Denosumab and Pain: What Users Say (Page 5)

• Gay...
• Taken for 2 to 5 years
• September 8, 2024

For Osteoporosis "I was on this medication for 12 months to 2 years. I'm now having numbness in my hands and weakness in my legs. Cannot walk properly. I don't know why my doctor stopped the injection. I'm going to ask him. Pain in shoulders now, having cortisone injections. Not sure if this was included. I'm 73 years."

• You...
• Taken for 1 to 2 years
• February 1, 2019

For Osteoporosis "I'm a 44-year-old male with osteoporosis and now due for my fourth injection next month. I seriously don't want this garbage anymore. I'm sick and tired of aches and pains. I've been taking tramadol for pain relief that helped for a while, but now it's not working anymore. I'm not sure what to do anymore."

• Nan...
• Taken for 1 to 6 months
• November 9, 2017

For Osteoporosis "I wish that I had never heard of this medication. I have been on it for about 6 months now, and it has destroyed me and my family's life. I can't do anything that I was doing before I started this. I was very happy, active, loved to work, and really enjoyed playing with my grandchildren and taking vacations with all of my family. I don't know what I would have done if it had not been for my wonderful husband of 52 years. I have so much pain all over my entire body, and I feel so miserable all the time. My husband has had to take over the house cleaning, cooking, and shopping. It is also impossible to sleep because of pain in both hips and back. I am also losing a lot of my hair now. Prolia has taken the prize for being the worst medication ever."

• gui...
• Taken for 6 months to 1 year
• January 11, 2019

For Osteoporosis "Since I cannot take Fosamax and was so severe even after Forteo. I was told Prolia was the answer. I already suffer from autoimmune issues, which I was given shots to reduce pain in my back, only to find my lower discs are osteoporotic, and my knees and hips have lost bone density. I opted for Prolia. The first shot seemed to have no pain, after the second shot, loss of hair, pains throughout my body. Muscles knot up in shoulder and neck pain, toes hurt, legs and ankles swell. A rash lasted two months. I don't know how much longer I can go on without a bone-building medication. I was turned down for Tlymos because I took Forteo. My insurance company isn't worried about me being sick, or they would have approved Tlymos, a bone-building substance, and forgotten about the fact I took a bone builder. So far, that is what I have left to take, but even the insurance turned me away."

• gui...
• Taken for 6 months to 1 year
• January 11, 2019

For Osteoporosis "Since I cannot take Fosamax and was so severe even after Forteo. I was told Prolia was the answer. I already suffer from autoimmune issues, which I was given shots to reduce pain in my back, only to find my lower discs are osteoporotic, and my knees and hips have lost bone density. I opted for Prolia. The first shot seemed to have no pain, after the second shot, loss of hair, pains throughout my body. Muscles knot up in shoulder and neck pain, toes hurt, legs and ankles swell. A rash lasted two months. I don't know how much longer I can go on without a bone-building medication. I was turned down for Tlymos because I took Forteo. My insurance company isn't worried about me being sick, or they would have approved Tlymos, a bone-building substance, and forgotten about the fact I took a bone builder. So far, that is what I have left to take, but even the insurance turned me away."

• Kiy...
• Taken for less than 1 month
• June 6, 2018

For Osteoporosis "I had Prolia injection two weeks ago for the first time and developed bad gum pain and body ache. I want to stop taking it, however, if I do stop, I will have a side effect as well. They trap us both ways. Why do doctors recommend this horrible medication? I feel I am a victim of medical professionals and the pharmaceutical company that produces this medication."

• Gal...
• Taken for 5 to 10 years
• November 22, 2022

For Osteoporosis "Prolia is rebranded Fosamax, which ruined my mother's quality of life and caused her much pain and suffering when her femur snapped in two while she was making dinner. Her specialist told her that the product simply kept dead bone tissue from sloughing off as it normally would. That makes the bone look denser, but it is dead tissue, not the living tissue of healthy bones. And that when the bone breaks, it shatters into small pieces instead of a clean break. My mother never walked normally again. And our class action lawsuit was unsuccessful because the judge said, 'the warnings were not adequate enough to render a positive decision.'"

• Gal...
• Taken for 5 to 10 years
• November 22, 2022

For Osteoporosis "Prolia is rebranded Fosamax, which ruined my mother's quality of life and caused her much pain and suffering when her femur snapped in two while she was making dinner. Her specialist told her that the product simply kept dead bone tissue from sloughing off as it normally would. That makes the bone look denser, but it is dead tissue, not the living tissue of healthy bones. And that when the bone breaks, it shatters into small pieces instead of a clean break. My mother never walked normally again. And our class action lawsuit was unsuccessful because the judge said, 'the warnings were not adequate enough to render a positive decision.'"

• Ms ...
• Taken for 1 to 6 months
• April 17, 2018

For Osteoporosis "I am 58 years old, an avid exerciser, walker, and healthy eater. I have solid hips, arms, and legs, but due to Hashimoto's disease, came down with osteo in my spine. My doctors recommended Prolia. Amgen does provide a $1,500 credit to persons who have insurance, so this helped with the cost as my insurance only covered $400. HOWEVER, I know these drugs will not be effective after 5 years and carry many health risks. For myself, within 2 months after my first injection, I gained 20 pounds, my skin is dry, back pain, arm and upper leg pain, not one solid stool, UTIs, cough, and who knows what else. I have decided not to continue with this or any other of its kind. I'll stick with regular exercise, vitamin D and calcium supplements, and a healthy dietary intake. I think the risks of these drugs outweigh the benefits."

• Lyn...
• September 14, 2022

For Osteoporosis "After breast cancer and taking anastrozole for two years, I had a bone scan which showed thinning in my hips. I suffered some leg pain from that medication, but after adding Prolia, the pain is almost unbearable. I also suffer from CKD, which I’ve had all my life. Because of the kidney disease, I am unable to take calcium, pain meds, and anti-inflammatory drugs. I have been on Prolia for two years, and I will not take it anymore. I have constant pain in my ankles, knees, and hips. My doctor is also suggesting that I come off it for a while. Sorry, but I cannot recommend this drug. My last injection was almost six months ago, and the pain is still as bad as ever. I am praying it eventually goes away and I regain my strength."

• S-L...
• Taken for 6 months to 1 year
• November 17, 2022

For Osteoporosis "Pain in almost all of my joints. Have had 3 injections at 6-month intervals. The more exercise I do, the more pain I have. I have to use pain medication, especially to fall asleep. Beware of this medication."

• Not...
• Taken for 1 to 6 months
• February 8, 2018

For Osteoporosis "Whew! Had the injection 3 months ago and haven’t been the same since! Excruciating pain in both knees and one shoulder! My knees hurt all night long. In the morning, my knee joints are so stiff I can hardly walk. I cannot get up or down off the floor, can no longer kneel without pain! I was healthy and would walk several miles a day! Now it hurts to walk to the car! I too wish I had done more reading about this drug before taking it! Nervous to stop it, but more nervous to ever feel like this again! Anyone hear anything about a class action suit?"

• Gem...
• Taken for 5 to 10 years
• May 28, 2018

For Osteoporosis "My mom was given Prolia in injection form approximately six years ago, and overall her bone density improved. Over these years, she has had extreme insomnia and pain in her back, neck, wrists, fingers, legs, toes, and now recently her hip. She had an X-ray, and they found that her upper femur had a partial break. It just broke, no fall, and the area it broke was weak, but the rest of her femur was strong. She immediately had surgery, and they put a metal nail in to stabilize. Doctors are convinced that it was the extended use of Prolia. Now they want her on Forteo. Reading the side effects from that is horrifying, and it is a 2-year medicine, after that, they say Prolia again... Which is NOT going to happen. My advice, try diet and exercise first, and if on Prolia, only use it for a limited time."

• PAM...
• Taken for 1 to 2 years
• May 29, 2018

For Osteoporosis "After the 2nd and 3rd (the 3rd being my last), my life is a living hell. I have digestive issues, tons of mucus in stools, lots of severe pain in abdomen, both hips, both thighs, arms, cold sweats, jaw bone pain, and I feel weak, dizzy, and no appetite. It feels like I am dying. Don't take this prescription, it is very, very dangerous!!"

• PAM...
• Taken for 1 to 2 years
• May 29, 2018

For Osteoporosis "After the 2nd and 3rd (the 3rd being my last), my life is a living hell. I have digestive issues, tons of mucus in stools, lots of severe pain in abdomen, both hips, both thighs, arms, cold sweats, jaw bone pain, and I feel weak, dizzy, and no appetite. It feels like I am dying. Don't take this prescription, it is very, very dangerous!!"

• PAM...
• Taken for 1 to 2 years
• May 29, 2018

For Osteoporosis "After the 2nd and 3rd (the 3rd being my last), my life is a living hell. I have digestive issues, tons of mucus in stools, lots of severe pain in abdomen, both hips, both thighs, arms, cold sweats, jaw bone pain, and I feel weak, dizzy, and no appetite. It feels like I am dying. Don't take this prescription, it is very, very dangerous!!"

• Anonymous
• Taken for 1 to 2 years
• November 1, 2022

For Osteoporosis "I have had three doses of Prolia. Initially, I was skeptical, but the nurse assured me that she gave lots of these injections to patients and sure most people were okay. She then went on to say, sure, the common pain medications gave side effects, so you will be fine. I realize she thought she had my best interests at heart. But with hindsight, she probably didn't know the full extent of this very dangerous drug, as I sure doctors also are not well informed either. After the second injection, I had really bad headaches. Since the third one, my neck, shoulders, and arms are very painful. My hands and arms have muscle weakness. Despite the fear of stopping it and breaking bones, I won't get another injection. Shame on this pharma company for ruining so many lives worldwide."

• gra...
• Taken for 6 months to 1 year
• October 3, 2017

For Osteoporosis "Prolia is killing me, too. My leg and buttocks are in constant pain that just doesn't stop. It's hard to lay down, it's hard to stand up, it's hard to just sit here without shifting position every three seconds. Here's the thing with stopping Prolia before finishing the drug. You are apt to have vertebrae break spontaneously. Which is worse? A broken back or pain that is almost unbearable? We should have been informed about these side effects. I bet Blythe Danner never even really took the shot or she wouldn't be happy up there on stage. Point is, don't stop till it's done. You could be sorry."

• Hol...
• December 30, 2016

For Osteoporosis "I have been on Prolia for 2.5 years. Just this last one, I have noticed more pain in my arm. Going on 2 weeks. Other than that, I have had no problem prior. I will continue taking it as long as I can afford it."

• Can...
• Taken for less than 1 month
• June 28, 2018

For Osteoporosis "The first shot of Prolia I had, I asked the doctor to break it up into 2 sessions a month apart from each other. Then I had no side effects. The second shot I thought would be fine full force, but BIG mistake! Now I have a terrible sinus infection (apparently a common side effect for women 60+) and gum pain. This all happened within a few days of the injection. Hoping things improve this second week. I'm not going to take Prolia again."

• Joa...
• May 3, 2021

For Osteoporosis "After a severely painful experience with a Reclast infusion (which are once per year), I was put on Prolia injections every six months. After a yearly infusion of Reclast and two 6-month intervals of Prolia, I have pain in my joints, muscles, groin, tendonitis in my Achilles tendons and thumb, headaches, nausea, confusion, weakness, fatigue, at least 40 pounds of weight gain, and severe back and hip pain. Before, I was on the go all the time, walking, exercising, and busy constantly, now I don't feel like doing anything because I never feel good and hurt all the time. Needless to say, I canceled my next injection and will take nothing for the osteoporosis. Even though I have a pretty good chance, even more so now, of having a fracture since I took the injections. Can you believe this? When you stop taking Prolia, you are more at risk than you were before you took it! Thanks to all the doctors that only think of how much money they can make off of someone instead of thinking of their health."

• Joa...
• May 3, 2021

For Osteoporosis "After a severely painful experience with a Reclast infusion (which are once per year), I was put on Prolia injections every six months. After a yearly infusion of Reclast and two 6-month intervals of Prolia, I have pain in my joints, muscles, groin, tendonitis in my Achilles tendons and thumb, headaches, nausea, confusion, weakness, fatigue, at least 40 pounds of weight gain, and severe back and hip pain. Before, I was on the go all the time, walking, exercising, and busy constantly, now I don't feel like doing anything because I never feel good and hurt all the time. Needless to say, I canceled my next injection and will take nothing for the osteoporosis. Even though I have a pretty good chance, even more so now, of having a fracture since I took the injections. Can you believe this? When you stop taking Prolia, you are more at risk than you were before you took it! Thanks to all the doctors that only think of how much money they can make off of someone instead of thinking of their health."

• AW ...
• December 17, 2016

For Hypercalcemia of Malignancy "I have lung cancer with mets to bone. Two hours after the injection, I experienced the worst pain ever in my life! I walked into the infusion area without any body pain, just a very slight backache which Advil was helping, and 2 hours later I was crippled. It's 2 weeks now, and I'm either in a wheelchair or walking around the house with a cane. Horrible, horrible medication. I now take oxycontin every 12 hours and oxycodone every 3 hours. Refuse this drug if you are smart. Even my oncologist is 'surprised' with the side effects I have. I refuse to have a second injection of Xgeva."

• mar...
• Taken for 6 months to 1 year
• April 4, 2018

For Osteoporosis "I received my first Prolia injection in June 2017 and the second injection on December 19, 2017. I did experience back, hip, and jaw pain with the first; however, it has been much worse after the second. I’m taking six Advil per day with little relief. The pain is interfering with activity at work, home, etc. I will have to talk to my nurse practitioner. My bone density has improved; however, due to the pain, I wish I had not taken the medication."

• mar...
• Taken for 6 months to 1 year
• April 4, 2018

For Osteoporosis "I received my first Prolia injection in June 2017 and the second injection on December 19, 2017. I did experience back, hip, and jaw pain with the first; however, it has been much worse after the second. I’m taking six Advil per day with little relief. The pain is interfering with activity at work, home, etc. I will have to talk to my nurse practitioner. My bone density has improved; however, due to the pain, I wish I had not taken the medication."