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User Reviews for Doxycycline to treat Bacterial Infection

Also known as: Vibramycin, Oracea, Monodox, Doxy 100, Adoxa, Doryx, Avidoxy, Targadox, Acticlate, Alodox, Uracil, Doxy-D, Oraxyl, Doxy-Caps, Morgidox, Adoxa Pak, Adoxa TT, Adoxa CK, LymePak, Mondoxyne NL Okebo Doxy 200 Doryx MPC …show all brand names

Doxycycline has an average rating of 4.8 out of 10 from a total of 165 ratings for the treatment of Bacterial Infection. 33% of users who reviewed this medication reported a positive effect, while 48% reported a negative effect.

Doxycycline Rating Summary

4.8/10 average rating

165 ratings from 175 user reviews.

Compare all 1055 medications used in the treatment of Bacterial Infection.

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Reviews for Doxycycline

CDassler46 July 19, 2021

“I woke up Friday with a minor intermittent ache in my upper canine tooth. I figured that it could wait until Monday. By Saturday morning the swelling in my cheek was the size of a golf ball. Anyhow, being the weekend I was unable to get ahold of the dentist. I had nobody to drive me to the ER, and there is no way that I could have driven myself in that kind of pain, so I decided to take some Doxycycline that I had. I started off by taking two pills then followed the directions on the bottle of two pills once a day. This pain became so bad that I felt myself on the verge of literally passing out from it. By sunday AM the swelling had increased to where my eye was swollen shut. I was finally got a ride to the emergency room. A few hours after a dose of corticosteroids and a dose of Clindamycin, I feel much better. The Doxycline did nothing for this infection. Not even slow it down. If a doctor tries to prescribe this to you for a tooth abcess, demand something else.”

1 / 10
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Dee · Taken for less than 1 month March 9, 2021

“I took this for 7 days. On day 6 I woke up to swollen eyes/puffy eyelids and uncomfortable pressure in my head. It’s been one week off them now and I still have the pressure in my head. My head feels really off...not right. I also had the bad reaction to sun(rash.) Got tingling in my face as well. I’ve taken many antibiotics and this has been the worst by far. :(”

1 / 10
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Helen Kae February 26, 2021

“Took doxycycline for 10 days for a sinus infection. It did absolutely NOTHING but cause severe head aches. 4 days after finishing the antibiotics and I was still sick with the sinus infection. Got put on Augmentin and literally after 1 day feel SO much better. Doxy is useless against sinus infections.”

1 / 10
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Dolly · Taken for less than 1 month January 5, 2020

“I was terrified of taking this medication due to the reviews here which are so scary but had to take the medication for chronic sinusitis that was the worst for me. DO NOT let these reviews deter you as I had no side effects only that I had to eat before taking the meds..just a cracker will do even, to stop nausea. I was feeling so much better in just two days but kept taking my 14 day course to complete. I am allergic to penicillin and usually get many side effects listed on medications BUT NONE FROM THIS. I had headache anyhow from the sinusitis so just took a paracetamol as well as the doxy which is allowed and this sorted me right out. Should you be prescribed doxycycline then take it and do not worry about all the bad reviews just get better.”

10 / 10
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phishon · Taken for less than 1 month January 15, 2020

“No side effects at all. I am not sure what all the negative reviews are about. If you're having an allergic reaction that is different. Allergic reactions are not the drugs fault, the reaction of your body to the doxycycline, but you should definitely stop if you are showing signs of allergy. It worked great for me. Started to feel better in a couple of days and was completely better in about 4 days. I took the full course as directed.”

9 / 10
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Anonymous February 15, 2014

“This is the only medicine that helps get rid of my sinus infections and it looks like that goes for a lot of other people too. This is the only antibiotic that I can take because I am allergic to so many others.”

10 / 10
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Pennylock · Taken for less than 1 month May 29, 2020

“Had extreemly painful sinusitis. Had been given 2 lots of Amoxcillin which didn’t work . Given a 7 day course of Doxy .2 capsules to take on the first day ,then one a day This worked and I did not suffer any side effects at all . Would definitely take this again .”

10 / 10
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Frequently asked questions

Allmansfan · Taken for less than 1 month June 16, 2020

“cat scratch fever is not just a Ted Nugent song, I got it and it sucks. This medicine definitely works, and fast in my case. HUGE NEGATIVE is I cannot stomach the doxycycline. I am constantly nauseous, I eat breakfast before my morning dose, lots of water, and still suffer extreme nausea. After day 2 I was struggling to eat breakfast I'm trying to stick it out 4 more days, but I'm struggling.”

8 / 10
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Snm55447 · Taken for less than 1 month November 12, 2013

Vibramycin (doxycycline): “I was diagnosed with a bacterial sinus infection and was prescribed this antibiotic, due to being allergic to amoxicillin. The pills are 100 mg each I am to take twice daily. At this time many of my sinus symptoms have dissipated which is an excellent sign that i'm finally on the mend. I haven't had any side effects with this, and have taken as directed. Avoiding dairy products, not laying down 30 minutes after ingesting, and making sure to take it with food and a large glass of water.”

8 / 10
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pinklove72 April 8, 2015

“Every time I get a sinus infection I ask for Doxy it clears me up in a few days. I don't have any bad side effects, guess I'm lucky. I would recommend this medicine highly for sinus infections since it works so fast. I have to work and don't have time to be sick, I'm also a single mother and can't be down too long and this medicine never let's me down!”

10 / 10
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debbie · Taken for less than 1 month November 10, 2019

“I went to walk in clinic for sinus infection. I was given this medication doxycycline for the 1st time. I will never get accept a prescription for it again. On antibiotics I usually I feel better in a day or 2. On doxycline it took at least a week before symptoms started to clear up. I have been tired and had a severe head ache since I got the med. My body hurts and I still have the infection. I have taken the meds for 8 days. I am not taking the last 2 days, the pressure in my head is so bad I'm afraid it may give me a stroke. I have no idea why the walk in clinic gave me this medication if the side effects are so bad. But I took it, but never again.”

3 / 10
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nightbird7 September 23, 2019

“I was prescribed doxy because of an allergy to penicillins. I did have the headache on this. My infection is better, have I had some crusting sores that had not been healing that are now better. Also a couple of sore teeth are no longer sore. I read up on how to take it as I wanted it to work - be sure not to eat for 2 hours before or an hour after for best absorption. Drink 8 oz of water with it - this does help to wash it down and with any stomach issues after. Don't lie down for at least 30 min after, preferably for up to an hour after, as it can cause esophageal irritation if you lie down. If you take any supplements containing calcium or magnesium, take those several hours after your last dose of doxy as they interfere with it. If you feel a little queasy after taking it, drink more water and wait a bit before trying food as a remedy.”

8 / 10
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MerlinPhD · Taken for less than 1 month February 23, 2015

“Doxyclycline has been the only antibiotic that has helped me consistently clear my severe sinusitis with excessive catarrh and phlegm (even when I was told it was viral) - over 15 years. Once every couple of years or so I have had infections that simply don't clear without help. I have been prescribed many other antibiotics and all that happens is I have to finish the unhelpful course (with no result) and then use Doxycycline. Over years, I have endured the ridicule of several doctors who explain how this cannot help me - I then have to find a doctor who listens - then I can breathe again.”

10 / 10
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Keleeemo · Taken for less than 1 month May 28, 2015

“I started on Doxycyline a few days a go after a week of headaches and painful sinuses. I was running a low grade fever and coughing up phlem like crazy. Every part of my body hurt from the fever. Once starting doxy taken with a full glass of water, no vitamins and no laying down for 30 minutes I started to get better. I had a few graham crackers so I didn't take it totally on a empty stomach. My fever broke and the headaches are gone. I had many sinus infections until having surgery on them for a drainage issue 20 years ago. I never had another one until this year and it's a doozy. Doxycycline is the only thing that works for me on these sinus infections.”

10 / 10
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liberty_sm December 7, 2013

“Had really bad sinus infection, tried Augmentin - didn't help. After that my dr prescribed Ambroxol AL (available in Germany - combination of ambroxol hydrochloride (secretolytic agent for mucus) and doxycycline 100 mg - after only two days I started feeling much better - my nose and ears were clear and I felt much better in general. No side effects, since I took it after meal (not on empty stomach).”

9 / 10
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Dee · Taken for less than 1 month October 16, 2019

“I took doxycycline for 4 days. Then I felt dizzy, blurred vision, forgetful. Ended up in hospital because I felt like I was drunk!! I couldn't even remember going to ER. Couldn't walk, couldn't answer questions. They said this pill doesn't have a side effect like that. I beg to differ. I lost 2 days of memory bceause of this drug. They need more research.”

1 / 10
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Everything hurts March 7, 2019

“Went to a new doctor for a sinus infection as I just moved into a new area. I've always used amoxicillin as I prefer no side effects or drowsiness. This doctor refused that completely and said I need a nasal spray and he would only give me and antibiotic if I got the nasal spray too, okay whatever I'll take both. I go to the drugstore, where the nasal spray cost me $50... And I find out he didn't give me a prescription for amoxicillin. He prescribed me this doxycycline. Well, I am on day 3 and let me tell you. Not only has my sinus infection NOT gone away, it has gotten so bad that I can barely hear and the infection is so bad that all my teeth hurt on the top of my mouth! I have the worst headache. I haven't been able to sleep for 2 nights, I'm high, I can't breathe, I'm sick, I'm in pain everywhere, chills, and I now have a throat and chest infection. I'd cry but I'm so out of it I can't. I feel helpless and afraid. This is the most awful medication I have ever taken.”

1 / 10
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Coco · Taken for less than 1 month November 3, 2019

“I started taking this drug and instantly felt nauseous and fatigued to the point where I could not get out of bed. I started taking probiotics with it which helped with the physical side effects, but the mental side effects were unbearable. I started off feeling extremely depressed, and then came intense waves of anger and anxiety. By my 6th day taking it, I had lost all memory of an entire day and on the 7th day, I was so low. Luckily, I stopped taking it after the intense dark thoughts. It has been 2 days since I took the antibiotic and I feel completely normal again. This drug is evil for anyone susceptible to mental health problems - do not take it!!!!”

1 / 10
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alex November 10, 2019

“I told the P.A. that I was on my last pill for Zithromax . She told me that I need to stop taking it and start taking this poisonous ATB (doxycycline) .After the first pill ,I started experiencing diarrhea ,the second time ,it got worse that I had to go to the bathroom every 15 mins during the night .I was physically and mentally drained the next day ,but forced myself to work. To make matter worse, my respiratory infection exacerbated and developed hoarse voice. It has been 3 days ,since I took the 2nd pill and still going to the bathroom every 20 mins. Yesterday I took lomotil to control the urge for when I was at work. I ate lots of bananas ,white rice etc ,but to no avail. Now my anus is so irritated. Who ever ,prescribed this for bacterial infection should be told they have violated their oath of " DO NO HARM !"”

1 / 10
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Super5678 · Taken for less than 1 month January 16, 2020

“I had a bacterial infection Ureaplasma Urealyctum and was definitely hesitant to take this doxycycline pill due to the nasty reviews. The first time I took this medication it was terrible but that was because I took it on an empty stomach. It takes about 30 minutes to kick in and if you haven't eaten it will be miserable but once I ate 30 minutes prior to taking each pill, I didn't experience any nausea or vomiting.”

7 / 10
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Tleary · Taken for less than 1 month December 13, 2018

“Took this after a round of Amoxicillin for sinus and tooth pain, the Amox did not do much, but the doxy did. It also changed my digestion for the better and still cannot figure out why, totally unexpected result . My sinus headache and tooth pain cleared. Must be something in the gut it gets rid of also. I have experience no side effects whatsoever. I now have no bloat, pain, or anything in the gut, and can eat anything again without symptoms. Before I couldn't eat pizza, salads, dressings, cheese, mushrooms, spices, pickles, steak and sauces, without problems now I am all good - what gives? I have had gut pains for years, but recently no more. Strange, very strange. If I pass today, I was wrong, but not yet.”

10 / 10
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Miranda March 11, 2020

“I never thought I would review a medication, but here we are. That's how BAD this stuff is. This medication ruined my life. I had a rash. Third day in, the rash started going away. But I would've rather had the rash. I've never had anxiety in my life & this made my heart rate around 110 BPM. I'm usually 55 BPM. It made my head RACE. I was convinced I had leukemia & it was end of me, I couldn't breathe, I would burst into tears in the middle of volleyball games & cry all night. Thoughts of everyone I love dying were frequent. Googled the side effects & saw anxiety as a symptom. Even if you've never had anxiety, & you think side effects are bogus, take this one seriously. I begged my doctor to mark to never prescribe it to me ever again. Take this with food! I didn't one morning & got very sick in my car on the way to work. A week off now & I feel good. I was on it for 2 weeks, it took 5-6 days to fully exit my body due to its half-life. Ask your doctor questions. This is no joke.”

1 / 10
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De · Taken for less than 1 month March 11, 2020

“Doctor prescribed doxy for sinus infection. After 3 days, I am experiencing huge headaches, stomach pain and muscle pains. Am stopping this medication now. The pain it is causing me isn’t worth taking any more.”

1 / 10
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3 days on the medication January 5, 2020

“I was prescribed 7 days of 100mg, first day taking 2 pills for a sinus infection. I took the first dose as directed with a glass of water and within an hour was doubled over in pain, nauseous and dizzy Day 2 I felt a lot of pressure in my head, especially the right side of my head, really bad ringing in my ears and feeling like my ears would pop/burst. Today I woke up with a stiff neck and joints with the right side of my neck really tender to touch and feeling extremely tired. I took the medication after a full breakfast and started feeling so much pressure in my head, ears ringing extremely loudly, anxious to the point of what feels like a panic attack. My hands and arms also felt what’s best described as light and tingly. I threw the medication up today on purpose to get it out of my body and thankfully I had it with a large meal. The rest I have thrown away. I’d rather be sick than take this medication.”

1 / 10
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bigjohns747 March 6, 2009

“I've been sick for 3 years with a sinus infection, bacterial infection, middle ear infection, respiratory infection and so on - (was working in the Drains) - couldn't get rid of it. Have too to date (with Proof) 400 prescribed tablets from the doctors, (not including all the off the shelf one's I got myself (another 3/400). Anyway to cut a long story short, I have been on these doxycycline tablets for 2 weeks now (100MG a day) and am feeling a lot better. It's breaking down all the mucus etc. I can smell again now so if you have a massive sinus infection GET THIS - IT WORKS.”

10 / 10
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Starrr · Taken for 6 months to 1 year July 17, 2014

“This is the only medication that actually can clear the infections I get in my jaw and teeth, it works fast and really good, but the side effects can be unbearable at times. Extreme nausea, vomiting are the worst. The only way I've found to sometimes help with the vomiting is to take with a meal, which works most of the time, but not always.”

10 / 10
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Dukie · Taken for less than 1 month March 24, 2019

“I have been on Doxycycline for 4 days, in conjunction with an expectorant, for a sinus infection. Script is for 10 days. I have followed "how to use this medication" received from the pharmacy, including drinking non caffeine drinks and have had no negative interaction with this medication. As a matter of fact my symptoms broke today but as with any medication even though I am feeling better I will complete the 10 day round of this antibiotic. I am allergic to penicillin and diagnosed with epilepsy and find this antibiotic one of the best I have taken and have not had any med interactions. In addition to medication rest and plenty of fluid assist in recovery.”

10 / 10
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Axethrower · Taken for less than 1 month February 12, 2020

“I have a bad sinus infection so I called my doc who I see weekly because my bp and they gave me this. With in 20 mins of my first does the sinus pressure became beyond extreme, I became dizzy, extremely hot sweating (it’s cold where I live) and I blared my air conditioner, and so nauseous I puked. Now after vomiting it’s still intense and had to take a migraine pill and an anti nausea pill. If you have a sinus infection stick with the Amoxicillin clav. This pill IS AWFUL”

1 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.