Prolia and Joint Pain: What Users Say (Page 2)

• Anonymous
• December 28, 2017

For Osteoporosis "After my 3rd injection, I did get some horrible side effects, the worst is the intense itching over my entire body, including my ears and head. It has taken over my life. Back pain, muscle pain, joint pain. I cannot do a normal day's work. I am hoping that the drug will wear off. I will never ever use this awful drug again. It should be removed from the market after reading so many negative comments. I am not alone."

• Dee...
• Taken for 10 years or more
• March 24, 2025

For Osteoporosis "I was diagnosed with severe osteoporosis at 49 years old. I had no history of broken bones but had been thrown into early menopause from surgery at 45 years old. I was first prescribed Fosamax and took that weekly for a year but had adverse effects, so it was suggested I try Prolia, a twice-yearly shot. Thirteen years later and I have nothing negative to say about the drug. I have had no fractures, and I have fallen many times over the years, due to my own stupidity, and always bounce back up with no fractures. I do not have a widow's hump on my back, and I have not had joint pain that I can contribute to Prolia. When first diagnosed, I was told that my bones were those you would expect to see in a 70-80 year old. Since starting Prolia, my bone density shows significant improvement. People will always leave negative reviews but seldom leave reviews if they have no issues with a drug. Prolia has definitely been beneficial to me, and I will continue as long as needed."

• Joa...
• May 3, 2021

For Osteoporosis "After a severely painful experience with a Reclast infusion (which are once per year), I was put on Prolia injections every six months. After a yearly infusion of Reclast and two 6-month intervals of Prolia, I have pain in my joints, muscles, groin, tendonitis in my Achilles tendons and thumb, headaches, nausea, confusion, weakness, fatigue, at least 40 pounds of weight gain, and severe back and hip pain. Before, I was on the go all the time, walking, exercising, and busy constantly, now I don't feel like doing anything because I never feel good and hurt all the time. Needless to say, I canceled my next injection and will take nothing for the osteoporosis. Even though I have a pretty good chance, even more so now, of having a fracture since I took the injections. Can you believe this? When you stop taking Prolia, you are more at risk than you were before you took it! Thanks to all the doctors that only think of how much money they can make off of someone instead of thinking of their health."

• Mad...
• December 14, 2017

For Osteoporosis "Betty (83 yrs old) was given this drug in the hospital after a hip replacement. Apparently, this drug should only be given if other treatments for osteoporosis don't work, but Betty was never given any other treatment for osteoporosis prior to denosumab. Since receiving the drug, her quality of life has significantly deteriorated. She has required 12 weeks of PICC line antibiotics because of a staph infection at the site of her hip replacement, and 12 weeks of oral antibiotics because of a urinary tract infection. Other symptoms include loss of appetite, weight loss, aching joints, weakness, and three hip dislocations. I would not recommend this drug."

• No ...
• Taken for 1 to 6 months
• May 4, 2022

For Osteoporosis "I had my first shot of Prolia in Feb 2022. No immediate observations. However, within 3 or 4 weeks, hair started falling out in handfuls, noticing joint aches and mild headaches, lasting days. I have lost half of my hair volume, and I had thin hair to begin with. When I researched Prolia since the hair loss, it said hair loss was reported 'after' the trial. I was told, literally, no side effects from my doctor. It has been around for years and is very safe. Now I read these responses. My fault, I never researched this in advance and trusted my doctor. I will not take any more pharmaceutical options. Load myself with calcium (diet and vitamins) and go back to nature. I knew better. No more for me!"

• San...
• February 26, 2023

For Osteoporosis "I have experienced increased fatigue, joint pain, and GI upset. I never should have agreed to take this. I also have lupus and achalasia. Will not go through with the fourth dose. Will request other medication. Have yet to have a follow-up on bone density."

• San...
• Taken for 1 to 6 months
• March 6, 2022

For Osteoporosis "I received the Prolia shot 12/29/22. Eight days later, I started having all the side effects, my arms, legs, back, muscles, and joints hurt. 3/4/22, I had an appointment at the hair salon. I was told that I was losing hair. After shampooing, I was given the hair that fell out. I was told by the hair salon not to take any more Prolia shots and to call my doctor regarding all the side effects that I had endured. Prolia should be taken off the market."

• She...
• Taken for 1 to 6 months
• August 2, 2021

For Osteoporosis "Horrible drug. I felt my doctor was overbearing and wanted me to take Prolia. I have been miserable ever since. Bone, joint, muscle pain, difficulty walking. Extreme fatigue. Some days I feel like I am actually dying, nausea, bowel problems. My quality of life is definitely worse. Never again. Only took one injection."

• Lor...
• April 4, 2019

For Osteoporosis "Pain in legs, particularly in thighs and knees."

• una...
• April 10, 2018

For Osteoporosis "I have only had one shot of Prolia, but I haven't felt well since then. My symptoms are intermittent fever, shivers, bone and joint pain, severe fatigue, and jaw pain."