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Cetirizine and Sleepy: What Users Say

Brand names: Zyrtec, Aller-Tec, Quzyttir, Equate Allergy Relief, All Day Allergy, Children's Allergy Relief, Zyrtec Hives, PediaCare Children's 24-Hour Allergy, All Day Allergy Children's, Alleroff Aller-Tec Children's …show all brand names

Sleepy: mentioned by 12 users (4.1%)

Based on user experiences from 294 Cetirizine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 21.8%
itching 20.1%
rash 8.8%
tiredness 8.8%
anxiety 5.1%
headaches 4.4%
sleepy 4.1%
depression 3.7%
fatigue 3.7%
swelling 3.4%

Reviews for Cetirizine

Commonly mentioned side effects
  • fru...
  • November 15, 2008

Cetirizine for Urticaria "I have had cholinergic urticaria for a few years now. I break out into hives when I start exerting myself physically or it's hot. After taking Zyrtec 1/2 an hour before my workout, I didn't experience that irritating itchy feeling all over, nor did I get hives. My skin got red, but no bumps. I don't care as long as I don't get the irritation, which works to create an aversion to exercise. I took a 5 mg dosage. After my workout, I went to sleep at 7 p.m., woke up for an hour, and then went to bed at 9 p.m., only to sleep the whole following day. I was unusually fatigued and sleepy. I'm going to try 2.5 mg today to see if that helps."

6 / 10
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41 Report
  • sme...
  • April 1, 2010

Cetirizine for Allergic Rhinitis "Zyrtec is the only medicine that controls my allergy symptoms, but it makes me so tired, sleepy, and I always seem to be 'zoning out.' I even passed a red light at an intersection a few days ago... thankfully, no one was hurt."

9 / 10
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30 Report
  • Pat...
  • June 23, 2019

For Allergic Rhinitis "I agree with the comments about making you drowsy and sleepy. Seemed to be okay with half a tablet, but as soon as I started taking a full tablet as the high grass pollen season approached, it left me a complete mess. Sleeping for 9 hours a night with 2-hour naps in the day. At work, I had to have power naps in the bog so I wouldn’t collapse at my desk. My brain was foggy, and it drains and sucks the life out of you to a point that I almost felt depressed."

3 / 10
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11 Report

Frequently asked questions

  • Anonymous
  • June 11, 2008

Cetirizine for Allergic Rhinitis "I have had side effects with every single allergy drug I've tried-prescription and none-ranging from sleepy to practically comatose. Zyrtec is the only medicine that helps me and positively impacts my quality of life."

10 / 10
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21 Report
  • hol...
  • April 24, 2016

For Allergic Rhinitis "Started taking this medicine for itching after being given it by my doctor. Worked for 1 day and after it didn't. Made me feel so sleepy but couldn't sleep and made my itching worse, couldn't sleep at night. Wouldn't recommend."

2 / 10
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6 Report

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  • Lau...
  • January 13, 2018

Cetirizine for Allergic Rhinitis "I used Zyrtec D for some really bad sinus pressure. It makes you sleepy during the day and anxious at night, but it has a very strong decongestant, and it works. I would never consider using it for a chronic condition because the side effects are pretty heavy, but if you're just using it for a few days to help while you kick something, it works great."

9 / 10
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5 Report
  • nen...
  • Taken for less than 1 month
  • March 18, 2016

For Urticaria "I went in to the doctor's because I have a rash all over my body, and he prescribed cetirizine. All it did was make me sleepy, the rash got worse. Then a different doctor looked at me three weeks later and determined I had scabies. Cetirizine really messed up my schedule. Being a college student, I fell behind because I was not able to keep up with homework."

3 / 10
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8 Report

More FAQ

  • And...
  • Taken for 5 to 10 years
  • November 9, 2019

For Allergic Rhinitis "I used to take one to two cetirizine every day at my old jobs. Two made me sleepy. I work in a moldy old building and a 100-year-old boat. I get 14 tablets for $1.00 at Dollar Tree or 400 tablets for $16 plus tax at Sam's Club."

8 / 10
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3 Report
  • San...
  • June 5, 2015

Cetirizine for Allergic Rhinitis "Zyrtec made me so sleepy I could barely perform my job. Also felt sluggish and dangerous while driving. All I could think of all day was 'I need to go to sleep.'"

2 / 10
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49 Report
  • Anonymous
  • September 23, 2008

Cetirizine for Urticaria "It works great for the symptoms of my allergies and hay fever. It does make me extremely sleepy, though. But, I suppose that is better than having a pounding headache or a sneezing/coughing attack."

9 / 10
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43 Report
  • Anonymous
  • November 14, 2010

Cetirizine for Allergic Rhinitis "It works well, however, it made me as sleepy as Benadryl."

5 / 10
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16 Report
  • Din...
  • Taken for 1 to 2 years
  • June 18, 2023

For Allergic Rhinitis "Although it seems to help with my congestion and swelling, the itching is horrible, and I stay sleepy constantly."

3 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.