Skip to main content

Imvexxy and Hair Loss: What Users Say

Hair loss: mentioned by 10 users (14.1%)

Based on user experiences from 71 Imvexxy reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 16.9%
hair loss 14.1%
cramps 11.3%
hot flashes 7.0%
night sweats 7.0%
discharge 5.6%
itching 5.6%
migraine 5.6%
rash 5.6%
swelling 5.6%

Reviews for Imvexxy

Commonly mentioned side effects
  • Lea...
  • Taken for 6 months to 1 year
  • November 13, 2020

For Atrophic Vaginitis "I have been taking Imvexxy 10mg twice a week for about 10 months now. I had dryness on the outside of my personal area, more so than the inside dryness. I'm 64 with a healthy sex life. My husband thought it made me too lubricated and he didn't care for it. After two months, I noticed night sweats and some hair loss along with slight headaches. Mostly the night sweats were my big problem. I adjusted to 1 time a week of the 10mcg for a month, but still had night sweats. Now, I have been totally off Imvexxy for two weeks and noticed the night sweats have lightened up a bit. I am going to continue to stay off for 6 weeks to see if there is a big difference with the night sweats, hoping they disappear completely. I did not have this problem before I was on Imvexxy. The reason I was checking out these reviews was to see if anyone else had these same side effects. Please let me know if you do."

8 / 10
Was this helpful?YesNo
92 Report
  • Rel...
  • Taken for less than 1 month
  • November 4, 2019

For Atrophic Vaginitis "I can't believe how quickly this worked for me. I am using the 10mcg, and I noticed a big difference after one use. I never realized how bad my situation was until I realized I was moist and comfortable down there the morning after the first dose. (Sorry if that is TMI!) I was having terrible burning, itching, painful intercourse, and a feeling that I always had to urinate. I'm 47 and still menstruating, but my gynecologist recommended this drug. I haven't been using it for very long, but so far so good. I read the full insert and read two books (Estrogen Matters and The Estrogen Window) before deciding to take the plunge. I am still worried about the possibility of hair loss. Some users mentioned that side effect. For the record, I also have RA and secondary Sjogren's Syndrome. I take a lot of immunosuppressant drugs. I hate to add to the medication list, but I was absolutely miserable and getting frequent UTIs from the dryness."

8 / 10
Was this helpful?YesNo
82 Report
  • Kim...
  • September 16, 2020

For Atrophic Vaginitis "After dealing with atrophy following a total hysterectomy, my doc suggested Imvexxy. Let's start with the positives: It DID what it was supposed to do, painful sex vanished after using it only a week and a half and I felt better in the nether regions. Now for the 'not so' positives: I noticed my hair thinning and had a slight headache. In the second week, I noticed a rash on my arms (elbow down) and legs. My family doc treated me with steroids, but it started right back following treatment. I decided to stop Imvexxy on a hunch, and after nearly two weeks, the rash began to fade. When I mentioned this to my gyn, she said you must be allergic to coconut oil... I use coconut oil every day with no issues. The ONLY thing different before all this mess was starting Imvexxy. Bottom line, if anyone did have a rash after this medication and was told 'That's not the cause.' by their doc, you are not alone. I am trying another (non-hormonal) product as it had some good reviews... just to see."

4 / 10
Was this helpful?YesNo
67 Report

See also:

Frequently asked questions

  • Sas...
  • Taken for 1 to 6 months
  • February 13, 2020

For Dyspareunia "I have been taking Imvexxy 10 mg twice a week for 6 months now at night before bedtime. It has not helped at all with painful intercourse and dryness. My dr told me not to expect instant results and to try it for a few months. I had also hoped for at least a small bump in libido, but nothing. I usually get a slight headache the day after using, and there is some external burning as well. My hair feels thinner. I don't like having to insert the capsule manually; it's awkward and I never feel that I've inserted it far enough. Have not had any of it come out, though. I also feel that I may be starting a yeast infection. This is not for me, and I will discontinue after this month."

1 / 10
Was this helpful?YesNo
64 Report
  • Dee...
  • Taken for 6 months to 1 year
  • October 1, 2019

For Dyspareunia "I took Imvexxy for four months. It is an easy pill to pop in with little mess. However, I think the pill should be white because the pink discharge that you get from the pill could be confused with spotting. Anyway, the medicine worked right away for my pain with sex. However, I could not tolerate the pelvic cramping, breast tenderness, and hair shedding. I had to go off of it because I was too uncomfortable with these side effects. I am now on Estrace cream, and so far, no bad side effects, but the only downfall is that it is messy. Ugh. Nothing is ever a perfect fit :)"

5 / 10
Was this helpful?YesNo
53 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Yam...
  • May 11, 2020

For Atrophic Vaginitis "I didn't notice much, if any, improvement after 4 months of 10 mcg twice a week, but I stopped it as I noticed a quarter-sized bald spot on the front of my hair that wasn't there before I started taking it. In fact, I have thick hair otherwise, and now there is hair all around this bald spot, but it is smooth in the middle with no hair growth! I don't know if it is from this medication, but it seems to coincide with taking it, and I don't take any other medications. Now I am concerned I won't get hair to grow back there or if more bald spots appear. I am 54, and no family history of balding, both my mom and father, in their late 70s, have a full head of hair with no balding."

2 / 10
Was this helpful?YesNo
33 Report
  • Dee...
  • Taken for 1 to 6 months
  • June 6, 2019

For Dyspareunia "I have taken Imvexxy for about five months. I took the 4 mcg, and it helped. I probably should have taken the 10 mcg for painful sex. However, I had to stop using it-pelvic cramping, breast tenderness, but the main thing that made me stop was my hair falling out. I am sad because it was an easy fix for a while."

6 / 10
Was this helpful?YesNo
33 Report
  • Unh...
  • Taken for 6 months to 1 year
  • July 23, 2021

For Atrophic Vaginitis "IMVEXXY did not work for me. I'm 6 years post-menopause. Insurance quit covering Premarin cream (which worked great) and switched me to IMVEXXY. I tried the 4 & 10 mcg strengths. Neither took care of the dryness, irritation, or urinary symptoms. It caused a burning irritation that felt like a UTI after each use. I used it at night, and it was messy enough to require a panty liner. I also had some hair loss, which may or may not be related."

1 / 10
Was this helpful?YesNo
16 Report
  • Uta...
  • Taken for 6 months to 1 year
  • February 2, 2023

For Atrophic Vaginitis "Imvexxy has been effective in treating atrophic vaginitis. However, after having been on it for some time, I have gained nearly 10 pounds, experienced hair thinning, a 'full' abdomen, and thigh cramping, as well as my hot flashes have returned. Interestingly, the trials that were conducted for this medication only covered women for 12 weeks, so could side effects increase with long-term use? My insurance doesn't cover this medication, and I will be stopping it once I complete this month."

6 / 10
Was this helpful?YesNo
5 Report
  • Abb...
  • Taken for 1 to 2 years
  • June 2, 2023

For Atrophic Vaginitis "Just read all these reviews after having used this product for about a year and a half. I was on a strong dose at first, and it made me very crampy, so my doctor reduced the dose to 10 mg, which still seems like a lot compared to the reviews that I’ve been reading. I took it half as often as she suggested. It worked. However, I had the worst smell coming from my armpits, and I’ve never been a smelly armpit person, my hair is thinning, which I realize is a side effect according to the reviews, and I had weird sensations in my breast. So I will be discontinuing the use of this product. Good luck, ladies."

3 / 10
Was this helpful?YesNo
5 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.