Doxylamine / pyridoxine and Vomiting: What Users Say

• Kar...
• May 10, 2020

For Nausea/Vomiting of Pregnancy "I started having extreme nausea and vomiting at around 6 weeks pregnant. There was a point where just thinking about food would make me nauseous. Obviously, I had to force myself to eat because of the pregnancy, but I knew it wasn't going to last, I just threw it back up. I would vomit 2 times a day and feel nauseous the whole day. My OB told me about Bonjesta, I would take anything at this point. Turns out my insurance didn't cover it, it would be $700+ out of pocket. I literally started crying because I was so tired of feeling the way I was feeling. But luckily, I got a prior approval, and immediately after taking it, I was able to keep my dinner down for the first time. I am on day 3 and currently have not thrown up or experienced nausea like I had been. It does make you really tired, but I'd rather feel tired and fight through it than be nauseous all day and have the horrible feeling of hunger but not eat from fear of throwing up."

• Mam...
• September 11, 2018

For Nausea/Vomiting of Pregnancy "I have hyperemesis gravidarum (HG)! Have had it with all 6 pregnancies. My last pregnancy (my 5th), my doctor gave me Diclegis, and it changed my whole pregnancy experience! In my previous 4 pregnancies, I suffered for 5-6 months, constantly puking, weak, fatigued, can't get out of bed, can't keep food or water down. In fact, I have been hospitalized with every pregnancy for dehydration and was admitted for 3-5 days where they pumped me up with Phenergan and Zofran (other nausea meds). I would feel a little better, but the nausea was never gone! After my first dose of Diclegis, I immediately felt a difference! Let me be clear, this is the only thing that has ever really helped take away the vomiting and nausea EVER. I've tried everything! During my 5th pregnancy, when I started taking Diclegis, it was the first time I felt relief. I am now pregnant with my 6th child, and I have started Diclegis again because at 6 weeks I'm so sick with nausea and vomiting I can't get out of bed!"

• Mar...
• Taken for less than 1 month
• April 22, 2020

For Nausea/Vomiting of Pregnancy "I am 9 weeks pregnant and have had horrible nausea and sometimes vomiting. Zofran helped, but is linked to heart defects in the babies, so I was put on Phenergan, which helped but still didn't stop the nausea, which is when my OB put me on Bonjesta. Turns out, I had no idea what nausea, dizziness, and gut-wrenching vomiting were until I started taking this medication! It made my symptoms so much worse. I've heard good things about it but want to let people know it does not work for everyone! I have settled on Phenergan, it keeps my nausea at a reasonable level, and I rarely vomit. Please stop taking Bonjesta if you're getting dizzy and sick to your stomach!"

• Bri...
• Taken for 1 to 6 months
• December 16, 2017

For Nausea/Vomiting of Pregnancy "So I suffer from hyperemesis gravidarum (HG) (severe nausea and vomiting). I was prescribed Zofran with my first pregnancy, and the birth defects that were listed that could affect my baby affected my baby. I was so angry and upset with my doctor for telling me it was safe to take. My daughter now has a heart defect. Second pregnancy, I suffered so much more than my first. I found a new OBGYN, and he prescribed me Diclegis. I will say this: it’s a lifesaver. I was vomiting 20-25 times a day, and the nausea never went away. I couldn't drink or eat anything, I lost 15 lbs in 3 weeks. This drug is the only thing that is safe during pregnancy, and it was the only drug that works. I would only recommend this to anyone that suffers from HG."

• Aly...
• May 3, 2019

For Nausea/Vomiting of Pregnancy "Bonjesta helped immediately. After dealing with nausea and vomiting starting at week 5, I realized it would have been impossible to get myself out of bed and into work. I wasn’t able to keep water down. Was dehydrated. Weak. My doctor prescribed this immediately, and it got rid of probably 90% of the nausea and vomiting."

• My...
• Taken for less than 1 month
• August 15, 2017

For Nausea/Vomiting of Pregnancy "This drug has saved me from going insane because of how ill I was. I suffered from severe nausea and vomiting in pregnancy. Throwing up for weeks on end, I would throw up every few hours. I went days without being able to keep anything down, including water. Those who suffer from NVP, I know your suffering... it is so awful! I was stuck on the couch and in bed for over a month, and then I finally decided it was time to go on medicine. My quality of life was 0 before this medication. This medicine is definitely on the spendier side but worth every penny if you are suffering. If this medication didn't exist, I would no doubt be in the hospital."

• Pas...
• June 21, 2016

For Nausea/Vomiting of Pregnancy "I have always been sick with each pregnancy and was put on Zofran. It worked sometimes. I have been taking Diclegis for about a month, and it works the same as Zofran for me. Sometimes it works, other times it doesn't. I am up to four pills per day. Sometimes I still throw up and feel nauseous - like today. I guess the best thing for me is to get my tubes tied. I can't deal with this whole pregnancy thing ever again. I know one thing for sure: this is the very last pregnancy for me."

• Hou...
• Taken for 1 to 6 months
• May 17, 2015

For Nausea/Vomiting of Pregnancy "I am thirteen weeks pregnant and have been taking this medicine since 6 weeks. At first, I didn't notice any difference, but one day my nausea disappeared. Completely! I thought that the medicine had nothing to do with it since I was sick for two weeks while taking it. Three times I have forgotten to take it and spent the following day puking. This medicine has given me my life back. I have two younger kids at home, and I don't have the time to be sick."

• 2nd...
• Taken for less than 1 month
• August 24, 2014

For Nausea/Vomiting of Pregnancy "I'm 4 months along with my second child. This pregnancy is very different from the last. I never had such bad nausea, vomiting, and dry heaving. I'm taking this medicine on an as-needed basis. So far, I need one pill at night and another about mid-morning. The original prescription said one in the morning, one in the midday, and two at night. I did that once and slept until 2 pm the next day. That's not healthy either. The only complaint I have is the cost. It ran $178.53 for us. A cost that wasn't expected, but when Phenergan and Zofran aren't working.... you give in. Just as every OTC or prescription, there are side effects. For me, the benefit outweighs the risk. Try to stay away from medication until at least 13 weeks."

• 2nd...
• Taken for less than 1 month
• August 24, 2014

For Nausea/Vomiting of Pregnancy "I'm 4 months along with my second child. This pregnancy is very different from the last. I never had such bad nausea, vomiting, and dry heaving. I'm taking this medicine on an as-needed basis. So far, I need one pill at night and another about mid-morning. The original prescription said one in the morning, one in the midday, and two at night. I did that once and slept until 2 pm the next day. That's not healthy either. The only complaint I have is the cost. It ran $178.53 for us. A cost that wasn't expected, but when Phenergan and Zofran aren't working.... you give in. Just as every OTC or prescription, there are side effects. For me, the benefit outweighs the risk. Try to stay away from medication until at least 13 weeks."

• Col...
• August 3, 2015

For Nausea/Vomiting of Pregnancy "I lost 15 lbs due to nausea and vomiting since my 7th week of pregnancy. I was vehemently against taking any medication, but after I researched this medication, I felt that it was as safe as a medication can be during pregnancy. I was at risk of losing my baby due to the significant weight loss, so I am grateful for this safe, completely effective medication. It is working for me at the lowest dose, and I feel I should buy stock in the company selling this wonderful drug. I am able to eat, drink, and maintain a normal lifestyle after weeks of misery. I highly recommend this drug if the traditional methods of managing NVP are not effective for you. I was lucky enough to receive samples from my OBGYN, so I cannot say anything as to cost."

• Pre...
• Taken for less than 1 month
• January 20, 2021

For Nausea/Vomiting of Pregnancy "Well, I came to the comments hoping it wasn’t just me, haha! I started Bonjesta at 13 weeks, and honestly, I passed out the first night (can’t have nausea if you’re knocked out), so now I’m on day 4. It doesn’t put me out, but it’s like it amped it up. I’ve thrown up 3-4 times a day, and as soon as I put food on my tongue, I get gaggy and chills and end up not eating. I’ve been living on crackers and chips, then I throw those up. I tried a smoothie yesterday and ended up puking it all back up. Please tell me it’s almost over, lol."

• Pre...
• Taken for less than 1 month
• January 20, 2021

For Nausea/Vomiting of Pregnancy "Well, I came to the comments hoping it wasn’t just me, haha! I started Bonjesta at 13 weeks, and honestly, I passed out the first night (can’t have nausea if you’re knocked out), so now I’m on day 4. It doesn’t put me out, but it’s like it amped it up. I’ve thrown up 3-4 times a day, and as soon as I put food on my tongue, I get gaggy and chills and end up not eating. I’ve been living on crackers and chips, then I throw those up. I tried a smoothie yesterday and ended up puking it all back up. Please tell me it’s almost over, lol."

• meg...
• January 2, 2016

For Nausea/Vomiting of Pregnancy "This is my first pregnancy and have been in the hospital twice, and I'm only 8 weeks. I have never been so sick in my entire life, one day I vomited for 16 hours every 15 minutes. Finally, this was prescribed to me, and I started the night I was discharged, and I have not even felt sick one bit. I was doing over-the-counter B6 and Unisom, but it did not seem to work for some reason. This pill is amazing, and I would recommend it to anyone else who is suffering as badly as I did."

• Lyn...
• September 8, 2015

For Nausea/Vomiting of Pregnancy "I have been so sick since becoming pregnant, vomiting several times per day. Initially, I was given Zofran, but the minute it would wear off, I'd start vomiting again. My doctor switched me to Diclegis a few days ago and I feel great! No vomiting, no nausea, and I'm not worried about the potential problems that extended use of Zofran could cause anymore."

• Bec...
• Taken for 1 to 6 months
• January 23, 2020

For Nausea/Vomiting of Pregnancy "I had pretty bad morning sickness starting around my 6th week of pregnancy. I got to where I dreaded waking up the next day because I knew I’d be super nauseous and sometimes vomit. At my first appointment at 8 weeks, I told the doctor I was experiencing nausea and vomiting, and he prescribed me this, and it’s an absolute godsend! Taken at bedtime, I felt much better the next day! You don’t have to worry about this drug because all it is is a high dosage of Vitamin B6 and Unisom. I’m now 27 weeks and still taking it every night because I’ve been feeling good and am scared to stop it and be sick again! Lol. I tried stopping it early in the 2nd trimester but promptly vomited throughout the day, so I plan on continuing to take it because my doctor said it is safe to do so."

• Fir...
• Taken for less than 1 month
• July 16, 2015

For Nausea/Vomiting of Pregnancy "I have been taking Diclegis for 2 weeks now, and I feel amazing. Taking 3 pills a day seems to be the magic dose for me. I previously tried Zofran, which helped minimally, but I was still nauseous and vomiting violently a few times throughout the day. I work full time, so I really needed something more effective, so my doctor recommended I try Diclegis. Two thumbs up, just a little pricey."

• Hum...
• August 5, 2020

For Nausea/Vomiting of Pregnancy "So, the first time I took Diclegis, I was around 8 weeks pregnant, and it worked wonders. I couldn’t relate to negative feedback here, but now with my second pregnancy, it doesn’t work like the first time. I still throw up, I’m still nauseous, I hate the smell and sight of food, but I’m not going to say I’m as miserable as I was with my first pregnancy without this drug. Maybe because I’ve been here before, I know what to eat and what to avoid, or maybe it’s Diclegis working 20 percent only. I hate to say this, but ladies, it doesn’t work every time."

• Dan...
• Taken for 1 to 6 months
• September 19, 2021

For Nausea/Vomiting of Pregnancy "10/10 I've had terrible nausea and vomiting since week 6, currently in week 11. Two nights ago, I forgot my pill ONE night, and the next AM, projectile vomiting. What does this tell me? This WORKS, and I will make sure I don't miss another dose as I feel great when I do take it."

• Dan...
• Taken for 1 to 6 months
• September 19, 2021

For Nausea/Vomiting of Pregnancy "10/10 I've had terrible nausea and vomiting since week 6, currently in week 11. Two nights ago, I forgot my pill ONE night, and the next AM, projectile vomiting. What does this tell me? This WORKS, and I will make sure I don't miss another dose as I feel great when I do take it."

• kim...
• August 23, 2015

For Nausea/Vomiting of Pregnancy "This medication works wonders! I can take it without having to eat something before, which was so helpful, considering I couldn't hold any food down! I lost more than 20 lbs due to vomiting and nausea. And getting into a moving vehicle was the worst! I take one in the morning and I feel good all day! I love it so much, lifesaver."

• Lif...
• August 30, 2016

For Nausea/Vomiting of Pregnancy "I have been taking Diclegis since I was 11 weeks pregnant. Prior to that, I was vomiting maybe twice a day and felt nauseous all day long (except at night). The first time I took Diclegis, I was in HEAVEN!! I felt so good. I was able to go a full day not even thinking about feeling sick. I thought that would be the effect the whole time. Not! I am 3 weeks in with taking Diclegis, and it seems like the effect of it has worn off to a certain extent. I am back to feeling nauseous most of the day. I will say that the vomiting is still under control, but I vomit maybe once every 4-5 days (which is still progress). I am in my 14th week now, and I want to see how I will feel if I don't take the meds, but I'm scared, lol!"

• Anonymous
• Taken for less than 1 month
• October 6, 2017

For Nausea/Vomiting of Pregnancy "This medicine works wonders! I was having severe nausea and vomiting every morning to the point I was losing so much weight. My doctor prescribed me Diclegis. I take 2 at night and one during the day because of how tired it makes me. Ever since I've been taking it, I've been able to hold down food and water, and I've also gained an appetite. Without these, I wouldn't be able to go to work. I love them!"

• Dom...
• Taken for less than 1 month
• September 25, 2019

For Nausea/Vomiting of Pregnancy "Saved my life is an understatement. I suffered so badly with morning sickness with my first daughter, and Zofran didn’t work at all. I was sick the whole 8 months. With this pregnancy, I experienced HG again, but this medicine literally gives me my life back. It does make me a little sleepy, but I’ll take sleepy over nonstop heartburn and vomiting any day."

• Mrs...
• May 26, 2020

For Nausea/Vomiting of Pregnancy "I take one Bonjesta pill at night before bed. This medication is the only medicine that has helped with my extreme morning sickness. When I take the pill at night, I feel less nauseated in the morning. I can eat more, and I am not vomiting as much. I feel more like myself. I went from being sick 100% of the day to 20% or less some days. Definitely worked for me."