Skip to main content

Cariprazine and Weight Gain: What Users Say (Page 3)

Brand names: Vraylar

Reviews for Cariprazine

Commonly mentioned side effects
  • Dal...
  • Taken for 1 to 6 months
  • September 3, 2021

Cariprazine for Bipolar Disorder "I’ve been on Vraylar for about 6 weeks, and I’ve definitely noticed a difference. I started with 1.5 mg, then increased to 3 mg about two weeks ago. Not really any side effects that I’ve noticed-maybe slight weight gain, unfortunately. I’ve been on medications for Bipolar II that have made me feel like I was absolutely losing my mind, so Vraylar is a nice change. I take Vraylar along with 100 mg of Seroquel. I’d recommend this medication for Bipolar II."

9 / 10
Was this helpful?YesNo
3 Report
  • Mid...
  • Taken for 1 to 6 months
  • January 5, 2018

Cariprazine for Bipolar Disorder "I started taking Vraylar on July 17. I suffer from major depression, OCD, panic disorder, and generalized anxiety disorder. I felt emotionally regulated. However, I gained weight and experienced insomnia, which was already an issue for most of my life. I stopped the drug twice. My mood deteriorated and became more unregulated. I've been back on for 4 weeks. My mood has stabilized. The weight gain has been an atrocious side effect for me. I'm very petite, and gaining 12 lbs has been very physically uncomfortable. I eat well and am always on the move. I've also suffered from chronic diarrhea; however, I have IBS. I do feel the constant diarrhea that is now occurring is related to Vraylar."

6 / 10
Was this helpful?YesNo
8 Report
  • GMo...
  • Taken for 1 to 2 years
  • June 11, 2024

For Bipolar Disorder "I had a meeting with my doctor yesterday after 3 months. Same meds to continue except Fludac 20 mg to be taken now on alternate days instead of taking it daily. So currently I am taking 3 mg Cariprazine daily. In addition to this, I am taking Fludac 20mg, Licab 300mg twice daily, Quetiapine 7.5 mg once daily, and Mirtaz 50mg once daily. No more depression, suicidal thoughts, mania, manic episodes, or anxiety. I am lucky as Cariprazine is working well for me. I have gained a lot of weight, which is okay. Next meeting in September 2024."

8 / 10
Was this helpful?YesNo
1 Report

Frequently asked questions

  • Bas...
  • Taken for 1 to 2 years
  • July 28, 2021

Cariprazine for Bipolar Disorder "2nd time on Vraylar. 1st time it saved my life. Doc took me off it despite it working wonderfully, due to weight gain. I have been on everything but nothing seems to work. I also have severe anxiety and insomnia. I take 10 mg of Valium 3 x day for the anxiety, but when my doc took me off the Vraylar, it made my anxiety unbearable at times. So I would 'smoke' to help. Now back on Vraylar, back up to 6 mg, no real side effects. The anxiety is gone, but I find I only need about 4 hours of sleep a night, even though I'd love a full 8. I'm definitely more 'activated' too, but it beats the depression I sunk into when taken off the Vraylar."

10 / 10
Was this helpful?YesNo
2 Report
  • GMo...
  • Taken for 6 months to 1 year
  • June 17, 2023

For Bipolar Disorder "This is my second post. I am on the 7th month. So far, cariprazine is working fine. No depression, mania, suicidal thoughts, or anxiety. But GI problems. Not constipation, but incomplete evacuation, so I have to take laxatives. My doc told me to continue this med, 3 mg daily. I do hope it helps others. Follow-up visit with my psych next month. Other issue is weight gain, but I don't mind it."

9 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • GMo...
  • Taken for 1 to 6 months
  • June 8, 2023

For Bipolar Disorder "I have bipolar disorder. My doc tried various drugs but still was edgy, panicky, and depressed. Then he put me on cariprazine. This drug has taken off my edginess, panic attacks, and depression. I have a lot more energy, no anxiety. Started with 1.5 mg and now am on 3 mg. The downside is this drug is affecting my bowels, and I have developed irritable bowel syndrome. I also gained a lot of weight. But all in all, a positive experience."

8 / 10
Was this helpful?YesNo
1 Report
  • Ste...
  • Taken for 1 to 6 months
  • October 4, 2022

Cariprazine for Bipolar Disorder "I’ve been on this medication for 4 months, it has helped with my depression. I experienced what can best be described as cognitive delays or brain fog, which allows me to deal with my emotions before exploding. This makes it easier to get along with the people around me. Unfortunately, it makes it difficult for me to do my job. Additionally, I also noticed an increase in my appetite, which has resulted in weight gain."

8 / 10
Was this helpful?YesNo
1 Report

More FAQ

  • Lis...
  • Taken for less than 1 month
  • July 24, 2017

For Bipolar Disorder "This medication is wonderful for my Major Depressive Disorder. My Dr. prescribed it off-label to treat my depression because its cousin, Rexulti, also worked great for me but caused a 20 lb weight gain. So far, I haven't had weight gain, but it's too early to tell. It pretty much cured my depression (short-term at least). It feels like I can't get low, like there is a block stopping me from feeling sad. I have a ton of energy, I'm cleaning again, picking up new furniture, etc. I hope it continues to work so well. I started feeling the effects day one. PROTIP: take this at night because it causes crazy drowsiness for the first couple of hours."

9 / 10
Was this helpful?YesNo
2 Report
  • Mam...
  • Taken for 1 to 6 months
  • April 12, 2021

"This has been a terrible drug overall for me. I am taking it for depression and anxiety. I haven’t slept through the night in months. I’ve gained 20 pounds despite all efforts (and my ADHD meds) and have virtually come out of my skin every moment. The lack of sleep, weight gain, and terrible restlessness have been the hardest to deal with. I’m constantly hungry, anxious, and my shopping has been so impulsive. I’ve literally scared myself on this medicine. Never again!! My primary care doctor put me on this medicine to help with anxiety, but it caused more problems than I had before. I don’t think this should be prescribed unless by a psychiatrist and even then only as a last resort. This has been awful. I’ll take my anxiety, thanks. Now can I finally sleep, quit eating like crazy, have my foot muscles quit spasming, and actually get my libido back? Don’t take this unless nothing else works!!"

2 / 10
Was this helpful?YesNo
0 Report
  • Kri...
  • Taken for 1 to 6 months
  • April 25, 2025

Cariprazine for Major Depressive Disorder "I'm having second thoughts about continuing to take it even though I feel like it is helping with my depressive symptoms. I normally don't pay too much attention to possible side effects listed for medications because I don't want to overreact. Today, though, I read through them because I'm having some weird stuff going on medically, including problems with breathing, weight gain, cough, constant hoarse voice, muscle spasms almost daily, and sometimes multiple at once."

5 / 10
Was this helpful?YesNo
0 Report
  • Mis...
  • Taken for 6 months to 1 year
  • February 16, 2019

Cariprazine for Bipolar Disorder "I gained 67 pounds over the course of 10 months at 4.5 mg-just beware of weight gain."

1 / 10
Was this helpful?YesNo
41 Report
  • tds...
  • Taken for 1 to 2 years
  • November 9, 2024

Cariprazine for Major Depressive Disorder "Good med. Helped relieve my depression, and I felt good on it, but it caused weight gain/increased appetite. That was the main drawback. 1.5 mg to 3 mg. Added to other depression meds."

7 / 10
Was this helpful?YesNo
4 Report
  • Kat...
  • Taken for 1 to 6 months
  • September 4, 2019

Cariprazine for Bipolar Disorder "It's a great med, but I have put on almost 15 pounds on it."

6 / 10
Was this helpful?YesNo
22 Report
  • Dep...
  • Taken for less than 1 month
  • September 2, 2018

Cariprazine for Bipolar Disorder "Awesome. No more racing thoughts. Mania has slowed down, and no weight gain. However, I have samples. Don't know how I am going to afford it."

10 / 10
Was this helpful?YesNo
21 Report
  • Bip...
  • Taken for 6 months to 1 year
  • January 4, 2025

Cariprazine for Bipolar Disorder "Not good, gained a lot of weight! Uncontrollable eating! Only taking 3 mg."

6 / 10
Was this helpful?YesNo
1 Report
  • Tra...
  • Taken for 1 to 6 months
  • August 5, 2021

Cariprazine for Schizophrenia "I had very bad agitation, and this medicine did not do a thing for my psychosis, voices, racing thoughts, and things of that nature. Massive weight gain as well, risk everything for no reward."

1 / 10
Was this helpful?YesNo
6 Report
  • Kar...
  • Taken for 1 to 6 months
  • June 3, 2024

Cariprazine for Bipolar Disorder "Seem to be much better than Abilify as long as there is no weight gain."

9 / 10
Was this helpful?YesNo
2 Report
  • cha...
  • Taken for 1 to 6 months
  • May 31, 2023

Cariprazine for Bipolar Disorder "Vraylar did not help my bipolar symptoms at all and caused a massive weight gain."

2 / 10
Was this helpful?YesNo
2 Report
  • Inn...
  • January 10, 2022

Cariprazine for Bipolar Disorder "I like this medicine, but the weight gain is not fun. Every winter I gain 28 pounds I lose in summertime. It's mostly water weight."

9 / 10
Was this helpful?YesNo
2 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.