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Rocephin User Reviews & Ratings

Rocephin has an average rating of 8.6 out of 10 from a total of 128 reviews on Drugs.com. 84% of reviewers reported a positive experience, while 10% reported a negative experience.

Reviews for Rocephin

  • Rose...
  • Taken for less than 1 month
  • November 1, 2023

For Urinary Tract Infection "I came home from work with one of the worst UTIs. I went from having a small amount of blood in urine to straight blood and burning. I admit at the doctor's office, I was a little skeptical about getting the shot. This was the best decision I have ever made. Within thirty minutes, I was no longer urinating blood and no pain. I still had a small amount only when wiping, barely noticeable. By morning, it was gone. Why has nobody ever recommended this before? I can't praise it enough. If you get really bad UTIs that happen fast and are painful, talk to your doctor about this medication. I did have to take another antibiotic with it, but the instant relief was so worth it. Yes, the injection spot is a little touchy for a day or two, but nothing like the pain from the UTI."

10 / 10
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27 Report
  • Anonymous
  • January 9, 2012

For Urinary Tract Infection "Received Rocephin injection in the left hip for a urinary tract infection. The injection itself was not any worse than any other I've received, but as the medicine starts making its way into the body, it becomes very uncomfortable. It feels very bruised and knotty at the injection site. However, I know this medicine works very well for this condition as I've had this twice previously, otherwise, I would not put myself through the discomfort. It is only painful from about 2-3 minutes following the injection up to about 30 minutes following when the pain wears down to barely noticeable except when the area is touched. It's highly worth the brief pain and discomfort. I always feel much better within 24 hours following the shot."

9 / 10
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144 Report
  • Chron...
  • Taken for less than 1 month
  • July 29, 2019

For Bacterial Infection "I had suffered from bacterial vaginosis for 3+ years. I constantly was treated with metronidazole (pills and gel), and it would immediately creep back within days of finishing my medicine. Finally, when I went to the ER with terrible pains in my abdomen, I was told I had PID. They treated me with a shot of Rocephin, and I haven’t had BV in over a year. It’s a miracle. Doctors should be treating patients with this instead of Flagyl/metronidazole. That doesn’t work! This shot kills it once and for all."

10 / 10
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66 Report

Frequently asked questions

  • BityBom
  • April 14, 2016

For Urinary Tract Infection "42-year-old female. 1 month ago, I went to urgent care for a UTI. I was given Cipro. The burning never went away. I finished all the antibiotics and saw my gynecologist. I had another urine test along with a Pap smear. All were normal. This entire week, I felt bad - extremely tired, shaky, weak, irritable, and of course, the burning that never stopped. I went to urgent care tonight. I saw a young male physician's assistant. He suggested a Rocephin shot. It hurt like heck, but 3 hours after the shot, it's like I'm healed instantly. My whole body feels 100% better. I think the burning is finally gone. I hope I feel this great tomorrow. It's been one miserable month."

10 / 10
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86 Report
  • bette...
  • January 10, 2010

For Urinary Tract Infection "Was given this after ER visit with severe testicular, urethra, and kidney pain. Tests for STDs were negative (ER did this anyway), so only conclusion was very bad UTI. Medicine (shot in buttocks) cleared up the problem within 72 hrs, even though azithromycin (1 g dose) given for bronchitis one week earlier did not."

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96 Report

Are you taking this medicine?

  • being...
  • Taken for less than 1 month
  • May 27, 2015

For Urinary Tract Infection "I've gotten UTIs twice a year for over a decade. Azo doesn't even take a little of the pain away... mine are always terrible! UTI hit me hard yesterday, and I went to the clinic. I asked for this shot based on people on the Internet saying it helped so fast. It's true. The shot hurts, but nothing is worse than the pain of the UTI. I felt better within hours. It's usually a couple of days before I get to feeling better using antibiotic pills, so I definitely recommend the shot!!"

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63 Report
  • Mandy
  • Taken for less than 1 month
  • April 29, 2020

For Bacterial Infection "I had my first sinus infection this year. I suffered from continuous low-grade fevers, headaches, sore throat, ears, and sinuses aching, and lymph nodes all swollen for weeks. Finally went to urgent care. I was given Augmentin for 10 days with absolutely no improvement. I went back and was given a shot of Rocephin and Toradol. Within 2 days, almost 100% back to normal. Also started 7 days of Levaquin. Unfortunately, the infection came back within 2 weeks. I got another shot of Rocephin today and within hours have started feeling better. It only burns a little. I did not have any side effects either time. Completely worth it!!!"

9 / 10
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35 Report
  • kwaggs
  • January 21, 2017

For Urinary Tract Infection "Had a severe UTI that didn't respond to Macrobid or Ceftin. My doctor ordered a shot of Rocephin, this is a miracle drug! The horrible pain I've had for over a week was gone in a few hours. I would definitely recommend this and would take it again even though the injection was a little painful!"

10 / 10
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50 Report
  • Dibur...
  • Taken for less than 1 month
  • December 22, 2014

For Urinary Tract Infection "10 weeks pregnant and found out I had a bladder infection/urinary tract infection. Doctor first prescribed Macro. Those were the worst 3 days ever. I could not stop throwing up. The smell of food made me nauseous. I was weak and did not move from the bed for 3 days, which is not like me at all. I am a very active person. I called the on-call doctor on Sunday night, and she told me to stop taking Macro and to come in tomorrow to get the Rocephin shot. I have to say just from one day of being off Macro, I already feel better but not 100%. I took the Rocephin shot and started to feel better little by little after 3 hours. I expected for the shot to hurt a lot. However, it only burned a little for a short period of time."

9 / 10
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54 Report
  • Brenda...
  • Taken for less than 1 month
  • March 30, 2013

For Pneumonia "Sick for 4 weeks, went to the doctor. Ear infection, sinus infection, and bronchitis prescriptions of Augmentin and Mucinex. Since 6 months earlier, I had pneumonia that took me out of work for short-term disability. When I heard the telltale 'rattling' on my left side 8 days later, I went back to the doctor. So after 5 weeks of coughing, sneezing, headaches, and overwhelming tiredness, I received a shot of this. I had not had a shot of anything for many years, and it did hurt. I am not a wimpy, owy person. It did hurt. It hurt for 45 minutes. But the next morning, I woke without coughing up a lung, rested, and feeling better than I had for a month. The second day (now), I am headed out to cut the grass after vacuuming the house. Yeah."

9 / 10
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59 Report
  • Preggo
  • Taken for less than 1 month
  • October 19, 2014

For Urinary Tract Infection "Thank God for this shot! Doc had me on cephalexin, which only made it worse, and then Macrobid, which made me deathly sick. I couldn't take it anymore since I was pregnant and already miserable! OB gave me this shot in my right hip, and I couldn't feel better. Turns out I don't have any pregnancy symptoms, it was the urinary tract infection making me feel so awful! I felt better an hour after the shot and have been actually able to eat more than two bites of food since! Worth the burn and soreness afterwards."

10 / 10
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53 Report
  • worry...
  • Taken for less than 1 month
  • December 13, 2016

For Bacterial Infection "my husband was given a shot of rocephine within seconds he was in anaphylactic shock. He was given benedryll to reverse the medication. He was rushed to the hospital his blood pressure shot thru the roof he nearly died. From the shot he suffers from serum sickness, high blood pressure, irreg heart beat, extreme sweating, restless leg sydrom,, headaches, loss of appetite, PTSD, extreme panick attacks, hyperactivity, insomnia, flushing, jitters all the time, fear, depression, chest pain, feeling of discomfort. Loss of dignity, my husband is a different person and this drug did this to him. It is a daily struggle every moments to keep positive and hope for a cure to fix his neurological damage this shot has caused"

1 / 10
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44 Report
  • Amy
  • September 30, 2019

For Urinary Tract Infection "Second time posting, hoping it might help someone. Had symptoms of a UTI on Friday. Not happy all weekend. Got into the doctor this morning and had a shot. I still hate getting two shots in my bottom, but my doctor also insists on giving me a B12 shot when I see him because I am slightly anemic. I am not sure if it is because I am skinny, but Rocephin burns like heck and I am almost in tears getting it. Maybe I am just a wimp, but I don’t like needles getting stuck in me, and Rocephin is the worst! It is now around 3:00, and I have no symptoms. It works, and even though I dreaded the shot all weekend, I am glad I got it."

9 / 10
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30 Report
  • Apolk
  • Taken for less than 1 month
  • December 30, 2016

For Urinary Tract Infection "Because of chronic UTIs in my past, I had developed resistance to almost all antibiotics for treatment, including Cipro, Bactrim, Amoxicillin, and Macrobid. Either they made me sick with flu-like aches and pains or just did not cure the infection. The Rocephin shot was prescribed and done last time in the doctor's office, I felt better within hours. I have to say, until tonight, it had been 8 months since my last UTI. That is definitely a record for me! Given the shot again today, hoping for the same results..."

8 / 10
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40 Report
  • Lynne
  • June 16, 2018

For Urinary Tract Infection "Recurrent UTI and bladder infections. Last year, needed hospitalization, turning to sepsis. Three days of IV Rocephin and ten months later, another UTI and after a shot of Rocephin, started clearing up the symptoms immediately! Oral antibiotics never work! This is a miracle drug for this condition, with no side effects for me!"

10 / 10
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32 Report
  • gjubl
  • August 23, 2016

For Urinary Tract Infection "Have been in agony with UTI after UTI, burning and sick and debilitated, and no other antibiotics touched it. Had a positive strep B culture. Finally, feel relief after Rocephin injection. It also helped before quickly with a sinus infection. Highly recommend. Antibiotics are awful with deadly side effects. Ciprofloxacin and Levaquin can kill you. Research those two on side effects."

10 / 10
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38 Report
  • CindyK
  • Taken for less than 1 month
  • April 6, 2016

For Urinary Tract Infection "Given one shot of Rocephin (IM, dorsogluteal) for severe UTI. Shot a little painful, but experienced relief of abdominal discomfort within about 30 minutes. Some bruising, but definitely worth it for the quick relief."

10 / 10
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39 Report
  • Feeling...
  • September 9, 2018

For Urinary Tract Infection "I have been getting UTIs for many years. Usually take Bactrim or Cipro. Had such a bad one, plus pain in my back, and I felt like the Bactrim was making me feel awful too. I ended up going to the ER because I have only 1 kidney and can’t allow a kidney infection to set in. I got a Rocephin IV, and it is now 9 hrs later, and I feel so much better! It's still soon to say it completely cured it, but I am actually having real relief for the first time in 5 days. Why didn’t I ever hear about this drug before?"

10 / 10
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30 Report
  • Relie...
  • January 26, 2017

For Urinary Tract Infection "My 11-year-old had a 102 temp for 2 days, achy all over. Day 3, 104. Went to the clinic. Negative for flu and strep and white count normal. Advised to push fluids and treat fever. Day 4, temp 105. Went back to the clinic. Urinalysis shows raging UTI and now she's really dehydrated. Had 2 options: shot of Rocephin, push fluids, and start oral antibiotics, but if not better by morning she'd be admitted to the hospital. Or just admit her right then. We went with the shot. Within an hour, I saw vast improvements. Fever has not been above 100.5, pain is better, drinking better, and even managed to eat a little bit and work on 4 days of homework! Would definitely recommend Rocephin!"

10 / 10
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35 Report
  • Sherry
  • July 3, 2018

For Urinary Tract Infection "Had UTI diagnosed over a month ago, given Cipro. Never felt quite over the UTI. Ended up getting Bactrim, UTI started raging again. Went back to doc and requested Rocephin. Received shot and was 99% better within hours. Seeing my own PCP in 2 days, may get another shot. I'm working away from home and I found out I’m resistant to many antibiotics now, so Rocephin saved me from permanent kidney damage :)"

10 / 10
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28 Report
  • Shanna
  • January 5, 2012

For Pneumonia "I've been sick with what I thought was just a cold for the last 3 weeks, and finally my cough got so bad the other day that it hurt in my back every time I coughed or took a deep breath. I went to the urgent care clinic and found out I have walking pneumonia. They gave me a shot of Rocephin and Dexatron. It didn't even take 30 mins for it to begin working on my breathing and my lungs. I was already feeling halfway better when I left the doctor's office, and when I woke up today, I feel almost back to normal. With the exception of my right buttock being a little tender from the shots, and I have a little leg pain. I am so thankful for this shot. I have been in misery for the last 3 weeks, and it took less than 24 hours for this medicine to start healing."

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47 Report
  • Skky
  • Taken for less than 1 month
  • August 3, 2020

For Urinary Tract Infection "This is my 3rd UTI in an annual year. One in Oct of 2019, May 2020 and Aug 2020. I woke up at 2 am 2 days ago feeling that all so familiar feeling. By 1pm Sunday I headed to the ER. I started urinating blood, passing clots and my pelvic area was killing me! A UTI causes INTENSE pain, I would birth my 4 children all over again! Doc did a phone call appt (due to covid) today and he said I am perimenopausal(sp) at 38 years old :/. My estrogen is funky so that could def be a culprit. I did have the rocephin shot last night, but it's taking a bit longer to COMPLETELY go away vs the last 2x. I am TERRIFIED of getting another UTI. My doc suggested a natural supplement call de mannose. Anyone taking this? I have to order it, drug store was out. Apparently it's a preventative supplement for UTI's. All I know is that the pain of a UTI is forever traumatizing! The shot hurts, yes, but SO worth the relief. I would recommend it to anyone."

10 / 10
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20 Report
  • Number
  • October 18, 2013

For Pneumonia "Had a 102-degree temp for 4 days, 101 degrees for 4 days. Felt like I was coughing up my lungs and could not catch my breath. Sounded like a gurgling sound in my lungs all the time. Was the worst I ever felt. Went to the doctor and got a shot, and within 6 hours, I was ready to go cut the grass."

10 / 10
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41 Report
  • Quiet...
  • Taken for less than 1 month
  • August 19, 2016

For Bacterial Infection "I've had a persistent UTI and been through 2 rounds of oral antibiotics, and it kept coming back despite having had a culture done to determine what would be effective. Once the pain got bad enough that the pyridium was no longer effective, I called the doctor and begged for help while still waiting for the second culture results. They gave me a shot of Rocephin. By morning, I felt 85% better. The second day, I still feel a twinge of symptoms here and there, but feel soooo much better. The shot hurts, yes. But it's not THAT bad, and there was lidocaine in my injection to help with that. Powerful stuff - so glad they gave it to me!"

10 / 10
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31 Report
  • Uncle...
  • Taken for less than 1 month
  • December 22, 2013

For Pneumonia "I'm a healthy 71-year-old male with one weakness - my lungs. I've had bronchitis as a boy and had pneumonia twice before, and this is the third time getting pneumonia. The Rocephin was added to a slow intravenous drip. Good relief the first day, and today, the second day of treatment, I got my appetite back. I have one more day of intravenous, and I think I may be back to near normal."

10 / 10
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37 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.