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Dexedrine and Irritability: What Users Say

Irritability: mentioned by 5 users (4.1%)

Based on user experiences from 123 Dexedrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 18.7%
insomnia 7.3%
tiredness 4.9%
dry mouth 4.1%
irritability 4.1%
headaches 3.3%
memory loss 3.3%
brain fog 2.4%
depression 2.4%
fatigue 2.4%

Reviews for Dexedrine

Commonly mentioned side effects
  • Ham...
  • Taken for 2 to 5 years
  • October 6, 2016

For ADHD "Have been taking Dexedrine spansules (10 mg) for over 2 years, three times per day. I never knew I had rank ADHD all my life - problems with school, the law. I am 47 and have noticed my ambition for life has increased, having more energy. I used to be tired a lot, complaining, generally overall agitated. At the same time, I have many comorbidities to deal with but fortunately don't have to take any anxiety meds. Dexedrine is all I know, and I am satisfied with the results."

10 / 10
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91 Report
  • Rev...
  • Taken for 10 years or more
  • March 10, 2015

For ADHD "I wouldn't use any other type of ADHD medication! Adderall & many of the newer ADHD medications cause agitation & symptoms that make my condition worse. If I didn't use Dexedrine, I wouldn't take medication to treat my ADHD! More people need to educate themselves on how to treat ADHD."

9 / 10
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96 Report
  • Mrs...
  • Taken for less than 1 month
  • September 5, 2015

For ADHD "I am 39 years old and have been suffering from ADD my whole life. It wasn't until recently that I finally figured out what it was. After trying Ritalin, which didn't agree with me, and Adderall XR, which made me irritable, anti-social, and too engaged, I read the reviews of this and decided to give it a whirl. I'm only on week 1, but compared to the others, I am MUCH more myself with no anxiety! Also, I am shocked at how low of a dose gets the job done. I am on 5 mg once daily around noon. You may think you need more, but start low and see how much changes right before your very eyes. You get plenty done and still wind down after 4 hours. I sleep great, and my appetite is only affected the first 3 hours. I didn't give it a 10 because of some memory issues."

9 / 10
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44 Report

Frequently asked questions

  • Lco...
  • Taken for 1 to 6 months
  • March 25, 2016

For ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."

5 / 10
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15 Report
  • Lco...
  • Taken for 1 to 6 months
  • March 25, 2016

For ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."

5 / 10
Was this helpful?YesNo
15 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.