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Bupropion for Depression User Reviews (Page 4)

Brand names: Wellbutrin XL, Wellbutrin SR, Forfivo XL, Aplenzin Budeprion Budeprion SR

Reviews for Bupropion

Commonly mentioned side effects
  • Anonymous
  • Taken for 1 to 6 months
  • January 8, 2015

Bupropion "Wellbutrin SR 150s, which initially had positive outcomes on my depression, probably the best I've tried, and I've tried a lot in the past years. It took a bit to get the optimal dose. At 300 mg, it was causing a cascade of side effects: anxiety, palpitations, sweating. Doc helped me back down to 100 mg with no side effects. The depression is just as gone as with the initial 300 mg. Wellbutrin also developed a positive outcome in mere days - a major plus."

8 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • July 26, 2023

Bupropion "At week 3 of taking Wellbutrin, I got a serious serotonin rush that lasted only 1 day (it was fabulous) and by week 4, I had superpower concentration. My work was getting done faster, and I was clearheaded. But by month 2, it all went away. I am starting month 4 and I am unable to concentrate again, I am crying, I feel 'down'. I feel exactly the same as before I started. I don't want to go on a higher dose because, where does it end? For me, I'd have to say it didn't work."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • April 29, 2016

Bupropion "26-year-old male. Been on it for 31 days. 1st week 150mg XL: high-speed energy. Mild insomnia (up till 3 am most nights). Waking early and generally good mood. 2nd week 300mg XL. Very high constant anxiety. Emotional swings. Broke down in tears one day. 3rd week: Things were smoothing out. Still slightly anxious. Less emotional. 4th week: Feeling completely normal, almost like I'm not on any medication. More level-headed and better mood with fewer swings. Anxiety disappearing and confidence growing. No side effects. This is in combination with seeking help from a counselor, and confiding with a close friend of mine about how depressed I have been over the years. I am happy I took it. It has got me back on my feet and allowed me to seek help."

8 / 10
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Frequently asked questions

  • Mam...
  • Taken for less than 1 month
  • March 1, 2014

Bupropion "This medicine has saved my life. I was on it for several years (300 mg) and felt it wasn't helping anymore, so I quit it on my own. No problem quitting, but a few months ago began feeling hopeless due to financial problems and could not do anything on weekends but lay around in bed and sleep my weekends away. I couldn't get anything done and put important things off that needed to be done. In just the last 2 days, I can tell that I already want to get out of bed and do housework and get a shower. I didn't realize what Wellbutrin XL did for me, but I do now and am grateful I am back on it!"

10 / 10
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  • She...
  • Taken for 5 to 10 years
  • January 18, 2013

Bupropion "I have been on Wellbutrin XL now for almost 7 years and I love it. Before starting Wellbutrin with the other medications, I felt tired, could hardly function, and could not think clearly. It was so bad that I was ready to quit all the meds and just live my life depressed. I mean, after all, I was sleeping my life away anyway so it didn't matter. So I told my psychiatrist and she put me on Wellbutrin XL. It took about 3 weeks to start noticing a big improvement. I felt energetic, I wanted to do things again, my mood has been really good, I could concentrate. It helped me tremendously in my job and I was able to start living life to the fullest and be that fun-loving, energetic person I want to be. I highly recommend this medicine."

10 / 10
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  • you...
  • April 17, 2019

Bupropion "After a few bouts of mild depression, I entered a more major depressive period about two years ago. I told my psychiatrist I was so sad 'my teeth hurt'. I was unmotivated, hopeless, and really just sooo sad all the time. My doctor tried to give me an SSRI but I pushed for Wellbutrin due to the lack of sexual side effects and weight gain with SSRIs. The first couple of weeks on it, I was on a total high. I remember dancing around with my kids and literally jumping around at the playground like a crazy lady. Once that levelled off I was just 'me' again. No other way to put it than I feel totally normal now. I still get sad, happy, angry (so I'm not flat) but all within a normal range. The ONLY negative for me is that if I miss a dose I turn into a raging crazy lady. I feel like I'm withdrawing from hard drugs. It definitely makes me scared of when the time comes to try and get off of it, but for now it's worth it."

9 / 10
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  • Fai...
  • Taken for less than 1 month
  • November 27, 2021

Bupropion "I am on week 3 on Bupropion 150 SR, I went off Paroxetine cold turkey and started this. First week, I was tired all the time and had some weird nightmares that went away starting the 2nd week. Then the 2nd week, I felt awkward. I was not myself, I was very irritable, didn't want to be around people, had some headaches that week, and wasn't interested in doing many things. I was about to quit, but my doctor told me to please give it a try until week three when it is supposed to start working (from week 3 to 6). So I did with a lot of effort, and I am so HAPPY I DID HANG IN THERE!! I FEEL SO MUCH BETTER. Today is my day 22, and I at last feel peace, joy, and motivation again to do things I didn't want to do before. I am eating less, not so hungry, stopped smoking, and do not need caffeine to function as I did before. It doesn't have side effects on libido like Paroxetine. So far, it has been worth the wait of 3 weeks of not feeling so well. IT IS WORTH IT. PLEASE HANG IN THERE!! Pray for all to feel happy."

8 / 10
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  • AAn...
  • November 13, 2014

Bupropion "I was on Prozac and felt tired all the time, still depressed, and no sex drive. I thought maybe the dose wasn't enough and I was going through menopause, but the doc put me on Wellbutrin. I'm with the person above, I cannot believe in one day I felt better. I thought it was in my head. I made phone calls I would avoid because of anxiety, I got things done instead of sleep, and I felt so much happier next to my husband. Day two I woke up ready to start the day, completely the opposite of what I had been experiencing. Everyone is different, and you just have to see what works for you. Prozac is in a different class, and I just needed this antidepressant."

10 / 10
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  • Mia...
  • August 7, 2013

Bupropion "I am a 25-year-old woman and started taking this 6 days ago along with clonazepam for anxiety. 300 mg of Bupropion once a day (mornings) and clonazepam twice a day (once in the morning and once in the evening). I have to say that... so far THIS ROCKS. I was suffering from depression, obsessive thoughts, anxiety, and panic attacks for months. I stopped taking Zoloft after a year because I gained 60 lbs on it. Now with Wellbutrin, I have no side effects except loss of appetite and more energy. I feel more energetic, happy (almost 'giddy') and hopeful for the future. My anxiety and depression were debilitating, and this saved my life. I can't wait till the full effects kick in. 6 days in and I feel the difference."

9 / 10
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  • Kat...
  • Taken for less than 1 month
  • July 20, 2014

Bupropion "I am on Day 3 and I am starting to notice some if not all of the effects. My mood is stabilizing and I am finding my motivation returning to me. I need it for when I get into my doctoral program! I can find pleasure in things I enjoy again. I don't have overtly pessimistic and sad thoughts as much. I'm not crying as much. Before I started taking this medicine, I was not at rock bottom, but I did not want to feel awful anymore. Depression is a real disease. The medications do help."

10 / 10
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  • neb...
  • Taken for 6 months to 1 year
  • February 7, 2014

Bupropion "I was diagnosed with major depressive disorder a few years ago. I've tried basically all SSRI antidepressants. They did nothing for me other than make sex impossible, gave me leg tremors, as well as massive weight gain. I switched to Wellbutrin, and my sex drive is back to normal, my weight is dropping, and I feel a lot better. I recommend this medicine to anyone struggling with SSRIs and their many side effects."

9 / 10
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  • gab...
  • Taken for 1 to 6 months
  • March 9, 2020

"Started with 150mg bupropion, then dose increased to 300mg. Was definitely better, but still had down days. Then, my doctor upped it to 450mg. And, boy oh boy, did it work. This is the perfect dosage for me. I haven't had a depressive day ever since. I don't feel like I am in this bad place anymore, dragging myself through life. No more excessive worry and fear, existential emptiness, lack of vitality, self-hatred, social anxiety, etc. After more than a decade, I feel like my 'natural self' on a consistent basis. I wake up feeling refreshed and looking forward to the day. I know I am finally heading in the right direction in life. I am also losing weight. No diets. I simply have no desire to overeat. The only side effect is high sensitivity to caffeine. So I have to avoid it as much as I can, or else I get anxiety. In my experience, this medication has been life-changing. There is hope, because science works! 'All this time I was finding myself. And I didn't know I was lost.' —Avicci"

9 / 10
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  • jaf...
  • April 1, 2013

Bupropion "I'm a 19-year-old college female. I was struggling with anxiety and depression for about six months and went on Zoloft in December 2012. It made me even more depressed, even though it helped with the anxiety. Zoloft also made me a zombie (napping for hours during the day, no motivation to socialize, no motivation to do schoolwork, nothing). I went off it about a month ago and switched to 150mg of Wellbutrin daily. I noticed a difference the FIRST day. It gave me the energy/positivity I have been lacking for months, and I finally am starting to feel like myself again. I recommend it to anyone who Zoloft didn't work for or who needs that extra boost to come out of a fog."

10 / 10
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  • But...
  • Taken for 1 to 2 years
  • October 22, 2013

Bupropion "Bupropion has been the best ad for my very difficult-to-treat atypical depression. I gradually felt improvement as my doctor increased my dosage over the course of the year. It was helping a little when I first started at 150 mg, but I felt it could do far more. It's been amazing at 450 mg, my current dose. I'm level-headed, focused, and not at all exhausted. I was so tired and wanted to sleep. It also helps me with my addiction to food as I've been captive to this my entire life. I'm slowly losing weight because I'm walking a lot more and not binging. I sleep great too, and I do not feel agitated or nervous. I don't want to consume alcohol like I used to either! It's a total different ball game than the SSRIs I've tried! I'm grateful :-)"

9 / 10
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  • Aun...
  • Taken for 1 to 6 months
  • May 29, 2015

Bupropion "I've been on Wellbutrin for 6 months now for anxiety and depression, and I feel AMAZING. I've lost 30 lbs and am still losing, not through any actual work on my part. I just find that I'm not as hungry. I'm full of energy every morning and it lasts all day. I've also noticed an insane increase in libido, and I've easily kicked some bad habits without really trying, like biting my nails. It just doesn't happen anymore. I also don't have any desire for alcohol or cigarettes. For once in my life since starting this long road of antidepressants, I FINALLY feel like this is the one for me. The only negative side effects I have noticed are that my chest and neck stay flushed, and I really do have to remind myself to eat."

9 / 10
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  • Car...
  • Taken for 1 to 6 months
  • April 19, 2017

Bupropion "I have been taking 150 mg of the generic of Wellbutrin for the past month. I can't believe how amazing I feel! After dealing with depression for the past 4-5 years, I finally feel like myself again. I was diagnosed with PMDD and mild depression but tried to deal with both of these with Prozac and hormone birth control. After three months of Prozac, I quit. It made me tired and took away my libido. It didn't help my depression at all. I've tried three different birth controls (I'm 46... it wasn't for birth control, just to try to help my hormone levels.) Nothing helped my depression. Finally, my doctor prescribed Wellbutrin. I filled it but didn't take it for 8 months because I was afraid of the side effects. Now I could just kick myself!"

9 / 10
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  • c3l...
  • May 16, 2013

Bupropion "This medicine really works for me and has really improved my quality of life and perspective on things. I'm 18, and I have been on this for a little over 6 months, and I would say the only bad side effect is dry mouth, but if you just drink a lot of water, you'll be fine. I like it because it has helped me stop 'binge' eating. I don't have cravings for food or cigarettes anymore, and I completely stopped smoking. I'm never tired anymore, Wellbutrin definitely gives you energy in a good way. Sex drive is completely normal, and I still have normal emotions, unlike when I was on Celexa or Prozac where I felt so emotionless. I lost 20 lbs, but I am healthy and fit and a lot happier with myself."

9 / 10
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  • Nob...
  • November 16, 2014

Bupropion "I've been taking this medication for depression. I've been on it for about a year now. When I first started taking it, I smoked about a pack a day. Over time, this reduced my cravings for nicotine and helped me quit smoking. It took time and effort, but it worked. Also, when I started this medicine, I weighed 207 lbs, which was my highest weight. Wellbutrin caused weight loss for me, and I now weigh 165. This medicine improves my overall mood, and I am not as depressed as I was a year ago. I've also experienced hair shedding, which has become more and more of a problem. Sometimes it comes out in handfuls. I gave this medicine a 9 because mostly my side effects were positive. I don't know where I'd be without Wellbutrin."

9 / 10
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  • Anonymous
  • March 18, 2010

Bupropion "I have been taking Wellbutrin continuously for 20 years. If it were not for this miracle drug, I would be dead. There is no doubt in my mind that my intractable depression was arrested with Wellbutrin. I have a chemical imbalance that is permanent. I once went off Wellbutrin for a month because I was taking another medicine. Within three weeks, I was having suicidal ideas. Needless to say, I will not go off it again. My doctor assures me it is safe for lifelong use."

10 / 10
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  • Mea...
  • Taken for less than 1 month
  • September 24, 2018

Bupropion "Have been on Wellbutrin SR 150 twice daily. BEST CHOICE I MADE!! I am a person that thrives off of happiness, feeling great, making others happy, etc! After one week, I am me again!!! HAPPY, SECURE, JUST ME!! I noticed it has helped chill me out. For those who don’t find this medication to work, maybe it is the wrong drug for your chemical imbalance. It is just a matter of finding the right drug for the right person. I'm thankful"

9 / 10
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  • Mea...
  • Taken for less than 1 month
  • September 19, 2018

Bupropion "I tried to get by on 150 mg of bupropion but was getting weepy over little things and decided to ask to up my dosage, and I am now on 300 mg (The other 150 mg in the evening). I went through waking in the night as well as during the day with all kinds of negative feelings and gut-wrenching crying. I really didn’t have side effects... I stayed away from people because I knew I was not quite 'right' and didn’t want to make a 'fool' of myself as I knew my thinking was a little askew. I just today—-24 days into the increase in medication—felt a breakthrough and feel like I have a new lease on life... it is like I was teetering on the edge and have now slipped over into normalcy."

10 / 10
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  • Ste...
  • April 27, 2015

Bupropion "I've been battling moderate anxiety and depression for most of my adult life. I'm 24 now, and since my official diagnosis at age 20, I have tried 4 other medications (Celexa, Zoloft, Paxil, Buspar) and found that each one increased my anxiety or made me a despondent zombie. 3 months ago, my PCP put me on Wellbutrin. Let me tell you, this medication saved my life. I went from spending days lying in bed, smoking weed, having daily panic attacks to waking up with a desire to take on the day. In the few months since I've been on the medication, I've lost 30 pounds. It suppresses the urge to binge eat and provides energy for the gym. My friends said I finally seem like me again. Highly recommended if you hate SSRIs like me!"

9 / 10
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  • Ron...
  • Taken for less than 1 month
  • March 12, 2025

Bupropion "This medication was very hard to use, there was stomach pain and acid reflux. Sleep was poor, and I couldn't sleep more than 2 hours without waking at night. I became very agitated with anxiety and sadness that would come and go very fast. The agitation became worse, and I was looking for anything that irritated me to lash out and went into a rage and confronted others. My heart was always around 100 beats when I was at rest. I also had very strange thoughts that worried me I was losing control of my thoughts."

1 / 10
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  • Tha...
  • November 8, 2016

Bupropion "I've had mild to severe depression my whole life. I was on Prozac from high school to my early 20s. When I was pregnant with my first child, I stopped taking my Prozac. A year ago, I knew it was time to get back on something because my depression was creeping back in. I spoke to my OB/GYN, and she suggested Wellbutrin XL, and OMG! So grateful that she suggested this. I started with 300mg, and now a year and a half later, I'm on 450mg. And let me be honest... losing 35 lbs because of this medication is a PLUS, especially for my depression!"

10 / 10
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  • Pin...
  • Taken for less than 1 month
  • January 30, 2014

Bupropion "I started Wellbutrin SR just last week. I feel 90% better already. Previously I was taking Zoloft and after a year and a half, I felt sluggish, tired, hopeless, and just plain blah. I now don't have constant worrying, it helps with my OCD, and the things that bothered me before have just become basically no big deal to me. I'm happier, I focus much better. And my spirits are brighter than they have been in months!"

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.