Prolia and Pain: What Users Say (Page 3)

• Cat...
• Taken for 2 to 5 years
• April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."

• Cat...
• Taken for 2 to 5 years
• April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."

• Cat...
• Taken for 2 to 5 years
• April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."

• XGy...
• Taken for 1 to 6 months
• November 25, 2019

For Osteoporosis "This is now 1 year, 1 month from my one and only Prolia injection. Reading the other comments from patients who have had poor to terrible side effects, I am certain that one dose of Prolia likely still lingers in my system and the side effects continue. My bone and muscle pain kicked in with a vengeance and has not abated. Walking became and remains difficult due to body pain and loss of strength/balance/pain in addition to which, my skin rashes causing both pain and itching continue. I regret being talked into taking Prolia even though my osteoporosis remains seriously advanced. All of the side effects continue although I only had the first injection due to the severe reaction that kicked in within a few days. Note: Amgen is recently promoting a 'new' drug 'Evenity' ... an almost identical to Prolia... which has major warnings, actual black boxed warning - some even worse than the Prolia warnings. Doctors continue to advise trying the drug. For me, that is not an option."

• Sto...
• Taken for 2 to 5 years
• February 16, 2021

For Osteoporosis "Had my fifth shot of Prolia on December 8th, 2020. Will definitely not be taking this drug again. I found that with each passing injection, the symptoms became more severe. I have gone from being a very fit person to being totally disabled. Muscle weakness in thigh muscles and arms. Extreme pain in shoulders and arms. Very tight rib cage muscles. No energy. Extreme nausea. Discomfort in my throat. Dry cough at night. Muscle stiffness, twitching, cramps, and spasms. Severe right hip pain and sciatica pain. All of these started after taking Prolia."

• Slm...
• January 1, 2020

For Osteoporosis "I had one injection in 2018 and started having side effects the next day. Skin rash and itching, then mouth ulcers, swollen lips and tongue. Pain in feet, legs, and hip, and fatigue. I would never recommend nor have this drug again. It has been over a year, and I still have symptoms."

• Slm...
• January 1, 2020

For Osteoporosis "I had one injection in 2018 and started having side effects the next day. Skin rash and itching, then mouth ulcers, swollen lips and tongue. Pain in feet, legs, and hip, and fatigue. I would never recommend nor have this drug again. It has been over a year, and I still have symptoms."

• Slm...
• January 1, 2020

For Osteoporosis "I had one injection in 2018 and started having side effects the next day. Skin rash and itching, then mouth ulcers, swollen lips and tongue. Pain in feet, legs, and hip, and fatigue. I would never recommend nor have this drug again. It has been over a year, and I still have symptoms."

• Jes...
• Taken for 1 to 6 months
• April 28, 2016

For Osteoporosis "Terrible, have sciatica and severe leg pain in the other leg."

• Nom...
• Taken for 1 to 6 months
• September 7, 2019

For Osteoporosis "After one treatment, severe jaw and hip pain, rashes, and my hair has started falling out. I wasn't told by my doctor that I couldn't stop this medication without risking spinal fractures. This drug shouldn't be on the market. I only gave it a one because 0 wasn't an option."

• Dag...
• Taken for 6 months to 1 year
• June 6, 2019

For Osteoporosis "In May 2018, I had my 1st Prolia injection for mild bone loss. After that, I just had occasional hip pain. Two weeks after my 2nd injection in November 2018, my doctor sent me for physical therapy because of severe lower back pain. The pain moved from the lower back to my thighs. I received a steroid shot into my lower spine without relief. 2 months ago, I underwent arthroscopic spine surgery to clean up discs and remove a bone spur. While my back healed, the back and leg pains persisted. Walking, especially stairs, has become challenging, where I used to walk 3 miles daily, I can now barely walk around the block. My left leg has weakened. Back to physical therapy. According to my surgeon, I should be able to do routine housework, yard work, walking, and other low-level activities without pain. I truly hope that with time, Advil, and a positive outlook, the severity of the pain will lessen, and I can enjoy life again. One thing I know for sure: I will not be getting another injection of Prolia."

• Dag...
• Taken for 6 months to 1 year
• June 6, 2019

For Osteoporosis "In May 2018, I had my 1st Prolia injection for mild bone loss. After that, I just had occasional hip pain. Two weeks after my 2nd injection in November 2018, my doctor sent me for physical therapy because of severe lower back pain. The pain moved from the lower back to my thighs. I received a steroid shot into my lower spine without relief. 2 months ago, I underwent arthroscopic spine surgery to clean up discs and remove a bone spur. While my back healed, the back and leg pains persisted. Walking, especially stairs, has become challenging, where I used to walk 3 miles daily, I can now barely walk around the block. My left leg has weakened. Back to physical therapy. According to my surgeon, I should be able to do routine housework, yard work, walking, and other low-level activities without pain. I truly hope that with time, Advil, and a positive outlook, the severity of the pain will lessen, and I can enjoy life again. One thing I know for sure: I will not be getting another injection of Prolia."

• sal...
• Taken for 1 to 6 months
• September 22, 2018

For Osteoporosis "Received my second shot of Prolia one month ago. Within a week, I experienced thigh pain during the night. Pain has increased to the point of making it difficult to bend my leg during the night without experiencing terrible pain from my knee to groin area. Once on my feet, pain lessens but is a constant. Woke this morning to the same pain, but also pain in my upper arms and back as well. When I called my doctor - as suggested in the brochure - his response was to make an appointment with an orthopedist as it did not likely have anything to do with the medication. I am a healthy active woman who walks daily and maintains my own home. Don't know what is more frustrating - the pain or his response! After reading the comments by others, my symptoms are not unique. I will most likely discontinue this medication. Should also add, I am not taking any other medication."

• sal...
• Taken for 1 to 6 months
• September 22, 2018

For Osteoporosis "Received my second shot of Prolia one month ago. Within a week, I experienced thigh pain during the night. Pain has increased to the point of making it difficult to bend my leg during the night without experiencing terrible pain from my knee to groin area. Once on my feet, pain lessens but is a constant. Woke this morning to the same pain, but also pain in my upper arms and back as well. When I called my doctor - as suggested in the brochure - his response was to make an appointment with an orthopedist as it did not likely have anything to do with the medication. I am a healthy active woman who walks daily and maintains my own home. Don't know what is more frustrating - the pain or his response! After reading the comments by others, my symptoms are not unique. I will most likely discontinue this medication. Should also add, I am not taking any other medication."

• Bre...
• Taken for 6 months to 1 year
• January 2, 2021

For Osteoporosis "Had a wedge compression fracture in August 2019, doctor ordered Prolia injection. Wish I had never had it, developed stomach and intestinal problems, reflux (never had any problems with that before), pain in groin (a cyst on ovary was found), increased pain in neck, had an increase in blood pressure, pulse rate increased, pain in arms, legs, and continue with pain in back, muscle soreness, and weakness. Was diagnosed with Barrett's Esophagus in January 2020. Never will allow another injection, and of course, doctors don't believe it caused these problems."

• Bre...
• Taken for 6 months to 1 year
• January 2, 2021

For Osteoporosis "Had a wedge compression fracture in August 2019, doctor ordered Prolia injection. Wish I had never had it, developed stomach and intestinal problems, reflux (never had any problems with that before), pain in groin (a cyst on ovary was found), increased pain in neck, had an increase in blood pressure, pulse rate increased, pain in arms, legs, and continue with pain in back, muscle soreness, and weakness. Was diagnosed with Barrett's Esophagus in January 2020. Never will allow another injection, and of course, doctors don't believe it caused these problems."

• Tri...
• Taken for 6 months to 1 year
• September 23, 2019

For Osteoporosis "I had my 2nd Prolia injection two months ago, the second stage of a two-year research study. Five days ago I woke up with the worst pain of my life, starting in my hip and extending down my leg. Until now, I have been a very active 66-year-old, with absolutely no health problems. Oh, how I wish I had never signed on to the study. The osteoporosis that made me eligible to participate was minimal; this pain is atrocious. I trusted the doctor heading the research to, first of all, do no harm. She apparently did not deserve that trust. She did not warn me that I could suffer serious debilitation as a result of Prolia, even after I spoke of a new, nagging hip pain that started after the first injection."

• Esv...
• Taken for 1 to 6 months
• June 10, 2017

For Osteoporosis "Had mild hip pain before, but after the Prolia injection it increased to a full-blown 10 in pain :( Feels like my bones actually have gotten weaker while on this medication."

• Esv...
• Taken for 1 to 6 months
• June 10, 2017

For Osteoporosis "Had mild hip pain before, but after the Prolia injection it increased to a full-blown 10 in pain :( Feels like my bones actually have gotten weaker while on this medication."

• mus...
• Taken for 5 to 10 years
• October 5, 2019

For Osteoporosis "I was diagnosed with fibro (Epstein Barr) 20+ years ago, so a lot of the side effects from Prolia, I blamed on that. I have been getting more severe pain (shoulder, arm, wrist, fingers, femur, knees, feet, etc. - you get the picture). I was in so much pain before the last injection, but was warned about the consequences by the PCP and Endro docs, waited an extra month and felt great so went ahead and had another injection of Prolia. I am 4 months in on that and in so much pain I can hardly function. The docs all act like it is worth taking. Boy, they must be getting a bundle from big Pharma!! #NOMOREPROLIA"

• san...
• Taken for 1 to 6 months
• September 11, 2018

For Osteoporosis "I was fine on July 5, 2018, at my RA doctor's check. I had no pain. I got the Prolia shot and was in excruciating pain at a level 10 in less than 12 hours. It has been 2 months, and I am still experiencing severe effects. I haven't been the same since. I called the doctor 4 times, went in, and received two steroid shots in my shoulders, but they are denying it could be from the Prolia shot."

• Mar...
• Taken for 6 months to 1 year
• August 10, 2017

For Osteoporosis "I had my first Prolia injection in November 2016. Within a few weeks, I gained 10 lbs very rapidly, but I put it down to changing the time of taking Prednisolone meds that I am on long-term for Polymyalgia. I had the 2nd injection in May 2017, and I can only say that since then, I feel like I've been run over by a bus! I experienced bad insomnia, fatigue, neck pain, pain in upper legs, and upper arms. I also had numbness in my face, which is very annoying, especially near my eye, as it feels like something is too close to my eye! I will not take this drug again and am mad at myself that I did not check out the side effects beforehand. I took the word of my consultant that it was the greatest thing!"

• Anonymous
• August 24, 2023

For Osteoporosis "Had my second shot July 13, 2023, then on July 27, I broke my rib. I’ve never broken a bone in my whole entire life. I am 67 years old now, my whole body is aching. My fingers hurt, my wrist and arms hurt. My jaw hurts. My back is in tremendous pain constantly. I feel like my whole bones are breaking inside. Can’t sleep. I won’t take this again. It really saddens me that they give this to people."

• val...
• October 7, 2018

For Osteoporosis "My wife has very severe Prolia side effects, including at least one atypical femur fracture that is not healed despite two surgeries at UCSF within two years. She walks with a walker. 'At least' refers to the fact that she has multiple sources of pain that may be related to other bones affected by Prolia (Amgen). In June 2015, the doctor advised her that she has an elevated fracture risk and proposed to start using Prolia. He did not discuss with her the possible serious side effects, in particular, the so-called 'atypical' fracture. After the first two shots, my wife developed pain in the leg that after some time became pain and limping. At no time did the doctors consider the possibility of a Prolia side effect. She continued Prolia shots for another year (two shots). After the last shot and many doctor visits, a doctor at UCSF diagnosed the problem as an atypical fracture of the femur due to Prolia."

• Ste...
• Taken for 1 to 2 years
• June 15, 2019

For Osteoporosis "I’m on my third round of Prolia. First round, I had no side effects. Second round, pain in hips and jaw on both sides of hip and jaw. Spoke to a nurse and was told they did not have any negative feedback to date. Third round, hip pain is present and now bone pain in left arm. The bone pain in all three locations is aching bone pain. It gets your attention. I’m just turning 50, not overweight, have osteoporosis on a low level. I’m now deciding I need to find an alternative. It is difficult to determine what is the Prolia side effects and other aspects of aging and some fibromyalgia that I have but I do feel, after reading other's experience, Prolia is causing further pain that was nonexistent prior to the shots."