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Estradiol User Reviews & Ratings (Page 5)

Brand names: Estrace, Estradiol Patch, Dotti, Estrogel, Climara, Vivelle-Dot, Lyllana, Evamist, Divigel, Femring, Minivelle, Depo-Estradiol, Estraderm, Alora, Delestrogen Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 5.8 out of 10 from a total of 587 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 37% reported a negative experience.

Reviews for Estradiol

Commonly mentioned side effects
  • Ano...
  • Taken for 10 years or more
  • April 30, 2021

Estradiol for Postmenopausal Symptoms "Had a complete hysterectomy at 40 years old and have been on the patch for 23 years. It has been a lifesaver. Docs have tried to wean me off of it, and menopause symptoms came back within 2 days: sweating, mood swings/irritability, can't sleep, overall misery. Being on the patch, I feel close to normal and have good skin for 63 years old. I went off the patch for a week and had to get back on, as quality of life was horrible without it. I felt best on .5 and was on it for 20 years, but Doc reduced the dosage to .375 and wants me to be off them permanently because they claim it's risky for cardiovascular health (even though it's supposed to be good for bone health)."

9 / 10
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26 Report
  • qui...
  • Taken for 2 to 5 years
  • November 29, 2014

For Gender Dysphoria "After spending over two decades without any treatment, I sought help for my transsexualism; my doctor first prescribed spironolactone, followed by estradiol. It took a bit of time to find the proper dose to balance my estrogen levels, but patience paid off-no negatives! With estradiol, I've finally been able to start building a life for myself!"

10 / 10
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57 Report
  • del...
  • February 13, 2021

Estradiol for Postmenopausal Symptoms "I have used the Climara patch since 2003, with no problem sticking, but now, since later 2020, I have a terrible problem with wrinkling and coming off. I know why, they have cut down on the thickness of the plastic, so therefore are putting less glue or whatever they put to stick on the patch. They're saving money but causing us problems. Now I have to put a large band over the patch to make sure it will stay on. I have called the company and reported it to my drug store, CVS. Now I have to wait to see what they will do."

8 / 10
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27 Report
  • lkl...
  • September 5, 2008

Estradiol for Postmenopausal Symptoms "I started using the Vivelle-Dot patch after having a total hysterectomy. Before starting the patch, I was having vaginal burning & itching, hot flashes, and night sweats. Within a week of starting the patch, all of these symptoms were resolved. To date, I've not experienced any side effects."

10 / 10
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75 Report
  • Ros...
  • Taken for 1 to 6 months
  • January 7, 2016

Estradiol for Oophorectomy "After using Vivelle patch for a number of years following a complete hysterectomy, my insurance company refused to pay for it at the same level due to the Mylan generic. Within a few weeks of switching to the generic, I began to develop adverse symptoms (insomnia, breathing difficulties, anxiety, constant headache). When I made the connection and switched back to Vivelle, the symptoms subsided. Unfortunately, my insurance company refuses to pay for the brand name at the same level, but this is not the same drug. Now instead of paying $40 for a 3-month supply, my cost is over $150 to obtain the brand name product."

1 / 10
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50 Report

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  • god...
  • Taken for 10 years or more
  • January 19, 2013

Estradiol for Oophorectomy "I had ovarian cancer and had an oophorectomy. My oncologist wanted me to use this drug for at least 10 years. Started with a higher dose and have gone down to 0.05. I have tried dropping it to 0.025, but noticed I was having hot flashes and lack of sleep at night. I have gone back to the 0.05 and enjoy it so much more, although I am now going on my 12th year of taking it. Trying to wean off of it, but without the ovaries, it is hard. Love this patch!!"

10 / 10
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62 Report
  • KDS...
  • October 8, 2020

Estradiol for Oophorectomy "After my hysterectomy, I was having post-menopausal symptoms. My gynecologist mentioned options, and I chose the transdermal patch. Initially, I used Climara because the generics were not on the market. Climara was great. Eventually, I was switched to the Sandoz-manufactured patch, which also worked great. This year, my prescription was filled with the Mylan-manufactured patch, and those patches just fall off. It is ridiculous-a HUGE waste of money, plus all of the symptoms returned. So, I asked my pharmacy if they could get the Sandoz brand, but it was on backorder until I believe this month (Nov. 2020). They recommended I check with other pharmacy chains, so I did. I eventually found a pharmacy with Sandoz patches in stock. Each pharmacy that did not have the Sandoz brand told me it was on backorder. So, I was lucky to find a pharmacy that had the Sandoz brand available. As soon as I started wearing their patch again, my symptoms vanished. I do intend to report the Mylan brand to the FDA."

10 / 10
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30 Report
  • txt...
  • October 14, 2012

Estradiol for Postmenopausal Symptoms "I had a total hysterectomy and experienced terrible hot flashes. I began with a dosage of 0.05, but the hot flashes continued, although less severe. My doctor changed the dosage to 0.1, and the hot flashes are a thing of the past. I've only been on this medication for 3 months, but haven't experienced any side effects so far."

9 / 10
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63 Report
  • Anonymous
  • November 8, 2017

Estradiol for Oophorectomy "At the age of 43, I had a complete hysterectomy due to out-of-control endometriosis. One week after surgery, my doctor prescribed Climara, and almost 21 years later, I'm still using it. I never have hot flashes or any other symptoms of menopause. The patches have occasionally come off, but that's my own fault if I don't make sure to get it firmly attached. If you rub it on there really well, it'll stay put all week. I don't ever plan to stop using them. I also skip using my insurance and order them from a Canadian pharmacy and pay out of pocket. Cost with insurance in the US=$400 per month. Cost from Canada=$40 per month. It's the exact same thing, manufactured by Bayer."

10 / 10
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39 Report
  • Pam...
  • Taken for 2 to 5 years
  • July 31, 2024

Estradiol for Postmenopausal Symptoms "I feel there is an assault on women. These patches are expensive and the ones that are thin, see-through so it doesn't show through your clothing are either not readily available. Something women must have should be affordable, reliable, stay in place without being thick, cumbersome, and irritating. How dare pharma keep screwing us over. We need to demand better. Mylan is garbage, but all are pricey."

9 / 10
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7 Report
  • Sup...
  • Taken for 1 to 2 years
  • April 5, 2018

Estradiol for Postmenopausal Symptoms "I have more energy and have noticed that I care about my physical appearance. I am sleeping better and can find words again on the brand name Vivelle-Dot. The pharmacy tried to give me the generic, but that doesn’t seem as effective. It’s way too expensive, but I am paying the price for a better quality of life."

8 / 10
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37 Report
  • Kor...
  • March 26, 2017

For Postmenopausal Symptoms "At 46, I had a total abdominal hysterectomy 6 months ago due to adenomyosis and severe endometriosis. Had no hormone therapy at first, the doctor took a wait-and-see approach. One month ago, I started having intense hot flashes and joint inflammation. Doctor prescribed 1 mg estradiol a week ago, and I noticed my symptoms vanished almost completely by day 2. I learned after trial and error that taking it in the morning works best for me as it gives me a ton of energy. I'm starting to feel human again."

10 / 10
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43 Report
  • Anonymous
  • Taken for less than 1 month
  • September 27, 2016

For Postmenopausal Symptoms "I have been using estradiol for a week now, and I only wish I would have gone and seen my doctor sooner. After one day, I could tell a difference with my moods. I don't feel so wired or on edge anymore. I did not notice my mood swings, but I'm sure my family did...lol My hot flashes are gone. Thank you!"

10 / 10
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44 Report
  • Anonymous
  • December 24, 2010

Estradiol for Postmenopausal Symptoms "I have used a 0.75 patch for 6 years. To make it stick better, rub your skin with alcohol and let it dry. Press on for about 20-30 seconds. Really, the only thing I find frustrating is the fact that by the 5th day my body is clearly not getting as much medicine, and I start having body symptoms to parallel this. I also have very sore knots in my breasts, especially the first few days. But other than this, it has been a life-saver since I have post-surgical menopause."

8 / 10
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64 Report
  • Lis...
  • Taken for less than 1 month
  • November 13, 2018

Estradiol for Postmenopausal Symptoms "Taking 0.25 mg 1/x daily. Thought I could get through radical hysterectomy without HRT and suffered 8 months with minor symptoms as hot flashes, but most significant was major depression. Mental chemistry balances out within 30/60 minutes of Divigel application. To date, not noticing any side effects."

9 / 10
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33 Report
  • KPa...
  • Taken for less than 1 month
  • July 22, 2021

Estradiol for Postmenopausal Symptoms "I was so relieved to find these reviews. My doctor uses another pharmacy for 'ease' and, as a result, I got the Dotti Estradiol patch. I used it for four days. It does not work. I got hot flashes, red patches, mood swings -- the works. It felt like life was so bleak. Less than 10 hours back on Sandoz and things are looking up again. Red patches gone. No hot flashes... Why do they even make this patch?!"

1 / 10
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22 Report
  • Hot...
  • September 2, 2020

Estradiol for Postmenopausal Symptoms "Been having major hot flashes, lack of sleep for 2 years. Just was given Dotti 0.25 mg patch. On my 7th day and I notice a difference. Not flashing as often, and I have actually slept the past couple of nights. I go see my doctor tomorrow for a follow-up. My only concern is the risk of cancer. I will discuss this tomorrow. My mood has also improved! So far, very happy with this."

9 / 10
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28 Report
  • jes...
  • Taken for 1 to 6 months
  • November 5, 2018

For Gender Dysphoria "Estrogen. It's the best estrogen. Makes growth of breast tissue. But seriously, I can't recommend estradiol enough. I've been taking it sublingually for around 4 months now (2 mg daily for the first 3 months, increased to 4 mg last month), and I feel like an entirely different person. My skin feels so much softer (even though it's still just as dry >:( ), and I've noticed a fair bit of breast growth (they look a bit bigger but feel much different due to an increased amount of tissue), as well as more fat on my face. The one downside is the mood effects; my emotional lows are pretty low. Luckily, my highs are much higher than they ever were before. I'd recommend any trans woman get on estradiol ASAP (provided they're not on it already, haha)."

10 / 10
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35 Report
  • apr...
  • Taken for 2 to 5 years
  • April 18, 2015

For Postmenopausal Symptoms "Been using estradiol patches for the past 2 years since my full hysterectomy. I am 39 years old. No side effects. Can't live without them. One day with no patch and hot flashes, fatigue, and moodiness is back."

10 / 10
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46 Report
  • Lit...
  • Taken for less than 1 month
  • January 13, 2021

Estradiol for Postmenopausal Symptoms "One week using Dotti, experienced marked increase in vasomotor symptoms, mood swings only relieved by switching to another manufacturer. Amneal representative stated to me it's not in their policy to replace. Let the buyer beware!"

1 / 10
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24 Report
  • Wel...
  • Taken for less than 1 month
  • June 28, 2012

Estradiol for Primary Ovarian Failure "I am in my early forties and menopause hit me at an early age. I struggled with whether or not I should go on HRT due to the risks. With that said, the symptoms were creating sheer havoc in my life (severe hot flashes, night sweats, insomnia, and decreased libido - my poor husband). I am happy to say that after my first application, I slept through the night for the first time in two years! My hot flashes have decreased and I don't have that foggy feeling in my head. I am on Vivelle Dot and a progesterone regimen (light doses). I began Vivelle Dot two weeks ago and would highly recommend it."

10 / 10
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57 Report
  • spu...
  • September 11, 2015

For Postmenopausal Symptoms "In short, upon having my name-brand hormone patch replaced by this awful generic, I basically had my estrogen level drop to almost nothing in less than four months. The patch didn't stick, it kept coming off. I started experiencing all post-menopausal symptoms to the extreme. I didn't know what was going on at first. This generic will not do the job. I can't believe the FDA approved this generic medication! It has been the worst 6 months of my life! Since going back on the name brand, after just one month, my estrogen level is increasing and all menopausal symptoms are starting to go away. To anyone considering the money saving is cashing in their own sanity, it's not worth it! I'd give it 0, but that's not an option."

1 / 10
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48 Report
  • Gra...
  • Taken for less than 1 month
  • August 22, 2023

Estradiol for Postmenopausal Symptoms "Had mild menopausal symptoms and confirmed menopause. Since I was under 40, the doctors insisted on HRT and this patch. I was reluctant due to the risks, but I followed doctors' orders. This patch opened a new door in life for me. My sex drive is back and stronger than ever. A gentle gust of wind induced arousal, and I have never felt more pleasure. This is all because of the increased estrogen. All other symptoms stopped. I am not sure if insomnia stopped because I now wake up every 3 hours to touch myself or hope my husband is awake or able to 'sleepwalk' to relieve me. Wow. Hope this stays like this forever. Highly recommend."

9 / 10
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14 Report
  • Fru...
  • Taken for less than 1 month
  • August 16, 2023

Estradiol for Postmenopausal Symptoms "I just started the Mylan estrogen patch three days ago due to not getting any absorption from the pill. Like many other women commenting, half of this oversized patch comes unstuck while I'm taking a bath, so I have to use the blow dryer after bathing to get it to attach again, which leaves me wondering if that will make it less effective. The struggles of menopause are real, and I'm hoping this medicine will help if I can get it to stay on! To all the women having a hard time with menopause, I truly empathize!"

8 / 10
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12 Report
  • Pat...
  • Taken for less than 1 month
  • August 24, 2021

Estradiol for Postmenopausal Symptoms "I had a terrible vasomotor reaction. First and last time I used it, after 18 hours, the patch bottomed out, and I started having hot flashes. I was shaking, had a brain-buster headache, and severe nausea. Fortunately, I still had some of my generic Noven patches left over. I ripped off the Dotti and put on the one I usually used, and within 30 minutes, I was fine. Dotti is garbage, yet pharmacies are pushing it right now. Must be getting paid to do so."

1 / 10
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21 Report

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