Skip to Content

User Reviews for Diphenhydramine

Also known as: 40 Winks, Aler-Dryl, Aler-Tab, Alka-Seltzer Plus Allergy, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, ...show all 97 brand names

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Diphenhydramine.

Filter by:

User Ratings

10
   
36%(6)
9
   
18%(3)
8
   
12%(2)
7
   
6%(1)
6
   
0%(0)
5
   
6%(1)
4
   
6%(1)
3
   
6%(1)
2
   
6%(1)
1
   
6%(1)

Diphenhydramine Rating Summary

7.4/10 Average Rating

17 Ratings with 16 User Reviews

What next?Compare all 217 medications used in the treatment of Nausea/Vomiting.

Reviews for Diphenhydramine to treat Nausea/Vomiting

Sort by:

Benadryl (diphenhydramine): "ER gave me 25mg diphenhydramine IV for nausea. The only effect was delirium and a brief medication nap. I felt woozy and poisoned for at least two hours afterwards. It may work for others, but it certainly didn't help me."

   
3.0

Simon Charles (taken for less than 1 month) September 14, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I take Methotrexate weekly 25mg and have found that taking Benadryl at dose and 12 and 24hrs after my weekly dose help reduce the nausea"

   
8.0

Anonymous September 2, 2017

1 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"I took diphenhydramine by mouth for spring allergies. It made me drowsy and helped my allergies, but also made me dizzy and nauseated, which it is supposed to prevent. I do know that it is probably one of the best antihistamines on the market."

   
1.0

Mitch1951 (taken for less than 1 month) February 22, 2017

1 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"If you got a migraine cocktail in ER, then the med that gave you the anxiety, was most likely the compazine, it makes you feel very anxious that's why they give the benadryl with it to counteract the side effect of anxiety. (migraine cocktail consists of benadryl, compazine and depakote or Solumedrol). I had to take more benadryl to get rid of the severe anxiety"

   
9.0

sylviasylvia2 (taken for 1 to 6 months) February 21, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"Like others here, I discovered using diphenhydramine for nausea when I had to take pain killers in the hospital. My nurse explained why to me. But since, I have found that if a drug of any kind gives you nausea, or in fact if you have nausea at all, give it a try. Last week, I had a fit of nausea that I can't track to any new Rx, it just seemed to occur on its own. I took the OTC diphenhydramine and it went away. When I went to my doctor complaining of a stomach virus last year, I was prescribed Dexilant. When I had the nausea symptoms recently, I took some of the leftovers. Those didn't do anything, but the diphenhydramine worked."

Maggie Lou (taken for less than 1 month) January 1, 2017

5 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"Anyone who takes this in order to take pain medication or if also taking any benzodiazepine, need to use caution since all of the three slow your heart rate and breathing down. Inexperienced users might fall asleep and pass away during fyi."

   
8.0

Big-Bryan July 25, 2016

5 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I had a couple surgeries on my jaw where I could not open it fully for an extended period of time. I am already semi-allergic to pain meds / anesthesia (excessive vomiting and nausea) so I was terrified to take my pain killers after surgery. The nurse / doctor recommended taking a couple Benadryl tablets (25mg) before the pain meds and it worked wonders! The only side effect is drowsiness."

   
10

MarD24 June 5, 2016

21 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I get severe migraines and was given this in the hospital instead of traditional nausea meds. It work well and I now use it at home and actually works better than Zofran or Phenagren."

   
10

Mmwillis December 29, 2015

47 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I got a severe back injury about 2 years ago. Couldn't function pain was so bad. So my doctor started putting me on codiene, then vicoden, then tramadol, and then so on but they all gave me hours of vomiting, gut wrenching cramps, and sweating. Read about benadryl being used to prevent this side effect. I took 3 25 mg tabs. I know that is one over recommended but I was desperate. 35 mins later I was sitting with my kids and not the trash can for the first time in a while. I can't believe I didn't figure this out sooner especially with a biotech degree."

   
10

A biotechnologist. (taken for less than 1 month) December 20, 2015

41 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I have Cyclic Vomiting Syndrome and take Benadryl everyday. It helps take the edge off. There are less side effects than other anti nausea medications and is safest for the body."

   
9.0

Andy D November 24, 2015

38 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"I tried everything yesterday to stop throwing up acid. I went from Nexium to Zantac to pepto to tums, nothing helped and it all just came back up an hour later. Thankfully my brother is a paramedic and told me about how they use benedryl for their nausea patients so I took 3 of the 25mg tablets and it worked!!"

   
10

Morgan Denee November 15, 2015

16 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I use it for nausea. It works wonders for me."

   
10

works! (taken for 10 years or more) October 2, 2015

50 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "Great for nausea. However does cause sleepiness."

   
9.0

cd101617 (taken for 1 to 6 months) November 30, 2014

57 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "I have emtophobia, that is, a pervasive fear of vomiting. I do not know if this affects vomiting, but if I feel nauseous, Benadryl works wonders. My stomach settles right down and my anxiety lowers just enough for me to deal with it without the use of benzodiazepines."

   
7.0

Anonymous June 15, 2012

95 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Benadryl (diphenhydramine): "Didn't seem to work very well for me."

   
2.0

Anonymous April 12, 2012

13 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

"I had a severe migraine, was driven to the hospital when regular pain relievers did not work. I was given IV Benadryl along with an anti-nausea medicine and fluids. I felt sleepy almost immediately, and my pain was lessened. The huge down side was that I felt a huge amount of anxiety for 48 hours afterward. I do not suffer from anxiety normally. I believe this was an adverse reaction of the Benadryl. "

   
4.0

Anonymous March 6, 2010

6 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Hide