Skip to Content

User Reviews for Imvexxy

Imvexxy has an average rating of 5.0 out of 10 from a total of 46 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 47% reported a negative effect.

Condition Avg. Rating Reviews Compare
Atrophic Vaginitis  
5.2
32 reviews 54 medications
Dyspareunia  
4.6
14 reviews 3 medications
Summary of Imvexxy reviews 5.0 46 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Imvexxy

calinative · Taken for 6 months to 1 year November 17, 2020

For Dyspareunia: “I have been using Imvexxy for 6 months. I use the 10mcg one time per week. I would be fine using the 4 mcg twice per week, but it is easier to use the 10 mcg once per week. One minor side effect I noticed is that sometimes I get a slight pelvic cramping a couple of hours after I insert it. It usually does not last more than a few minutes. Other than that, so far it is working for me. I am finally able to resume intercourse with no issues. Everything feels like it was before menopause. I spent a lot of money on the Mona Lisa touch prior to using Imvexxy and it did not work at all.”

9 / 10
Was this helpful?YesNo
whims · Taken for 2 to 5 years January 6, 2021

For Atrophic Vaginitis: “I'm 65 years old I started Imvexxy when I turned 62 and it worked for me I thought life was great again then I turned 65 and Medicare/Blue Cross entered my life the price is over 200 dollars a month for me and of coarse my insurances will not cover that at all so it is out of my pocket ! I had to turn to a different brand this brand does not work for me sad to say . Why would Imvexxy get you hooked and then once you really need at our age and you cant afford it !!!!!”

8 / 10
Was this helpful?YesNo
Lea · Taken for 6 months to 1 year November 13, 2020

For Atrophic Vaginitis: “I have been taking Imvexxy 10mg twice a week for about 10 months now. I had dryness on the outside of my personal area, more so then the inside dryness. I'm 64 with a healthy sex life. My husband thought it made me too lubricated and he didn't care for it. After two months I noticed night sweats, and some hair loss along with slight headaches. Mostly the night sweats was my big problem. I adjusted to 1 time a week of the 10mcg for a month, but still had night sweats. Now, I have been totally off Imvexxy for two weeks and noticed the night sweats have lightened up a bit. I am going to continue to stay off for 6 weeks to see if there is a big difference with the night sweats, hoping they disappear completely. I did not have this problem before I was on Imvexxy. The reason I was checking out these reviews was to see if anyone else had these same side effects, please let me know if you do.”

8 / 10
Was this helpful?YesNo
Kimmiepoo11 September 16, 2020

For Atrophic Vaginitis: “After dealing with atrophy following a total hysterectomy, my Doc suggested Imvexxy. Let's start with the positives: It DID what it was supposed to do, painful sex vanished after using it only a week and 1/2 and I felt better in the nether regions. Now for the "not so" positives: I noticed my hair thinning, and had a slight headache. In the 2nd week I noticed a rash on my arms(elbow down) and legs. My Family Doc treated me with steroids, but it started right back following treatment, I decided to stop Imvexxy on a hunch, and after nearly two weeks the rash began to fade. When I mentioned this to my Gyn, she said you must be allergic to coconut oil.... I use coconut oil every day with no issues. The ONLY thing different before all this mess was starting Imvexxy. Bottom line if anyone did have a rash after this medication and was told "That's not the cause." by their Doc. you are not alone. I am trying another (non-hormonal) product as it had some good reviews...just to see.”

4 / 10
Was this helpful?YesNo
kasey · Taken for 1 to 6 months November 16, 2019

For Dyspareunia: “Pros: packaging is better than Yuvafem and Vagifen since it is inserted manually without all those plastic applicators. Cons: The first time I went to renew the Rx they hiked the monthly price by $15 (from $35 to $50). Otherwise I would have continued trying it for longer. Instead I ended up using it for only 8 weeks. The tablet dissolves easily, but that makes for significant discharge overnight. The tablet is pink (they use Red#40) and the discharge stains clothes (needed to use a stainremover) so I needed to use pantiliners at night.”

4 / 10
Was this helpful?YesNo
Relief at last · Taken for less than 1 month November 4, 2019

For Atrophic Vaginitis: “I can't believe how quickly this worked for me. I am using the 10mcg, and I noticed a big difference after one use. I never realized how bad my situation was until I realized I was moist and comfortable down there the morning after the first dose. (Sorry if that is TMI!) I was having terrible burning, itching, painful intercourse, and a feeling that I always had to urinate. I'm 47 and still menstruating, but my gynecologist recommended this drug. I haven't been using it for very long, but so far so good. I read the full insert and read two books (Estrogen Matters and The Estrogen Window) before deciding to take the plunge. I am still worried about the possibility of hair loss. Some users mentioned that side effect. For the record, I also have RA and secondary Sjogren's Syndrome. I take a lot of immunosuppressant drugs. I hate to add to the medication list, but I was absolutely miserable and getting frequent UTIs from the dryness.”

8 / 10
Was this helpful?YesNo
Lolo · Taken for 1 to 6 months April 18, 2021

For Atrophic Vaginitis: “I began Imvexxy hoping it would help with the dryness and itchiness I sometimes feel. I have not been sexually active in years, but the dryness drives me crazy. This has not helped with the dryness, though the itchiness has stopped. Then, I suddenly began to get boils, and more than one. I’ve never had them before. I began to feel rundown and fatigued as well. My eyes began to feel dry as well. I won’t continue using this product. I’ll definitely try something else.”

2 / 10
Was this helpful?YesNo

Frequently asked questions

SassyG · Taken for 1 to 6 months February 13, 2020

For Dyspareunia: “I have been taking Imvexxy 10mg twice a week for 6 months now at night before bedtime. It has not helped at all with painful intercourse and dryness. My dr told me not to expect instant results and to try it for a few months. I had also hoped for at least a small bump in libido, but nothing. I usually get a slight headache the day after using and there is some external burning as well. My hair feels thinner. I don't like having to insert the capsule manually; it's awkward and never feel that I've inserted it far enough. Have not had any of it come out, though. Also feel that I may be starting a yeast infection. This is not for me and I will discontinue after this month.”

1 / 10
Was this helpful?YesNo
Tamara October 12, 2020

For Atrophic Vaginitis: “I’m 51 and been in menopause for a few years. Imvexxy and progesterone 100mg have helped me 100 percent! I have been taking both for 2 weeks and intercourse is comfortable and pleasurable. I had a few headaches the first week. No other side effects. My husband and I couldn’t be happier with the results of Imvexxy. He thinks my breasts feel larger than before too. Thankful customer.”

10 / 10
Was this helpful?YesNo
ABK · Taken for less than 1 month December 24, 2020

For Atrophic Vaginitis: “My Dr. wanted me to take this every night for two weeks. I had to discontinue use after 4 nights. When I would get up in the morning, there was so much discharge. I had a horrible headache the entire four days that I took it. It made my rosacea flair up. I felt tired and run down and my body felt sore.”

3 / 10
Was this helpful?YesNo
Lorelei · Taken for 1 to 6 months February 12, 2019

For Atrophic Vaginitis: “Imvexxy 4 mcg is amazing vaginal suppository! I was extremely dry and now I have moisture again ,and feel terrific! I highly recommend this product ,it has changed my life!!!!! The best thing is, no side effects!!!!”

10 / 10
Was this helpful?YesNo
Ingrid · Taken for 6 months to 1 year August 3, 2020

For Dyspareunia: “Have used Imvexxy for over a year. Dye should NOT be in a vaginal insert. I also have had leakage - with used overnight or during the day. A year on the medication - sex is still extremely painful and atrophy has not improved per my yearly exam. Many issues with getting the pharmacy to properly bill. Now my prescription just went up by more than $11 per month. Called the Imvexxy number and they tell me I have to wait until Jan 2021 to get another discount card. This has been an extremely frustrating experience between fighting to have the discount applied each month, no improvement with the painful sex, and the leakage of the drug.”

2 / 10
Was this helpful?YesNo
Dee · Taken for 6 months to 1 year October 1, 2019

For Dyspareunia: “I took Imvexxy for four months. It is an easy pill to pop in with little mess. However, I think the pill should be white because the pink discharge that you get from the pill could be confused with spotting. Anyway, the medicine worked right away for my pain with sex. However, I could not tolerate the pelvic cramping, breast tenderness, and hair shedding. I had to go off of it because I was too uncomfortable with these side-effects. I am now on Estrace cream and so far no bad side effects, but the only downfall is that it is messy. Ugh. Nothing is ever a perfect fit :)”

5 / 10
Was this helpful?YesNo
col June 30, 2020

For Dyspareunia: “Used one Imvexxy tablet. Felt burning. Spotting, which I thought was blood. It was washed out pinkish, but it may have been the pink outside of the tablet. Felt burning for a day or two and will not use again.”

1 / 10
Was this helpful?YesNo
Jean · Taken for 1 to 6 months January 21, 2019

For Dyspareunia: “I had been taking Imvexxy for almost 5 months. I had seen no positive changes. I started having heart palpitations after 3 months of usage. Then I began to notice pain from my fibroid tumors returning. I have discontinued taking this product. I’d rather have painful intercourse then live with fibroid tumors and heart palpitations. I’m wondering how many other women have had these same problems and never reported them.”

1 / 10
Was this helpful?YesNo
SweetP · Taken for 1 to 6 months November 5, 2020

For Atrophic Vaginitis: “I just started my 3rd month of using the 10 mcg insert of Imvexxy. The dryness has been completely reversed, which in turn stopped my chronic BV. Yay!! However, I've been feeling nauseous and crampy with a mild headache for the past 6 weeks. I also seem to be experiencing more hot flashes and night sweats. I don't want to believe its the Imvexxy causing this and the low back pain but, since nothing else has changed, and I take no other medications, I can only assume it is the Imvexxy. I am almost 60 yrs old and been in menopause for 8 yrs or so. I keep thinking these symptoms will go away but they actually may be worsening. I'll likely finish using the rest of this prescription but not renew it.”

5 / 10
Was this helpful?YesNo
Gee Gee January 18, 2019

For Atrophic Vaginitis: “I had great results after a few days of taking it but it has been 10 days now and I feel a “ itchy feel good sensation in my vagina “ I am worried I am getting a yeast now. Has anyone else experienced this. I am assuming it’s not just hormones making me feel fluttery in there. ”

8 / 10
Was this helpful?YesNo
Anonymous · Taken for 1 to 6 months June 30, 2019

For Atrophic Vaginitis: “I’ve been using this for a few months and am new to these type of products. This product gets all over your underwear even if you insert it before bed. You wake with it everywhere. I think more comes out than stays in. I’m going to ask for something else because I don’t think this really helps dryness.”

Was this helpful?YesNo
LeslieRose · Taken for less than 1 month February 12, 2020

For Atrophic Vaginitis: “I got bad migraine headaches on this medication. Imvexxy I was not able to work because of the headaches/nausea. I can't tolerate this medication. I was even on the lowest dose and it's still horrible. I will go to another option that is not hormonal. This stuff is vicious. If I could give it a Zero, I would.”

1 / 10
Was this helpful?YesNo
Disappointed · Taken for less than 1 month February 3, 2020

For Atrophic Vaginitis: “After the first dose, I felt a positive change and enjoyed careful intercourse. After the second dose, the discharge was significant and odorous. The day after the third dose and for the next three days, the itching and inflammation were unbearable. I would call the swelling an explosion. Time to try something else.”

1 / 10
Was this helpful?YesNo
Middle Age · Taken for 1 to 6 months June 18, 2019

For Atrophic Vaginitis: “I was prescribed Imvexxy and 1) it took too long to work 2) I had to endure additional testing because the Company that created it didn’t have the foresight to think that maybe they shouldn’t make the capsule pinkish which when dissolved and leaked on panties could be mistaken for spotting in a post menopausal female. How stupid! No thanks. My Dr. prescribed the Premarin cream for me instead. I only use a tiny amount 2x a week . Worked quickly. Not messy.”

1 / 10
Was this helpful?YesNo
monkeymomsc1 · Taken for 1 to 6 months March 21, 2019

For Atrophic Vaginitis: “Used Imvexxy before bed the first time and could tell a difference the next morning a HUGE improvement for me. I guess over time I hadn't realized how Sahara dry things were. Still new to it but haven't noticed any side effects thus far. HUGE HUGE difference”

Was this helpful?YesNo
Yamacl May 11, 2020

For Atrophic Vaginitis: “I didn't notice much if any improvement after 4 months of 10 mcg twice a week, but I stopped it as I noticed a quarter sized bald spot on the front of my hair that wasn't there before I started taking it. In fact, I have thick hair otherwise, and now there is hair all around this bald spot but it is smooth in the middle with no hair growth! : I don't know if it is from this medication but it seems to coincide with taking it and I don't take any other medications. Now I am concerned I won't get hair to grow back there, or if more bald spots appear. I am 54, and no family history of balding, both my mom and father in their late 70s have a full head of hair with no balding.”

2 / 10
Was this helpful?YesNo
Dee · Taken for 1 to 6 months June 6, 2019

For Dyspareunia: “I have taken Imvexxy for about five months. I took the 4 mcg and it helped. I probably should have taken the 10 mcg for painful sex. However, I had to stop using it-- pelvic cramping, breast tenderness, but the main thing that made me stop was my hair was falling out. I am sad because it was an easy fix for awhile.”

6 / 10
Was this helpful?YesNo
missy_65 · Taken for less than 1 month May 13, 2020

For Atrophic Vaginitis: “A friend recently told me about Imvexxy . I received my order via pill pack 3 weeks ago. Packaging was exceptional. Hormone quality even better than premarin. Had to stop taking premarin cream last year due to complications from the product. One happy customer here. And would most certainly recommend imvexxy”

10 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.