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Clomipramine and Sexual Dysfunction: What Users Say (Page 2)

Brand names: Anafranil

Reviews for Clomipramine

Commonly mentioned side effects
  • Mr ...
  • March 9, 2016

For Obsessive Compulsive Disorder "Clomipramine began improving my OCD symptoms within a couple of weeks and seems to have all but eliminated my intrusive, repetitive thinking at this point. I still have off days from time to time, but my therapist and doctor both agree that's to be expected. This stuff has taken me from not being able to function to getting back to my life. The only downside is I have experienced some difficulty reaching orgasm. Not every time, but from time to time. Erections are fine and libido is actually increased - due to just feeling so much better. All in all, that's a small price to pay for what feels like a restoration of my basic sanity."

8 / 10
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  • DFr...
  • Taken for 1 to 6 months
  • February 28, 2016

For Obsessive Compulsive Disorder "The first 2 weeks were kind of difficult for me. Lots of side effects and very little results. Hot/cold flashes, lethargy, tiredness, dizziness, sexual dysfunction, and so on. After a month, the effects of clomipramine started to really kick in. It was effective against depression. Instead of going to bed every night hating myself and wanting to die, that only happened once a week. It reduced some (not all) of my OCD, particularly my obsessions. On the downside, it effectively made me bipolar. At one moment, I felt like Jesus. The other I was severely suicidal. I always had mania and depression, but not to this extent. Had to go off it. Lots of pros. Lots of cons. It works. But will it work for you?"

6 / 10
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  • hel...
  • November 11, 2013

Clomipramine for Obsessive Compulsive Disorder "It has worked really well for my severe OCD, depression, anxiety, and panic. It stabilizes my mood too. The side effects are awful for me, though. Sexual side effects (like my genitals are numb) and severe constipation are the two side effects that keep me from being on a more therapeutic dose. At 100mg, the side effects are bad. At 50mg I'm OK in terms of side effects, but the benefits are minimal. I will be going up to 75mg and see how that goes. In the past, I had been on 150mg and then 200mg. I had never been happier. I think I may have been too happy rather than normally happy, though."

7 / 10
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140 Report

Frequently asked questions

  • Mac...
  • Taken for 10 years or more
  • March 7, 2013

Clomipramine for Obsessive Compulsive Disorder "I have used Anafranil on and off for 30 years. Each time, it has worked superbly. I stop and then start again about 2 years later, for a period of about 4-6 months. Presently taking 200 mg along with Beta Blockers - the best experience ever: I am happier, more confident, and less anxious than ever in my life. Anafranil side effects are sometimes bad: loss of appetite, sexual dysfunction, and blurred vision tend to hit me badly. Also, can take 2-3 months before they really work. But worth the wait, even though it feels for a while as though it makes you feel worse. Outstanding medicine - a lifesaver!!"

10 / 10
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239 Report
  • PGc...
  • Taken for 1 to 6 months
  • March 5, 2013

For Obsessive Compulsive Disorder "Miracle! I had obsessive thoughts that I recognized and could not get rid of. Tried years of therapy and one year of Lexapro with no results. The thoughts had cost me relationships in the past and were starting to ruin my latest and best one also. I finally tried Clomipramine. Even at the low dosage of 25 mg, I started to see results after two weeks of taking it. The side effects are a drag, but they start going away. Worst one for me is the anorgasmia, though which is getting better slowly."

10 / 10
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  • Sco...
  • Taken for 1 to 6 months
  • February 7, 2013

Clomipramine for Obsessive Compulsive Disorder "Anafranil: Most likely the best medicine for obsessive-compulsive disorder overall. Yet each person has their own body chemistry/energy issues. Most people with OCD need about 100 to 200 mg at night. The key is to GRADUALLY go up in dose. This will give your body TIME to ADJUST to Anafranil. I am now up to 150 mg after 3 months, and I am feeling much better. Much fewer OCD thoughts. Yes, sexual side effects... as with any OCD medicine. I used to take a high dose of Paxil for 8 years and it just wore out, OCD came back. I think I will try Anafranil 200 or 225 mg, stay on it for a year, then see how I do as I try to wean down the dose to 50 or so."

9 / 10
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  • Anonymous
  • March 21, 2012

Clomipramine for Obsessive Compulsive Disorder "After three years on different antipsychotics, I started taking this finally to some relief. I have been taking it now for about six months. It is still working well for obsessing, but the side effects are starting to add up. I have steadily gained weight. Severe dry mouth at first, not so bad now though. Total anorgasmia fixed by Viagra, and uncontrolled twitching. It sounds bad when I write it down but compared to the antipsychotics it's much better. I still feel better than I have and so much happier."

8 / 10
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  • kma...
  • February 24, 2012

Clomipramine for Panic Disorder "Outstanding medication for obsessive-compulsive stress disorder, panic, agoraphobia. I have been on this medicine for 15 years, and it has eliminated my panic attacks, anxiety, and I am able to leave the house without fear. Side effects include rapid heart rate, dry mouth, sexual dysfunction, and hypotension. I take Anafranil at night. There is absolutely no weight gain, in fact, I lost 50 lbs. I did switch to Zoloft with no success and am back on Anafranil. There were no withdrawal symptoms when tapered off. This is one of the best meds in the TCA class and works better than the new SSRIs for me."

10 / 10
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  • hea...
  • November 17, 2010

Clomipramine for Obsessive Compulsive Disorder "Works well for OCD, wonderful for body pain, and moderate for depression (it takes 6-8 weeks for me to see any effect), but the side effects are not pleasant: dry mouth, fatigue, drowsiness, difficulty concentrating, and anorgasmia."

9 / 10
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67 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.