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Estradiol User Reviews & Ratings (Page 3)

Brand names: Estrace, Estradiol Patch, Dotti, Estrogel, Climara, Vivelle-Dot, Lyllana, Evamist, Divigel, Femring, Minivelle, Depo-Estradiol, Estraderm, Alora, Delestrogen Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 5.8 out of 10 from a total of 587 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 37% reported a negative experience.

Reviews for Estradiol

Commonly mentioned side effects
  • Hap...
  • Taken for 2 to 5 years
  • May 20, 2015

Estradiol for Postmenopausal Symptoms "What a godsend! After menopause at 50, I first thought 'Yes, no more periods!' Then the fun started: night sweats, hot flashes at the worst times like during business meetings. My doctor started me on the patch .50, and within 2 days, it was like a miracle - I could sleep without a towel on my pillow, and the hot flashes disappeared. After a year, he dropped the dose to .375, and it's still working. If you are having to fight the sweats and flashes - talk to your doctor. This stuff works!"

10 / 10
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87 Report
  • Not...
  • Taken for 1 to 6 months
  • October 5, 2021

Estradiol for Postmenopausal Symptoms "Dotti 0.05 patch claims to be equivalent, but the stated amount of estrogen is less than the estradiol 0.05 patch. Six weeks after I was switched to Dotti by a pharmacy, I had horrible symptoms. Went back on the estradiol patch, and I am better. Safeway, Humana, and Costco are all using the Dotti patch. This patch should be pulled from the market."

1 / 10
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39 Report
  • Sta...
  • Taken for 1 to 2 years
  • September 23, 2020

Estradiol for Postmenopausal Symptoms "I started having hot flashes that were preventing me from sleeping, and my hair was falling out at my temples, and I had had a headache for 6 months. My skin actually hurt. I read the book *Estrogen Matters* to get ready to talk my doctor into giving me hormones. If your doctor believes the scam *Women's Health Initiative* study that says HRT is detrimental, you would probably find a different doctor. I started out at 0.5 and felt some relief. I moved quickly up to 0.75, more relief, and now I am at 1 mg, and I would say I have almost total relief. Hair is even partly coming back. I have a uterus, and so I am also taking progesterone, and periods are coming monthly-who cares? I sleep again, I have maybe a hot flash a week, and they are mild, and I plan to take this medication forever."

10 / 10
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47 Report
  • Tru...
  • September 14, 2016

Estradiol for Postmenopausal Symptoms "I am 50 years old. I had a Total Abdominal Hysterectomy in April and have been suffering wicked hot sweats. I would sweat so badly that my hair, legs, feet, hands, and face would get wet... so disgusting. It would take me a while to dry off. I started this patch on Monday and within 12 hours, I noticed a difference, and within 24 hours, the wet sweats were gone. I have to keep all the fans on in my house and have an industrial fan that I would stand in front of during my flashes. Yesterday (day 2), I did not have to turn on a single fan, and my wet sweats are completely gone. I only had a headache the first night, and now I feel fantastic and normal. I still have the occasional hot flash, but it is short, and I don't break out in a sweat."

10 / 10
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76 Report
  • Hap...
  • June 12, 2019

Estradiol for Postmenopausal Symptoms "Mylan Estradiol Patch 1.0 seems to be ineffective! Suffering from menopausal symptoms due to a complete hysterectomy. Booted off the good stuff... Minivelle. Due to change of insurance, even though I have full coverage! Insurance won’t pay the $450 cost for a 3-month supply. I wonder what’s even on the Mylan Estradiol Patch, is it even real?"

1 / 10
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55 Report

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  • Ano...
  • Taken for 2 to 5 years
  • October 27, 2021

Estradiol for Postmenopausal Symptoms "Femring 0.1 is the only thing that has really worked for all my symptoms, especially moodiness, depression. After trying everything else, I was so pleased to find it. However, it definitely doesn't last for 90 days. I've noticed the past year it has lasted 8 or 9 weeks at most. This round it lasted 6 weeks, and I immediately know when it's not working. I literally feel terrible overnight - hot flashes, irritable, depressed, food cravings. I'm desperate to somehow stockpile it! I wish the company making it could address this. But like so many women's health issues, it's not that important to anyone but us."

10 / 10
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37 Report
  • mar...
  • Taken for less than 1 month
  • June 6, 2021

Estradiol for Postmenopausal Symptoms "My drug store replaced my Estradiol patch with Dotti. The first night, my restless sleep and dreaming. Daytime, I was cold and couldn't get warm. The second night, I experienced terrifying nightmares, woke up drenched in sweat two times. I was frightened, didn't know what was wrong with me. Figured it out! Another drug store was able to fill my regular prescription, and I was fine within a few hours. I question if this drug passed trials as a replacement for Estradiol."

1 / 10
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40 Report
  • Rut...
  • Taken for less than 1 month
  • June 5, 2020

Estradiol for Postmenopausal Symptoms "I used to use Climara. Great option. After I changed insurance, I had to use a Mexican brand that worked really well. After I moved to another state, I had to get a US brand. I was given Mylan Estradiol patches, and after 2 days or less, they fall off. I just feel I wasted my money, and they are not cheap."

1 / 10
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47 Report
  • Hot...
  • Taken for 2 to 5 years
  • November 8, 2015

Estradiol for Postmenopausal Symptoms "Worked wonderfully for my mood swings, hot flashes, night sweats, and sleepless nights. Used it for 4 years. Now I have been off for 2 months and can't stand the reappearance of all those nasty menopausal symptoms. I may have to go back on it."

10 / 10
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75 Report
  • SEA...
  • Taken for less than 1 month
  • June 19, 2023

Estradiol for Oophorectomy "I'm an RN who has worked in OB/GYN and has used bio-identical hormones and has been wearing patches since having an oophorectomy in 2006. Twice I have tried generic estradiol patches after running out of Vivielle Dot, and just recently ran out due to the pharmacy not sending my Climara 0.1 mg on time. Both have worked very well for me, but they don't sit well if I've bathed or worked out. Tegaderm may be the best answer. Here is my big concern. Each time I have tried the generic (recently) MYLAN brand, which is generic, I've had an instant return of low estrogen migraine with the added side effects of extreme agitation. So it is worse than nothing. Why!!?? If a drug company can't make something that helps them, why make it at all? Furthermore, shouldn't they consider the adage in the medical field 'first do no harm'?? Why is this okay? Shame on MYLAN company. Disgusting. I'm very disappointed. Oh, and to add insult, I wasted $155 dollars-the cost of the med. Beware. Please use brand-name products."

1 / 10
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23 Report
  • smi...
  • Taken for 10 years or more
  • November 3, 2017

Estradiol for Postmenopausal Symptoms "I have used the patch for nearly 30 years after total hysterectomy (first patch discontinued and switched to Vivelle-Dot approx 10 yrs ago). I have tried going off and feel it's not worth the agony. Have looked for generic but have found none that really are the same although I see in the posts Sandoz recommended by someone, so may try again. Vivelle (at least when on Medicare) is very expensive with little or no coverage and if any copayment must jump through hoops---very discouraging. This is the only medication I use and at 72 feel great other than payments for this, but justify good health comes at a price!"

9 / 10
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59 Report
  • lro...
  • Taken for less than 1 month
  • February 4, 2024

Estradiol for Postmenopausal Symptoms "I am in perimenopause and started having horrible hot flashes 4 months ago. 10 a day at least. Crazy fluctuations between hot flashes and cold chills and shivering. Night sweats at night. Was miserable. Finally found a GYN who is current with the research and she prescribed the patch and progesterone pills. She initially prescribed a brand name 2x a week 0.05 patch. Well the manufacturers are all discontinuing making the brand name patch because the patent is up and insurance will only pay for generic. Furthermore, there is a patch shortage nationwide, so there was only one generic available - Mylan. I Googled and read not so pleasant things and was super freaked out but had no other options, so I tried it. After one week, I noticed I had fewer hot flashes. After 2 weeks, I had ZERO hot flashes. OMG, what a relief. It’s wonderful not to have crazy temperature changes all day and night. Yes, it irritates my skin, but the patch has a lot fewer risks than pills, so it's okay."

9 / 10
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16 Report
  • Mel...
  • Taken for 1 to 6 months
  • October 26, 2019

Estradiol for Atrophic Vaginitis "This is much better than the generic. It is costing me nearly $430 a month, but it is worth it. I have a high-stress job, so my body eats it up. I have been using the generic for years, and I felt it should be working better, it just wasn't doing it for me. I decided to try the real one. It took a month and a half for my body to adjust, but once it did, I felt ten years younger. I can now work five days a week, which helps to pay for the medication. I no longer require a nap, the bottom of my feet does not have dry skin anymore, my face looks younger, it filled out. I don't have that gaunt look as much. The atrophy in my vagina is gone. I feel like exercising and doing things outside of the house. It is worth the money, but it is a shame that it costs so much."

10 / 10
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46 Report
  • Ges...
  • Taken for less than 1 month
  • December 17, 2020

Estradiol for Postmenopausal Symptoms "Has anyone experienced that the Estraderm patch does not stick to the skin? It's driving me crazy. Even though I clean the skin with medical swab wipes, wait for the area to dry, and it still doesn't stick."

2 / 10
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38 Report
  • tan...
  • May 6, 2015

For Postmenopausal Symptoms "Brilliant, was having low mood, terrible hot flashes where I didn't want to venture out the door!! By fights with hubby! Mood has improved. Hope to keep on this long term. I had a hysterectomy at 41, refused to take it because of the cancer risk at first, but my symptoms were awful so I decided the benefits outweigh the risks."

10 / 10
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70 Report
  • Jun...
  • Taken for 1 to 6 months
  • April 23, 2020

Estradiol for Postmenopausal Symptoms "I had the Sandoz patch, and it was great - a nice, thin patch that I forget is there except that I feel much better. The next month, I got the Mylan patch that is covered by my provider. It is thicker and catches just a little bit on the edges. More importantly, it leaves red marks underneath upon removing it and small marks that look like burns around the edge. I've also seemed to have some itching around the patch while it is on. I will be switching back to Sandoz."

8 / 10
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42 Report
  • Suz...
  • Taken for 1 to 6 months
  • March 1, 2023

Estradiol for Postmenopausal Symptoms "My pharmacy changed to Dotti brand manufacturer at the end of November 2022. I loved how the estrogen patch was smaller and less visible. However, my postmenopausal symptoms started back within three weeks of beginning the Dotti patch. I had increasing hot flashes, dry skin, brain fog, and fatigue. I scheduled an appointment with my OB/GYN in February to have my hormone levels rechecked. She discovered I had almost NO estrogen in my system. NONE. She said my body was not absorbing the medication. However, I have not had problems absorbing any other brand over the last 4 1/2 years. The Dotti brand estrogen patch was useless for me. I had to switch pharmacies to use a different manufacturer."

1 / 10
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22 Report
  • Rho...
  • Taken for 1 to 6 months
  • August 25, 2021

Estradiol for Postmenopausal Symptoms "I had been on another estradiol patch for about a year. My husband's employer requested we start using a mail prescription, and when we did, they switched me to Dotti patches. I started wondering why I was feeling crabby and irritable again, sort of like I did before taking the patches. Also, I’ve been gaining weight. Not sure if that is also from the patches. But I’ve requested switching back to my original patch. I still wasn’t sure if this was because of the Dotti patches, but after reading these reviews, I’m sure of it. Would not recommend."

1 / 10
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32 Report
  • Dis...
  • October 26, 2016

For Postmenopausal Symptoms "I started with perimenopause symptoms at 45 years old, beginning with heart palpitations and mild hot flashes. Shortly thereafter, all hell broke loose. Night sweats, hot flashes, crying, major insomnia, and an 18-pound weight gain in less than one year. I had no quality of life, so I went on the estradiol patch. I now feel human. Sleeping great and no night sweats. An occasional hot flash, but I can live with that. I went off for about a year, and almost everything came back with a vengeance. I'm back on!"

10 / 10
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62 Report
  • Lil...
  • Taken for 1 to 6 months
  • February 20, 2021

Estradiol for Postmenopausal Symptoms "My biggest concern is that I am not getting the relief of post-menopause even though I am using a 0.1 mg patch because the patch does not stay on my skin. I have been using the estradiol patch for many years. I was using Vivelle Dot until it was not covered by my insurance and switched to Mylan Labs. It would be nice if these patches could stay on my skin to rate the effectiveness of the medication."

2 / 10
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35 Report
  • Lil...
  • July 4, 2016

For Postmenopausal Symptoms "I tried to wean off my other not-so-effective hormone pills but suffered terrible backlash. So, I went to see a different and more experienced OBGYN doctor and began applying Estradiol 0.05 coupled with Progesterone 100MG treatment. It takes about 10 days to see the full positive results. I am almost one month into this treatment now, and it has stopped hot flushes, I sleep through the night, stopped horrible stress attacks, stopped near-fainting temperature surges, my facial skin looks tighter and younger, and strangely, it makes me think about the birds and the bees. Knock on wood, I hope this medicine works for me for a long time to come. I am 64 years old, 5'3'', weight 126 lbs. Use an alcohol wipe and dry skin before applying the patch, it sticks better."

10 / 10
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61 Report
  • Anonymous
  • Taken for less than 1 month
  • September 2, 2020

Estradiol for Postmenopausal Symptoms "Estraderm MX 25. These patches are terrible. They don’t adhere to the skin! After one day, it comes off. I normally take Estradot 25, but it is sold out across the state and unavailable! Not impressed... and I’ve been getting hot flushes again..."

2 / 10
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38 Report
  • Cin...
  • Taken for 1 to 2 years
  • August 19, 2020

Estradiol for Postmenopausal Symptoms "Sandoz Estradiol Patch does not stick. It does not peel, instead, the entire patch comes loose at once. I get 2 days, maybe 3 days out of a patch. Do not accept Sandoz brand from your pharmacy, you will be wasting your money."

1 / 10
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44 Report
  • Ann...
  • June 2, 2020

Estradiol for Oophorectomy "I had a hysterectomy/bilateral oophorectomy in February 2019. Immediately after surgery, I had hot flashes and high blood pressure. I was put on Climara, and everything was better. My employer changed insurance providers 1/2020, and they no longer covered Climara. They substituted Sandoz. I started Sandoz in March 2020 after Climara ran out. I noticed right away that the Sandoz patches do not stick. After being on them a few weeks, I’ve had a 20 lb weight gain, pitting edema in my legs, hot flashes, and headaches. I went to my doctor, and all blood work was normal. Thyroid function is okay. The problem is the Sandoz patches. They are faulty. They curl even under hydrocolloid dressings. The inconsistent hormone level is wrecking havoc on my body. I filed a complaint with Sandoz. I now have to pay $150 for Climara instead of the $25 for Sandoz. If Sandoz isn’t working for you, file a grievance with the company. They are putting out an inferior product. I’m also filing a complaint with the FDA."

1 / 10
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41 Report
  • Suz...
  • August 19, 2013

Estradiol for Postmenopausal Symptoms "Have been on it for 2 months, was getting hot flashed all day long. Night sweats even worse. Within days after starting the medicine, they pretty much stopped! No more on and off with my fan - sleeping through the night! And now, I ran out and haven't had it in 5 days (need to call for a refill prescription) and it's all BACK. Covers off and on all night long. This REALLY works for hot flashes!"

10 / 10
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74 Report

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