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Prolia User Reviews & Ratings (Page 5)

Prolia has an average rating of 2.9 out of 10 from a total of 375 reviews on Drugs.com. 16% of reviewers reported a positive experience, while 76% reported a negative experience.

Reviews for Prolia

Commonly mentioned side effects
  • Lui...
  • Taken for less than 1 month
  • September 15, 2020

For Osteoporosis "Prolia has given back pain so that it feels like it is going to break. Pains in my arms, legs, and hands."

2 / 10
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  • Joe...
  • September 27, 2018

For Osteoporosis "My last shot was May 23, 2015. I am still suffering with muscle and joint pain. Never had vertigo before taking seven shots. I have now fallen 4 times! I cannot say 100% that these were caused by Prolia, but I am 99% sure they were caused by the injections I took. My pains and side effects, sorry to say, have not gone away. I post this hopefully to help others about Prolia. I wish I had known in 2012 before ever taking this horrible drug!"

1 / 10
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  • Bac...
  • Taken for less than 1 month
  • July 12, 2019

For Osteoporosis "I found that after having one injection of Prolia, the side effects were worse than the possibility of maybe breaking a bone. I had muscle and joint pain, back pain, vertigo, hip pain, and just felt flu-ish for more than one month after the injection. I now have diarrhea. I will not be taking it again."

2 / 10
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Frequently asked questions

  • Mol...
  • Taken for 6 months to 1 year
  • November 14, 2019

For Osteoporosis "1st Prolia needle ok, 2nd needle within 2 weeks I got so many side effects of joint pain. Unbelievable arms, legs, even tips of shoulders were sore to touch. I am tired and can’t do what I want to do. My appetite is not good and I have lost weight. I should have looked into Prolia side effects. I would not wish this on anyone. My thoughts and prayers go out to anybody who is on this awful drug Prolia."

1 / 10
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  • j f...
  • October 8, 2016

For Osteoporosis "Had 3 shots: #1. The provider knew nothing other than she was supposed to administer the shot. #2. Did explain somewhat about the shot. #3. Did not know where on the arm for the injection. Should have not taken #3. Several days after each shot, sweated at night. The bone between knee and hip hurt tremendously for several days, had headaches. It has been 2 years since the last Prolia shot. Maybe things would have been different if all had started correctly. Explain, explain is important for administering any drugs to patients."

1 / 10
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  • Emm...
  • Taken for less than 1 month
  • March 1, 2020

For Osteoporosis "You are encouraged to report negative side effects of prescription drugs to the FDA. Google 'FDA Adverse Event Reporting System'."

1 / 10
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  • Ter...
  • January 28, 2017

For Osteoporosis "I love the twice a year shot. The company is awesome and very helpful. But... 1st shot no side effects, 2nd shot left groin pain for about a week, 3rd shot and now right-sided groin pain since October that goes to my thigh, hip, and pelvic bone. Pain is severe at times. Also, thyroid problem is worse (not sure if related) and right side lower back pain. I can no longer take the medication."

3 / 10
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More FAQ

  • Ree...
  • Taken for 1 to 6 months
  • November 5, 2019

For Osteoporosis "On my last visit to the cancer center, they put me on a new injection for osteoporosis (Prolia) and had to sign a form to take it. Like a lot of you, I trusted my doctors and took the shot back in September 2019. OMG, I was not ready for what I was in for with the side effects. I have no energy, my legs feel like they give out after 10 steps, making me take a break. My bones hurt all the time, which they did anyway with the hormone blocker, but this just intensified it. I have no appetite, can't sleep, and my memory is horrible. I have a very multitasking job, and it has been tough keeping up with everything. It feels like it's all about the almighty dollars with these doctors, and I will not take this drug again. One thing I have found concerning osteoporosis is there are classes called Osteo Strong that help build bone naturally in your body, and you attend once a week."

1 / 10
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  • Lac...
  • November 24, 2019

For Osteoporosis "I’m so sorry I ever took Prolia shots. After 4 injections, I am in constant terrible pain. I am 66 years old and was so healthy and mobile before the Prolia. Now, leg, hip, arm, and jaw pain. Barely walking now. Taking physical therapy but no relief. This drug should NOT be on the market!! Does anyone know if, after discontinuing the Prolia, this stuff ever leaves our bodies?"

2 / 10
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  • Jas...
  • Taken for 6 months to 1 year
  • June 12, 2019

For Osteoporosis "I was on Boniva for 10 years with no improvement in my bones. My doctor switched me to Prolia shots. I took my first shot of Prolia in January 2018 and developed severe mouth ulcers, sloughing of my gums. I could not handle spice or salt, and my nutrition fell. At that time, I did not associate it with Prolia. I took my second shot in August, and my mouth ulcers flared up. Severe ulcers in the gums, upper palate, back of the throat, and nasopharynx area. My mouth had grey, purple, and white patches. I was unable to eat. I also developed severe jaw pain, bone pain, and muscle weakness. For three days, my low back, hips, and legs froze, and I was in excruciating pain and could not walk. I was in bed with ice packs and anti-inflammatories. I was frightened. I have stopped Prolia. It has been more than a year, and my mouth ulcers have not healed. I am now being treated at a university hospital. This is not a safe medicine and should not be prescribed."

1 / 10
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  • MTC...
  • Taken for 1 to 6 months
  • August 12, 2017

For Osteoporosis "Received injection 02/20/2017. Upon the 3rd day, overall body hurt. On the 8th day, with no relief, I contacted the infusion center. They stated it was unusual. On the 12th day, they advised me to contact my primary care physician. I experienced severe thigh bone, muscle, and joint pain in my hips, legs, arms, and shoulders. This discomfort impeded my abilities to exercise. Prior to this injection, I would swim 3 times a week, do daily light weights, and yoga for exercise. I could not put any pressure on my knees if I attempted to kneel down because it felt like my thigh bone was going to break, as well as getting sharp pain in my groin area. To date, August 2017, still discomfort, however, not as severe. Refused 2nd injection. Do not recommend Prolia."

2 / 10
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  • Cat...
  • Taken for 2 to 5 years
  • April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."

1 / 10
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  • XGy...
  • Taken for 1 to 6 months
  • November 25, 2019

For Osteoporosis "This is now 1 year, 1 month from my one and only Prolia injection. Reading the other comments from patients who have had poor to terrible side effects, I am certain that one dose of Prolia likely still lingers in my system and the side effects continue. My bone and muscle pain kicked in with a vengeance and has not abated. Walking became and remains difficult due to body pain and loss of strength/balance/pain in addition to which, my skin rashes causing both pain and itching continue. I regret being talked into taking Prolia even though my osteoporosis remains seriously advanced. All of the side effects continue although I only had the first injection due to the severe reaction that kicked in within a few days. Note: Amgen is recently promoting a 'new' drug 'Evenity' ... an almost identical to Prolia... which has major warnings, actual black boxed warning - some even worse than the Prolia warnings. Doctors continue to advise trying the drug. For me, that is not an option."

1 / 10
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  • Sto...
  • Taken for 2 to 5 years
  • February 16, 2021

For Osteoporosis "Had my fifth shot of Prolia on December 8th, 2020. Will definitely not be taking this drug again. I found that with each passing injection, the symptoms became more severe. I have gone from being a very fit person to being totally disabled. Muscle weakness in thigh muscles and arms. Extreme pain in shoulders and arms. Very tight rib cage muscles. No energy. Extreme nausea. Discomfort in my throat. Dry cough at night. Muscle stiffness, twitching, cramps, and spasms. Severe right hip pain and sciatica pain. All of these started after taking Prolia."

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  • Luc...
  • Taken for 1 to 2 years
  • October 12, 2019

For Osteoporosis "My first 2 shots of Prolia were positive, and my T-score improved by 25% in my hips and back from -2.8. I took my 3rd shot in July 2019 and have been having increased pains ever since, from my hip folds all the way down to my toes, in my lumbar spine region, and in my ribs. I get severe headaches on and off and experience nausea (extremely flu-like) every day. The doctor never mentioned the side effects of Prolia, and I trusted him so much that I didn’t do any investigating before taking it. I also have what seems like a never-ending cold. Even nasal spray gives very little relief. I’ve been to my new GP doctor twice since my 3rd shot, but she has never seen a connection between my symptoms and Prolia. I put a message in MYCHART yesterday saying I am done with Prolia! It’s not worth being sick all the time."

2 / 10
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  • Tli...
  • Taken for 1 to 2 years
  • February 15, 2020

For Osteoporosis "I have osteoporosis. I just had my third injection on Feb. 14, 2020. Prolia is working great for me. I was having severe pain with walking and losing bone density. I now walk with no pain, and my bone density has increased. I have had no side effects other than a deep feeling in my bones for the first couple of days after the injection, which slightly aches. My quality of life has greatly increased. I highly recommend this for anyone with substantial bone loss and experiencing pain."

10 / 10
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  • mia...
  • Taken for 2 to 5 years
  • May 3, 2017

For Osteoporosis "After taking Fosamax for 5 years, I was prescribed Prolia in June 2013. I have been hospitalized on 4 occasions with back spasms so severe that it took over 2 hours to get me in the ambulance fully medicated. I then spent 8-10 days in the hospital each time, waiting for the spasms to stop. After being discharged each time, I had to use a walker for a week because I couldn't stand longer than a few steps due to the damage the spasms had caused. No doctor has been able to give me answers until 4 days ago, after spending another day in the hospital because I spent 2 hours on the floor in a shopping center, that Prolia is more than likely the reason. I also have ankles which are the size of the tops of my legs, this too has only been in the last 3 years."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • December 8, 2016

For Osteoporosis "My mom has been given Prolia twice, 6 months apart. Each time, she had a series of mini-strokes a week after the shots were administered. Her face and left arm would go numb, accompanied by nausea. The mini-strokes would last 1-2 minutes, and repeat 4-5 times a day. She was put on blood thinners after the first episodes. Any testing done did not reveal anything. Is this yet another side effect of Prolia? Has anyone else experienced this? She will not take this drug again!"

1 / 10
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  • lyn...
  • April 6, 2019

For Osteoporosis "I had an injection of Prolia on Feb. 13, 2019. My health at that time was perfect, and I was only taking vitamins for overall health. On the 20th day, my blood pressure was high while at a yearly visit to the doctor. On the 22nd day after the injection, I went to the ER for visual disturbances, high blood pressure, and was told that I was having an ocular migraine. My eye doctor later confirmed that. Before Prolia, I had not had a headache in over 10 years. On the 26th day, my heart began to race and would not stop. This lasted all night. On the 32nd and 33rd day after the injection, my heart raced for two days and two nights. I went to the doctor and was started on medicine for panic attacks. I had never had a panic attack before the shot. I feel terrible, and I don't even feel like myself. I will never take another injection of Prolia. I had excellent health prior to the shot, and now my energy level is so low I don't feel like doing anything."

2 / 10
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  • Slm...
  • January 1, 2020

For Osteoporosis "I had one injection in 2018 and started having side effects the next day. Skin rash and itching, then mouth ulcers, swollen lips and tongue. Pain in feet, legs, and hip, and fatigue. I would never recommend nor have this drug again. It has been over a year, and I still have symptoms."

1 / 10
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  • Fre...
  • Taken for 1 to 6 months
  • June 15, 2019

For Osteoporosis "I am 61 years old, in general excellent health. After menopause, I had issues with insomnia, headaches, lethargy, and a bad mood. As time went on, these symptoms abated. I also began Synthroid for low thyroid function and was feeling better than I had in years. Since taking Prolia one month ago, my headaches have returned, I feel fatigued, have constipation, and generally in a poor frame of mind. I am sure this medication is good for bone density, but these quality of life issues are not acceptable for me. Will not be taking it again."

2 / 10
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  • Sho...
  • Taken for 1 to 6 months
  • September 21, 2016

For Osteoporosis "58 years old. Had the Prolia injection for newly diagnosed osteoporosis 3 months ago. Experienced flu-like symptoms for 2 weeks; muscle aches, constant burping, loose stools, extreme fatigue in thigh muscles. The manufacturer side effects list included depression. I wouldn't classify it as that, but, I definitely felt very exasperated for a couple of weeks, and, just not my usual cheery self. Then it all went away. I have no symptoms now & I don't know if it's helped my disease or not."

5 / 10
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  • yog...
  • August 30, 2016

For Osteoporosis "The Prolia is helping with my bone density. I am allergic to Actonel, Boniva, Evista, etc. I have taken my third shot three weeks ago. I have experienced blisters between my toes, the bottom of my feet peeling off, a rash, small pinpoint red dots on my skin, a cough, stomach discomfort, bleeding sores on my face, and my cholesterol has gone up to the highest point of my life! I have also gained 10 pounds that are almost impossible to lose. I'll see what my cholesterol level is in another 6 months. I believe it should be down by then."

10 / 10
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  • Jes...
  • Taken for 1 to 6 months
  • April 28, 2016

For Osteoporosis "Terrible, have sciatica and severe leg pain in the other leg."

1 / 10
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  • Nom...
  • Taken for 1 to 6 months
  • September 7, 2019

For Osteoporosis "After one treatment, severe jaw and hip pain, rashes, and my hair has started falling out. I wasn't told by my doctor that I couldn't stop this medication without risking spinal fractures. This drug shouldn't be on the market. I only gave it a one because 0 wasn't an option."

1 / 10
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