Dotti and Mood Swings: What Users Say

• Iha...
• Taken for 1 to 6 months
• May 14, 2021

For Postmenopausal Symptoms "At the start of this year, my pharmacy began sending me Dotti patches instead of the ones I had been using. Gradually, my symptoms reappeared: unprovoked bouts of anger and irritability, mood instability, hair loss, and extreme skin dryness. Then came bouts of darker depression. I wondered if it was the change in patch manufacturer, but brushed it off. Then came the hot flashes and the night sweats; these progressed to full-on night drenching. Finally, I knew this wasn’t normal, began researching, and that led me to this review site. I am so grateful other women are reporting this because I was starting to think I was crazy! Thank you to the women who took the time to post experiences here. I just picked up patches from my old manufacturer, thankfully, and slapped one on. For years, the other manufacturer gave me relief. I’m so happy to be back on that. Dotti was completely ineffective for me."

• Kim...
• Taken for 1 to 2 years
• February 25, 2025

For Postmenopausal Symptoms "I'm 56, been postmenopausal since I was 46. I'd suffered such terrible hot flashes since I was 42. I just figured it was par for the course...but the hot flashes were so bad that I'd never had a full night's sleep since they started. Lack of sleep snowballs into a myriad of bad symptoms, brain fog, crappy memory, mood swings, zero libido...etc. I even lost my job because my memory was that bad! This went on and on until I seriously couldn't live like that anymore. So almost 2 years ago, I gave in and talked to my gyno, who immediately started me on the lowest dose Estradiol patch along with a progesterone gel cap. I felt relief after the first week! Hot flashes went away, and I felt like I had my life back. My dosages had to be tweaked along the way. Now the patches aren't strong enough, and I'm starting on a 2 mg estrogen pill. HRT is NOT the horrible drug they assumed back in the 70s. It's a lifesaver! And it's covered 100% by Wellpoint Insurance (NJ Medicaid), so there's no excuse!"

• KPa...
• Taken for less than 1 month
• July 22, 2021

For Postmenopausal Symptoms "I was so relieved to find these reviews. My doctor uses another pharmacy for 'ease' and, as a result, I got the Dotti Estradiol patch. I used it for four days. It does not work. I got hot flashes, red patches, mood swings -- the works. It felt like life was so bleak. Less than 10 hours back on Sandoz and things are looking up again. Red patches gone. No hot flashes... Why do they even make this patch?!"

• Lit...
• Taken for less than 1 month
• January 13, 2021

For Postmenopausal Symptoms "One week using Dotti, experienced marked increase in vasomotor symptoms, mood swings only relieved by switching to another manufacturer. Amneal representative stated to me it's not in their policy to replace. Let the buyer beware!"

• Mar...
• Taken for 1 to 6 months
• November 1, 2019

For Postmenopausal Symptoms "This Dotti patch doesn’t work! Provided no relief. Went from a stable estrogen level on another brand to 43 by the time I quit it. It doesn’t work. Went back to the other brand and instantly got relief from hot flashes and mood instability."

• LKa...
• November 12, 2020

"I am taking estradiol for Turner syndrome. The pharmacy OscoDrug switched from Mylan 0.025 generic estradiol patch to Dotti with terrible side effects including local redness and itching, as well as systemic ones: increased migraine frequency, depression, mood swings, fatigue, generalized malaise, and body aches. Mylan had some of these but to a lesser extent. The insurance will not cover Vivelle-Dot brand name, it seems that's the best on the market so far. We'll go through the appeal process. Generally, insurance and the pharmacy both want to push a cheap variation like Dotti. You need to fight for Vivelle-Dot like for everything that's right, don't give up, it's all worth it!"

• Dif...
• Taken for 6 months to 1 year
• December 10, 2024

For Postmenopausal Symptoms "I have gone through multiple Mylan generics as well as Lyllana, and none of them work for me. The only thing that keeps me from raging, horrible smells, horrible body aches, and loss of memory is Dotti. I don't have hot flashes, though I have night sweats periodically (Get the BedJet, never slept better!) My symptoms are more along the odder ones: itchy ears, a burning chemical smell that burns my nose, skin sensations like being itchy when nothing is there, hearing sounds that no one else does, weakness, severe fatigue, mood swings, rages, irritability, just overall malaise. If I change from Dotti, it all comes back. I had rashes under some of the other brands of patches, others didn't stick. I am a person who can't take any generic or store brand medications. I usually take 4-5 different generics before I find one that works and doesn't make me suicidal, so I know I'm not like most people. But I would lose my life if they take Dotti away, I can't survive without my Dotti estradiol."

• Gra...
• Taken for 1 to 6 months
• April 1, 2021

For Postmenopausal Symptoms "I am only one month in with Dottie, however, the difference for me has been nothing short of incredible! Within one hour of applying the patch, it was almost like the world seemed brighter. I was changing sheets in the middle of the night from night sweats, spending 40% of my life surviving hot flashes while others were surviving me, and was truly the prime example of a postmenopausal woman for the past seven years of my life. I was prescribed the Dotti patch and progesterone capsules to be taken nightly one month ago. I will say the first few days I fought a bit of nausea, have had trouble sleeping two nights, and have gotten a little emotional a time or two, but hot flashes have diminished to almost nonexistent. I have not had bad night sweats in three-plus weeks, and my moods are much more stable than before the hormone therapy. This is just my experience so far. Hope it helps! P.S. It is not pretty, I agree. I just try to conceal or put a pretty band-aid over it."