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Wellbutrin SR User Reviews & Ratings (Page 3)

Wellbutrin SR has an average rating of 7.1 out of 10 from a total of 130 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Wellbutrin SR

  • DW27
  • Taken for 1 to 6 months
  • September 26, 2012

For Depression "I am on bupropion SR for 2.5 months and it's been pretty good so far. I don't sleep all the time like on citalopram, and my weight stayed the same with a slightly diminished appetite. The depression is mostly gone even though I'm unemployed for a long time living off dwindling savings. But I'm actually trying to get work now since I have more energy and feel generally better than ever despite the economy. My libido isn't much despite other comments here. Some anxiety still there, and a few drinks in the evening help that. The biggest side effect is extreme sweating when it is humid and above 70 degrees. It's embarrassing. For me, bupropion (Wellbutrin SR) 100mg twice a day mostly works. Good luck."

8 / 10
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  • Itll...
  • Taken for 6 months to 1 year
  • July 1, 2015

For Depression "I've been on Wellbutrin SR 150 mg for depression and anxiety. I was very hesitant to try another medication after negative experiences with other meds. I knew, however, that I needed more help than therapy alone, so I decided to give WB a try. Initially, I had some insomnia, nausea, headaches, and severe light sensitivity. However, these effects passed and were mild compared to how much better I felt. Within 4 weeks, I had more energy, felt less anxious, and the depression started to lift. I felt focused, peaceful, and content. All was well until about two months ago when some anxiety resurfaced (exams). The doctor tried to increase the dosage, but the side effects were terrible. So I remain on 150 mg, but still feel much better than my pre-WB days."

7 / 10
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  • RCs...
  • January 20, 2013

For Depression "False-positive urine immunoassay screening tests for amphetamines have been reported in patients taking bupropion (the active ingredient contained in Wellbutrin SR). This happened to me with the birth of our second child. Our daughter tested positive for amphetamines. Child Services were called, and we had to prove our own innocence! The nurse reporting the 'problem' told us that they knew that Wellbutrin SR could cause this result, but according to the law, we were still reported."

8 / 10
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70 Report

Frequently asked questions

  • yeste...
  • Taken for 1 to 6 months
  • June 7, 2015

For Depression "I started at 100 mg, and the first few weeks I felt really amazing for the first time in my life. After the fourth week or so, I switched to the 150 mg because I had found that the initial euphoria had worn off, and I thought that it had lost its efficacy. The higher dose was too strong for me, so I switched back and have been on the 100 mg since. I do not have the same dark cycles that I used to, and though I still feel depressed at times, it is not nearly as often as before, and the episodes are manageable. I am not feeling chronic hopelessness nor paranoid or defensive. It does not feel like I am 'medicated' while on this. I am not experiencing many side effects (just more intense dreams and some minor constipation)."

9 / 10
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  • SAM
  • Taken for 1 to 6 months
  • December 5, 2016

For Depression "I took this 75 mg for about 5 months. I loved how it got me up and going compared to the 20 mg of Prozac I was taking off and on 9 years before. But around the 4th month, I started finding myself getting mad easy, and then my 1st panic attack happened. I had never known about this and wish I never did. I stopped the Wellbutrin 6 months ago, and I'm still having horrible attacks that keep sending me to the hospital. The ER doctor told me I'm not the first to say their panic attacks started after taking Wellbutrin. So I'm standing up to ask if anyone else has, because it's not in their side effect list."

3 / 10
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Are you taking this medicine?

  • partr...
  • Taken for 1 to 2 years
  • May 29, 2020

For Depression "I was prescribed Wellbutrin SR as a boost for my regular antidepressant (I have seasonal affective disorder), since I am at the top end of the dosing and didn't feel comfortable increasing. Overall, excellent medication. I don't notice many side effects, and it has helped to increase my energy/mood enough to make it bearable during the winter months. If I miss a dose, I get a headache, which does grow into a migraine if left unchecked."

8 / 10
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  • Sean_c
  • January 22, 2017

For Depression "I stopped taking Effexor after being on it for five years. Worked great, but it was keeping me up at night, had to skip a dose to have a decent sleep. So I reduced to the lowest dosage before completely going off with the help of my doctor, in the hopes I didn't need antidepressants anymore. Was okay for a few weeks and boom, super depressed, suicidal, the works. So I was prescribed Wellbutrin and mirtazapine for sleep. The Wellbutrin worked right away, and mirtazapine was great for sleep. But it only worked well for a few months. Started redeveloping social anxiety, panic attacks, fits of rage, suicidal thoughts, and all that fun stuff. I went to a new doctor, and he basically told me that Wellbutrin isn't good for anxiety, lol. Good to know!"

3 / 10
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48 Report

More FAQ

  • Gpc
  • Taken for less than 1 month
  • October 31, 2021

For Depression "I've only been on it for three days, first day I had more energy than I've had In a while ..second day I felt horrible and today 3rd day ..when I woke up I felt horrible but as the day has went on its kinda gotten better. Don't know how well it's gonna work but have my fingers crossed. Anybody reading this "never give up" "failure is not an option."."keep fighting" You will succeed. This too shall pass..give it all to God and he will help you . I PROMISE THAT."

7 / 10
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23 Report
  • sun
  • May 24, 2017

For Depression "The Wellbutrin XL gave me severe constipation and headaches, but the SR is working well. I have only been on it for 2 weeks and I notice an improvement in my moods, daily sleepiness, and it has NOT decreased my sex drive. Prozac worked well for me also, but it just killed the sex drive, and at my age, that wasn't acceptable. (38). I feel myself eating less, and hopefully, it may lead to a few pounds weight loss."

8 / 10
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  • Ronal...
  • Taken for 2 to 5 years
  • May 2, 2017

For Depression "This medicine has been the best at treating my depression. I've tried Prozac, Pristiq, Effexor, and Trintellix, and Wellbutrin's stimulating properties are what have made this drug so effective for me. Every other antidepressant I've been on has made me feel drugged, zoned out, and tired. Probably the best out of all the other antidepressants I tried was Effexor, but even then, it triggered what I now believe to have been manic episodes. The sad thing is that this drug is no longer effective for me after 3 years."

9 / 10
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  • Steph...
  • Taken for 2 to 5 years
  • December 5, 2014

For Major Depressive Disorder "I started this medication at a time when I did not have any health insurance and had to pay around $40/month for it. One of the very first things I noticed when taking this medication was that I started smoking fewer cigarettes; it made the cigarettes taste the way they should, horrible. I never had any other side effects from the medication. When I switched to another medication, it became very apparent that I was not doing as well as I had been while on the Wellbutrin SR, so I switched back after a few months and a couple of different meds. This is definitely my favorite; I'd been on several different medications for my MDD and always had terrible side effects. Not with this!"

9 / 10
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  • Koala...
  • Taken for 1 to 6 months
  • November 9, 2014

For Major Depressive Disorder "I was skeptical about bupropion. I started this at 150 mg. I am bipolar and must say that it has been a Godsend. I read up on it and how it can give you energy plus can also help with concentration, I scoffed in a way. No longer do I scoff. I am so grateful that I take this, it does not affect any SSRIs as it's differently made up. I am on Zoloft and bupropion, these do not cause me a problem. It is possible to take these with bipolar, yes, there is research regarding antidepressants and bipolar, but for me, it has given me back my life - I do have energy to leave the house, I can concentrate, my memory is better, but I now have a life - a social life. I go out. So please don't be scared off by antidepressants and bipolar - ask the question."

9 / 10
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  • KAEST
  • Taken for less than 1 month
  • March 11, 2015

For Major Depressive Disorder "I've been on Wellbutrin XL for a few years and recently was switched to Wellbutrin SR. I felt an immediate difference. I was dizzy the first day, but the 2nd day I was alert and calm. I've lost 10 pounds in the few weeks I've been on it, which is good going from 150-140."

9 / 10
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  • tenne...
  • Taken for less than 1 month
  • August 28, 2020

For Depression "I started Wellbutrin XL 150mg (once a day) for about three weeks, Depression and ADHD, it fixed the ADHD but it caused me to cry every single day and to have more intrusive thoughts. I called my DR and he switched me to Wellbutrin SR 100mg (twice a day), todays day 1 of taking the SR, hopefully its works... to be continued."

8 / 10
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27 Report
  • Sonya
  • Taken for 1 to 2 years
  • November 14, 2020

For Depression "Wellbutrin 150sr 2x daily was prescribed for me for Severe anxiety and mild depression. This medication is great for energy but I am so short tempered and I get negative intrusive thoughts. I like the energy it gives me and I don’t feel spaced out like on some antidepressants but I’m debating going back on Effexor 75 mg. It is better for anxiety and irritability. I’ve gained 10 lbs but I think it’s from the Covid lockdown stress eating so I won’t blame it on the Wellbutrin. I would recommend Wellbutrin for people with lethargy but not with anxiety disorders."

10 / 10
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  • Femal...
  • Taken for 10 years or more
  • December 24, 2016

For Depression "I credit Wellbutrin for my life. Started taking 150 mg Wellbutrin SR 15 years ago to combat the sleepy side effect of Prozac (taken for depression). About a year later, I dropped the Prozac (because of sexual side effects). The Wellbutrin is enough to keep me normal. Over the 14 years, I have tried 1: The no-name brand (almost a disaster - made me sleepy & more depressed - fortunately, I figured it out before getting suicidal) 2: The name brand long-acting version - again made me sleepy and more depressed. 3: Took 2 by accident once or twice - okay until it wears off, then withdrawal feeling/depressed. 4: Sometimes I take one in the afternoon (when I am unemployed and more depressed), this works pretty well provided I take it before 3 PM - or it keeps me awake."

10 / 10
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  • Cassa...
  • Taken for 1 to 6 months
  • July 18, 2019

For Depression "I took 100mg for one month and it really helped with hormonal migraines that I suffer from daily. Cramps and body aches were gone. Worry about the PMDD gone. Depression -gone. I had a lot more energy! I really was soo happy until I realized that my face HURT with raw deep acne lesions. My forehead was completely covered (never happened before in my life) as was the rest of my face (usually only on chin and jaw areas at PMS time). I did experience bad ringing in my ears for the first 3 weeks and it was tougher getting to sleep. I could handle all that but not the pizza face. Too bad:( I also experienced hair thinning but that could be from PMDD. I'm not waiting it out and letting my skin continue to scar."

7 / 10
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28 Report
  • kendrah
  • December 26, 2015

For Major Depressive Disorder "I took Zoloft for anxiety and depression. Helped with anxiety but didn't touch the depression. So I started taking Wellbutrin SR, and now I'm at 150 mg altogether per day. I'm glad because I don't think about suicide, but I can't be fully happy and hopeful yet. Getting there, though."

8 / 10
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40 Report
  • CMano
  • September 8, 2021

For Depression "I have been on Wellbutrin SR since it was first introduced in the 1980’s. I had been diagnosed with major depression. It stopped ALL signs of depression for me. I am on this medication today. I had tried all of the medications that were on the market for depression with no success. This was a game changer for me as I am now a Registered Nurse."

10 / 10
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  • Tori
  • October 11, 2016

For Depression "I started taking this medication last week. I started suffering from depression when my marriage began to fall apart! I was trying for years to be there for my husband as he returned from a deployment suffering from severe PTSD! Right now I can say my opinion on this medication differs. One day I'm fine and can get through my day calm, other days I have severe anxiety and I'm freaking out, or I'm so tired with headaches that I just want to be alone and sleep all day! A big concern, even though I shouldn't be complaining about, is losing weight. In a week I have already dropped 5 pounds! I feel as if I should give this more time to balance me out! I'm only on 150 mg once a day."

3 / 10
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  • Steve...
  • July 31, 2015

For Depression "Was having some anxiety and depression issues due to many life factors. Was told that Wellbutrin would be a good option and that it was fairly mild. The first few days had the euphoric feeling everyone talks about, but this ended in 2-3 days. After that, anger kicked in to the point where I was taking walks at 1 a.m. to calm down and relax. From there, the weirdness kicked in. A feeling that's hard to describe, but life got very flat. Didn't feel anything, just flat. I felt like I had a lobotomy or something. At a party last week, a friend asked if I was stoned as I looked out of it. Then I forgot to take it one day, and I felt great that day-joy, emotions, had fun. I then took it the next day and felt horrible. Cold turkey and happy, not for me."

3 / 10
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  • byn
  • January 16, 2018

For Depression "Took me 2 tries to get on it. The first time I tried it, it sent me into an anxiety attack for 3 days, and I had to stop. I think this was my own nerves, though. Waited a couple of months, then tried again. This time it went much better. The first 4 days had a lot of head fogginess and jitters, but otherwise not too bad. After that, suddenly I felt much better! My mood improved a bit, I had much more energy (I wasn't getting that mid-day crash anymore), and I was getting fewer headaches. But the cons of it were constipation, mild moodiness, and anxiety in the evening and towards going to sleep for some reason. Not a terrible experience, but ended up being a bit too much for me to handle as a full-time student."

8 / 10
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  • Cat
  • Taken for 1 to 6 months
  • October 30, 2018

"I'm a teenage girl living with depression, anxiety and sensory processing disorder. Previous to wellbutrin, I was taking abilify for close to 5 years. I gained over 120 pounds on abilify within that time, and kept growing until I switched to wellbutrin. One thing I found detrimental was that even though abilify made me happy, I still had trouble with SPD (Sensory processing disorder) , anxiety and weight gain, which was in it's own way, making me worse mentally. So far it's been about a month and I've lost almost 10 kilos. 2 in the first week! I don't have the obsessive eating I had with abilify, nor do most of my SPD triggers bother me as much anymore. It's amazing. I wish I knew about it sooner."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 30, 2014

For Depression "I felt it working in a couple of days, and I felt great! The depression lifted, and I felt so much more energy, no more crying, and actually wanted to do things! There is depression that runs in my family, and I also feel like it happens more seasonally in the winter. However, after a week of taking it, I developed an allergic reaction and broke out in hives on my legs. This is the first allergy I've ever had! Had to stop taking it due to the reaction, and now I've been put on Pristiq... we will see how things go."

3 / 10
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  • Kuros...
  • October 4, 2009

For Depression "I'm on my 5th day of Bupropion for generalized anxiety and depression, and so far, very happy. Appetite is way down (food drive was through the roof before), and although sex drive has not changed, the degree of pleasure is up. I had a feeling of lightheadedness for the first two days before it subsided. The only real side effect is a mild case of localized dystonia at the base of my neck. I have had such a positive experience so far with the drug (compared to the many side effects of other medications) that I think I can live with a little discomfort and rigidity for now."

9 / 10
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54 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.