Dotti and Irritability: What Users Say

• Pit...
• Taken for less than 1 month
• April 11, 2023

For Postmenopausal Symptoms "This experience has been extremely unpleasant. All of my cardiac, vaginal, urinary, sleep, agitation, and hot flash symptoms have returned. I strongly believe that this medication should not have been approved by the FDA for use in the United States. The prescribing information says that 'No studies were conducted,' yet the medication uses a different adhesive to hold the micronized estrogen and has smaller dimensions than Vivelle Dot. As a retired pharmacist, I am angry that I am having to go through this situation again. It is frustrating that despite the ratio of surface area, mg's in the 'glue,' and dose being a 1:1 relationship, this medication was still allowed on the market with all of these differences. I have already made a formal complaint to the FDA, and I encourage others to do the same. Please call 1-800-FDA-1088 or report online at accessdata.fda.gov/scripts/medwatch/. The struggle is real, and action needs to be taken."

• Rho...
• Taken for 1 to 6 months
• August 25, 2021

For Postmenopausal Symptoms "I had been on another estradiol patch for about a year. My husband's employer requested we start using a mail prescription, and when we did, they switched me to Dotti patches. I started wondering why I was feeling crabby and irritable again, sort of like I did before taking the patches. Also, I’ve been gaining weight. Not sure if that is also from the patches. But I’ve requested switching back to my original patch. I still wasn’t sure if this was because of the Dotti patches, but after reading these reviews, I’m sure of it. Would not recommend."

• cva...
• Taken for 1 to 6 months
• June 3, 2023

For Postmenopausal Symptoms "I'm horrified by what I'm reading, and now I think I know what's wrong with me. Menopause for 3 years. Dotti is what I'm using since insurance stopped paying for Estradiol. I've been having terrible symptoms and couldn't figure it out. Dry skin and hair, insomnia, night sweats, easily irritated, fatigue, and I've just had a period?!? Had all the old premenstrual symptoms such as breast tenderness, cramps, and a 4-day period, and MOODY. I do have an appt with my OB/GYN. If Dotti is the reason, I am not happy, as it seems NO ONE likes this patch!"

• Anonymous
• Taken for 1 to 6 months
• May 7, 2023

For Postmenopausal Symptoms "This patch is horrible. I have scar marks from where the patch was placed on my inner thighs. My allergies are out of control. My irritability and hot flashes are back. I’m so angry that my pharmacy switched from Vivelle Dot to this patch when I found out I switched to another pharmacy, and they also sent me the Dotti patch. My insurance pays for name-brand medication, so this is completely unacceptable. I’ve asked the pharmacist in the past if this is the same medication, and they say they use the exact same quantities of the drug as the name-brand. I do not recommend this product."

• Not...
• Taken for 1 to 6 months
• July 10, 2022

For Postmenopausal Symptoms "Was on the Vivelle patch for many years and then Estradiol when it was available as a generic. Last fall, my med insurance changed and so did my mail-order prescription plan. Was automatically sent the Dotti patch. Started having symptoms I didn't relate to the patch until I made a connection and found this site - vivid, odd dreams, hot flashes, night sweats, and general irritability (hadn't had this for years on the other patches). Finally got my doctor to request the generic patch only. Of course, suddenly, it's not available through mail order, and I have to get it at a local pharmacy for more than twice the cost, and it's generic. But it's worth it."

• Dif...
• Taken for 6 months to 1 year
• December 10, 2024

For Postmenopausal Symptoms "I have gone through multiple Mylan generics as well as Lyllana, and none of them work for me. The only thing that keeps me from raging, horrible smells, horrible body aches, and loss of memory is Dotti. I don't have hot flashes, though I have night sweats periodically (Get the BedJet, never slept better!) My symptoms are more along the odder ones: itchy ears, a burning chemical smell that burns my nose, skin sensations like being itchy when nothing is there, hearing sounds that no one else does, weakness, severe fatigue, mood swings, rages, irritability, just overall malaise. If I change from Dotti, it all comes back. I had rashes under some of the other brands of patches, others didn't stick. I am a person who can't take any generic or store brand medications. I usually take 4-5 different generics before I find one that works and doesn't make me suicidal, so I know I'm not like most people. But I would lose my life if they take Dotti away, I can't survive without my Dotti estradiol."