2%
insomnia 15.9%
irritability 13.6%
night sweats 11.4%
depression 9.1%
fatigue 9.1%
headaches 6.8%
nausea 6.8%

Reviews for Dotti

Commonly mentioned side effects
  • Pit...
  • Taken for less than 1 month
  • April 11, 2023

For Postmenopausal Symptoms "This experience has been extremely unpleasant. All of my cardiac, vaginal, urinary, sleep, agitation, and hot flash symptoms have returned. I strongly believe that this medication should not have been approved by the FDA for use in the United States. The prescribing information says that 'No studies were conducted,' yet the medication uses a different adhesive to hold the micronized estrogen and has smaller dimensions than Vivelle Dot. As a retired pharmacist, I am angry that I am having to go through this situation again. It is frustrating that despite the ratio of surface area, mg's in the 'glue,' and dose being a 1:1 relationship, this medication was still allowed on the market with all of these differences. I have already made a formal complaint to the FDA, and I encourage others to do the same. Please call 1-800-FDA-1088 or report online at accessdata.fda.gov/scripts/medwatch/. The struggle is real, and action needs to be taken."

1 / 10
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113 Report
  • Not...
  • Taken for less than 1 month
  • February 8, 2023

For Postmenopausal Symptoms "I was given Dotti as I could not get my usual medication. Within a week, I was feeling depressed, was feeling hot all the time, and only getting 4 hours of sleep, and I have had issues with rage and have been isolating myself. This drug is horrible. Thank you, everyone, for having left reviews."

1 / 10
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46 Report
  • mar...
  • Taken for less than 1 month
  • June 6, 2021

For Postmenopausal Symptoms "My drug store replaced my Estradiol patch with Dotti. The first night, my restless sleep and dreaming. Daytime, I was cold and couldn't get warm. The second night, I experienced terrifying nightmares, woke up drenched in sweat two times. I was frightened, didn't know what was wrong with me. Figured it out! Another drug store was able to fill my regular prescription, and I was fine within a few hours. I question if this drug passed trials as a replacement for Estradiol."

1 / 10
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40 Report
  • Lov...
  • Taken for 1 to 6 months
  • February 17, 2023

For Postmenopausal Symptoms "Immediately after being switched from Sandoz to Dotti, my body went into the same horrible rigid muscle pains and terrible foot aches scenario that I had experienced prior to getting on any HRT. I dealt with it for 5 months and then asked to be put back on Sandoz. Within a week back on Sandoz, the horrible foot pain eased. After 3 weeks back on Sandoz, all the muscle pain and foot pain, as well as the sleepless nights that had returned, went away. I feel full of energy again too. I kept my Dotti package because I thought maybe it was a recall situation and I had gotten a bad batch for a number of months, but I haven't seen any recalls for it. All I know is that it absolutely doesn't work for me."

1 / 10
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18 Report
  • Hot...
  • September 2, 2020

For Postmenopausal Symptoms "Been having major hot flashes, lack of sleep for 2 years. Just was given Dotti 0.25 mg patch. On my 7th day and I notice a difference. Not flashing as often, and I have actually slept the past couple of nights. I go see my doctor tomorrow for a follow-up. My only concern is the risk of cancer. I will discuss this tomorrow. My mood has also improved! So far, very happy with this."

9 / 10
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28 Report

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  • cva...
  • Taken for 1 to 6 months
  • June 3, 2023

For Postmenopausal Symptoms "I'm horrified by what I'm reading, and now I think I know what's wrong with me. Menopause for 3 years. Dotti is what I'm using since insurance stopped paying for Estradiol. I've been having terrible symptoms and couldn't figure it out. Dry skin and hair, insomnia, night sweats, easily irritated, fatigue, and I've just had a period?!? Had all the old premenstrual symptoms such as breast tenderness, cramps, and a 4-day period, and MOODY. I do have an appt with my OB/GYN. If Dotti is the reason, I am not happy, as it seems NO ONE likes this patch!"

1 / 10
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13 Report
  • Gra...
  • Taken for 1 to 6 months
  • April 1, 2021

For Postmenopausal Symptoms "I am only one month in with Dottie, however, the difference for me has been nothing short of incredible! Within one hour of applying the patch, it was almost like the world seemed brighter. I was changing sheets in the middle of the night from night sweats, spending 40% of my life surviving hot flashes while others were surviving me, and was truly the prime example of a postmenopausal woman for the past seven years of my life. I was prescribed the Dotti patch and progesterone capsules to be taken nightly one month ago. I will say the first few days I fought a bit of nausea, have had trouble sleeping two nights, and have gotten a little emotional a time or two, but hot flashes have diminished to almost nonexistent. I have not had bad night sweats in three-plus weeks, and my moods are much more stable than before the hormone therapy. This is just my experience so far. Hope it helps! P.S. It is not pretty, I agree. I just try to conceal or put a pretty band-aid over it."

9 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.