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Prolia for Osteoporosis User Reviews (Page 3)

Prolia has an average rating of 2.7 out of 10 from a total of 322 reviews for the treatment of Osteoporosis. 15% of reviewers reported a positive experience, while 78% reported a negative experience.

Reviews for Prolia

  • Windy
  • Taken for less than 1 month
  • June 26, 2019

"After refusing this for the past 2 years. I finally relented and had the shot about 2 weeks ago. I felt ok for the first 3 days, after that I experienced severe headache with immense fatigue that lasted for 2 days. The headache passed but still much fatigue, muscle pain & burning in arms & legs, lower back pain, ankles & hips. I should have followed my instincts. I am 66, do have osteoporosis, supposed bones of an 80 yr old). I will not be continuing with this."

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  • Cyd
  • Taken for 1 to 6 months
  • January 16, 2020

"I had my first Prolia injection in October and will never have another one! I now live with constant jaw pain, joint pain and chronic fatigue. I’ve had to cut out many activities because I feel horrible and can barely get through my exercise class... my oncologist recommended I start on a bone strengthener in case my breast cancer spread. However, I have no evidence of cancer in my breast or anywhere at this point and refuse to feel this bad from a medication. Ladies, do your research before you follow everything your health care provider suggests!"

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  • MRano
  • Taken for 1 to 6 months
  • February 3, 2020

"Since Prolia I experience intense muscle and joint pain and stiffness in my hips, thighs and down my legs after exercise such as walking, running climbing stairs, cycling or gardening. The pain starts during the exercise activity but grows in severity in the hours and days following depending on how long the activity was and how demanding. I have changed from being a very active person to someone who worries about all events involving weight bearing exercise because of the subsequent pain and discomfort which effects my sleep and rest. I am waiting and hoping the side effects will were off as time goes on. I have decided not to continue with the treatment unless I get reassurance from health care professionals that this is a temporary side effect and the benefits will be worth such as, the deterioration in my bone density subsides. As it is I have advanced osteoporosis."

2 / 10
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Frequently asked questions

  • GramJ...
  • Taken for 6 months to 1 year
  • June 27, 2016

"After getting my 2nd Prolia injection, I've had the worst 4 months of my life!! Within a couple weeks, I went from a very young 70 yr old to a 90 year old woman. My back and hips have been so painful, that I have to wear a stiff back support to be able to move. Even with this, I can't stand up straight. I am awakened at night because of the pain and I can't turn over in bed. I am constantly achey and tired. Before Prolia, I was extremely active. I worked with a personal trainer twice a week for six months, before the 2nd injection, but now, I have probably lost all the muscle, strength and flexibility I gained. I put my gym membership on hold, until I can move, again, without pain. Prolia is the worst!!!!!"

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  • Ouche...
  • May 28, 2016

"This has been the worst experience of my life. Two shots of Prolia and nothing but constant pain. Every bone in my body hurts, literally. I feel just awful all day long. Tired, washed out, constant pain that has been, at times, debilitating. Had to use crutches for two days when I developed severe hip pain and again when I developed sever knee pain. I am eating ibuprofen like it was a bag of M & M's. My cholesterol went high and I have never had a problem with cholesterol in my life (found out that it was yet another side effect). I have been to the ER twice and the walk-in clinic three times since starting Porlia. Two shots and I am done with it, no more."

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Are you taking this medicine?

  • Tline
  • Taken for 1 to 2 years
  • February 15, 2020

"I have osteoporosis. I just had my third injection Feb. 14 2020. Prolia is working great for me. I was having severe pain with walking and losing bone density. I now walk with no pain and my bone density has increased. I have had no side effects other than a feeling deep in my bones fur the first couple days after injection which slightly aches. My quality of life has greatly increased. I highly recommend this for anyone with substantial bone loss and experiencing pain."

10 / 10
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  • Suse
  • Taken for 6 months to 1 year
  • January 20, 2020

"I had my second shot of Prolia January 2017. I experienced SEVERE bone pain and many other horrible side effects. I still suffer from many of those side effects today January 2020 and it has completely changed my life for the worst. The effects of the drug never leaves your system and I will never be the same."

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More FAQ

  • DMD
  • February 20, 2016

"About 3 days after my Prolia shot, I had severe pain in my lower back, right side. Very different from regular lower back pain due to aging. My doctor prescribed physical therapy ( not believing it was due to the Prolia injection) which provided temporary relief. But guess what!!! At the 6 month point, when the Prolia was out of my system, THE PAIN WENY AWAY. Duh. In the past I took fosamax (for 6 yrs) with no side effects. But...I am done with patent medicines. Am reading the book Your Bones, and plan on following their "natural" approach. I did report my experience to the FDA; my doctor (who I really like) didn't react very seriously to my concerns, only listed it as an an allergy on my chart. Don't docs ever talk to the FDA????????"

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  • angry...
  • August 25, 2015

"HORRIBLE side effects! Loose tooth, needed extraction. Dentist found a healthy root, no problem with tooth. Lumps formed in several places. Rashes, shortness of breath. Hoarseness, headaches, joint pain...many more complaints."

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  • Aussi...
  • May 27, 2015

"I , too, had the constant itching and felt like something was crawling on me. I used Gold Bond extreme moisture lotion which helped somewhat. I gained 15 pounds in a matter of 2 weeks, shortness of breath on exertion, and confusion. This was only my first injection and I am due for a second in 2 months but not sure I want to go this route again. This is a monoclonal antibody not a drug and it affects the body differently than a drug. There is no antidote for this if you have a reaction, so you are stuck with the problems for quite some time."

4 / 10
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  • DeDub
  • Taken for 1 to 6 months
  • July 10, 2019

"After going through numerous cancer treatments my doctor insisted that I take a Prolia Shot. BIG MISTAKE My jaw bone is deteriorating. I am losing teeth and now in the process of having to get DENTURES. Their should be a class action law suit as I would be the first to sign up. PLEASE, PLEASE think twice about taking this!!"

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  • Anonymous
  • October 16, 2016

"one shot in march 2016 and have experienced the worst seven months of my life, begun with a headache so bad i had an MRI three weeks after the shot another two weeks before the headache stopped then the infections started ear ,bladder ,kidneys and chest it has been a living hell ,cost a fortune and i cant even translate the pain and suffering, it would take a book that no one wants to read and its not done with me after seven months have a chest infection now that i can not get rid of ,worst experience of my life !!!"

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  • Janet...
  • Taken for 1 to 6 months
  • May 20, 2023

"I have found my back pain is worst than ever, my immune system has declined, my cholesterol went way up, I developed a skin rash, and I still have a lack of appetite, muscle pain, headaches, nausea, swelling, jaw pain, chills, mouth and legs tingling, pain in my arms, sore throat, trouble sleeping and more pain. I do not recommend the Prolia injection. It is bad, bad, bad you start feeling miserable because the pain is unbearable."

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  • RNano
  • Taken for 2 to 5 years
  • August 4, 2019

"Prior to Prolia , I completed bisphosphonate therapy initially for osteopenia which worsened to osteoporosis with a BMD of -2.9. I find Prolia to be an effective medication but with a price. Starting in March 2016, I received my shot with minor bone discomfort. Three months after my fourth shot in, March 2018, I was diagnosed with cellulitis of my left arm. I continued on Prolia, as my BD scores had improved to -2.6 and I had less back and hip pain. By September 2018, after 6 months of gastroenterology problems, I consulted a specialist. Completing a colonoscopy , I was diagnosed with microscopic lymphocytic colitis. Afraid to stop Prolia, as discontinuing this drug increase the risk of broken bones, including spine. Recently, April 2019, I was diagnosed with Atrial Fibrillation Strike three Do not start this drug I am an extremely active adult, biking and hiking and now what do I do? My endocrinologist denies Prolia is the culprit."

6 / 10
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  • Very...
  • Taken for 1 to 6 months
  • January 20, 2020

"My GP recommended I have the Prolia injection for my bone density. I read about the side effects but hadn’t seen this website, so went ahead on 5 Nov 2019. Within 24 hours I experienced terrible pain in my left arm. The pain was in the bone. This occurred two days running before it subsided. I saw my GP two days later and told her of the pain and I said never again will I have this injection. She agreed. Pain went away but other symptoms attacked me. Extreme irritability, lethargy, bloating, loss of appetite. Visited my GP twice about side effects. Second time (10 days ago) she recommended a strong probiotic. I took and in two days the bloating had gone and my appetite began to return. The Prolia drug had attacked the good bacteria in my gut. After 10 days on the probiotic I feel normal again. Three months and two weeks and it is out of my system."

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  • Layla...
  • July 28, 2016

"After two shots, had swelling in both elbows, stiff neck and pain. I am not sure prolia is the cause but I will not risk it again or any drugs for osteoporosis. My immune system was compromised too and I have had several illnesses. I went from an active fit person to not being able to perform simple everyday tasks without big pain. I have had the worst 6 months of my life. Avoid this medication!"

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  • Stone...
  • Taken for 2 to 5 years
  • February 16, 2021

"Had my fifth shot of Prolia December 8th 2020. Will definitely not be taken this drug again. I found with each passing injection the symptoms became more severe. I'm after going from a very fit person to totally disabled. Muscle weakness in thigh muscles and arms. Extreme pain in shoulders and arms. Very tight rib cage muscles. No energy. Extreme nausea. Discomfort in my throat. Dry cough at night time. Muscle stiffness twitching cramps and spasms. Severe right hip pain and sciatica pain. All of these started with taking prolia."

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  • Jill...
  • September 17, 2016

"Please do your homework before taking this awful drug. My Dr. never told me about any potential side effects and I got them ALL. So sick for months with severe lower back pain radiating around the front. Severe upper GI issues with nausea and haven't been able to eat for months. Lost 15 lbs so fast that my skin is all wrinkles and lose. I look 20 years older than before taking this drug. Spent so much time at Dr's trying to figure out what was wrong with me and all tests came back negative. Only possible thing is Prolia shot. Headaches, chronic fatigue, poor sleep. Ended up in ER thinking I was having a heart attack...pain was debilitating. At least I found out my heart is good. Have had 3 additional episodes like this. BEWARE"

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  • Hank
  • December 1, 2018

"My wife was scheduled to take a prolia injection for osteoporosis, but after we both read lots of reviews, she cancelled her appointment. Thank you for this valuable insight of the risks and benefits. Now, we do not know where to go or what to do about her osteoporosis, but it is time for further research on these drugs. Taking a “drug from hell” is certainly not the answer."

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  • BJano
  • Taken for 1 to 6 months
  • December 26, 2019

"I am 76 year old female. First shot of Prolia Nov 1, 2019 Side effects started after 3 days. Always have had very low BP. Felt so bad for for 2 weeks, someone Took BP and was very high. Other side effects joint, shoulder, neck and knee pain. Day and night sweats are Very severe. My side effects aren't Nearly as bad as some so I shouldn't complain. WILL not get a second shot. "

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  • CMoore
  • July 10, 2016

"Can anyone tell me how long it stsys in your system please? Had only one injection, won't have another but want to know if these awful side effects will subside in time now that ive decided to stop them. Thankyou."

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  • Judith...
  • Taken for less than 1 month
  • February 14, 2017

"Had first Prolia shot 9 days ago and it has been debilitating. Will not get another! It is not worth the pain and discomfort. I have had major bladder problems, chills, fatigue, all the bones in my back ache, I can't sleep at night. I have to take Advil to relieve back pain or I can't function. Can't leave the house for long because of bladder issues. I called my Oncologist about possible bladder infection and was promptly advised that was not a side effect of Prolia even though bladder issues was listed as a possible serious side effect! I hope I don't have to suffer from this one shot as long as others have - it is truly life style restricting. I wish I had read these reviews before getting my 1st (and ONLY) shot."

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  • Healthy...
  • Taken for 6 months to 1 year
  • December 12, 2019

"I have osteoporosis with no symptoms as I’m extremely fit and healthy. I resisted Prolia as I take no drugs at all. After one year bone density improved 7.6pc hip and 2 pc spine. A week ago my gum was bleeding and I sorted it. Today I had third injection. I’m writing this also to see if they publish positive stories as all that I just read were mostly negative. My brother is a doctor and encouraged me to do it. I weigh 56 kg . I have always eaten good food and stayed slim and well. So far so good for prolia the only drug I have ever taken."

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  • Cindy
  • November 4, 2019

"I am stuck on this drug Prolia after 8 years on one injection to the stomach twice a year. I am too scared to continue and too scared to stop. My specialist has said we will review it at the 10 year mark. I worry about how my bones will be at the 10 year mark. I am 71 years old and was healthy except for two fractures in 2 years. I wish I had not started the drug in the first place. I wake up with pain during the night. I seem to need to sit down after walking in the shopping centre for 15 minutes. My thick hair has been falling out for the last 3 years. My skin and eyes are very dry. I have a wrinkled face of someone 15 years older. I am concerned that I will be in a wheelchair at some stage. I go to an exercise physiologist for strength and resistance training it has helped a lot. However over 1 year my abilities have reduced due to severe attacks of vertigo. I have also evidence (through MRI) of a few small strokes which I was not aware of. I only add this in case useful for others"

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  • Mary...
  • Taken for 1 to 2 years
  • April 17, 2016

"Prolia shot given July 26, 2012!. Immediately had every dermatological problem listed in the ad:Itching, rash all over body except for face, extreme pain, dry skin, repeated biopsies, thousands of dollars for doctors, prescriptions, lotions and potions. Left calf's skin completely peeled off like the bark of a tree and has never recovered four years later!! Even now it is again broken out in oozing rashes around the ankle, but the entire leg hurts. I must keep the hair on my legs shaved very close or when I am exercising in the Y pool, the leg is painful just with the movement of the tiny hairs in the water. The pain is inside as well as on the surface of my skin. These bad side effects continue! Have pictures of early rash available."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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