Denosumab for Osteoporosis User Reviews (Page 4)

• Mary...
• Taken for 1 to 2 years
• April 17, 2016

Prolia (denosumab) "Prolia shot given July 26, 2012!. Immediately had every dermatological problem listed in the ad:Itching, rash all over body except for face, extreme pain, dry skin, repeated biopsies, thousands of dollars for doctors, prescriptions, lotions and potions. Left calf's skin completely peeled off like the bark of a tree and has never recovered four years later!! Even now it is again broken out in oozing rashes around the ankle, but the entire leg hurts. I must keep the hair on my legs shaved very close or when I am exercising in the Y pool, the leg is painful just with the movement of the tiny hairs in the water. The pain is inside as well as on the surface of my skin. These bad side effects continue! Have pictures of early rash available."

• Jan...
• Taken for 1 to 2 years
• April 8, 2016

Prolia (denosumab) "I will never have this shot again. It made my skin loose & wrinkled. Researchers don't have a clue if this helps bones or not. I can tell you I completely reget trying prolia.And hate seeing Blythe Danner doing this commercial."

• Oh M
• May 1, 2016

Prolia (denosumab) "I have been on Prolia for approximately two years. Just this year ( my 5th injection) I did experience sore muscle/joint pain in my hips. About 4 months ago I developed dermatitis around the corners of my eyes, nose, mouth, and along both sides of my neck. I've never had allergies before. Also, I'm dealing with a feeling of deep exhaustion. I'm not sure whether this is due to Prolix. If my next bone density doesn't show marked increase, I will ask my physician for a change in med. one note--I faithfully exercise 3-4 times weekly with a trainer, take calcium, and eat green veggies and foods with calcium/D."

• Diamo...
• April 28, 2016

Prolia (denosumab) "This drug has been a nightmare . I have experienced unexplained bone pain in lower left leg and a breakout of bleeding gums and mouth sensitivity. I did not get any info from prescribing endodocrinologist except that it was a safe drug and that he had prescribed it to his mother! This has been a very expensive lesson in terms of dental cost and extremely detrimental to my health and well- being."

• Tupence
• Taken for 6 months to 1 year
• August 26, 2016

Prolia (denosumab) "I am in the UK and therefore am 'lucky enough' not to have paid for my treatment. However I understand this is a relatively expensive drug for the National Health Service to prescribe. I have had two six monthly doses and I will certainly not be having the third and that is despite having severe osteoporosis . I have experienced no positive results from this drug, only debilitating pain, stiffness and general flu' like symptoms which come and go regularly day and night with no prior warning. My worst experience was a spot on my lower jaw bone that grew until it literally erupted, leaving a 2mm diameter hole in the side of my face. ( 2 months of antibiotics ) I can find no positive feedback to justify this drugs side effects."

• Joey
• Taken for 2 to 5 years
• September 6, 2018

Prolia (denosumab) "Prolia has been an absolute nightmare for me and from the reviews of this drug, I am not alone. I wish I had done my homework before ever taking the first injection. I trusted my doctor! I have suffered most of the horrible side effects of Prolia, real drug Denosumab , now being used for bone cancer patients!! So yes, a form of chemotherapy?? I am not sure my body will ever be rid of this poison and my last shot was 2015!! I have reported it a number of times to to FDA, to no avail. I warn everyone and hope to spare others from the suffering I have and am still going through , BEWARE OF PROLIA !! Hope this post helps someone."

• Reelw...
• Taken for 1 to 6 months
• November 5, 2019

Prolia (denosumab) "On my last visit to the cancer center they put me on a new injection for Osteoporosis (Prolia) and had to sign a form to take and I as a lot of you trusted in your doctors and I took the shot back in September 2019. OMG I was not ready for what I was in for with the side affects, I have no energy, my legs feel like they after 10 steps I have to stop and take a break, my bones hurt all the time and they did any way with the hormone blocker but this just intensified it. I have no appetite, can't sleep and my memory is horrible. I have a very multi-tasking job and it has been heck keeping up with everything. It is all about the god almighty dollars with these doctors and I will not take this drug again. One thing I have found as far as the Osteoporosis is there are classes called Osteo Strong that builds bone in your body naturally and you go once a week "

• shayl...
• March 11, 2017

Prolia (denosumab) "My Mom got this shot a month ago and her life has been hell. Extreme pain that she ended up in the hospital getting injections for pain and on morphine. Extreme headaches to where she can not function along with god awful headaches. Jaw pain, muscle cramps, fevers, stomach issues, bladder issues. short time memory issues, and with all this happening she is now depressed from all the issues which now gives her anxiety wondering if these will go away or not. The sad thing is that not all the symptoms right after the shot. They show up weeks later and no one can tell you how long they will last,"

• Bre
• Taken for 6 months to 1 year
• January 2, 2021

Prolia (denosumab) "Had a wedge compression fracture in August 2019, doctor ordered Prolia injection. Wish I had never had it, developed stomach and intestinal problems, reflux, (never had any problems with that before), pain in groin (a cyst on ovary was found), increased pain in neck, had an increase in blood pressure, pulse rate increased, pain in arms, legs and continue with pain in back, muscle soreness and weakness. Was diagnosed with Barrett's Esophagus in January 2020. Never will allow another injection, and of course doctors don't believe it caused these problems."

• Mazza
• October 16, 2018

Prolia (denosumab) "My doctor gave me the prescription for Prolia yesterday. I explained to her I would research the drug before making a decision. I was horrified after reading ALL the possible side effects. However after reading the above reviews I will never take this drug. Thank you to all the people who wrote reviews. I am shocked that this drug could ever be approved by the FDA."

• Prolix
• May 30, 2016

Prolia (denosumab) "I did not know nor was I given any information on this injection. About 1 month in I experienced hair loss in places. Have a tingling around the lips. I felt very nauseous on and off out of the blue. Am very tired and just cannot get rid of chest infection/cough which just seems to be on loop... I think it's clearing up then it hits again. I will not get this injection again. Nothing is conclusive about the cause of what I am experiencing."

• Patri...
• Taken for 1 to 6 months
• April 7, 2016

Prolia (denosumab) "I had my first injection Oct 2015 and due again in April. Is the 2nd shot any better than the first one. Flu like systems the first couple of days, then constant constipation, acid reflux, extremely tired, itching. My Doctor told me I could not have any dental work done while on this drug, such as root canal. What other drugs can you take ? or is natural the best way. If you speak to naturopaths they claim these drugs throw your entire immune system out. Stay away from injections."

• Anonymous
• Taken for 2 to 5 years
• August 24, 2023

Prolia (denosumab) "I'm having severe pain. Such a dilemma. Degenerative back problems or chronic pain from Prolia...from walking to feeling crippled. It feels like the drug causes severe inflammation. I have eczema, another side effect."

• XGypsy
• Taken for 1 to 6 months
• November 25, 2019

Prolia (denosumab) "This is now 1 year, 1 month from my one and only Prolia injection. Reading the other comments from patients who have had poor to terrible side effects, I am certain that one dose of Prolia likely still lingers in my system and the side effects continue. My bone and muscle pain kicked in with a vengeance and has not abated. Walking became and remains difficult due to body pain and loss of strength/balance/pain in addition to which, my skin rashes causing both pain and itching continue. I regret being talked into taking Prolia even though my osteoporosis remains seriously advanced. All of the side effects continue although I only had the first injection due to the severe reaction that kicked in within a few days. Note: Amgen is recently promoting a "new" drug 'Evenity' ..an almost identical to Prolia...which has major warnings, actual black boxed warning - some even worse than the Prolia warnings. Doctors continue to advise trying the drug. For me , that is not an option."

• Lake...
• Taken for 1 to 2 years
• July 10, 2016

Prolia (denosumab) "Various side effects including fractures in both feet and bad pain and aching in right leg making it almost impossible to walk and keeping me awake and in pain. It is time for my third Prolia shot and I have suffered from this for two months and am no better. This has not been a positive experience but a bad and painful one leaving me unable to get out and preform any daily task or functions."

• Lacy
• November 24, 2019

Prolia (denosumab) "I’m so sorry I ever took Prolia shots. After 4 injections I am in constant terrible pain. I am 66 yrs old and was so healthy and mobile before the Prolia. Now - Leg, hip, arm and jaw pain . Barely walking now. Taking physical therapy but no relief. This drug should NOT be on the market!! Does anyone know, if after discontinuing the Prolia, does this stuff ever leave our bodies?"

• Molly
• Taken for 6 months to 1 year
• November 14, 2019

Prolia (denosumab) "1st Prolia needle ok, 2nd needle within 2 weeks I got so much side effects of joint pain, unbelievable arms legs, even tips of shoulders were sore to touch, I am tired and can’t do what I want to do, my appetite is not good and have lost weight. I should have looked into Prolia side effects. I would not wish this on anyone. My thoughts and prayers go out to anybody who is on this awful drug Prolia"

• Lucy
• Taken for 1 to 2 years
• October 12, 2019

Prolia (denosumab) "My first 2 shots of Prolia were positive and my T score improved 25% in my hips and back from -2.8. I took my 3rd shot in July 2019 & have been having increased pains ever since from my hip folds all the way down to my toes, in my lumbar spine region, and in my ribs. I get severe headaches on & off and experience nausea (extremely like flu) every day. The doctor never mentioned the side effects of Prolia & I trusted him so much I didn’t do any investigating before taking it. I also have what seems like a never/ending cold. Even nasal spray gives very little relief. I’ve been to my NEW GP doctor twice since my 3rd shot, but she has never seen a connection between my symptoms and Prolia. I put a message in MYCHART yesterday saying I am done with Prolia! It’s not worth being sick all the time."

• Slm
• January 1, 2020

Prolia (denosumab) "I had one injection in 2018 and started having side affects the next day. Skin rash and itching, then mouth ulcers, swollen lips and tongue. Pain in feet, legs and hip and fatigue. I would never recommend nor have this drug again. It has been over a year and I still have symptoms."

• Robin
• Taken for 1 to 6 months
• May 15, 2023

Prolia (denosumab) "My first injection of Prolia was on January 26, 2023, and it will be my last! Within 1 day of the injection until now (May 14, 2023) I experienced severe body pain including hip, thigh, groin, swollen knees, severe muscle twitching, blurred vision, hair loss, and the list goes on. So far, I have not experienced ONJ (jaw bone disease). DO NOT USE! I did not research this drug nor was I informed of the side effects by my doctor. Also, you can't just quit Prolia! You have to relay off with another bisphosphonate in order to not have PROBABLE, not possible, spinal compression fractures!! I will be using iv Reclast as my relay drug."

• thewo...
• Taken for 1 to 2 years
• February 19, 2021

Prolia (denosumab) "Please do not consider ever taking this drug. I've learned there are options. As most have said, Prolia is one of the worst drugs on the market - for anything. Took my 88 year old mother in for what may have been her third injection. It destroyed her life beginning that same night of the injection. Could not figure if it was Covid or the injection as the timing was just exact. Negative Covid antibody test proved her problems were from Prolia. Six weeks and four nights in the hospital later and she is still suffering terribly. Class action lawyers? Where are you?! What seems so devious about the drug is that her doctor asked if she was a nursing home resident. This drug seems to be designed for those in nursing homes so that their pain, sleep and everything else described herein can be under 24-hour observation and controlled with other drugs."

• Suz
• Taken for 1 to 2 years
• April 7, 2019

Prolia (denosumab) "I’ve decided to come back to this site to leave an update to my last review. I received my 2nd shot of Prolia January 2017. The side effects were very severe for 9 months. Tolerable now but I realize I will never be the same and will always suffer pain from this medicine. The damage is done and just has to be dealt with. I do not recommend this drug. I believe my Dr took the word of the drug rep instead of doing her own research about this drug as she had never heard of any bad side effects. Please do your research before starting this drug. The damage is permanent ."

• George...
• Taken for 1 to 2 years
• November 18, 2016

Prolia (denosumab) "While the bone test indicated a slight improvement, I don't feel it is worth it. The first time I had the Prolia shot, I had no reaction. After the second shot, my hair began to fall out in bunches. It has continued to fall out and it looks as though I will have to wear a wig. Has anyone else had this problem and does it go away after the drug wears off? I will never take another dose of Prolia and would not recommend it after reading all the negative posts on this site. It would seem that my problem is small compared to others."

• Painf...
• Taken for 1 to 6 months
• June 5, 2023

Prolia (denosumab) "I had my first and last injection on Dec 15, 2022. The first month was fine, didn't notice a thing. But then, my hips became very sore, my muscles hurt and I have difficulties walking without pain management. My bedside table is full of pain relief. I have rheumatoid arthritis and take Rinvoq. It is well controlled, however with the layer of permanent pain, I have no control how well my other medication works. How can they sell a product which after you stop it makes your life even worse. It should not be allowed. I also read through the large study and can't see the benefit of it, when your life turns into a pain management exercise. Just don't take is."

• MaryAnn
• Taken for 1 to 6 months
• May 26, 2016

Prolia (denosumab) "From the start I began to experience side effects. The most bothersome are the extreme sweating episodes followed by chills at least 12 times a day or more. In addition other side effects are more pain in my lower back and hips as well as a rash with associated itch on my upper back. I will never get another Prolia shot!!! Wish I knew there would be so much discomfort!"