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Anafranil and Insomnia: What Users Say

Insomnia: mentioned by 6 users (6.1%)

Based on user experiences from 98 Anafranil reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 15.3%
sexual dysfunction 11.2%
constipation 8.2%
weight gain 8.2%
insomnia 6.1%
tiredness 6.1%
anxiety 5.1%
sweating 4.1%
depression 3.1%
dizziness 3.1%

Reviews for Anafranil

Commonly mentioned side effects
  • Sha...
  • January 17, 2015

For Obsessive Compulsive Disorder "I take this medication for obsessive-compulsive disorder and anxiety. This medication has been the saving grace of my life! The only side effects I have experienced are insomnia when I first started it or upped a dose, but it goes away within a few days. And dry mouth. But I feel so much better freed of my obsessional thoughts I don't care! I take 150 mg a day and have been on it for 5 years. No other medicine has ever been so effective for this long, and believe me, I have taken everything you can name!"

9 / 10
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  • Liv...
  • Taken for 1 to 2 years
  • March 2, 2017

For Obsessive Compulsive Disorder "I have been taking Anafranil 100mg for a year now and it has changed my life. I have battled with OCD, severe anxiety, panic disorders, and intrusive thoughts since I was young. While trying different drugs, finally at the age of 40, one drug works for me and this is it. I still have the 'thoughts' but instead of obsessing over them, they pass by like moving cars. The side effects are bothersome: dealing with constipation, bloating, sweating, insomnia, twitches. I don't believe I can ever function without this medication and instead maybe lower my dosage to see if it reduces the side effects."

8 / 10
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70 Report
  • Anonymous
  • October 4, 2017

For Obsessive Compulsive Disorder "This medication is absolutely life-changing. After years of suffering from anxiety and OCD with mostly intrusive racing thoughts that caused insomnia, this medication was a miracle! I had tried so many failed medications and therapies that I became hopeless. I was prescribed this medication after being hospitalized, and I have never been back. That was over 2 years ago. It took 4 weeks to work, please give it time. I feel like I have my life back!"

10 / 10
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62 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • May 17, 2018

For Obsessive Compulsive Disorder "I have been depressed for years and just recently discovered I had OCD. Only 1 or 2 medications would help, and then they would stop. I tried holistic supplements and diet, and nothing helped. I was becoming hopeless, and then I heard about someone who tried Anafranil. I started on 25 mg and gradually went to 150 mg. Finally, after 4 or 5 weeks, I started feeling better. I wanted to get up and go to work in the morning. Side effects were a dry mouth, insomnia, and some dizziness, but I'm hoping they will go away with time. I would recommend it."

10 / 10
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44 Report
  • Rlw...
  • Taken for less than 1 month
  • April 4, 2022

For Obsessive Compulsive Disorder "I’d love to know how anyone else went on this drug? I’m only on 25 mg and also on Concerta 18 mg for ADHD, so I’m basically OCD/ADHD. I have been getting really bad insomnia, but I do find it is helping. I take it in the morning at the moment because when I first started, I found it kept me up worse when I took it at night. I will eventually increase. I get dry mouth, but it has also fixed my IBS. Please feel free to share experiences if the insomnia side effect goes away. I’m on week two now."

8 / 10
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6 Report
  • shb...
  • Taken for 1 to 6 months
  • May 27, 2013

"Started out good, then headaches, then sleep problems. After that, muscle spasms, also weakness, although I started feeling better to start with as far as my mood and depression."

4 / 10
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20 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.