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Viberzi and Severe Pain: What Users Say

Severe pain: mentioned by 8 users (3.7%)

Based on user experiences from 217 Viberzi reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 17.1%
constipation 13.8%
cramps 8.3%
gas 7.8%
bloating 6.0%
nausea 5.5%
stomach pain 5.1%
abdominal pain 4.6%
dizziness 4.1%
severe pain 3.7%

Reviews for Viberzi

Commonly mentioned side effects
  • Xqq...
  • Taken for less than 1 month
  • May 31, 2016

For Irritable Bowel Syndrome with Diarrhea "This product needs to come off the market! I landed in the hospital for 4 days with severe acute pancreatitis, renal failure, liver hepatitis, Oddi spasm, etc. I am a 38-year-old female, I don't drink or do recreational drugs. After taking this, my liver and pancreatitis enzymes were over 10x the norm. I had L10 stabbing pain within 20-30 minutes of taking Viberzi for the first time. I thought I was dying, I could barely breathe, and I buckled over in pain. I took antacid thinking it might help, but it didn't, and with time, the pain transformed to my mid-back. My entire GI felt like it was on fire, and if my belly got touched, it would bring me to tears. A fever started a few hours later. I have had a much milder pain belly reaction to Vicodin/Oxy, but never like this."

1 / 10
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38 Report
  • Rho...
  • Taken for less than 1 month
  • December 9, 2016

For Irritable Bowel Syndrome with Diarrhea "I wish there was a way to give this a negative number. I've had IBS for 14 years since having my gallbladder removed. I took the initial dose of this, and not two hours later, I was doubled over with severe pain right beneath my ribs. When the muscle spasms started, I went to the ER. I was admitted with pancreatitis and liver enzymes 10x normal. I spent 4 days in the hospital until my numbers were back to normal. I could not believe a pill could do this much damage in such a short time. Very scary!"

1 / 10
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31 Report
  • mcg...
  • Taken for less than 1 month
  • June 10, 2016

For Irritable Bowel Syndrome with Diarrhea "I have had IBS-D for 20 years, but controlled with Imodium and Bentyl. Three years ago, it was uncontrollable. Could not leave the house. Stool cultures, colonoscopy, blood work, x-rays, and scans due to pain all negative. Imodium didn't work. Doctor termed it as unspecified colitis and IBS-D. Now taking Lomotil, hyoscyamine, Donnatal, and cholestyramine. This makes life bearable. Tried Xifaxin and it did nothing. Now got the 100 mg Viberzi 2x daily. Took one pill with food yesterday morning. Within 15 minutes, my legs turned to rubber, heart was racing, cold sweat, and difficulty breathing. The heart racing and breathing went away within half an hour, but the rubber legs lasted about five hours. Severe abdominal pain, gas, metal taste till last night. No more."

1 / 10
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31 Report

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Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • August 9, 2019

For Irritable Bowel Syndrome with Diarrhea "I gave Viberzi a 5 because yes, it did work. My diarrhea did slow down, and on most days, it stopped completely. My cost with the copay card was only $30, so that’s not bad either. My side effects were really bad though. Increased need to urinate all day and night. I ended up with a bladder infection. I also had night sweats and severe abdominal pain and gas. I would say it’s worth it to try it. Not everyone has the same side effects."

6 / 10
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16 Report
  • Jen...
  • February 1, 2017

For Irritable Bowel Syndrome with Diarrhea "I took it for about 2 weeks, and one night I woke up around 2:30 am with severe pain that radiated to my back, with heavy puking and pooping. Went to the hospital, and they told me I had pancreatitis and took me off Viberzi. Spent 6 days in the hospital with IV fluids and no eating. Horrible experience!"

1 / 10
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20 Report

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  • Ano...
  • January 26, 2017

For Irritable Bowel Syndrome with Diarrhea "I was put on Viberzi. Took one pill before bed on Tuesday and one before bed on Wednesday, 75mg each. To say this has been a nightmare is an understatement. Within an hour of the second pill, I had severe abdominal and back pain. Also, pain that went into the right side of my chest. It is 12:00 Thursday, and I haven't taken another pill, nor will I, but I am completely worn out and still in full pain throughout my body. I was so hopeful for this. Be careful!"

1 / 10
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20 Report
  • Gab...
  • September 28, 2016

For Irritable Bowel Syndrome with Diarrhea "I have been dealing with IBS-D since I was about 13 years old - I am now 25. The uncontrollable cramping and diarrhea gave me no quality of life. I wouldn't leave my house or do anything. What kind of life is that for a young adult? Back in December 2015, my doctor told me about Viberzi. This has been a GODSEND medicine. I have my life back!! The second week I started taking it, though, I woke up in excruciating pain. I went to the ER, and I had a spasm of the sphincter of Oddi. I stopped Viberzi for a few days, then went on the 75 mg, and I take it once a day. I FINALLY can live a normal life and not worry every 5 seconds about where the bathroom is."

10 / 10
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15 Report
  • Anonymous
  • Taken for less than 1 month
  • April 23, 2016

For Irritable Bowel Syndrome with Diarrhea "Took 1 dose and landed in the hospital with severe pain."

1 / 10
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29 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.