Clomipramine and Sweating: What Users Say

• Coy...
• Taken for 2 to 5 years
• March 25, 2022

For Obsessive Compulsive Disorder "This medication is quite literally a lifesaver. I have had debilitating OCD along with bipolar and PTSD since childhood. I have also battled anorexia and exercise addiction for close to 50 years. I was on it for a couple of years about 6 months back, but my doctor took me off of it because it was making my manic episodes much worse. As soon as I went off of it, my obsessions and compulsions came back with a vengeance. She put me on Depakote to stabilize me, then put me back on the clomipramine last night. I could feel the difference as soon as I woke up this morning! I am (and was previously) only taking 12.5 mg, which did help tremendously. I'm hoping that, with the Depakote, I can make it to at least 25 mg to really get rid of it for good. I know that many of you are here because you aren't sure if you want to take the leap and, like me, you are probably obsessing about it. PLEASE push past your fears and give it a try! Dry mouth, sweating, and some mild tachycardia...that's it!"

• Bad...
• Taken for 1 to 6 months
• November 8, 2021

For Panic Disorder "Clomipramine helped to a certain degree, but I have to come off it now due to the hot flushes and the relentless sweating. It was just so uncomfortable to have sweat literally dripping off my face, back, and chest."

• z-d...
• Taken for 2 to 5 years
• March 2, 2021

For Obsessive Compulsive Disorder "Makes my mouth dry and makes me sweat more than normal. Nevertheless, this med has helped to quiet my head to a manageable level to function."

• Mar...
• Taken for 6 months to 1 year
• August 5, 2020

Clomipramine for Panic Disorder "On 100 mg Anafranil, and it makes me calm, and I don't worry about things anymore, but can still have panic attacks. Side effects: makes me sweat when it's warm a lot."

• Don...
• Taken for 2 to 5 years
• July 21, 2020

For Panic Disorder "This medicine, clomipramine, saved my life from panic disorder. It took me six long years to find this medicine. I used to read all the reviews on this site hoping and dreaming I would one day have relief like so many on here. In fact, some days it was my only way of keeping hope. This drug took 6-8 long months to take effect for me. It was slow progress out of hell, but every day was better than the one before. Like the sun coming up, you don't really notice it getting light out. Things that were impossible became possible. My thoughts were quieted and my mind could think about other things besides depression and anxiety. I have been on the drug for 6 years now. My depression and anxiety are gone. Like all gone! Not diminished or tolerable, but gone. My side effects are increased sweating and loose bowels. I am impacted by them, but I would take the trade every day and twice on Sunday. :)"

• Leo...
• Taken for 1 to 2 years
• September 3, 2017

For Obsessive Compulsive Disorder "One of the better drugs I have taken. It sure works - for me, 125 mg completely erased my OCD-related depression and anxiety, but there is a side effects price: excessive sweating, constipation, and reduced libido."

• Pka...
• Taken for 10 years or more
• August 7, 2017

For Obsessive Compulsive Disorder "I have been on this drug for 16 years, and it has been a lifesaver. The side effects were pretty intense at the start, mainly constipation, dry mouth, and I gained 15 pounds. I persevered with the side effects for about 3 months because I just felt so damn normal. The side effects went away, and weight returned to normal. I believe the only long-term side effect is excessive sweating. Oh well, I can live with that! I tried about 9 different meds for anxiety and depression, and none of them gave me any side effects at all. 1 week on clomipramine, and I was constipated big time and had major dry mouth but had joy back in my life! Can't live without it! Cost has gone up in Canada because I believe there are no longer any generic manufacturers."

• Liv...
• Taken for 1 to 2 years
• March 2, 2017

Clomipramine for Obsessive Compulsive Disorder "I have been taking Anafranil 100mg for a year now and it has changed my life. I have battled with OCD, severe anxiety, panic disorders, and intrusive thoughts since I was young. While trying different drugs, finally at the age of 40, one drug works for me and this is it. I still have the 'thoughts' but instead of obsessing over them, they pass by like moving cars. The side effects are bothersome: dealing with constipation, bloating, sweating, insomnia, twitches. I don't believe I can ever function without this medication and instead maybe lower my dosage to see if it reduces the side effects."

• UK ...
• Taken for 2 to 5 years
• December 9, 2016

Clomipramine for Obsessive Compulsive Disorder "I have severe early onset OCD. I have found that clomipramine (Anafranil) has taken the edge off of it. I've been taking it for 4.5 years, SLOWLY building up to 200 mg, but have found that the side effects of this medication to be too much, in particular the excessive sweating. I am regularly dripping with sweat to the point I have been asked if it is raining outside because I'm soaked. I'm thinking of coming off of it because the sweating is exacerbating the OCD as I now have obsessions about it, and I'm constantly worried about people looking at me because I'm sweating so much, which isn't very feminine. I've tried to come off of it a few times, but every time I do, my OCD regresses into overdrive-highlighting how effective it is for OCD."

• Adr...
• August 18, 2016

For Panic Disorder "I'm a Brazilian boy, and I suffer from GAD, panic, and depression. I was trying to find an alternative to Effexor (which was great but caused sexual problems). After using lots of meds without the same success, my doc prescribed me clomipramine. It did work!!!! And without the sexual side effects. But it has other side effects that I couldn't take, like... everything tasted like rotten meat, my mouth and eyes were always dry (even drinking loads of water), my muscles felt so weak that sometimes I thought I would not have the strength to get out of bed, hands and chin trembling, sweating like hell... it completely dehumanized me. But if you're looking for something to kill your panic, yeah, this will work probably at the smallest dose."

• RJR...
• August 4, 2016

For Obsessive Compulsive Disorder "I have tried many of the SSRIs with no success. I was on a tricyclic many years ago with great results. My doctor put me on Clomipramine, and the results were good. I saw a good improvement in racing thoughts with a decrease in anxiety. I should have asked for this drug in the first place. The side effects are rough, though. I experienced excessive sweating, dry mouth, blurry vision, constipation, postural hypotension, and impotence/ejaculatory issues. I remember these effects from years ago when I was on a tricyclic. I would rather live with it than be paralyzed with anxiety."

• lau...
• Taken for 6 months to 1 year
• July 27, 2016

For Obsessive Compulsive Disorder "On 75 mg is enough for me, some side effects: sweating and constipation. Tried 3 different SSRIs, and this was the only one I could stick with! Life saver, highly recommend."

• Tha...
• Taken for 1 to 6 months
• June 10, 2016

Clomipramine for Panic Disorder "I had a break up and was suffering extreme anxiety and depression. I was not functioning at work, in life, and suffered for several months. I was getting worse and worse, not sleeping, and finally broke down and decided to take an antidepressant. After about 4 days, something changed a little. Within two weeks, my anxiety went away, and I began sleeping again as well. I weaned off of the Ativan I was taking, and this drug saved my life. I probably would have been hospitalized if I didn't go on it. Side effects: sweating (a lot), constipation, and of course, ejaculatory issues, but I could still have sex with my partner. These side effects were easy to deal with when compared to my anxiety. Saved my life!"

• Too...
• Taken for 1 to 6 months
• April 14, 2015

For Depression "I had several attacks of depression in the last 25 years following stress at work with variable severity. All of these attacks respond well to Anafranil in 3-5 weeks of therapy with some side effects like sweating and tremor during the first 2 weeks. Then I take a small dose for another several weeks and tapering it without problems. During the last attack of depression, I made a mistake when I started treatment with Zoloft, depending on the opinion of a psychiatrist who said to me that this drug is very good with fewer side effects in comparison with the 'old drug Anafranil with unpleasant side effects,' as he said. I'm on Zoloft with up to 150 mg for the last 6 weeks without significant improvement. I decided to stop this drug and return to my Anafranil."

• Anonymous
• March 5, 2013

For Obsessive Compulsive Disorder "I had suffered debilitating OCD from the age of six, and Clomipramine has improved my condition 95%. It also handles my chronic sciatica beautifully. Diminishes pain by about 70%! Constipation and sweating are my only side effects. And that's not much of a problem. I'm 45 and finally enjoy life."