Prolia and Pain: What Users Say (Page 2)

• Anonymous
• November 14, 2015

For Osteoporosis "I had a shot 3 months ago and have pain in my leg, shoulder, toes, and fingers. I have flu-like symptoms off and on. This is a horrible drug, and I will not be taking it again."

• sha...
• March 11, 2017

For Osteoporosis "My mom got this shot a month ago and her life has been hell. Extreme pain that she ended up in the hospital getting injections for pain and on morphine. Extreme headaches to where she cannot function, along with godawful headaches. Jaw pain, muscle cramps, fevers, stomach issues, bladder issues, short-term memory issues, and with all this happening she is now depressed from all the issues which now gives her anxiety wondering if these will go away or not. The sad thing is that not all the symptoms show up right after the shot. They show up weeks later and no one can tell you how long they will last."

• sha...
• March 11, 2017

For Osteoporosis "My mom got this shot a month ago and her life has been hell. Extreme pain that she ended up in the hospital getting injections for pain and on morphine. Extreme headaches to where she cannot function, along with godawful headaches. Jaw pain, muscle cramps, fevers, stomach issues, bladder issues, short-term memory issues, and with all this happening she is now depressed from all the issues which now gives her anxiety wondering if these will go away or not. The sad thing is that not all the symptoms show up right after the shot. They show up weeks later and no one can tell you how long they will last."

• Lak...
• Taken for 1 to 2 years
• July 10, 2016

For Osteoporosis "Various side effects including fractures in both feet and bad pain and aching in right leg making it almost impossible to walk and keeping me awake and in pain. It is time for my third Prolia shot and I have suffered from this for two months and am no better. This has not been a positive experience but a bad and painful one leaving me unable to get out and perform any daily tasks or functions."

• Jud...
• June 13, 2016

For Osteoporosis "I am having severe jaw pain, almost unbearable. It is one of the most horrible experiences I have ever gone through. Will not take this drug again. What is strange is that I didn't have a problem until after the second shot. Since then have not only teeth pain but sick with sore throat and cold. Also bad digestive problems."

• Mar...
• Taken for 1 to 6 months
• May 26, 2016

For Osteoporosis "From the start, I began to experience side effects. The most bothersome are the extreme sweating episodes followed by chills at least 12 times a day or more. In addition, other side effects are more pain in my lower back and hips as well as a rash with associated itch on my upper back. I will never get another Prolia shot!!! Wish I knew there would be so much discomfort!"

• Cyd...
• Taken for 1 to 6 months
• January 16, 2020

For Osteoporosis "I had my first Prolia injection in October and will never have another one! I now live with constant jaw pain, joint pain, and chronic fatigue. I’ve had to cut out many activities because I feel horrible and can barely get through my exercise class... my oncologist recommended I start on a bone strengthener in case my breast cancer spread. However, I have no evidence of cancer in my breast or anywhere at this point and refuse to feel this bad from a medication. Ladies, do your research before you follow everything your health care provider suggests!"

• Til...
• May 30, 2017

For Osteoporosis "Three days after receiving my first Prolia injection, I developed a cough which turned into bronchitis and was treated with antibiotics - bad luck, a coincidence I thought. A month later, my life changed with severe bone pain in my right jaw. I had lockjaw five times. Pain in my right shoulder, ribs, and my neck was so stiff, but worse was my lack of mobility. My morning walk to the bathroom was just like watching Frankenstein walk, I couldn't move any faster because of the pain. Getting on and off the toilet was a major event. Turning in bed was excruciating and sometimes impossible. This lasted the whole summer of 2015, which eventually tapered off to where I am today. Worst experience of my life. No more Prolia for me."

• G10...
• July 20, 2016

For Osteoporosis "1 shot, due another in August and wondering. Constipation very severe, fatigue, hip pain, upper arm pain and shooting pains in head. I do not know if there are other options available and scared to take second shot in case things get worse."

• LSt...
• Taken for 2 to 5 years
• April 4, 2017

For Osteoporosis "I was diagnosed with osteo in 2010 and was put on Fosamax, along with a daily dose of calcium-VitD tablet. In 2014, the doctor changed my prescription to Prolia due to its stronger potency, along with the continued Cal-VitD tablet. Though my bone density increased 10% since taking Prolia, I feel the side effects may outweigh any positive bone density increases. With constant jaw pain, I also have unusual problems with my teeth: constant infections, pain in one tooth or another, and root canal treatments needed. I suffer from insomnia, something I never had pre-Prolia. With no warning or trigger, I have constant blood blisters in my mouth, some as big as 5 cent pieces. My cholesterol has increased. I feel unusually tired and have regular leg cramps."

• Ver...
• Taken for 1 to 6 months
• January 20, 2020

For Osteoporosis "My GP recommended I have the Prolia injection for my bone density. I read about the side effects but hadn’t seen this website, so went ahead on 5 Nov 2019. Within 24 hours, I experienced terrible pain in my left arm. The pain was in the bone. This occurred two days running before it subsided. I saw my GP two days later and told her of the pain and I said never again will I have this injection. She agreed. The pain went away but other symptoms attacked me. Extreme irritability, lethargy, bloating, loss of appetite. I visited my GP twice about the side effects. The second time (10 days ago), she recommended a strong probiotic. I took it and in two days the bloating had gone and my appetite began to return. The Prolia drug had attacked the good bacteria in my gut. After 10 days on the probiotic, I feel normal again. Three months and two weeks later, and it is out of my system."

• Sus...
• Taken for 6 months to 1 year
• June 4, 2017

For Osteoporosis "I submitted my first review on April 13. Today it's June 4th and still SUFFERING with daily pain from the drug."

• Ann...
• May 30, 2020

For Osteoporosis "Agonizing severe pain in thigh muscle. Unable to walk after subcutaneous injection. No analgesics reduce pain. How long will this go on for?"

• BJa...
• Taken for 1 to 6 months
• December 26, 2019

For Osteoporosis "I am a 76-year-old female. First shot of Prolia on Nov 1, 2019. Side effects started after 3 days. I have always had very low BP. I felt so bad for 2 weeks, someone took my BP and it was very high. Other side effects include joint, shoulder, neck, and knee pain. Day and night sweats are very severe. My side effects aren't nearly as bad as some, so I shouldn't complain. Will not get a second shot."

• BJa...
• Taken for 1 to 6 months
• December 26, 2019

For Osteoporosis "I am a 76-year-old female. First shot of Prolia on Nov 1, 2019. Side effects started after 3 days. I have always had very low BP. I felt so bad for 2 weeks, someone took my BP and it was very high. Other side effects include joint, shoulder, neck, and knee pain. Day and night sweats are very severe. My side effects aren't nearly as bad as some, so I shouldn't complain. Will not get a second shot."

• jdl...
• Taken for 5 to 10 years
• October 13, 2018

For Osteoporosis "I had been fighting osteoporosis for years when Prolia was suggested. I was on it for about six years. Then a change in doctors at the medical center caused a short delay. In a few weeks after that shot was due, I had three terrifically painful vertebral compression fractures. Now, eight months later, I'm a semi-invalid in the sense that I cannot be upright (sitting or standing) for more than an hour or two before the pain becomes more than I can bear. I was formerly very active; now my life is extremely confined. The more I learn about this drug, the worse I see that it is. My doctor and I have reported this to the FDA. Amgen has no advice as to how to get off safely. 'Ask your doctor,' they tell me. So far, the docs have been unable to show me a safe way to get off this horrible drug."

• Puf...
• February 3, 2016

For Osteoporosis "Severe leg pain, cramping in legs and feet, bruising. Not a good med for me."

• Lui...
• Taken for less than 1 month
• September 15, 2020

For Osteoporosis "Prolia has given back pain so that it feels like it is going to break. Pains in my arms, legs, and hands."

• Bac...
• Taken for less than 1 month
• July 12, 2019

For Osteoporosis "I found that after having one injection of Prolia, the side effects were worse than the possibility of maybe breaking a bone. I had muscle and joint pain, back pain, vertigo, hip pain, and just felt flu-ish for more than one month after the injection. I now have diarrhea. I will not be taking it again."

• Ter...
• January 28, 2017

For Osteoporosis "I love the twice a year shot. The company is awesome and very helpful. But... 1st shot no side effects, 2nd shot left groin pain for about a week, 3rd shot and now right-sided groin pain since October that goes to my thigh, hip, and pelvic bone. Pain is severe at times. Also, thyroid problem is worse (not sure if related) and right side lower back pain. I can no longer take the medication."

• Ter...
• January 28, 2017

For Osteoporosis "I love the twice a year shot. The company is awesome and very helpful. But... 1st shot no side effects, 2nd shot left groin pain for about a week, 3rd shot and now right-sided groin pain since October that goes to my thigh, hip, and pelvic bone. Pain is severe at times. Also, thyroid problem is worse (not sure if related) and right side lower back pain. I can no longer take the medication."

• Lac...
• November 24, 2019

For Osteoporosis "I’m so sorry I ever took Prolia shots. After 4 injections, I am in constant terrible pain. I am 66 years old and was so healthy and mobile before the Prolia. Now, leg, hip, arm, and jaw pain. Barely walking now. Taking physical therapy but no relief. This drug should NOT be on the market!! Does anyone know if, after discontinuing the Prolia, this stuff ever leaves our bodies?"

• Jas...
• Taken for 6 months to 1 year
• June 12, 2019

For Osteoporosis "I was on Boniva for 10 years with no improvement in my bones. My doctor switched me to Prolia shots. I took my first shot of Prolia in January 2018 and developed severe mouth ulcers, sloughing of my gums. I could not handle spice or salt, and my nutrition fell. At that time, I did not associate it with Prolia. I took my second shot in August, and my mouth ulcers flared up. Severe ulcers in the gums, upper palate, back of the throat, and nasopharynx area. My mouth had grey, purple, and white patches. I was unable to eat. I also developed severe jaw pain, bone pain, and muscle weakness. For three days, my low back, hips, and legs froze, and I was in excruciating pain and could not walk. I was in bed with ice packs and anti-inflammatories. I was frightened. I have stopped Prolia. It has been more than a year, and my mouth ulcers have not healed. I am now being treated at a university hospital. This is not a safe medicine and should not be prescribed."

• Cat...
• Taken for 2 to 5 years
• April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."

• Cat...
• Taken for 2 to 5 years
• April 29, 2019

For Osteoporosis "I have had 6 Prolia injections. With the first 5 injections, I had muscle pain for a few weeks. This was relieved with ibuprofen. I had my 6th injection in February 2019. One week after the injection, I started experiencing severe hip pain. As the days went on, the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice, and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months, the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug, I was a healthy, active woman."