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Dexedrine and Dry Mouth: What Users Say

Dry mouth: mentioned by 5 users (4.1%)

Based on user experiences from 123 Dexedrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 18.7%
insomnia 7.3%
tiredness 4.9%
dry mouth 4.1%
irritability 4.1%
headaches 3.3%
memory loss 3.3%
brain fog 2.4%
depression 2.4%
fatigue 2.4%

Reviews for Dexedrine

Commonly mentioned side effects
  • Gin...
  • February 2, 2020

For Narcolepsy "I was diagnosed with narcolepsy at the age of eight. I was taking a 5 mg tablet that handled my situation. I was able to be an outgoing, loving child. My body was managing medication without falling asleep at inappropriate times. I am now over 70, now taking 15 mg span one twice a day. I am able to function and maintain a high-profile professional position. The very worst part of this medication is the price. My parents were paying $5.00 for my medication. After marriage, I was paying a $15 co-pay, then went to a $35 co-pay, and now it’s $144. I think this is totally unfair and a ridiculous charge for this drug. However, I don’t have a choice because it works. I have taken other medications that caused hallucinations, inability to drive, heart palpitations, and feeling like I was on a high all the time, however, Dexedrine does not create a problem, not in the slightest. I do not experience dry mouth, jitters, hallucinations, heart palpitations, or any side effects with Dexedrine."

10 / 10
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47 Report
  • Wol...
  • Taken for 5 to 10 years
  • July 27, 2014

For ADHD "This worked from the very second I started on it 5 years ago; Helped me focus like never before, although being someone with OCD who noticed most things anyway, this magnified it 10-fold. Gave a reserve of energy that helped even when tired. Only side effects were that you build up a tolerance rather quickly when it comes to the original effect, I began to grind my teeth as I slept, and had the worst dry mouth ever...could drink a gallon of water in 2 minutes and still have the driest mouth ever. Would recommend."

9 / 10
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81 Report
  • ele...
  • Taken for 10 years or more
  • August 14, 2015

For Narcolepsy "I've been taking Dexedrine spansules 15 mg, 2 pills at a time, 2-3 times a day for about 30 years for narcolepsy. I'm currently 57 years old. If it weren't for this Rx, I would probably never leave my house. Through the years, I have tried various alternative meds only to find they don't work as well. Among the alternatives tried are Adderall (made me actually violent); Provigil (absolutely ineffective); and Nuvigil was worse than ineffective...because it gave me the sensation of being high. So I thought it was working and I got behind the wheel of a car...bad idea. Changed back ASAP. Been on the same dosage for 20 years. Side effects: for 10 minutes every day, I get a bad dry mouth and feel anxious. Cost is prohibitive."

10 / 10
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64 Report

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Frequently asked questions

  • Sle...
  • Taken for 2 to 5 years
  • December 5, 2014

For Narcolepsy "Along with narcolepsy, I've also been diagnosed with ADHD. I have been taking Dexedrine for the last 4 years. At first, it was 5 mg tablets, which worked for a couple of months. As soon as my dose was increased to 10 mg spansules a day, my life has been so much easier since then. I can actually concentrate on one thing without wanting to quit in the middle and take a nap. Many side effects, including dry mouth almost every day, heart pounding, loss of appetite leading to weight loss, muscles twitching, and severe tiredness if I suddenly stop taking it."

8 / 10
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  • Tre...
  • Taken for 1 to 6 months
  • May 6, 2022

For ADHD "It sort of worked for me. I have been using Dexedrine 20 mg, prescribed in two 10 mg pills. Before that, 15 mg, one pill. Before that, one 10 mg pill. A problem I've had is with how my body metabolizes it. Rather than a smooth and consistent maintenance of focus, I experience peaks and valleys of it. It takes effect after 45 min, then it lasts for about 1-2 hours before I get incredibly sleepy for 1-2 hours, then it takes effect again, then I get sleepy again, then it takes effect again. I've talked with my psyche, and with the 20 mg split I take the first dose, then the second 10 mg dose 45 minutes later, and this has mostly, but not completely, solved the issue. Also, (consistent with all of the stimulant medications I've tried, though) is that it stops having any effect after about 3-4 days of usage straight. So I need to calculate for a day or two where I can't take the medication in order to allow for it to work later. Side effects: dry mouth, less hunger, nervousness."

6 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.